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| 1 | Diagenetic and Mineralization Age of the Hehuaping Tin-polymetallic Orefield,Hunan Province显示文摘摘要:Hehuaping 听存款是在地质的调查期间在最近的年里发现的大存款。发现的听存款在在在泥盆纪碳酸盐岩石(Qiziqiao 形成) 和沙岩(Tiaomajian 形成) 之间的 interstratifled 破裂地区开发的差错地区,而且存款包括不仅岩石改变类型存款。发现后者类型的听存款极大地在著名 Nanling polymetallic metallogenetic 区域充实听矿化作用类型并且可以为在这个区域听存款勘探向我们提供新潜在的取向。在 Nanling 区域形成听存款应该与 Yanshanian 有关而不是 Indosinian 花岗石的 magmatism,这通常被相信。系统的锆石 U-Pb 虾在这份报纸标明日期证明听矿化作用忍受了至少二个阶段。早阶段应该与 Wangxianling 花岗石的主要身体的侵入有关,它在 Indosinian 期间是 emplaced 有 diagenetic 和 224.0 | WEI Daofang BAO Zhengyu FU Jianming CAI Minghai | 2007 | Acta Geologica Sinica(English Edition)2007,81,2: | 23 |
| 2 | The MDM2-p53 pathway revisited显示文摘The p53 tumor suppressor is a key transcription factor regulating cellular pathways such as DNA repair, cell cycle, apoptosis, angiogenesis, and senescence. It acts as an important defense mechanism against cancer onset and progression, and is negatively regulated by interaction with the oncoprotein MDM2. In human cancers, the TP53 gene is frequently mutated or deleted, or the wild-type p53 function is inhibited by high levels of MDM2, leading to downregulation of tumor suppressive p53 pathways. Thus, the inhibition of MDM2-p53 interaction presents an appealing therapeutic strategy for the treatment of cancer. However, recent studies have revealed the MDM2-p53 interaction to be more complex involving multiple levels of regulation by numerous cellular proteins and epigenetic mechanisms, making it imperative to reexamine this intricate interplay from a holistic viewpoint. This review aims to highlight the multifaceted network of molecules regulating the MDM2-p53 axis to better understand the pathway and exploit it for anticancer therapy. | Subhasree Nag Jiangjiang Qin Kalkunte S.Srivenugopal Minghai Wang Ruiwen Zhang | 2013 | The Journal of Biomedical Research2013,27,4: | 13 |
| 3 | Polyphase orthogonal sequences design for opportunistic array radar via HGA显示文摘Opportunistic array radar(OAR) is a new generation radar system based on the stealth of the platform,which can improve the modern radar performance effectively.Designing the orthogonal code sets with low autocorrelation and cross-correlation is a key issue for OAR.This paper proposes a novel hybrid genetic algorithm(HGA) and designs the polyphase orthogonal code sets with low autocorrelation and cross-correlation properties,which can be used in the OAR system.The novel algorithm combines with simulated annealing(SA) and genetic algorithm(GA),adds in keeping best individuals and competition in small scope,and introduces grey correlation evaluation to evaluate fitness function. These avoid the premature convergence problem existed in GA and enhance the global searching capability.At last,the genetic results are optimized to obtain the best solution by using greedy algorithm.The simulation results show that the proposed algorithm is effective for the design of orthogonal phase signals used in OAR systems. | Shufeng Gong Weijun Long Hao Huang De Ben Minghai Pan | 2013 | Journal of Systems Engineering and Electronics2013,24,1: | 9 |
| 4 | Hardware-in-the-loop simulation technology of wide-band radar targets based on scattering center model显示文摘Hardware-in-the-loop(HWIL) simulation technology can verify and evaluate the radar by simulating the radio frequency environment in an anechoic chamber. The HWIL simulation technology of wide-band radar targets can accurately generate wide-band radar target echo which stands for the radar target scattering characteristics and pulse modulation of radar transmitting signal. This paper analyzes the wide-band radar target scattering properties first. Since the responses of target are composed of many separate scattering centers, the target scattering characteristic is restructured by scattering centers model. Based on the scattering centers model of wide-band radar target, the wide-band radar target echo modeling and the simulation method are discussed. The wide-band radar target echo is reconstructed in real-time by convoluting the transmitting signal to the target scattering parameters. Using the digital radio frequency memory(DRFM) system,the HWIL simulation of wide-band radar target echo with high accuracy can be actualized. A typical wide-band radar target simulation is taken to demonstrate the preferable simulation effect of the reconstruction method of wide-band radar target echo. Finally, the radar target time-domain echo and high-resolution range profile(HRRP) are given. The results show that the HWIL simulation gives a high-resolution range distribution of wide-band radar target scattering centers. | Huang Hao Pan Minghai Lu Zhijun | 2015 | Chinese Journal of Aeronautics2015,28,5: | 8 |
