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1Effect of dietary soy oil, glucose, and glutamine on growth performance, amino acid profile, blood profile, immunity, and antioxidant capacity in weaned piglets显示文摘Weaning stress results in gastrointestinal dysfunction and depressed performance in pigs. This study aimed to investigate the effect of soy oil, glucose, and glutamine on the growth and health of weaned piglets. Compared with those in the glutamine group, piglets in the glucose and soy oil groups had greater average daily gain, average daily feed intake, and gain: feed ratio from day 0 to 14, and gain: feed ratio for the overall period. There were no differences with regard to serum amino acids among the three groups on day 14, except glycine and threonine. The serum concentration of histidine, serine, threonine, proline, and cysteine was the highest in the glutamine group, while the content of glycine and lysine in the soy oil group on day 28 was the highest among all groups. Piglets fed with glutamine had greater serum glucose and creatinine on day 14, high-density lipoprotein on day 28, and serum IgG and IgM on day 28. Piglets in the glutamine group demonstrated lower serum total superoxide dismutase on day 14 and 28; however, they demonstrated higher total superoxide dismutase and total antioxidant capacity in the duodenum and ileum on day 14. Weaned pigs supplemented with glucose or soy oil demonstrate better growth performance possibly due to their enhanced feed intake, whereas those supplemented with glutamine may have improved immunity and intestinal oxidative capacity.Dinghong Lv Xia Xiong Huansheng Yang Meiwei Wang Yijie He Yanhong Liu Yulong Yin 2018Science China(Life Sciences)2018,61,10:20
2High-speed colour-converting photodetector with all-inorganic CsPbBr_(3) perovskite nanocrystals for ultraviolet light communication显示文摘Optical wireless communication(OWC)using the ultra-broad spectrum of the visible-to-ultraviolet(UV)wavelength region remains a vital field of research for mitigating the saturated bandwidth of radio-frequency(RF)communication.However,the lack of an efficient UV photodetection methodology hinders the development of UV-based communication.The key technological impediment is related to the low UV-photon absorption in existing silicon photodetectors,which offer low-cost and mature platforms.To address this technology gap,we report a hybrid Sibased photodetection scheme by incorporating CsPbBr_(3) perovskite nanocrystals(NCs)with a high photoluminescence quantum yield(PLQY)and a fast photoluminescence(PL)decay time as a UV-to-visible colourconverting layer for high-speed solar-blind UV communication.The facile formation of drop-cast CsPbBr_(3) perovskite NCs leads to a high PLQY of up to ~73% and strong absorption in the UV region.With the addition of the NC layer,a nearly threefold improvement in the responsivity and an increase of ~25% in the external quantum efficiency(EQE)of the solar-blind region compared to a commercial silicon-based photodetector were observed.Moreover,timeresolved photoluminescence measurements demonstrated a decay time of 4.5 ns under a 372-nm UV excitation source,thus elucidating the potential of this layer as a fast colour-converting layer.A high data rate of up to 34 Mbps in solar-blind communication was achieved using the hybrid CsPbBr_(3)-silicon photodetection scheme in conjunction with a 278-nm UVC light-emitting diode(LED).These findings demonstrate the feasibility of an integrated high-speed photoreceiver design of a composition-tuneable perovskite-based phosphor and a low-cost silicon-based photodetector for UV communication.Chun Hong Kang Ibrahim Dursun Guangyu Liu Lutfan Sinatra Xiaobin Sun Meiwei Kong Jun Pan Partha Maity Ee-Ning Ooi Tien Khee Ng Omar F.Mohammed Osman M.Bakr Boon S.Ooi 2019Light(Science & Applications)2019,8,1:14
3Dietary high protein-induced diarrhea and intestinal inflammation by activation of NF-kB signaling in piglets显示文摘The present study aimed to investigate whether inflammation-associated responses in piglets are induced by high protein(HP)through activating nuclear factor kappa B(NF-κB)signaling.Sixteen piglets(35 d of age,Duroc×[Landrace×Yorkshire],weaned at d 21,initial BW=9.70±0.11 kg)were allocated to 18%and 26%CP(HP group)at random,comprising 8 replicate pens per treatment.The piglets were slaughtered to collect intestinal tissues when apparent,persistent,and stable diarrhea syndromes happened(on d 12).No significant differences were observed in their growth performance(P>0.05),but reduction by 19.11%,25.31%,23.64%of ADFI,ADG,and G:F,respectively was detected in the HP group.The HP