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| 1 | 2019新型冠状病毒基因组特征和流行病学:病毒起源和受体结合的意义显示文摘研究者对来自9例新型冠状病毒肺炎住院患者的支气管肺泡灌洗液样本和培养的分离株进行了下一代测序。从这些个体中获得了严重急性呼吸综合征-冠状病毒2(severe acute respiratory syndrome-coronavirus 2,SARS-CoV-2)的完整和部分基因组序列。利用Sanger测序连接病毒重叠群以获得全长基因组,cDNA末端快速扩增确定终端区。对这些SARSCoV-2基因组和其他冠状病毒基因组进行了系统进化分析,以确定该病毒的进化史并有助于推断其可能的起源。 | 刘青(译) 刘莉(审校) Lu R Zhao X Li J Niu P Yang B Wu H Wang W Song H Huang B Zhu N Bi Y Ma X Zhan F Wang L Hu T Zhou H Hu Z Zhou W Zhao L Chen J Meng Y Wang J Lin Y Yuan J Xie Z Ma J Liu WJ Wang D Xu W Holmes EC Gao GF Wu G Chen W Shi W Tan W | 2020 | 中华高血压杂志2020，28，3： | 516 |
| 2 | It is safe to use transdermal glyceryl trinitrate to lower blood pressure in patients with acute ischaemic stroke with carotid stenosis显示文摘Background There is concern that blood pressure(BP)lowering in acute stroke may compromise cerebral perfusion and worsen outcome in the presence of carotid stenosis.We assessed the effect of glyceryl trinitrate(GTN)in patients with carotid stenosis using data from the Efficacy of Nitric Oxide in Stroke(ENOS)Trial.Methods ENOS randomised 4011 patients with acute stroke and raised systolic BP(140-220 mm Hg)to transdermal GTN or no GTN within 48 hours of onset.Those on prestroke antihypertensives were also randomised to stop or continue their medication for 7 days.The primary outcome was the modified Rankin Scale(mRS)at day 90.Ipsilateral carotid stenosis was split:<30%;30-<50%;50-<70%;≥70%.Data are ORs with 95%CIs adjusted for baseline prognostic factors.results 2023(60.5%)ischaemic stroke participants had carotid imaging.As compared with<30%,≥70%ipsilateral stenosis was associated with an unfavourable shift in mRS(worse outcome)at 90 days(OR 1.88,95%CI 1.44 to 2.44,p<0.001).Those with≥70%stenosis who received GTN versus no GTN had a favourable shift in mRS(OR 0.56,95%CI 0.34 to 0.93,p=0.024).In those with 50-<70%stenosis,continuing versus stopping prestroke antihypertensives was associated with worse disability,mood,quality of life and cognition at 90 days.Clinical outcomes did not differ across bilateral stenosis groups.Conclusions Following ischaemic stroke,severe ipsilateral carotid stenosis is associated with worse functional outcome at 90 days.GTN appears safe in ipsilateral or bilateral carotid stenosis,and might improve outcome in severe ipsilateral carotid stenosis. | Jason P Appleton Lisa J Woodhouse Andrew Belcher Daniel Bereczki Eivind Berge Valeria Caso Hui Meng Chang Hanne K Christensen Ronan Collins John Gommans Ann C Laska George Ntaios Serefnur Ozturk Gillian M Sare Szabolcs Szatmari Yongjun Wang Joanna M Wardlaw Nikola Sprigg Philip M Bath for the ENOS investigators | 2019 | Stroke & Vascular Neurology2019，4，1： | 6 |
| 3 | 缺血性脑卒中后的中期血压变异性与临床结局的关系显示文摘本研究旨在探讨急性脑卒中患者发病7d内的中期血压变异性(blood pressure variability,BPV)与预后的关系。方法:本研究纳入873例急性缺血性脑卒中患者。通过计算发病7d内的收缩压和舒张压的变异系数来评价中期BPV。 | Wang Y Wang J Meng P Liu N Ji N Zhang G Xu B Zhou X Sun Y Xu Y Hui R He M 陈云 叶鹏 | 2018 | 中华高血压杂志2018，26，5： | 2 |
| 4 | Influence of Eutrophication on the Distribution of Total Mercury and Methylmercury in Hydroelectric Reservoirs显示文摘 | Meng Bo Feng X B Chen C X Qiu G L Sommar J Guo Y N Liang P Wan Q | 2010 | EN2010，，5： | 2 |
