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| 1 | Recent advances in microsystem approaches for mechanical characterization of soft biological tissues显示文摘Microsystem technologies for evaluating the mechanical properties of soft biological tissues offer various capabilities relevant to medical research and clinical diagnosis of pathophysiologic conditions.Recent progress includes(1)the development of tissue-compliant designs that provide minimally invasive interfaces to soft,dynamic biological surfaces and(2)improvements in options for assessments of elastic moduli at spatial scales from cellular resolution to macroscopic areas and across depths from superficial levels to deep geometries.This review summarizes a collection of these technologies,with an emphasis on operational principles,fabrication methods,device designs,integration schemes,and measurement features.The core content begins with a discussion of platforms ranging from penetrating filamentary probes and shape-conformal sheets to stretchable arrays of ultrasonic transducers.Subsequent sections examine different techniques based on planar microelectromechanical system(MEMS)approaches for biocompatible interfaces to targets that span scales from individual cells to organs.One highlighted example includes miniature electromechanical devices that allow depth profiling of soft tissue biomechanics across a wide range of thicknesses.The clinical utility of these technologies is in monitoring changes in tissue properties and in targeting/identifying diseased tissues with distinct variations in modulus.The results suggest future opportunities in engineered systems for biomechanical sensing,spanning a broad scope of applications with relevance to many aspects of health care and biology research. | Enming Song Ya Huang Ningge Huang Yongfeng Mei Xinge Yu John A.Rogers | 2022 | Microsystems & Nanoengineering2022，8，4： | 0 |
| 2 | 6-27 Structural Design of ADS-L60 Superconducting Magnets显示文摘Accelerator driven system (ADS) is the effective tool for transmuting the long-lived transuranic radionuclidesinto shorter-lived radionuclides. A project called C-ADS is being studied at the Chinese Academy of Sciences.Injector II prototype of C-ADS which is in charge of by the Institute of Modern Physics has already gained agood progress so far. Two superconducting solenoids with the effective length of 150 mm have been designed andfabricated by Magnet and Mechanical Group of IMP and installed into the testing cryomodule[1]. | Mei Enming Wu Wei Wu Beimin Yan Tongjun | 2014 | IMP & HIRFL Annual Report2014，，1： | 0 |
| 3 | BCL9 regulates CD226 and CD96 checkpoints in CD8^(+)T cells to improve PD-1 response in cancer显示文摘To date,the overall response rate of PD-1 blockade remains unsatisfactory,partially due to limited understanding of tumor immune microenvironment(TIME).B-cell lymphoma 9(BCL9),a key transcription co-activator of the Wnt pathway,is highly expressed in cancers.By genetic depletion and pharmacological inhibition of BCL9 in tumors,we found that BCL9 suppression reduced tumor growth. | Mei Feng Zhongen Wu Yan Zhou Zhuang Wei Enming Tian Shenglin Mei Yuanyuan Zhu Chenglong Liu Fenglian He Huiyu Li Cao Xie Joy Jin Jibin Dong Dehua Yang Ker Yu Junbin Qian Diether Lambrechts Ming-Wei Wang Di Zhu | 2021 | Signal Transduction and Targeted Therapy2021，6，9： | 0 |
| 4 | Introduction of Magnet Division's Key Work in 2019显示文摘Last year,the MTG(Magnet Technology Group)undertaken the magnet development formany accelerators such as High Intensity heavy ion Accelerator Facility(HIAF),China initiative Accelerator Driven System(CiADS),Space.Environment Simulation and Research Infrastructure(SESRI). | Yao Qinggao Wu Wei Yang Wenjie Ni Dongsheng Zhang Xiang Zhang Jingjing Mei Enming Feng Wentian | 2019 | IMP & HIRFL Annual Report2019，，1： | 0 |
| 5 | Technology Exploration of DCT/CCT Magnet Based on Addition and Reduction Composite Material显示文摘Puremultipolar magnetic field is an ideal field derived from the formula and it is very useful for scientific research Discrete-Cosine-Theta(DCT)and Canted-Cosine-Theta(CCT)coils as shown in Figs. | Mei Enming Liang Yu Chen Yuquan Wu Wei | 2019 | IMP & HIRFL Annual Report2019，，1： | 0 |
| 6 | Quench Analysis of CiADS Superconducting Magnet显示文摘The models of quench analysis of CiADS superconducting magnets are displayed in Fig.1.Three structures of superconducting magnet are designed and the stored energies are 6.5 kJ for sol.1. | Zheng Shijun Yang Tongjun Wu Wei Chen Yuquan Wu Beimin Mei Enming | 2019 | IMP & HIRFL Annual Report2019，，1： | 0 |
| 7 | Mechanical Design of the Full-length Magnet Mirror Structure for a Nbg_(3)Sn Sextupole Coil of FECR显示文摘The fourth-generation 45 GHz ECR source(FECR)is under development in the Institute of Modern Physics.One of the critical components of FECR is the Nb_(3)Sn sextupole coil with a length of 937.4 mm. | Zhu Li Chen Yuquan Mei Enming Wu Wei Sun Liangting | 2019 | IMP & HIRFL Annual Report2019，，1： | 0 |
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