group had greater(P=0.002)diarrhea rates.Furthermore,dietary HP had lower ileal villus height(VH;P=0.048),ratio of villus height to crypt depth(VH/CD ratio;P=0.016),and colonic CD(P=0.034),as well as had the trend(P=0.075)to reduce the ileal villus absorptive area.Moreover,HP diets significantly elevated the goblet cell numbers in the ileal villi(P=0.016)and colonic crypts(P<0.001)and up-regulated(P=0.012)the mRNA expression of mucin2(Muc2)in the ileum.In addition,HP diets increased the myeloperoxidase concentration in the ileum(P=0.002)and colon(P=0.007)of piglets.Dietary HP significantly down-regulated the mRNA expression of tumor necrosis factor-α(TNF-α;P<0.001)in the ileum,induced nitric oxide synthase(iNOS;P=0.040)and interleukin-22(IL-22;P=0.008)in the colon,and inclined to down-regulate interleukin-1β(IL-1β;P=0.076)expression in the colon.The relative protein abundance of Galectin-3(P=0.046)in the colon and the ratio of phosphorylation NF-κB to NF-κB(p-NF=κB/NF-κB ratio)in the ileum of HP piglets were also greater(P=0.038).These results suggest that dietary HP may cause diarrhea in piglets by activating NF-icB signaling induced intestinal inflammation.Lanmei Yin Jun Li Meiwei Wang Qiye Wang Jianzhong Li Nengshui Ding Huansheng Yang Yulong Yin 2021Animal Nutrition2021,,4:3
4UPLC-MS metabolomics provides insights into the diff erences between black- and white-shelled Pacifi c oysters Crassostrea gigas显示文摘A variety of shell colors are one of the most fundamental characteristics of molluscs,which have importantly ecological and economic signifi cance.The Pacifi c oyster Crassostrea gigas is distributed in many sea areas around the world and also an aquacultured mollusc with high nutritional value.In this study,the whole soft body and the mantle tissue of black-shelled Pacifi c oyster(BSO)and white-shelled Pacifi c oyster(WSO)with starkly diff erent melanin contents were compared,and the diff erences in physiology and metabolism between BSO and WSO were analyzed.The results of physiological indicators suggested BSO show more melanin,more dry matter,more crude lipid content,and stronger ability to scavenge free radicals than WSO.The altered metabolites of glycerophospholipids,fatty acyls,and steroids revealed diff erent regulatory mechanisms of lipids.The correlation analysis of metabolomics and previously published RNAseq data suggested that BSO and WSO mainly diff ered in the basal metabolic processes,such as lipid,amino acid and purine metabolisms.This study provides insights into the changes in the physiological indictors and the metabolites of oysters with varying melanin content.Xi CHEN Qiuyun JIANG Hongce SONG Lingling LI Chaoyi XIE Baoyu HUANG Yaqiong LIU Meiwei ZHANG Lei WEI Xiaotong WANG 2021Journal of Oceanology and Limnology2021,39,1:2
5The effect of turbulence on NLOS underwater wireless optical communication channels [Invited]显示文摘Conventional line-of-sight underwater wireless optical communication(UWOC)links suffer from huge signal fading in the presence of oceanic turbulence due to misalignment,which is caused by variations in the refractive index in the water.Non-line-of-sight(NLOS)communication,a novel underwater communication configuration,which has eased the requirements on the alignment,is supposed to enhance the robustness of the UWOC links in the presence of such turbulence.This Letter experimentally and statistically studies the impact of turbulence that arises from temperature gradient variations and the presence of different air bubble populations on NLOS optical channels.The results suggest that temperature gradient-induced turbulence causes negligible signal fading to the NLOS link.Furthermore,the presence of air bubbles with different populations and sizes can enhance the received signal power by seizing the scattering phenomena from an ultraviolet 377 nm laser diode.Mohammed Sait Xiaobin Sun Omar Alkhazragi Nasir Alfaraj Meiwei Kong Tien Khee Ng Boon S.Ooi 2019Chinese Optics Letters2019,17,10:2
