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| 1 | Cooperative Lane-Change Maneuver for Multiple Automated Vehicles on a Highway显示文摘With the development of vehicle-to-vehicle(V2V)communication,it is possible to share information among multiple vehicles.However,the existing research on automated lane changes concentrates only on the single-vehicle lane change with self-detective information.Cooperative lane changes are still a new area with more complicated scenarios and can improve safety and lane-change efficiency.Therefore,a multi-vehicle cooperative automated lane-change maneuver based on V2V communication for scenarios of eight vehicles on three lanes was proposed.In these scenarios,same-direction and intersectant-direction cooperative lane changes were defined.The vehicle that made the cooperative decision obtained the information of surrounding vehicles that were used to cooperatively plan the trajectories,which was called cooperative trajectory planning.The cooperative safety spacing model was proposed to guarantee and improve the safety of all vehicles,and it essentially developed constraints for the trajectory-planning task.Trajectory planning was treated as an optimization problem with the objective of maximizing safety,comfort,and lane-change efficiency under the constraints of vehicle dynamics and the aforementioned safety spacing model.Trajectory tracking based on a model predictive control method was designed to minimize tracking errors and control increments.Finally,to verify the validity of the proposed maneuver,an integrated simulation platform combining MATLAB/Simulink with CarSim was established.Moreover,a hardware-in-the-loop test bench was performed for further verification.The results indicated that the proposed multi-vehicle cooperative automated lane-change maneuver can achieve lane changes of multiple vehicles and increase lane-change efficiency while guaranteeing safety and comfort. | Yugong Luo Gang Yang Mingchang Xu Zhaobo Qin Keqiang Li | 2019 | Automotive Innovation2019,2,3: | 3 |
| 2 | Emergent computation: Virtual reality from disordered clapping to ordered clapping显示文摘Using the spontaneously synchronized clapping in a concert hall as a special case, we build a nonlinear emergent model to characterize the collective behaviors of the complex multi-agent systems. Based on this model, we develop an experimental platform for emergent computation, which only depends on the local interaction and reveals the uncertainty and diversity of emergent behaviors. By analyzing the data in the procedure of many hands clapping, we find that there exists an obvious critical region generated in the procedure from disorder to synchronization. Moreover, we propose a fundamental synchronous criterion as follows: If the coupling coefficients c1 and c2 satisfy the condition 0.02≤c2≤0.965c1+0.018, then the clapping can realize synchronization. | LI DeYi LIU Kun SUN Yan HAN MingChang | 2008 | Science in China(Series F)2008,51,5: | 2 |
| 3 | Difference between hemocyanin subunits from shrimp Penaeus japonicus in anti-WSSV defense显示文摘 | Lei Kaiyu Li Fang Zhang Mingchang | 2008 | Dev Comp Immunol2008,2,4: | 1 |
| 4 | RDX crystals with high sphericity prepared by resonance acoustic mixing assisted solvent etching technology显示文摘In order to obtain high-quality spherical RDX crystal particles,the RDX crystals were suspended in a mixed solvent of cyclohexanone and cyclohexane,subsequently a solvent etching study was carried out under the action of vibration/acoustic flow coupled flow field,which generated by resonance acoustic mixing.The effects of solvent ratio,temperature,acceleration and experiment time on morphology as well as particle size of RDX crystals were studied.Not only were the morphology,particle size distribution and crystal form of RDX crystals determined,but also the thermal decomposition performance and mechanical sensitivity of spherical RDX were examined and discussed.Results indicated that under the process of solvent/non-solvent volume ratio at 1:2,temperature of 40℃,acceleration of 40 g and experiment time of 4 h,α-type RDX crystal with sphericity of 0.92 can be obtained.Furthermore,the median particle size(D_(50))of spherical RDX crystals is 215.8 μm with a unimodal particle size distribution(size span 1.34).For one thing,the thermal decomposition peak temperature of spherical RDX is about 2.5℃ higher than that of raw RDX,and apparent activation energy reaches 444.68 kJ/mol.For another thing,impact sensitivity and friction sensitivity of spherical RDX are 18.18% and 33.33% lower than that of raw RDX,respectively.It demonstrates that safety of spherical RDX under thermal,impact and friction stimuli has been improved. | Dongjie Liao Qian Liu Chunyan Li Ning Liu Mingchang Wang Chongwei An | 2023 | Defence Technology(防务技术)2023,28,10: | 1 |
