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37篇 您的检索式:作者名="Mills TM"
    题名 作者 年代 出处 被引量
1应用Rho激酶抑制剂对大鼠阴茎勃起的作用显示文摘目的 :探讨将RhoA/Rho激酶抑制剂Y 2 76 32涂抹于阴茎白膜表面以及阴茎龟头皮肤表面有无促进阴茎勃起的作用及其对体循环的影响。 方法 :2 0只成年雄性SD大鼠 ,体重为 2 5 0~ 30 0g ,随机分为实验组和对照组。全身麻醉后颈动脉和海绵体插管连续监测平均动脉压 (MAP)和阴茎海绵体内压 (CCP)的变化。寻找盆腔星状神经节(MPG)并以系列电刺激诱发勃起。向海绵体白膜表面及阴茎龟头皮肤表面涂抹Y 2 76 32 ,观察用药前后阴茎勃起的改变及MAP的改变。 结果 :将Rho激酶抑制剂Y 2 76 32涂抹于大鼠阴茎白膜表面和阴茎龟头皮肤表面均可促进在无阴茎支配神经电刺激下发生勃起 (ICP/MAP明显升高 ) ,在系列电刺激MPG时用药后发生的勃起反应较用药前亦明显增强。表面用药后还发现大鼠体循环血压有不同程度的降低。 结论 :阴茎皮肤表面应用Rho激酶抑制剂是一种安全有效的ED治疗方法 。戴玉田 孙则禹 Chitaley K Webb RC Mills TM Lewis RW 2004中华男科学杂志2004,10,8:5
2Nerve-Sparing Radical Cystectomy and Orthotopic Bladder Replacement in Female Patients显示文摘Bhatta Dhar N Kessler TM Mills RD 2007Eur Urol2007,52,4:1
3Animal models for study of polycystic ovaries and ovarian atresia显示文摘 Mills TM Bagnell CA 1987New York:Plenum Publishing Corp1987,237,:1
4Vasoconstriction,RhoA/Rho-kinase and the erectile response显示文摘Mills TM Lewis RW Wingard CJ 2003Int J Impot Res2003,15,5:1
5Vasoconstrictors in erectile physiology显示文摘Mills TM Chitaley K Lewis RW 2001Int J Impot Res2001,13,5:1
6Effects of castration and androgen replacement on the hemodynamic of penile eructation in the rats 显示文摘Mills TM Stopper VS Wiedmeier VT 1994BiolReprod1994,51,23:1
7Natural and Induced Cadmium-accumulation in Poplar and Willow Im- plication for Phytoremediation 显示文摘Robinson BH Mills TM Petit D 2000Plant and Soil2000,227,:1
8The ups and downs of Rho-kinase and penile erection:upstream regulators and downstream substrates of rho-kinase and their potential role in the eretile response显示文摘Chitaley K Webb RC Mills TM 2003Int J Impot Res2003,15,2:1
9Nitric oxide inhibits RhoA/Rho-kinase signaling to cause penile erection显示文摘Mills TM Chitaley K Lewis RW 2002Eur J Pharmacol2002,439,13:1
10Effects of castration and androgen replacement on the hemodynamics of penile erection in therat显示文摘Mills TM Stopper VS Wiedmeier VT 1994Biol Reprod1994,51,2:1
11RhoA/Rho-kinase:a novel player in the regulation of penile erection显示文摘Chitaley K Webb RC Mills TM 2001Int J Impot Res2001,13,2:1
12Effect of Rho-kinase inhibition on vasoconstriction in the penile circulation显示文摘Mills TM Chitaley K Wingard CJ 2001J Appl Physiol2001,91,3:1
13Continent urinary diversion显示文摘Burkhard FC Kessler TM Mills R 2006Crit Rev Oncol Hematol2006,57,3:1
14Continent urinary diversion显示文摘Burkhard FC Kessler TM Mills R 2006Crit Rev Oncol Hematol2006,57,3:1
15New biochemical pathway may control erection显示文摘Mills TM 2001Scientific World Journal2001,1,:1
16Inhibition of tonic contraction--a novel way to approach erectile dysfunction显示文摘Mills TM Lewis RW Wingard CJ 2002J Androl2002,23,5:1
17The ups and downs of Rho-kinase and penile erection; upstream regulators and downstream substrates of Rho-kinase and their potential role in the erectile response显示文摘Chitaley K Webb RC Mills TM 2003Int J Impot Res2003,15,:1
18Rho-kinase and RGS-containing RhoGEFs as molecular targets for the treatment of erctile dysfunction显示文摘Linder AE Webb RC Mills TM 2005Curr Pharm Des2005,11,31:1
19Nitric oxide inhibits RhoA/Rho-kinase signaling to cause penile erection 显示文摘Mills TM Chitaley K Lewis RW 2002Eur J Pharmacol2002,439,13:1
20Effect of androgens on penile tissue 显示文摘Lewis RW Mills TM 2004Endocrine2004,23,23:1
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