| 5 | 深部地球条件下铁和氧元素的化学变化显示文摘氧与铁分别为地球上丰度最高的元素与占地球质量最大的元素,它们所形成的化合物遍布我们的星球,具有-2价的氧控制着地球的氧逸度,随着深度的增加氧逸度逐渐降低,与铁所形成的氧化物中铁的价态也逐渐降低,O/Fe逐渐增加,近些年来科学家们发现深部地球条件下铁的一系列氧化物,其中具有高压黄铁矿结构的铁超氧化物FeO2具有最高的O/Fe,并且它还能够携带一定量的H(表示为Py-FeO2H,, x=0-1)。 | 夏群科 Liu J Hu Q Y Bi W L Yang L X Xiao Y M Chow P Meng Y.Prakapenka V B Mao H K Mao W L | 2019 | 矿物岩石地球化学通报2019，38，3： | 2 |
| 6 | A thermo-responsive affinity membrane with nano-structured pores and grafted poly(N-isopropylacrylamide) surface layer for hydrophobic adsorption显示文摘 | Meng T Xie R Chen Y C Cheng C J Li P F Ju X J Chu L Y | 2010 | Journal of Membrane Science2010，349，12： | 1 |
| 7 | Coordinated stabilization of tumbling targets using tethered space manipulators 显示文摘 | Wang D K I-Iuang P F Meng Z J | 2015 | IEEE Transactions on Aerospace and Electronic Systems2015，51，3： | 1 |
| 8 | On the nonlinear dynamic behavior of a rotor-bearing system显示文摘 | JING J P MENG G SUN Y | 2004 | Journal of Sound and Vibration2004，274，35： | 1 |
| 9 | 显示文摘 | Meng L Tu J P Liu M S | 1999 | Mater Lett1999，38，2： | 1 |
| 10 | An effective continuum damage mechanics model for creep-fatigue life assessment of a steam turbine rotor显示文摘 | Jing J P Meng G Sun Y | 2003 | International Journal of Pressure Vessels and Piping2003，80，6： | 1 |
| 11 | Grooved Organogel Sur- faces Towards Anisotropic Sliding of Water Droplets 显示文摘 | ZHANG P LIU H MENG J | 2014 | Advanced Materials2014，26，19： | 1 |
| 12 | Structure Effect on Electrical Properties of ITO Films Prepared by RF Reactive Magnetron Sputtering显示文摘 | Meng L J Dos Santos M P | 1996 | Thin Solid Films1996，289，： | 1 |
| 13 | A comparative study of esterase isozymes in 6 species of Apis and 9 genera of Apoidea显示文摘 | LI S W MENG Y P CHANG J T | 1986 | Journal of Apicultural Science1986，，25： | 1 |
| 14 | Uncertainty analysis of irradiance non-uniformity measurementof pulsed solar simulator显示文摘 | He Y W Xiong L M Meng H F Liu D P Zhang J C | 2012 | Proceedings of SPIEThe International Society for Optical Engineering2012，8563，： | 1 |
| 15 | Genetic and experimental evidence for cross -species infection by swine hepatitis E virus显示文摘 | Meng X J Halbur P G Shapiro M S | 1998 | J Virol1998，72，： | 1 |
| 16 | Experimental in fection of pigs with the newly identified swine hepatitis E virus -(swine HEV), but not with human strains of HEV显示文摘 | Meng X J Halbur P G Haynes J S | 1998 | Arch Virol1998，143，14： | 1 |
| 17 | Structural optical and electrical properties of ZnO and ZnO-Al2O3 films prepared by dc magnetron sputtering 显示文摘 | Meng X Q Zhen W Guo J P | 2000 | Appl Phys A2000，70，： | 1 |
| 18 | Effects of polysaccharides from different species of Dendrobium (Shihu) on macrophage function显示文摘 | Meng L Z Lv G P Hu D J | 2013 | Molecules2013，18，5： | 1 |
| 19 | An improved method formeasurement of target-to-background ratio in assessingmediastinal lesions on 18F-FDG coincidence SPECT/CT imaging显示文摘 | WANG P MENG ZW TAN J | 2010 | Nucl Med Commun2010，31，5： | 1 |
| 20 | Sequence comparison of open reading frames 2 to 5 of low and high virulence United States isolates of porcine reproductive and respiratory syndrome virus显示文摘 | Meng X J Paul P S Halbur P G | 1995 | J Gen Virol1995，76，12： | 1 |
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