| 5 | Difference between hemocyanin subunits from shrimp Penaeus ja- ponicus in anti-WSSV defense显示文摘 | LEI Kaiyun LI Fang ZHANG Mingchang | 2008 | Dev Comp Immunol2008,2,4: | 1 |
| 6 | Genetic modification of miR-34a enhances efficacy of transplanted human dental pulp stem cells after ischemic stroke显示文摘Human dental pulp stem cells(hDPSCs) promote recovery after ischemic stro ke;however,the therapeutic efficacy is limited by the poor survival of transplanted cells.For in vitro expe riments in the present study,we used oxygen-glucose deprivation/reoxygenation in hDPSCs to mimic cell damage induced by ischemia/reperfusion.We found that miRNA-34a-5p(miR-34a) was elevated under oxygen-glucose deprivation/reoxygenation conditions in hDPSCs.Inhibition of miR-34a facilitated the prolife ration and antioxidant capacity and reduced the apoptosis of hDPSCs.Moreove r,dual-luciferase reporter gene assay showed WNT1and SIRT1 as the targets of miR-34a.In miR-34a knockdown cell lines,WNT1 suppression reduced cell prolife ration,and SIRT1 suppression decreased the antioxidant capacity.Togethe r,these results indicated that miR-34a regulates cell prolife ration and antioxidant stress via targeting WNT1 and SIRT1,respectively.For in vivo expe riments,we injected genetically modified hDPSCs(anti34a-hDPSCs) into the brains of mice.We found that anti34a-hDPSCs significantly inhibited apoptosis,reduced cerebral edema and cerebral infarct volume,and improved motor function in mice.This study provides new insights into the molecular mechanism of the cell prolife ration and antioxidant capacity of hDPSCs,and suggests a potential gene that can be targeted to improve the survival rate and efficacy of transplanted hDPSCs in brain after ischemic stroke. | Jianfeng Wang Peibang He Qi Tian Yu Luo Yan He Chengli Liu Pian Gong Yujia Guo Qingsong Ye Mingchang Li | 2023 | Neural Regeneration Research2023,18,9: | 1 |
| 7 | The Study on the tribological properties of fiber-reinforce PBT 显示文摘 | Jeng Mingchang Fung Chinping Li Tsechang | 2002 | Wear2002,252,: | 1 |
| 8 | Spherical natural graphite coated by a thick layer of carbonaceous mesophase for use as an anode material in lithium ion bat teries显示文摘 | Li Hui Wu Mingchang Wan Chuanyun | 2009 | Journal of Applied Electrochemistry2009,39,7: | 1 |
| 9 | Literature analysis of Dendrolimus disasters based on remote sensing monitoring显示文摘Due to global climate change,Dendrolimus pests and diseases seriously threaten the protec-tion of forestry plants and the safety of crops all over the world.This paper aims to discuss the research results and frontier progress of Dendrolimus disasters based on remote sensing monitoring,trying to find the occurrence characteristics of pests.In this paper,bibliometric methods and CiteSpace knowledge graphs were used to analyze the publication trend,highly cited documents,key research institutions,and high-frequency keywords of the extracted documents in the Web of Science(WOS)database.The following conclusions are drawn:(1)The amount of research in WOS is on the rise,but it has declined in recent years.The countries with strong influence in national cooperation are mainly the United States and China.(2)The United States Department of Agriculture-Agricultural Research Service(USDA ARS)and the Chinese Academy of Sciences have published a lot.This paper reviewed the research progress of high-frequency institutions.(3)The key research topics focus on remote sensing,agriculture,and environmental sciences.Besides,the research hotspots include remote sensing monitoring,climate change,spectral reflectance,vegetation index,and precision agriculture.Finally,we put forward the current challenges and development trends of remote sensing pest monitoring.This paper can provide a reference for the research on remote sensing monitoring of Dendrolimus disasters in the future. | WANG Mingchang ZHOU Yuyang LI Mingjie JI Xue LIU Ziwei | 2022 | Global Geology2022,25,1: | 0 |