| 5 | Wettability and Bonding between Ni and Ti(C,N)with Multiple Carbide Additions显示文摘The wettability and bonding in Ni/Ti(C, N) systems with multiple carbide additions were studied by sessile drop technique and vacuum brazing technique, respectively. The phase characterizations of substrates and fracture surfaces were conducted by XRD. The microstructures at metal/ceramic interfaces and fracture surfaces were observed via SEM in back scattered mode and second electron mode, respectively. Furthermore, an X-ray energy-dispersive spectrometer (EDS) attached to SEM was used to study the elements diffusion in interfacial regions. The results reveal that diffusion and dissolution mechanism controlled reactive wetting takes place in the system in high temperature wetting. Results also show that the contact angles decrease with multiple carbide additions, and the effect of multiple carbide additions is stronger than that of single additions. The contact angle reaches the lowest value in the lowest TiC content case. The enhancement of the wettability is due to alloying procedure during high temperature wetting when metallic atoms diffuse into Ni phase, which decreases the interfacial energy of Ni/Ti(C, N) systems. The bonding results show that the interfacial bonding strength is higher than that of solid solutions, that makes most of the specimens fail in ceramics matrix. | Ning LIU, Minghai CHEN, Yudong XU, Jie ZHOU and Min SHIDepartment of Materials Science and Engineering, Hefei University of Technology, Hefei 230009, ChinaProf., Ph.D. | 2005 | Journal of Materials Science & Technology2005,21,1: | 6 |
| 6 | Preparation and Mechanical Properties of-SiC Nanoparticle Reinforced Aluminum Matrix Composite by a Multi-step Powder Metallurgy Process显示文摘β-SiC nanoparticle reinforced Al matrix(nano-SiCp/Al) composite was prepared by a multi- step powder metallurgy strategy including presureless sintering, hot compacting process and hot extrusion. The microstructures of the as-prepared composites were observed by scanning electronic microscopy(SEM), and the mechanical properties were characterized by tensile strength measurement and Brinell hardness test. The experimental results revealed that the tensile strength of the composite with the addition of 5wt%-SiC nanoprticles could be increased to 215 MPa, increasing by 110% compared with pure Al matrix. Comparative experiments reflected that the-SiC nanoprticles showed significant reinforcement effect than traditional-SiC micro-sized particles. The preparation process and sintering procedure were investigated to develop a cost effective preparation strategy to fabricate nano-SiCp/Al composite. | WANG Linong WU Hao WU Xingping CHEN Minghai LIU Ning | 2013 | Journal of Wuhan University of Technology(Materials Science)2013,28,6: | 5 |
| 7 | Radiative Transition Probability of the Eu^3+ Ion in Polymer Optical Fibre显示文摘An Eu-chelate-doped step-index polymer optical fibre(POF) is fabricated.Based on Judd-Ofelt(J-O) theory,the J-O parmeters are calculated to be Ω2=16.93×10^-20cm^2,Ω4=1.36×10^-20cm^2,Ω6=6.75×10^-20cm^2 form the emission spectrum of Eu(DBM)s Phen-doped polymethyl methacrylate(PMMA).The J-O parameters have been used to calculate the total radiavtive transition rate(555.78s^-1) and radiative lifetime(1799μs) of the ^5Do exciting state.The stimulated emission cross-sections σij and the fluorescence branch ratios β for the ^5Do→^7Fj'''''''' transitions are also evaluated.Analysis reveals that Eu(DBM)3 Phen-doped PMMA is promising for use in rare-earth-doped polymer optical fibre devices. | ZHENGZhi-Qiang LANGHao MINGHai ZHANGQi-Jin CHENBiao SUNXiao-Hong XIEJian-Ping | 2003 | Chinese Physics Letters2003,20,5: | 5 |
