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| 1 | Nat Med:靶向两分子或有助于彻底治愈白血病显示文摘科学家在癌细胞内发现两个信号蛋白能够让癌细胞抵抗化疗。研究表明阻断这两种蛋白能够增强化疗对人类白血病小鼠模型的治疗效果。相关研究结果发表在国际学术期刊NatureMedicine上。研究人员发现在治疗中阻断c-Fos和Dusp1这两个蛋白能够治愈一些受激酶驱动且抵抗治疗的白血病和实体瘤。 | Meenu Kesarwani, Zachary Kincaid, Ahmed Gomaa, Erika Huber, Sara Rohrabaugh, Zain Siddiqui, Muhammad F Bouso, Kakajan Komurov, James C Mulloy, Jose A Cancelas, H Leighton Grimes Mohammad Azam Tahir Latif Ming Xu H Leighton Grimes Mohammad Azam | 2017 | 现代生物医学进展2017，17，17： | 4 |
| 2 | Application of Statistically Based Experimental Designs to Optimize Cellulase Production and Identification of Gene显示文摘A natural bacterial strain identified as Bacillus amyloliquefaciens MBAA3 using 16S rDNA partial genome sequencing has been studied for optimization of cellulase production.Statistical screening of media components for production of cellulase by B.amyloliquefaciens MBAA3 was carried out by Plackett–Burman design.Plackett–Burman design showed CMC,MgSO4 and pH as significant components influencing the cellulase production from the media components screened by Plackett-Burman fractional factorial design.The optimum concentrations of these significant parameters were determined employing the response surface central composite design,involving three factors and five levels was adopted to acquire the best medium for the production of cellulase enzyme revealed concentration of CMC(1.84 g),MgSO4(0.275 g),and pH(8.5)in media for highest enzyme production.Response surface counter plots revealed that middle level of MgSO4 and middle level of CMC,higher level of CMC and lower level of pH and higher level of MgSO4 with lower level of pH increase the production of cellulase.After optimization cellulase activity increased by 6.81 fold.Presence of cellulase gene in MBAA3 was conformed by the amplification of genomic DNA of MBAA3.A PCR product of cellulase gene of 1500 bp was successfully amplified.The amplified gene was conformed by sequencing the amplified product and sequence was deposited in the gene bank under the accession number KF929416. | Aarti Thakkar Meenu Saraf | 2014 | Natural Products and Bioprospecting2014，4，6： | 3 |
| 3 | Th17 cells, pathogenic or not? TGF-β3 imposes the embargo显示文摘 | Meenu Sharma | 2013 | Cellular & Molecular Immunology2013，10，2： | 2 |
| 4 | Assessment of groundwater quality with special emphasis on nitrate contamination in parts of Gautam Budh Nagar district,Uttar Pradesh, India显示文摘Progressive developments in industrial and agricultural activities are causing a critical stress on groundwater quality in developing countries.The objective of this paper is to assess and evaluate the contamination level of groundwater caused by leachate in 11 villages of the Gautam Budh Nagar district in Uttar Pradesh,India.We systematically sampled 22 groundwater samples and 13 leachate samples to ascertain the source of pollution on groundwater quality.The standard analytical methods given by the American Public Health Association(APHA)(Standard methods for examination of water and wastewater,23rd edn.APHA,AWWA,WPCF,Washington,2017)were used for quantitative estimation of hydrochemical parameters of collected samples.The results of the analysis of groundwater samples indicate that pH values range from 7.31 to 8.97.The mean magnesium concentration in groundwater samples is 58.93±21.44 mg/L.Out of the groundwater samples taken,approximately 41%and 73%of samples analysis results have been found beyond the acceptable limit with respect to the parameters of turbidity and total dissolved solids,respectively,according to the Bureau of Indian Standards(Indian standard specification for drinking water(IS:10500).BIS,Manak Bhawan,New Delhi,2012)for drinking water.Around 95.4%of groundwater samples and 92.3%of leachate samples have high nitrate concentrations above the standard limit of BIS(45 mg/L),respectively.The Piper plot shows that 50%of the samples belong to the Ca^2+-Mg^2+-HCO3^-type.Ternary and Durov's diagrams indicate that the mean concentrations of ions are in the order of Na^+>Mg^2+>Ca^2+>K^+(for cations)and HCO3^->NO3^->C1^->SO42^->CO32^->F-(for anions)in groundwater of the study area.The spatial variation of the hydrochemical parameters shows that groundwater is heavily contaminated with respect to nitrate.Analytical results indicate that the groundwater of villages Achheja,Bisrakh road,Dujana,Badalpur and Sadopur is not suitable for drinking. | Meenu Agarwal Meenakshi Singh Jakir Hussain | 2019 | Acta Geochimica2019，38，5： | 2 |