6Early diagnosis of bacterial and fungal infection in chronic cholestatic hepatitis B显示文摘AIM: To investigate the early diagnostic methods of bacterial and fungal infection in patients with chronic cholestatic hepatitis B.METHODS: One hundred and one adult in-patients with chronic hepatitis B were studied and divided into 3 groups:direct bilirubin (DBil)/total bilirubin (TBil)≥0.5, without bacterial and fungal infection (group A, n=-38); DBil/TBil<0.5, without bacterial and fungal infection (group B, n=23),DBil/TBil≥0.5, with bacterial or fungal infection (group C,rr=-40). The serum biochemical index and pulse rate were analyzed.RESULTS: Level of TBil, DBil, alkaline phosphatase (ALP) and DBiI/ALP in group A increased compared with that in group B. The level of ALP in group C decreased compared with that in group A, whereas the level of TBil, DBil and DBiI/ALP increased (ALP: 156+43, 199+68, respectively,P<0.05, TBil: 370+227, 220+206, respectively, P<0.01,DBil: 214+143, 146+136, respectively, P<0.01, DBiI/ALP:1.65+1.05, 0.78+0.70, respectively, P<0.001). The level of DBil and infection affected DBiI/ALP. Independent of theeffect of DBil, infection caused DBiI/ALP to rise (P<0.05).The pulse rate in group A decreased compared with that in group B (63.7+6.4, 77.7+11.4, respectively, P<0.001),and the pulse rate in group C increased compared withthat in group A (81.2+12.2, 63.7+6.4, respectively, P<0.001).The equation (infection=0.218 pusle rate +1.064 DBiI/ALP-16.361), with total accuracy of 85.5%, was obtained from stepwise logistic regression. Pulse rate (≥80/min) andDBiI/ALP (≥1.0) were used to screen infection. The sensitivity was 62.5% and 64.7% respectively, and the specificity was 100% and 82.8% respectively.CONCLUSION: Bacterial and fungal infection deterioratejaundice and increase pulse rate, decrease serum ALP andincrease DBiI/ALP. Pulse rate, DBiI/ALP and the equation(infection=0.218 pusle rate+1.064 DBil/ALP-16.361) arehelpful to early diagnosis of bacterial and fungal infectionin patients with chronic cholestatic hepatitis B.Xiong-ZhiWu DanChen Lian-SanZhao Xiao-HuiYu MeiWei YanZhao QingFang Qianxu 2004World Journal of Gastroenterology2004,10,15:1
7Talking about English Etymology显示文摘Sun Meiwei 0,,02:1
8Present Situation of Core Mercury Injection Technology of Unconventional Oil and Gas Reservoir显示文摘Unconventional oil and gas step into a new area of global oil and gas exploration due to the success of the development of shale gas of America.Unconventional tight reservoir has huge differents with conventional reservoirs,including cell aggregation,migration patterns,source configuration storage,reservoir characteristics,flow mechanism and so on,whichGU Meiwei LU Shuangfang XIAO Dianshi GUO Siqi ZHANG Luchuan 2015Acta Geologica Sinica(English Edition)2015,89,A01:1
9Prediction of Total Organic Carbon Content Based on Geostatistical Inversion:A Case of Qingshankou Formation in Wangfu Depression,Songliao Basin显示文摘Currently,there are two main methods to obtain total organic carbon(TOC)content in mud shale:geochemical analysis andΔlg R model.Geochemical analysis can obtain accurate TOC content,but it has the problem of higher cost and less samples.TheΔlg R model can obtain TOC content variable values in well profile conveniently and quickly,but it can’t predict TOC content in mud shale inZHANG Luchuan LU Shuangfang XIAO Dianshi GUO Siqi GU Meiwei 2015Acta Geologica Sinica(English Edition)2015,89,A01:0
10A secreted phospholipase A_(2) (BmsPLA_(2)) regulates melanization of immunity through BmDDC in the silkworm Bombyx mori显示文摘Insect immune-associated phospholipase A_(2) (PLA_(2)) is an important target of pathogen invasion. Melanization, an effective defense response, has significant correlations with other immune responses to coordinate immune attack against invaders. However, the effect of PLA_(2) on melanization has not yet been reported in insects or other arthropods. In this work, we cloned a PLA_(2) gene (BmsPLA_(2)), and its protein had characteristic features of secreted PLA_(2) (sPLA_(2)). After injection of bacteria, BmsPLA_(2) expression and sPLA_(2) activity in hemolymph significantly increased. BmsPLA_(2) fluorescence was transferred from the cytoplasm to the cell membranes of circulating hemocytes. These results indicated that BmsPLA_(2) was related to hemolymph immunity in silkworms. Interestingly, reducing BmsPLA_(2) by RNA interference decreased melanosis (melanistic hemocytes) levels in vivo and in vitro, while BmsPLA_(2) overexpression had the opposite effect. The larval survival and melanization rate in the hemocoel both slowed depending on the PLA_(2) inhibitor dosage. These results demonstrated that BmsPLA_(2) plays a role in melanization during the immune process of silkworms. Surprisingly, the level of BmDDC matched the degree of melanization in various observations. BmDDC expression showed a significant increase, with the peak occurring later than that of BmsPLA_(2) after injection of bacteria, implying that BmsPLA_(2) was activated prior to BmDDC. Moreover, the alteration of BmsPLA_(2) by RNA interference or overexpression led to altered BmDDC levels. These results suggested that BmsPLA_(2) regulates the melanization response in silkworms through BmDDC. Our study proposes a new regulatory mechanism of the melanization response and new directions for understanding the complex immune networks of insects.Tian Li Gemin Wang Wei He Guiqin Li Chunyang Wang Jiamei Zhao Pan Chen Meiwei Guo Ping Chen 2023Insect Science2023,30,6:0