| 10 | Evolutionary Game-theoretic Modeling of Massive Distributed Renewable Energy Deployment Towards Low-carbon Distribution Networks显示文摘This paper proposes an evolutionary game-theoretic model of massive distributed renewable energy deployment in order to shed light on the self-organization sustainable developments of renewable energies in distribution networks towards low-carbon targets. Since neighboring buses can interact in terms of energy exchanges, the return matrices of individual buses in the evolutionary game are established based on profiles of loads and renewable energy generation. More specifically, an evolutionary strategy is proposed based on the return matrices for individual buses to determine whether or not to deploy renewable energies in the next round of the game. Then, a dynamic model is derived for analyzing the renewable energy penetration rate in the distribution network throughout the multi-round evolutionary game. In theory, this model can reveal the self-organization process of renewable energy deployment in the distribution network. With this model, the distribution network operator would be aided in designing the incentives for buses deploying renewable energies toward a pre-defined low-carbon target. Numerical results on an actual 141-bus system and a synthetic 2000-bus system have demonstrated the validity and efficiency of the proposed model. | Xuanyi Xiao Jianbing Yin Lin Chen Mingchang Wang Yi Zhao Zhiyi Li | 2023 | Journal of Modern Power Systems and Clean Energy2023,11,5: | 0 |
| 11 | Red light-driven generation of reactive oxygen species for the targeted oxidation of glioma cells and thiols over covalent organic framework显示文摘Reactive oxygen species(RoS)are essential for biological processes like cell signaling and chemical processes like organic oxidation.Moreover,the sufficient generation of RoS plays a significant role in targeted tumor treatments or oxidation of organics.Herein,a hydrazone-linked porphyrin covalent organic framework(Por-DETH-COF)is developed for red light-induced generation of ROS like singlet oxygen(^(1)O_(2))or superoxide(O_(2)·^(-))to undertake different but targeted oxidations.First,^(1)O_(2)is adopted in photodynamic therapy(PDT)for the oxidation of glioma cells.The PDT efficiency of Por-DETH-COF on the apoptosis of glioma cells is explored through flow cytometry and western blot assay.The apoptosis rate of glioma cells significantly increases over Por-DETH-COF under 660nm red light illumination,suggestive of the potency of^(1)O_(2).Second,O_(2)^(·-)is employed for the targeted oxidation of thiols.A series of thiols could be efficiently oxidized to corresponding disulfides over Por-DETH-COF under 660 nm red light illumination,indicative of the significance of O_(2)^(·-).This work highlights the potential of covalent organic frameworks in generating Ros for precise medical applications of complex chemical environments. | Heng Wei Xia Li Fengwei Huang Shujuan Wu Huimin Ding Qianxue Chen Mingchang Li Xianjun Lang | 2023 | Chinese Chemical Letters2023,34,12: | 0 |
| 12 | MSC based gene delivery methods and strategies improve the therapeutic efficacy of neurological diseases显示文摘Mesenchymal stem cells(MSCs)are promising seed cells for neural regeneration therapy owing to their plasticity and accessibility.They possess several inherent characteristics advantageous for the transplantation-based treatment of neurological disorders,including neural differentiation,immunosuppression,neurotrophy,and safety.However,the therapeutic efficacy of MSCs alone remains unsatisfactory in most cases.To improve some of their abilities,many studies have employed genetic engineering to transfer key genes into MSCs.Both viral and nonviral methods can be used to overexpress therapeutic proteins that complement the inherent properties.However,to date,different modes of gene transfer have specific drawbacks and advantages.In addition,MSCs can be functionalized through targeted gene modification to facilitate neural repair by promoting neural differentiation,enhancing neurotrophic and neuroprotective functions,and increasing survival and homing abilities.The methods of gene transfer and selection of delivered genes still need to be optimized for improved therapeutic and targeting efficacies while minimizing the loss of MSC function.In this review,we focus on gene transport technologies for engineering MSCs and the application of strategies for selecting optimal delivery genes.Further,we describe the prospects and challenges of their application in animal models of different neurological lesions to broaden treatment alternatives for neurological diseases. | Heng Zhou Yan He Wei Xiong Shuili Jing Xingxiang Duan Zhiyun Huang Gurek SNahal Youjian Peng Mingchang Li Yaoqi Zhu Qingsong Ye | 2023 | Bioactive Materials2023,,5: | 0 |