| 8 | Does top executives' US experience matter? Evidence from US-listed Chinese firms显示文摘Foreign firms face enormous obstacles in attracting investors and analysts when issuing securities in the United States.We use US-listed Chinese firms as our research sample and find that firms that hire top executives(i.e.,Chief Executive Officer[CEO]or Chief Financial Officer[CFO]) with work experience in the US or educational qualifications from the US attract more US institutional investors and analysts.Further,we find that CFOs' US experience dominates the results.Corroborating our results,we further find that firms with US-experienced CFOs are more likely to hold conference calls and voluntarily issue management forecasts,which suggests that CFOs with a US background are better at communicating with US investors and analysts and acting in alignment with US norms compared with Chinese CFOs.Collectively,our results suggest that hiring a CFO with a US background could facilitate cross-listed foreign firms to lower US investors' and analysts' information disadvantage. | Jingjing Li Minghai Wei Bingxuan Lin | 2016 | China Journal of Accounting Research2016,,4: | 4 |
| 9 | Population and genetic diversity of Tibetan red deer based on fecal DNA显示文摘The Tibet Shannan Red Deer Nature Reserve is the center of the geographic distribution of Tibetan red deer. This paper presents the results of DNA analysis of 199 red deer fecal pellet groups collected during 2013 and 2014 during the green-plant period. We successfully extracted DNA from 87 DNA pellet groups and determined individual identification with 12 microsatellite loci. We evaluated the genetic diversity of the population and various population estimates with Capwire in R software. The87 successfully extracted pellet groups were from 50 individuals. In the population, the average number of alleles was 7.58 ± 0.18, the average effective number of alleles was 4.58 ± 0.15, and average polymorphism information content was 0.67 ± 0.01. Among the 12 loci,only T123 was moderately polymorphic; the other 11 loci were highly polymorphic. Expected heterozygosity ranged from 0.45 to 0.91, with an average of 0.72 ± 0.01, and average observed heterozygosity was 0.52 ± 0.11.Although Tibetan red deer remains endangered, the high genetic diversity indicates that this population has a good chance of recovery. This study provided insight that could be used by the local forestry department to develop programs to protect Tibetan red deer. | Hejiao Hu Bo Xing Miao Yang Hamenya Mpemba Zhonghai Lv Minghai Zhang | 2018 | Journal of Forestry Research2018,29,1: | 4 |
| 10 | Thermal Performance and Mechanics Characteristic for Double Layer Microchannel Heat Sink显示文摘Double layer micro-channel heat sink(DLMCHS) has been widely used in various electronic devices; however, the existence of the nonuniform thermal strain distribution in actual operation has adverse effect on the overall stability. In this paper, two optimized designs of DLMCHS with cutting baffles on top and bottom layers are presented based on the traditional DLMCHS. The heat transfer and thermal stress performance are numerically analyzed and compared with the traditional DLMCHS. The results indicate that cutting baffles of micro-channels remarkably improves heat transfer and thermal stress performance. The optimized design with cutting baffles on the bottom layer decreases thermal strain but deteriorates heat transfer performance. The model with cutting baffles on the top layer has better combined thermal strain and heat transfer performance, which reduces thermal strain by about 1.5 times and enhances heat transfer by about 26.5%. For the design with cutting baffles on the top board, adding metal foam in the inlet collector can decrease the total minimum thermal strain by 51.4% and maximum temperature by 1.4 K, and increase the Nusselt number by 15%. These results indicate that DLMCHS with cutting baffles on the top layer has great potential for thermal managements on electronic devices with high power density. | XU Yupeng GONG Liang LI Yongtong BAI Zhang XU Minghai | 2019 | Journal of Thermal Science2019,28,2: | 2 |