| 5 | Corrosion resistance and microstructure of electrodeposited nickel cobalt alloy coatings 显示文摘 | MEENU S S SELVI V E WILLIAM GRIPS V K | 2006 | Surface & Coating Technology2006，201，： | 1 |
| 6 | Influence of SiC, Si3 N4 and Ale 03 Particles on the Structure and Properties of Electrodeposited Ni显示文摘 | Meenu Srivastava William Grips V K Rajam K S | 2008 | Materials Letters2008，62，20： | 1 |
| 7 | Influence of SiC particle size on the structure and tribological properties of Ni–Co composites显示文摘 | Meenu Srivastava V.K. William Grips Anjana Jain K.S. Rajam | 2007 | Surface & Coatings Technology2007，，： | 1 |
| 8 | Ni-Mo-Co Terna- ry Tlloy as a Replacement for Hard Chrome 显示文摘 | MEENU S ANANDAN C WILLIAM V K | 2013 | Applied Surface Science2013，285，： | 1 |
| 9 | Successful Adjustment inIndian Industry: the Case of Ludhiana' s Woolen Knitwear Cluster 显示文摘 | Meenu Tewari | 1999 | Re- gionalScience and Urban Economics1999，，5： | 1 |
| 10 | Establishment of the first international standard for PEGylated granulocyte colony stimulating factor (PEG-G-CSF): Report of an international collaborative study显示文摘 | Meenu Wadhwa Chris Bird Tom Dougall Peter Rigsby Adrian Bristow Robin Thorpe | 2014 | Journal of Immunological Methods2014，，： | 1 |
| 11 | Successful Adjustment in Indian Industry: the Case of Ludhiana' s Woolen Knitwear Cluster显示文摘 | Tewari Meenu | 1999 | World Development1999，27，9： | 1 |
| 12 | Electrodeposition of Ni–Co composites containing nano-CeO 2 and their structure, properties显示文摘 | Meenu Srivastava V.K. William Grips K.S. Rajam | 2010 | Applied Surface Science2010，，： | 1 |
| 13 | Evidence for Altered Numb Isoform Levels in Alzheimers Disease Patients and a Triple Transgenic Mouse Model显示文摘 | Srinivasulu Chigurupati Meenu Madan Eitan Okun Zelan Wei Jogi V. Pattisapu Mohamed R. Mughal Mark P. Mattson Sic L. Chan | 2011 | Journal of Alzheimers Disease2011，，： | 1 |
| 14 | Experimental study and optimization of cutting parameters in machining of super alloy with hybrid ultrasonic method显示文摘 | Dipesh Popli Meenu Gupta | 2017 | Advances in Manufacturing2017，5，3： | 1 |
| 15 | Electrochemical deposition and tribological behavior of Ni and Ni-Co metal matrix composites with SiC nano-particles 显示文摘 | Srivastava Meenu William Grips V K Rajam K S | 2007 | Applied Surface Science2007，253，8： | 1 |
| 16 | Corrosion resistance and microstructure of electrodeposited nickel-cobalt alloy coatings 显示文摘 | Meenu Srivastava Ezhil Selvi V William Grips V K | 2006 | Surface and Coatings Technology2006，201，6： | 1 |
| 17 | Biological activity of interleukins-28 and -29: Comparison with type I interferons显示文摘 | Anthony Meager Kumuthini Visvalingam Paula Dilger Donna Bryan Meenu Wadhwa | 2005 | Cytokine2005，，2： | 1 |
| 18 | Corro- sion resistance and microstructurc of electrodeposited nickel-cobalt alloy coatings 显示文摘 | Meenu S Ezhil S V William G V K | 2006 | Surface & CoatingsTechnology2006，201，： | 1 |
| 19 | The development and function of regulatory T cells显示文摘 | Creg J. Workman Andrea L. Szymczak-Workman Lauren W. Collison Meenu R. Pillai Dario A. A. Vignali | 2009 | Cellular and Molecular Life Sciences2009，，16： | 1 |
| 20 | Dyeing of silk with natural dye extracted from polygonum amplexicaule 显示文摘 | Meenu Srivastava | 2008 | Man - made Textile in India2008，，5： | 1 |
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