| 13 | Evaluation and Driving Force Analysis of Cultivated Land Quality in Black Soil Region of Northeast China显示文摘Cultivated land is an important natural resource to ensure food,ecological and economic security.The cultivated land quality evaluation(CQE)is greatly significant for protecting and managing cultivated land.In this study,320 counties in the black soil region of Northeast China(BSRNC)represent the research units used to construct the CQE system measuring the soil properties(SP),cultivated land productivity(CLP),ecological environment(EE)and social economy(SE).The total of 19 factors were selected to calculate the integrated fertility index(IFI)and divided into grades.Simultaneously,we used the coupling coordination degree model to comprehensively analyze the spatial pattern of the cultivated land quality(CLQ)in the BSRNC,and use the structural equation model(SEM)to analyze the driving mechanism.The results show the following:1)The CLQ of 262 counties in the BSRNC is in a state of coupling and coordination,and the coupling and coordination degree presents a spatial distribution pattern of‘high in the southwest and northeast,low in the northwest and southeast’.The coordinated development degree of 271 counties is between 0.4 and 0.6,which is in a transitional state between coordination and disorder.2)The CLQ in the BSRNC is generally good,with an average grade of 3.High-quality cultivated land accounts for 58.45%of all counties,middle-and upper-quality cultivated land accounts for 27.05%,and poor-quality cultivated land accounts for 14.49%.3)The SEM analysis shows that the SP,CLP,EE,and SE all influence the CLQ.Among them,the SP has the largest driving force on the CLQ,while the SE has the smallest driving force on it.The results confirm that the main factors affecting the evaluation results are crop productivity level,normalized difference vegetation index,ratio vegetation index,difference vegetation index,and organic carbon content.When implementing protection measures in counties with a low CLQ,considering a balanced coordination of multiple systems and reasonably controlling the quality degradation are important.This study provides the current situation and driving factors of the CLQ in the BSRNC and will play an important role in black soil governance and utilization. | WANG Mingchang LIU Xingnan LIU Ziwei WANG Fengyan LI Xiaoyan HOU Guanglei ZHAO Shijun | 2023 | Chinese Geographical Science2023,33,4: | 0 |
| 14 | The Reform of Elastic-plastic Mechanics Teaching for Petroleum Engineering Related Majors显示文摘“Elastic-plastic Mechanics”is an important course for undergraduates and postgraduates of general engineering majors.However,the theoretical derivation of equations is complex,and the connection with engineering practice is inadequate.Therefore,teaching becomes difficult and boring for a number of students.Firstly,this paper introduces the importance of Elastic-plastic Mechanics for petroleum engineering related majors.Based on the recent teaching experience,the teaching reform of Elastic-plastic Mechanics course is carried out focusing on teaching method and learning content,and a discussion teaching mode based on students’independent discussion and engineering cases is formed.Remarkable results have been achieved in improving students’learning efficiency and classroom teaching effect.Furthermore,students’comprehensive ability of independent innovation and practice is enhanced. | Yanfei Chen Tongjing Xia Ye Zhang Lulu Li Mingchang He Hong Zhang | 2020 | Review of Educational Theory2020,3,4: | 0 |