| 11 | β-Elemene-loaded polymeric micelles intensify anti-carcinoma efficacy and alleviate side effects显示文摘β-Elemene is a volatile oil used for the treatment of cancer,but poor solubility,low bioavailability,and various adverse reactions limit its application.For amelio rating risks of the venous toxicity ofβ-elemene,intravenously injectable micelle ofβ-elemene was prepared using the thin-film hydration method.The results pointed out the micelles were uniformly spherical with about 20.96±0.1966 nm in average diameter and exhibited high entrapment efficiency(99.02%±0.88%).As revealed by drug release studies in vitro,β-elemene micelles had sustained drug release.Compared with freeβ-elemene,the micelles increased the drug cellular uptake and enhanced the anti-tumor effect in vitro through retarding cell cycle and inducing apoptosis.Meanwhile,the elevated se rum stability o fβ-elemene micelles implied less drug leakage and reduced toxicity.The wound healing and tube formation assay in vitro demonstrated the anti-metastasis and anti-angiogenesis effects ofβ-elemene micelles.Moreover,the pharmacokinetics study showed the AUC and T1/2 ofβ-elemene in micelle group were 1.79 and 1.62 times of that in free fi-elemene group,suggesting the circulation time ofβ-elemene in the blood had been prolonged.In addition,β-elemene micelles showed a favorable antitumor response compared with theβ-elemene solution on C26 colon cance r-bearing mice model.Local irritation study investigated in rabbits indicated that theβ-elemene micelles strikingly mitigated the irritation to the injection sites compared with freeβ-elemene.These results proved that the micelle could be a good candidate as an auspicious drug delivery system ofβ-elemene for the prospective clinical treatment of carcinoma. | Qiaoqiao Hu Lan Bai Zejiang Zhu Zhengying Su Peng Bai Minghai Tang Caixia Dou Junfeng Yan Rongsheng Tong Wuyu Zhang Lijuan Chen Lulu Cai | 2020 | Chinese Chemical Letters2020,31,3: | 2 |
| 12 | In-situ emb e dding zeolitic imidazolate framework derived Co–N–C bifunctional catalysts in carbon nanotube networks for flexible Zn–air batteries显示文摘Recently, the development of high-performance bifunctional oxygen catalysts integrated with flexible conductive scaffolds f or rechargeable metal-air batteries has attracted considerable interest, driving by fastgrowing wearable electronics. Herein, we report a flexible bifunctional oxygen catalyst thin film consisting of Co–N–C bifunctional catalysts embedding in carbon nanotube(CNT) networks. The catalyst is readily prepared by pyrolysis of cobalt-based zeolitic imidazolate frameworks(ZIF-67) that are in-situ synthesized in CNT networks. Such catalyst film demonstrates very high catalytic activities for oxygen reduction(onset potential: 0.91 V, and half-wave potential: 0.87 V vs. RHE) and oxygen evolution(10 m Acm^-2 at 1.58 V) reactions, high methanol tolerance property, and long-term stability(97% current retention). Moreover, our integrated catalyst film shows very good structure flexibility and robustness. Based on the obtained film air electrodes, flexible Zn–air batteries demonstrate low charging and discharging overpotentials(0.82 V at 1 m A cm^-1) and excellent structure stability in the bending tests. These results indicate that presently reported catalyst films are potential air electrodes for flexible metal–air batteries. | Bo Lv Sha Zeng Wei Yang Jian Qiao Chao Zhang Chengfeng Zhu Minghai Chen Jiangtao Di Qingwen Li | 2019 | Journal of Energy Chemistry2019,28,11: | 2 |
| 13 | Research and Application on Web Information Retrieval Based on Improved FP-Growth Algorithm显示文摘A kind of single linked lists named aggregative chain is introduced to the algorithm, thus improving the architecture of FP tree. The new FP tree is a one-way tree and only the pointers that point its parent at each node are kept. Route information of different nodes in a same item are compressed into aggregative chains so that the frequent patterns will be produced in aggregative chains without generating node links and conditional pattern bases. An example of | JIAO Minghai YAN Ping JIANG Huiyan | 2006 | Wuhan University Journal of Natural Sciences2006,11,5: | 2 |
