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| 1 | One hundred and one over-the-scope-clip applications forsevere gastrointestinal bleeding,leaks and fistulas显示文摘AIM: To investigate the efficacy and clinical outcome of patients treated with an over-the-scope-clip(OTSC) system for severe gastrointestinal hemorrhage, perforations and fistulas.METHODS: From 02-2009 to 10-2012, 84 patients were treated with 101 OTSC clips. 41 patients(48.8%) presented with severe upper-gastrointestinal(GI) bleeding, 3(3.6%) patients with lower-GI bleeding, 7 patients(8.3%) underwent perforation closure, 18 patients(21.4%) had prevention of secondary perforation, 12 patients(14.3%) had control of secondary bleeding after endoscopic mucosal resection or endoscopic submucosal dissection(ESD) and 3 patients(3.6%) had an intervention on a chronic fistula. RESULTS: In 78/84 patients(92.8%), primary treatment with the OTSC was technically successful. Clinical primary success was achieved in 75/84 patients(89.28%). The overall mortality in the study patients was 11/84(13.1%) and was seen in patients with life threatning upper GI hemorrhage. There was no mortality in any other treatment group. In detail OTSC application lead to a clinical success in 35/41(85.36%) patients with upper GI bleeding and in 3/3 patients with lower GI bleeding. Technical success of perforation closure was 100% while clinical success was seen in 4/7 cases(57.14%) due to attendant circumstances unrelated to the OTSC. Technical and clinic success was achieved in 18/18(100%) patients for the prevention of bleeding or perforation after endoscopic mucosal resection and ESD and in 3/3 cases of fistula closure. Two application-related complications were seen(2%).CONCLUSION: This largest single center experience published so far confirms the value of the OTSC for GI emergencies and complications. Further clinical experience will help to identify optimal indications for its targeted and prophylactic use. | Edris Wedi Susana Gonzalez Detlev Menke Elena Kruse Kai Matthes Juergen Hochberger | 2016 | World Journal of Gastroenterology2016，22，5： | 28 |
| 2 | Well-aligned carbon nanotube array membrane synthesized in porous alumina template by chemical vapor deposition显示文摘A new simple approach was developed for preparing well-aligned and monodispersed carbon nanotuoe (CNT) array membrane within the cylindrical pores of anodic aluminum oxide (AAO) template by chemical vapor deposition (CVD). Acetylene and hydrogen were used in the CVD process with Fe-catalyzer at 700℃ under 250 Pa. Scanning electron microscope (SEM) and transmission electron microscope (TEM) were employed to characterize the resulting highly-oriented uniform hollow tube array which had a diameter of about 250 nm, a tube density of 5.3×108cm2 and a length of about 60 μm. The length and diameter of the tubes depend on the thickness and pore diameter of the template. The growth properties of the CNT array film can be achieved by controlling the structure of the template, the particle size of Fe-catalyzer, the temperature in the reactor, the flow ratio and the deposition time. The highly-oriented and uniform CNT array membrane fabricated by this simple method is very much useful in a variety of | Chengwei Wang Menke Li Shanlin Pan Hulin Li | 2000 | Chinese Science Bulletin2000，45，15： | 7 |
| 3 | The estimation of the digestibility and metabolizable energy content of ruminant feedingstuffs from the gas production when they are incubated with rumen liquor in vitro显示文摘 | K. H. Menke L. Raab A. Salewski H. Steingass D. Fritz W. Schneider | 1979 | The Journal of Agricultural Science1979，，： | 4 |
