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| 1 | Regulation of spermatogenesis by paracrine/autocrine testicular factors显示文摘Spermatogenesis is a complex process regulated by endocrine and testicular paracrine/autocrine factors.Gonadotropins are involved in the regulation of several testicular paracrine factors, mainly of the IL-1 family and testicular hormones. Testicular cytokines and growth factors (such as IL-1, IL-6, TNF, IFN-T, LIF and SCF) were shown to affect both the germ cell proliferation and the Leydig and Sertoli cells functions and secretion. Cytokines and growth factors are produced by immune cells and in the interstitial and seminiferous tubular compartments by various testicular cells, including Sertoli, Leydig, peritubular cells, spermatogonia, differentiated spermatogonia and even spermatozoa. Corresponding cytokine and growth factor receptors were demonstrated on some of the testicular cells. These cytokines also control the secretion of the gonadotropins and testosterone in the testis. Under pathological conditions the levels of pro-inflammatory cytokines are increased and negatively affected spermatogenesis. Thus,the expression levels and the mechanisms involved in the regulation of testicular paracrine/autocrine factors should be considered in future therapeutic strategies for male infertility. (Asian J Androl 2004 Sep; 6: 259-268) | Mahmoud Huleihel Eitan Lunenfeld | 2004 | Asian Journal of Andrology2004,6,3: | 22 |
| 2 | Differentiation of murine male germ cells to spermatozoa n a soft agar culture system显示文摘建立一在里面允许阴囊的细菌房间的发展到精子的 vitro 系统将为男不孕为精子发生和未来治疗的研究是珍贵的。在现在的学习,我们用三维的琼脂文化系统(囊) 处于 vitro 文化条件发展了,它有能力导致阴囊的细菌房间到达精子发生的最后的阶段,包括精子产生。从 7-day-old 老鼠的睾丸的生精的小管酶地被分裂,并且 intratubular 房间在在与胎儿的小牛浆液(FCS ) 补充的 RPMI 媒介的 SACS 的上面的层是有教养的。SACS 的更低的层包含了与 FCS 补充的仅仅 RPMI 媒介。在上面的层的殖民地在文化的 14 和 28 天以后被孤立并且根据他们的尺寸被分类。Immunofluorescence 和即时 PCR 被用来分析在无差别、区分的 spermatogonia 表示的特定的标记(Vasa, Dazl, OCT-4, C 工具包, GFR-α -1, CD9 和 α -6-integrin), meiotic 房间(LDH, Crem-1 和议会) 和 post-meiotic 房间(Protamine-1,精子酵素和 SP-10 ) 。我们的结果表明导致老鼠是可能的阴囊的 pre-meiotic 细菌房间扩大并且在囊导致他们的区别到精子。精子显示出正常形态学并且包含了 acrosomes。因此,我们的结果证明囊能为 pre-meiotic 鼠标细菌房间的成熟在 vitro 系统被用作一篇小说到 post-meiotic 阶段和词法上正常的精子。 | Mahmoud Abu Elhija Eitan Lunenfeld Stefan Schlatt Mahmoud Huleihel | 2012 | Asian Journal of Andrology2012,14,2: | 14 |
| 3 | Does capsule endoscopy have an added value in patients with perianal disease and a negative work up for Crohn's disease?显示文摘AIM:To investigate the role of capsule endoscopy in patients with persistent perianal disease and negative conventional work up for Crohn's disease(CD).METHODS:Patients with perianal disease(abscesses,fistulas,recurrent fissures) were evaluated for underlying CD.Patients who had a negative work up,defined as a negative colonoscopy with a normal ileoscopy or a normal small bowel series or a normal CT/MR enterography,underwent a Pillcam study of the small bowel after signing informed consent.Patients using nonsteroidal anti-inflammatory drugs or who had a history of inflammatory bowel disease or rheumatic disease were excluded.RESULTS:We recruited 26 patients aged 21-61 years(average 35.6 years),17 males and 9 females.One case could not be evaluated since the capsule did not leave the stomach.In 6 of 25(24%) patients with a negative standard work up for Crohn's disease,capsuleendoscopy(CE) findings were consistent with Crohn's disease of the small bowel.Family history of CD,white blood cell,hemoglobin,erythrocyte sedimentation rate or C-reactive protein did not predict a diagnosis of CD.Capsule endoscopy findings led to a change in treatment.CONCLUSION:In patients with perianal disease and a negative conventional work up to exclude CD,CE leads to incremental diagnostic yield of 24%. | Samuel N Adler Metzger Yoav Scapa Eitan Chowers Yehuda Rami Eliakim | 2012 | World Journal of Gastrointestinal Endoscopy2012,4,5: | 4 |
