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| 1 | Whole brain radiation therapy with or without stereotactic radiosurgery boost for patients with one to three brain metastases: phase III results of the RTOG 9508 randomised trial显示文摘 | David W Andrews Charles B Scott Paul W Sperduto Adam E Flanders Laurie E Gaspar Michael C Schell Maria Werner-Wasik William Demas Janice Ryu Jean-Paul Bahary Luis Souhami Marvin Rotman Minesh P Mehta Walter J Curran | 2004 | The Lancet . 2004 (9422)2004,,9422: | 2 |
| 2 | Gastric food retention at endoscopy is associated with severity of liver cirrhosis显示文摘BACKGROUND Gastrointestinal symptoms are prevalent in patients with cirrhosis.Cirrhotic patients have a known predilection to delayed gastric emptying compared to those without cirrhosis.However,the contributing factors have not been fully elucidated.Retained gastric food on esophagogastroduodenoscopy(EGD)has been used as a surrogate marker for delayed gastric emptying with reasonably high specificity.Therefore,we hypothesize that the frequency of retained gastric food contents at EGD will be higher in a cirrhotic population compared to a control population without liver disease.Additionally,we hypothesize that increased frequency of gastric food contents will be associated with increased severity of cirrhosis.AIM To determine the relative frequency of delayed gastric emptying among cirrhotics as compared to non-cirrhotics and to identify associated factors.METHODSWe performed a retrospective case-control study of cirrhotic subjects whounderwent EGD at an academic medical center between 2000 and 2015. Threehundred sixty-four patients with confirmed cirrhosis, who underwent a total of1044 EGDs for the indication of esophageal variceal screening or surveillance,were identified. During the same period, 519 control patients without liverdisease, who underwent a total of 881 EGDs for the indication of anemia, wereidentified. The presence of retained food on EGD was used as a surrogate fordelayed gastric emptying. The relative frequency of delayed gastric emptyingamong cirrhotics was compared to non-cirrhotics. Characteristics of patients withand without retained food on EGD were compared using univariable andmultivariable logistic regression analysis to identify associated factors.RESULTSOverall, 40 (4.5%) patients had evidence of retained food on EGD. Cirrhotics weremore likely to have retained food on EGD than non-cirrhotics (9.1% vs 1.4%, P <0.001). Characteristics associated with retained food on univariable analysisincluded age less than 60 years (12.6% vs 5.2%, P = 0.015), opioid use (P = 0.004),Child-Pugh class C (24.1% Child-Pugh class C vs 6.4% Child-Pugh class A, P =0.007), and lower platelet count (P = 0.027). On multivariate logistic regressionanalysis, in addition to the presence of cirrhosis (adjusted OR = 5.83;95%CI: 2.32-14.7, P < 0.001), diabetes mellitus (types 1 and 2 combined) (OR = 2.34;95%CI:1.08-5.06, P = 0.031), opioid use (OR = 3.08;95%CI: 1.29-7.34, P = 0.011), andChild-Pugh class C (OR = 4.29;95%CI: 1.43-12.9, P = 0.01) were also associatedwith a higher likelihood of food retention on EGD.CONCLUSIONCirrhotics have a higher frequency of retained food at EGD than non-cirrhotics.Decompensated cirrhosis, defined by Child-Pugh class C, is associated with ahigher likelihood of delayed gastric emptying. | David B Snell Shirley Cohen-Mekelburg Russell Weg Gaurav Ghosh Adam P Buckholz Amit Mehta Xiaoyue Ma Paul J Christos Arun B Jesudian | 2019 | World Journal of Hepatology2019,11,11: | 2 |
| 3 | Cracking - corrosion interaction inconcrete exposed to marine environment 显示文摘 | MEHTA P K GERWICK B C | 1982 | Concrete Interna- tional1982,4,10: | 1 |
| 4 | Poly ( amidoamine ) Dendrimer-Based Multifunctional Engineered Nanodevice for Cancer Therapy 显示文摘 | Majoros I J Thomas T P Mehta C B | 2005 | Journal of Medicinal Chemistry2005,48,: | 1 |