| 4 | 木聚糖酶固态罐发酵及尾气在线测定显示文摘建立了可对 4个各自独立的 2L玻璃发酵罐同时通气培养和尾气检测的固态发酵系统(SSF) ,以 1 0 0g麸皮和 1 0 0g木屑及 1 5 0mLMandels营养盐溶液为培养基进行木霉T6培养 ,在实验条件范围内找出了最佳产木聚糖酶的环境条件 ,即温度为 3 0℃ ,pH6.0 ,接种量 2 5mL/罐 ( 2× 1 0 8~ 4×1 0 8个孢子 /mL) ,通过对木聚糖酶活力和尾气中CO2 变化的连续测定显示 ,菌体CO2 的释放与木聚糖酶合成具有一定的相关性 ,木聚糖酶的合成与尾气中CO2 含量之间存在着滞后关系 ,尾气CO2浓度在发酵 2 6h达到最高值 ,木聚糖酶活力在 3 9h才达峰值。通过对SSF尾气中CO2 的在线测定 。 | 张洁 吴克 刘斌 张敏 Oliver Menke 蔡敬民 Marinus Meiners | 2004 | 食品与发酵工业2004，30，4： | 3 |
| 5 | 钙拮抗剂在恶性肿瘤细胞抑制疗法中的应用显示文摘钙拮抗剂本身并无细胞毒活性,而与某些细胞抑制剂联合应用,则能提高肿瘤细胞对细胞抑制剂的摄取量,并阻滞其细胞外流,从而使细胞内维持高浓度。此外,钙拮抗剂尚能增强肿瘤细胞对细胞抑制剂的敏感性,且能克服细胞的耐药性。这对肿瘤的基础研究及临床化疗均有一定的意义。本文综述了近年来国外的研究进展,并阐述了可能的作用机理。 | Menke H 李青选 | 1989 | 国外医学(药学分册)1989，16，6： | 3 |
| 6 | The clinical spectrum of Castleman’s disease显示文摘 | Angela Dispenzieri James O. Armitage Matt J. Loe Susan M. Geyer Jake Allred John K. Camoriano David M. Menke Dennis D. Weisenburger Kay Ristow Ahmet Dogan Thomas M. Habermann | 2012 | Am. J. Hematol2012，，11： | 3 |
| 7 | Estimation of the energetic feed value obtained from chemical analysis and in vitro gas production using tureen flued显示文摘 | Menke K H Steingass H | 1988 | Animal Research and Development1988，28，： | 1 |
| 8 | Temperature compensation in magnetooptic AC current sensors using an intelligent AC-DC singal evaluation 显示文摘 | Peter Menke Thomas Bosselmann | 1995 | Lightwave Technology1995，13，7： | 1 |
| 9 | A double blind, placebo controlled study of a platelet activating factor antagonist in patients with rheumatoid arthritis显示文摘 | Hilliquin P Chermat-Izard V Menkes CJ | 1998 | J Rheumatol1998，25，8： | 1 |
| 10 | Estimation of the ener- getic feed value obtained from chemical analysis and in vitro gas production using rumen fluid 显示文摘 | MENKE K H STEINGASS H | 1988 | Animal Research and Development1988，28，： | 1 |
| 11 | Impaired wound healing显示文摘 | Menke N B Ward K R WittenTM | 2007 | Clin Dermatol2007，25，1： | 1 |
| 12 | Expression of MTAI promotes motility and invasiveness of PANC--I pancreatic carcinoma cells显示文摘 | Hofer MD Menke A Genze F | 2004 | Br J Cancer2004，90，2： | 1 |
| 13 | Degradation of mixtures of monochlo-rophenols and phenol as substrate for free and immobilized cells of Acaligenes sp, A7-2显示文摘 | Menke B | 1992 | App Microbiol Biotechnol1992，37，： | 1 |
| 14 | Correlation of renal tubular epithelial cell-derived interleukin-18 up-regulation with disease activity in MRL-Faslpr mice with antoimmune lupus nephris显示文摘 | Faust J Menke J Kriegsmann J | 2002 | Arthritis Rheum2002，46，11： | 1 |
| 15 | 2Expression of MTA1 promotesmotility and invasiveness of PANC21 pancreatic carcinoma cells显示文摘 | Hofer MD Menke A | 2004 | B ritish J2 Cancer2004，90，2： | 1 |
| 16 | A new Ammoplanus Gussakovskij (Hymenoptera: Sphecidae: Pemphredoninae) from San Clemente Island, California显示文摘 | Menke A S | 1997 | Proceedings of the Entomological Society of Washington1997，99，： | 1 |
| 17 | The estimation of digestibility and metabolizable energy content of ruminant feedstuffs from gas production when they are incubated with rumen liquor in vitro显示文摘 | Menke K H Roab L Salewski A | 1979 | J Agric Sci1979，193，： | 1 |
| 18 | Nonoperative management of blunt hepatic trauma is the treatment of choice for hemodynami- cally stable patients:results of a prospective trial显示文摘 | Croce MA Fabian TC Menke PG | 1995 | Ann surg1995，221，6： | 1 |
| 19 | Estimation of the energetic feed value obtained from chemical analysis and in vitro gas production using rumen fluid 显示文摘 | Menke K H Steingass H | 1988 | Animal Research Development1988，28，1： | 1 |
| 20 | The CO2 abatement cost curve for the Thailand cement industry显示文摘 | Hasanbeigi A Menke C Price L | 2010 | Journal of Cleaner Production2010，18，15： | 1 |
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