| 15 | Classification of vegetative types in Changbai Mountain based on optical and microwave remote sensing data显示文摘Highly accurate vegetative type distribution information is of great significance for forestry resource monitoring and management.In order to improve the classification accuracy of forest types,Sentinel-1 and 2 data of Changbai Mountain protection development zone were selected,and combined with DEM to construct a multi-featured random forest type classification model incorporating fusing intensity,texture,spectral,vegetation index and topography information and using random forest Gini index(GI)for optimization.The overall accuracy of classification was 94.60%and the Kappa coefficient was 0.933.Comparing the classification results before and after feature optimization,it shows that feature optimization has a greater impact on the classification accuracy.Comparing the classification results of random forest,maximum likelihood method and CART decision tree under the same conditions,it shows that the random forest has a higher performance and can be applied to forestry research work such as forest resource survey and monitoring. | YANG Ying XU Mengxia LI Sheng WANG Mingchang LIU Ziwei ZHAO Shijun | 2023 | Global Geology2023,26,2: | 0 |
| 16 | Supramolecular assembly of Cp1-11 peptide and insulin for rapid-acting formulation显示文摘In order to improve the life quality of diabetic patients,it is very important to develop rapid-acting insulin formulations that can mimic the physiological meal-time secretion profile of insulin in healthy people.Although several insulin analogues have been designed to provide postprandial glycemic control,still there are some serious disadvantages.A supramolecular strategy is presented here to inhibit insulin aggregation and improve its bioactivity by using Cp1-11 peptide.As a fragment of C-peptide in proinsulin,Cp1-11 peptide was found to influence insulin oligomerization by supramolecular interactions.This work demonstrates that the Cp1-11 peptide can interact with oligomeric insulin and facilitate its disaggregation into the physiologically active monomeric form.Computer simulation indicates that Cp1-11 can insert into the space between the C-terminal tail and the N-terminal helix of the B-chain of insulin,causing dissociation of the insulin dimer.The supramolecular assembly of Cp1-11 and insulin can improve the bioavailability and therapeutic effect of insulin on the control of in vivo blood glucose levels.These results suggest that Cp1-11 peptide can modulate the intermolecular interaction of aggregated insulin and prevent the transition from monomeric to multimeric states,and shows great potential for the development of an effective rapid-acting strategy to treat diabetes. | Weigang Wang Sheyu Li Zhouxiang Zhao Anna Zhou Yanpeng Liu Yantao Chen Mingchang Lin Guosong Chen Chunmei Ding Jianshu Li | 2017 | Journal of Bioresources and Bioproducts2017,2,3: | 0 |
| 17 | Ferroptosis:a potential therapeutic target for stroke显示文摘Ferroptosis is a form of regulated cell death characterized by massive iron accumulation and iron-dependent lipid peroxidation,differing from apoptosis,necroptosis,and autophagy in several aspects.Ferroptosis is regarded as a critical mechanism of a series of pathophysiological reactions after stroke because of iron overload caused by hemoglobin degradation and iron metabolism imbalance.In this review,we discuss ferroptosis-related metabolisms,important molecules directly or indirectly targeting iron metabolism and lipid peroxidation,and transcriptional regulation of ferroptosis,revealing the role of ferroptosis in the progression of stroke.We present updated progress in the intervention of ferroptosis as therapeutic strategies for stroke in vivo and in vitro and summarize the effects of ferroptosis inhibitors on stroke.Our review facilitates further understanding of ferroptosis pathogenesis in stroke,proposes new targets for the treatment of stroke,and suggests that more efforts should be made to investigate the mechanism of ferroptosis in stroke. | Chengli Liu Guijun Wang Wenrui Han Qi Tian Mingchang Li | 2024 | Neural Regeneration Research2024,19,5: | 0 |
