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| 1 | Genome-wide identification of agronomically important genes in outcrossing crops using OutcrossSeq显示文摘Many important crops(e.g.,tuber,root,and tree crops)are cross-pollinating.For these crops,no inbred lines are available for genetic study and breeding because they are self-incompatible,clonally propagated,or have a long generation time,making the identification of agronomically important genes difficult,particularly in crops with a complex autopolyploid genome.In this study,we developed a method,OutcrossSeq,for mapping agronomically important loci in outcrossing crops based on whole-genome low-coverage resequencing of a large genetic population,and designed three computation algorithms in OutcrossSeq for different types of outcrossing populations.We applied OutcrossSeq to a tuberous root crop(sweet potato,autopolyploid),a tree crop(walnut tree,highly heterozygous diploid),and hybrid crops(double-cross populations)to generate high-density genotype maps for the outcrossing populations,which enable precise identification of genomic loci underlying important agronomic traits.Candidate causative genes at these loci were detected based on functional clues.Taken together,our results indicate that OutcrossSeq is a robust and powerful method for identifying agronomically important genes in heterozygous species,including polyploids,in a cost-efficient way.The OutcrossSeq software and its instruction manual are available for downloading at www.xhhuanglab.cn/tool/OutcrossSeq.html. | Mengjiao Chen Weijuan Fan Feiyang Ji Hua Hua Jie Liu Mengxiao Yan Qingguo Ma Jiongjiong Fan Qin Wang Shufeng Zhang Guiling Liu Zhe Sun Changgeng Tian Fengling Zhao Jianli Zheng Qi Zhang Jiaxin Chen Jie Qiu Xin Wei Ziru Chen Peng Zhang Dong Pei Jun Yang Xuehui Huang | 2021 | Molecular Plant2021，14，4： | 4 |
| 2 | A Smarter Pavlovian Dog with Optically Modulated Associative Learning in an Organic Ferroelectric Neuromem显示文摘Associative learning is a critical learning principle uniting discrete ideas and percepts to improve individuals’adaptability.However,enabling high tunability of the association processes as in biological counterparts and thus integration of multiple signals from the environment,ideally in a single device,is challenging.Here,we fabricate an organic ferroelectric neuromem capable of monadically implementing optically modulated associative learning.This approach couples the photogating effect at the interface with ferroelectric polarization switching,enabling highly tunable optical modulation of charge carriers.Our device acts as a smarter Pavlovian dog exhibiting adjustable associative learning with the training cycles tuned from thirteen to two.In particular,we obtain a large output difference(>10^(3)),which is very similar to the all-or-nothing biological sensory/motor neuron spiking with decrementless conduction.As proof-of-concept demonstrations,photoferroelectric coupling-based applications in cryptography and logic gates are achieved in a single device,indicating compatibility with biological and digital data processing. | Mengjiao Pei Changjin Wan Qiong Chang Jianhang Guo Sai Jiang Bowen Zhang Xinran Wang Yi Shi Yun Li | 2022 | Research2022，，1： | 0 |
| 3 | A Smarter Pavlovian Dog with Optically Modulated Associative Learning in an Organic Ferroelectric Neuromem显示文摘Associative learning is a critical learning principle uniting discrete ideas and percepts to improve individuals’adaptability.However,enabling high tunability of the association processes as in biological counterparts and thus integration of multiple signals from the environment,ideally in a single device,is challenging.Here,we fabricate an organic ferroelectric neuromem capable of monadically implementing optically modulated associative learning.This approach couples the photogating effect at the interface with ferroelectric polarization switching,enabling highly tunable optical modulation of charge carriers.Our device acts as a smarter Pavlovian dog exhibiting adjustable associative learning with the training cycles tuned from thirteen to two.In particular,we obtain a large output difference(>10^(3)),which is very similar to the all-or-nothing biological sensory/motor neuron spiking with decrementless conduction.As proof-of-concept demonstrations,photoferroelectric coupling-based applications in cryptography and logic gates are achieved in a single device,indicating compatibility with biological and digital data processing. | Mengjiao Pei Changjin Wan Qiong Chang Jianhang Guo Sai Jiang Bowen Zhang Xinran Wang Yi Shi Yun Li | 2021 | Research2021，，1： | 0 |
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