11Application of NMR on Quantificational Characterization of Tight Glutenite Reservoirs Pore Size显示文摘Quantificational characterization of the microscopic pore structure is the key to evaluating tight reservoirs.Since tight reservoirs mainly develop nano-pores which are difficult to fully characterize pore throats’distribution by single conventional experimental method,there’s an urgent need to establish a characterization method by jointing several conventional experimental methods.The tight gas of Shahezi Formation in XujiaweiziGUO Siqi LU Shuangfang XIAO Dianshi ZHANG Luchuan GU Meiwei 2015Acta Geologica Sinica(English Edition)2015,89,A01:0
12Reliability Modeling and Evaluation of Complex Multi-State System Based on Bayesian Networks Considering Fuzzy Dynamic of Faults显示文摘In the traditional reliability evaluation based on the Bayesian method,the failure probability of nodes is usually expressed by the average failure rate within a period of time.Aiming at the shortcomings of traditional Bayesian network reliability evaluation methods,this paper proposes a Bayesian network reliability evaluation method considering dynamics and fuzziness.The fuzzy theory and the dynamic of component failure probability are introduced to construct the dynamic fuzzy set function.Based on the solving characteristics of the dynamic fuzzy set and Bayesian network,the fuzzy dynamic probability and fuzzy dynamic importance degree of the fault state of leaf nodes are solved.Finally,through the dynamic fuzzy reliability analysis of CNC machine tool hydraulic system balance circuit,the application of this method in system reliability evaluation is verified,which provides support for fault diagnosis of CNC machine tools.Fangjun Zuo Meiwei Jia Guang Wen Huijie Zhang Pingping Liu 2021Computer Modeling in Engineering & Sciences2021,,11:0
13miRNA-148b-3p targeting SOCS3 inhibits macrophage M2 polarization by JAK2/STAT3 pathway in immune thrombocytopenia显示文摘Aberrant expression of miRNAs is significantly correlated with the occurrence of immune thrombocytopenic purpura(ITP).The immune imbalance of M1/M2 macrophage contributes to the development of ITP.However,the role of miR-148b-3p in macrophage phenotype imbalance remains unknown in ITP.In this study,we aimed to explore whether miR-148b-3p inhibits M2 macrophage polarization in ITP and to investigate the underlying mechanism.Peripheral blood from 22 ITP patients were collected,and real-time PCR confirmed that miR-148b-3p was upregulated and Western blot analyses detected the expression of SOCS3 was down-regulated.Subsequent dualluciferase reporter gene assay indicated that miR-148b-3p could bind to SOCS3.Furthermore,we found significant correlation between miR-148b-3p expression and platelet count.Applying gain and lose the function experiments of miR-148b-3p and SOCS3,we demonstrated that suppression of miR-148b-3p or up-regulation of SOCS3 promoted macrophage M2 polarization by inhibiting JAK2/STAT3 pathway.Together,our findings demonstrate that that miR-148b-3p targeting SOCS3 inhibits M2 macrophage polarization via JAK2/STAT3 signaling in ITP.YANG YANG LIJUAN FU CHUNMEI CHEN MEIWEI HU 2022BIOCELL2022,46,5:0
14Surface activity of a series of fluoroether betaine amphoteric surfactants: Oxygen roles显示文摘As PFOS, PFOA and their derivatives were banned according to the Stockholm Convention for their potential bioaccumulation and toxicity, people attempted to substitute the legacy fluorosurfactants with short-chain ones. Although short-chain alternatives can alleviate bioaccumulation, surface activity was compromised. Fluorine industry kept seeking for effective solution. In this work, we prepared and investigated a series of fluoroether betaine surfactants for their surface activity and spreading property. The role of oxygen on surface activity was discussed. We found that insertion of oxygen atoms into fluorinated chain could increase hydrophobicity and thus enhance surface activity. The contribution of one oxygen is approximately half of that of a difluoromethylene group by experience. Moreover, introducing oxygen diversified the structure to fill in the gap of surface activity between short and long fluorosurfactants. In summary, this work provided basic knowledge for molecular design.Xue Wang Meiwei Huang Zhaoben Su Libo Qian Yong Guo Qing-Yun Chen Chengying Wu Tao lv Qin Su Qing Shen Jie Ma 2023Chinese Chemical Letters2023,34,3:0
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