| 18 | Simulation and analysis for anthropogenic heat release显示文摘Heat balance of urban ecosystem is a key point for the study of urban climate and micro-climate pattern and its change mechanism. Urban heat island effect is becoming increasingly serious,which is mainly caused by the change of the earth's surface cover and the anthropogenic heat release. In this study,the simulation experiment for the anthropogenic heat release was designed according to the heat balance principle. A set of buildings of miniature city were used to constitute the residential area,U grooves were applied to simulate the single building,and the fluorescent lamps in the U groove were regarded as the heat sources of the anthropogenic heat release. The simulation experiment was launched with long-short wave sun photometer,sonic anemothermometer and heat flow gauge in the experiment site. Then the net solar radiation,sensible heat flux and heat flux into the ground were determined. The quantities of the anthropogenic heat release were calculated based on the heat balance principle,and were compared with the theoretical power consumption of the fluorescent lamps. The root mean square error( RMSE) of the simulation for the anthropogenic heat release reaches0. 078 W·m- 2,a comparatively high precision,which showes that the anthropogenic heat release can be accurately determined through the simulation experiments. This study provided a scientific method for the purpose of monitoring the anthropogenic heat release. | WANG Mingchang Matsushima Dai NIU Xuefeng LIANG Liheng LI Qiyuan | 2015 | Global Geology2015,18,1: | 0 |
| 19 | Condition-based Maintenance Optimization for Gamma Deteriorating Systems under Performance-based Contracting显示文摘With the further development of service-oriented,performance-based contracting(PBC)has been widely adopted in industry and manufacturing.However,maintenance optimization problems under PBC have not received enough attention.To further extend the scope of PBC’s application in the field of maintenance optimization,we investigate the condition-based maintenance(CBM)optimization for gamma deteriorating systems under PBC.Considering the repairable single-component system subject to the gamma degradation process,this paper proposes a CBM optimization model to maximize the profit and improve system performance at a relatively low cost under PBC.In the proposed CBM model,the first inspection interval has been considered in order to reduce the inspection frequency and the cost rate.Then,a particle swarm algorithm(PSO)and related solution procedure are presented to solve the multiple decision variables in our proposed model.In the end,a numerical example is provided so as to demonstrate the superiority of the presented model.By comparing the proposed policy with the conventional ones,the superiority of our proposed policy is proved,which can bring more profits to providers and improve performance.Sensitivity analysis is conducted in order to research the effect of corrective maintenance cost and time required for corrective maintenance on optimization policy.A comparative study is given to illustrate the necessity of distinguishing the first inspection interval or not. | Xi Zhu Liang Wen Juan Li Mingchang Song Qiwei Hu | 2023 | Chinese Journal of Mechanical Engineering2023,36,1: | 0 |
| 20 | Effects of Agaricus blazei Murill Polysaccharides on Leadinduced Disturbance of Morphology and ASIC1a and ASIC2b Gene Expression in Hippocampus of Rats显示文摘The present study was undertaken to investigate the effects of Agaricus blazei murill polysaccharides on morphology of hippocampus tissue and expression of ASIC1a and ASIC2b mRNA in lead-poisoning rats.Forty SD rats were divided into five groups:control group,lead group,experimental group 1,2,3.After 60d of treatments,hippocampus tissues were observed by HE staining and the expression levels of ASIC1a and ASIC2b mRNA were determined by the flouoreescent quantitative real-time polymerase chain reaction(FQRT-PCR).The results showed that after lead induction,the number of hippocampus neuron increased,cell gap increased,the chromatin was stained lightly;after administration of ABMP,the number of the hippocampus neuron increased as the dose of ABMP rose,cell gap decreased,the chromatin was stained darkly.The expression level of ASIC1a mRNA in hippocampus of rats in ABMP group decreased extremely significantly compared with that in the model group(P<0.01).Lead exposure and ABMP exhibited no significant effects on the expression level of ASIC2b mRNA.ABMP possesses a protective effect on nervous system of rats exposed to lead by combining with lead. | Xin LI Xiru LV Cuiping FENG Mingchang CHANG Hongyan CHENG Junlong MENG | 2014 | Agricultural Biotechnology2014,3,3: | 0 |