| 5 | Pheno: typic characterization and identification of effector cells involved in tunor cell recognition of cytokine induced kil- ler cells显示文摘 | Schmidt-Wolf I G Lefterova P Mehta B A | 1993 | Exp Hematol1993,21,13: | 1 |
| 6 | Increeased serum neopterin leveels in adults with Donm syndrome 显示文摘 | Mehta P D Patarick B A Dalton A J | 2005 | J Neuroimmunol2005,164,2: | 1 |
| 7 | 查看详情显示文摘 | Haynam C A Wegner P J Auerbach J M Bowers M W Dixit S N Erbert G V Heestand G M Henesian M A Hermann M R Jancaitis K S Manes K R Marshall C D Mehta N C Menapace J Moses E Murray J R Nostrand M C Orth C D Patterson R SacksR A Shaw M J Spaeth M Sutton S B W | | 0,,: | 1 |
| 8 | Poly(amidoamine) dendrimer-based multifunctional engineered nanodevice for cancer therapy显示文摘 | MAJOROS I J THOMAS T P MEHTA C B | | 0,,19: | 1 |
| 9 | TNF-alpha inhibitor etanercept and hematologic malignancies:report of a case and review of the literature显示文摘 | Nair B Raval G Mehta P | 2007 | Am J Hernatol2007,82,10: | 1 |
| 10 | Phenotypic char- acterization and identification of effector ceils involved in tumor cell recognition of cytokine-induced killer cells显示文摘 | Schmidt-Wolf I G Lefterova P Mehta B A | 1993 | Exp Hematol1993,21,13: | 1 |
| 11 | Doselimiting toxicity after hypofractionated dose-escalated radiotherapy in non-small-cell lung cancer 显示文摘 | CANNON D M MEHTA M P ADKISON J B | 2013 | J Clin Oncol2013,31,34: | 1 |
| 12 | Increased serum neop- terin levels in adults with down syndrome 显示文摘 | Mehta P D Patrick B A Dalton A J | 2005 | J Neuroimmtmol2005,164,2: | 1 |
| 13 | Assessment of the biodegradability of mineral oil and synthetic ester based stock using CO2ultimate biodegradability tests and CEC-L33-T-82显示文摘 | Novick N J Mehta P G Mcgoldrick P B | 1996 | Syn Lubr1996,13,1: | 1 |
| 14 | Role of isocitrate dehydrogenase in glioma 显示文摘 | Alexander B M Mehta M P | 2011 | Expert Rev Neurother2011,11,10: | 1 |
| 15 | Double-dose versus standard-dose clopidogrel and high-dose versus low-dose aspirin in individuals undergoing percutaneous coronary intervention for acute coronary syndromes (CURRENT-OASIS 7): a randomised factorial trial显示文摘 | Shamir R Mehta Jean-Francois Tanguay John W Eikelboom Sanjit S Jolly Campbell D Joyner Christopher B Granger David P Faxon Hans-Jurgen Rupprecht Andrzej Budaj Alvaro Avezum Petr Widimsky Philippe Gabriel Steg Jean-Pierre Bassand Gilles Montalescot Carlos | 2010 | The Lancet2010,,9748: | 1 |
| 16 | Evaluation of the osteoporotic proximal humeral fracture and strate?gies for structural augmentation during surgical treat?ment显示文摘 | SURENA N VOLETI P B MEHTA S | 2010 | J Shoulder Elbow Surg2010,21,: | 1 |
| 17 | Double-dose versus standard-dose clopidogrel and high-dose versus low-dose aspirin in individuals undergoing percutaneous coronary intervention for acute coronary syndromes (CURRENT-OASIS 7): a randomised factorial trial显示文摘 | Shamir R Mehta Jean-Francois Tanguay John W Eikelboom Sanjit S Jolly Campbell D Joyner Christopher B Granger David P Faxon Hans-Jurgen Rupprecht Andrzej Budaj Alvaro Avezum Petr Widimsky Philippe Gabriel Steg Jean-Pierre Bassand Gilles Montalescot Carlos | 2010 | The Lancet2010,,9748: | 1 |
| 18 | Assessment of the bio- degradability of mineral oil and synthetic ester based stock using CO2 ultimate biodegradability tests and CEC-L33-T-82 显示文摘 | Novick N J Mehta P G McGoldrick P B | 1996 | Journal of Synthetic Lubrication1996,13,1: | 1 |
| 19 | Combined administration of a chelating agent and antioxidant in the prevention and treatment of acute lead intoxication in rats 显示文摘 | Pande M Mehta A Pant B P | 2001 | Environ Toxicol2001,9,4: | 1 |
| 20 | Fenestration of intraeranial arteries with special attention to associated aneurysms and other anomalies显示文摘 | Sanders W P Sorek P A Mehta B A | 1993 | AJNR1993,14,3: | 1 |