| 4 | Customer Referral Management: Optimal Reward Programs显示文摘 | Eyal Biyalogorsky Eitan Gerstner Barak Libai | 2001 | Marketing Science2001,,1: | 2 |
| 5 | Toll-like receptor signaling in neural plasticity and disease显示文摘 | Eitan Okun Kathleen J. Griffioen Mark P. Mattson | 2011 | Trends in Neurosciences2011,,5: | 2 |
| 6 | Workload analysis of a large-scale key-value store显示文摘 | Berk Atikoglu Yuehai Xu Eitan Frachtenberg Song Jiang Mike Paleczny | 2012 | ACM SIGMETRICS Performance Evaluation Review2012,,1: | 2 |
| 7 | Agile patency system eliminates risk of capsule retention in patients with known intestinal strictures who undergo capsule endoscopy显示文摘 | Juan M. Herrerias Jonathan A. Leighton Guido Costamagna Anthony Infantolino Rami Eliakim Doron Fischer David T. Rubin Howard D. Manten Eitan Scapa Douglas R. Morgan Ari J. Bergwerk Binyamin Koslowsky Samuel N. Adler | 2008 | Gastrointestinal Endoscopy2008,,6: | 2 |
| 8 | From Density to Destiny: Using Spatial Dimension of Sales Data for Early Prediction of New Product Success显示文摘 | Tal Garber Jacob Goldenberg Barak Libai Eitan Muller | 2004 | Marketing Science2004,,3: | 2 |
| 9 | Spontaneous and therapeutic abortions and the risk of breastcancer among BRCA1mutation carriers显示文摘 | Eitan Friedman Joanne Kotsopulos Jan Lubinski | 2006 | Breast Cancer Res2006,15,8: | 1 |
| 10 | Laparoscopic adnexal trans- position: novel surgical technique 显示文摘 | Eitan R Krissi H Belier U | 2011 | Int J Gynecol Cancer2011,21,: | 1 |
| 11 | Slezak, An equilibrium model of incentive contracts in the presence of information manipulation显示文摘 | Goldman Eitan and Steve L | 2006 | Journal of Finaneial Economies2006,,80: | 1 |
| 12 | Surface modification of muhi-walled carbon nanotubes: toward the tailoring of the interface in polymer composites 显示文摘 | Eitan A Jiang K Y Dukes D | 2003 | Chemistry of Materials2003,15,16: | 1 |
| 13 | Recognition of motion blurred images by use of the method of moments 显示文摘 | Stem Adrian Kruchakov Inna Yoavi Eitan | 2002 | Applied Optics2002,41,11: | 1 |
| 14 | Direct observation of pol- ymer sheathing in carbon nanotube-polycarbonate composites 显示文摘 | Ding W Eitan A Fisher F T | 2003 | Nano Lett2003,3,11: | 1 |
| 15 | Cyclic pricing by a durable goods monopolist显示文摘 | John Conlisk Eitan Gerstner Joel Sobel | 1984 | The Quarterly Journal of Economics1984,4,: | 1 |
| 16 | The use of skin substitutes in the treatment of the hand and upper extremity显示文摘 | John T. Capo Kyle P. Kokko Marco Rizzo Julie E. Adams Ben Shamian Brenon Abernathie Eitan Melamed | 2014 | HAND2014,,2: | 1 |
| 17 | Optimal Search in Trees显示文摘 | Yosi Ben-Asher Eitan Farchi Ilan Newman | 1999 | SIMA Journal on Computing1999,28,6: | 1 |
| 18 | Management of cervical carcinoma di-agnosed during pregnancy 显示文摘 | Eitan R Abu - Rustum NR | 2003 | Prim Care Update Ob/Gyns2003,10,4: | 1 |
| 19 | Tumor microRNA expression patterns associated with resistance to platinum based chemotherapy and survival in ovarian cancer patients显示文摘 | Eitan R Kushnir M Lithwick-Yanai G | 2009 | Gynecol Oncol2009,114,2: | 1 |
| 20 | Innovation diffusion and new product growth models: A critical review and research directions显示文摘 | Renana Peres Eitan Muller Vijay Mahajan | 2010 | International Journal of Research in Marketing2010,,2: | 1 |