| 14 | Impacts of space-time-frequency synchronization errors onwide-band target echo characteristics of bistatic/multistatic radar显示文摘Bistatic/multistatic radar has great potential advantages over its monostatic counterpart. However, the separation of a transmitter and a receiver leads to difficulties in locating the target position accurately and guaranteeing space-timefrequency synchronization of the transmitter and the receiver.The error model of space-time-frequency synchronization in a motion platform of bistatic/multistatic radar is studied. The relationship between the space synchronization error and the transmitter platform position, receiver platform position, moving state, and beam pointing error, is analyzed. The effect of space synchronization error on target echo power is studied. The target scattering characteristics are restructured by many separate scattering centers of the target in high frequency regions. Based on the scattering centers model of the radar target, this radar target echo model and the simulation method are discussed. The algorithm of bistatic/multistatic radar target echo accurately reflects the scattering characteristics of the radar target, pulse modulation speciality of radar transmitting signals, and spacetime-frequency synchronization error characteristics between the transmitter station and the receiver station. The simulation of bistatic radar is completed in computer, and the results of the simulation validate the feasibility of the method. | Minghai Pan Qinghua Han Shufeng Gong Weijun Long Haitao Wei | 2016 | Journal of Systems Engineering and Electronics2016,27,3: | 2 |
| 15 | The nutritional composition and digestion of plants foraged by red deer(Cervus elaphus xanthopygus) in northeast China显示文摘We studied species of plants foraged by red deer in the Muling forest region of northeastern China during January 2014 and 2015. We focused on nutritional composition, energy content, and the digestibility of these plants. Crude protein content varied by plant species.Average crude protein content was 7.5 ± 1.7% of dry matter, ranging from 4.5 to 10.3%. Crude lipid content did not vary by species and averaged 7 ± 1.5%(range5.4–9.8%). Non-fiber carbohydrate(NFC) and neutral detergent fiber(NDF) content varied broadly with average values being 20.1 ± 4.8%(range 13.5–28.8%) and64.7 ± 5.9%(range 53.5–71.8%), respectively. Energy content ranged from 16.7 to 19.7 k J/g. Average dry matter digestibility(DMD) was 46.1 ± 4.8%, with a range from38.7 to 54.6%. Only three plants, Saussurea manshurica,Aralia elata and Equisetum hyemale exhibited DMD [ 50%. NFC content explained most of the variation in energy content(r = 0.451). In contrast, energy content was inversely related to NDF(r =-0.443). There was no correlation between crude protein, crude lipid, and energy content(r_(protein)= 0.004, r_(lipid)=-0.190). S. manshurica,A. elata and E. hyemale had higher NFC and lower NDF content. Thus, these species offered the greatest nutritional value for wintering red deer in the study area. Along with high CP and NFC content, Taxus cuspidate also had high lignin content, and was thus, considered a good forage species for red deer. | Yuan Feng Yanze Yu Linqiang Zhong Weiqi Zhang Minghai Zhang | 2018 | Journal of Forestry Research2018,29,3: | 2 |
| 16 | Time resource management of OAR based on fuzzy logic priority for multiple target tracking显示文摘For coping with the multiple target tracking in the presence of complex time-varying environments and unknown target information, a time resource management scheme based on chance-constraint programming(CCP) employing fuzzy logic priority is proposed for opportunistic array radar(OAR). In this scheme,the total beam illuminating time is minimized by effective time resource allocation so that the desired tracking performance is achieved. Meanwhile, owing to the randomness of radar cross section(RCS), the CCP is used to balance tracking accuracy and time resource conditioned on the specified confidence level. The adaptive fuzzy logic prioritization, imitating the human decision-making process for ranking radar targets, can realize the full potential of radar. The Bayesian Crame ′r-Rao lower bound(BCRLB) provides us with a low bound of localization estimation root-mean-square error(RMSE), and equally important, it can be calculated predictively. Consequently, it is employed as an optimization criterion for the time resource allocation scheme. The stochastic simulation is integrated into the genetic algorithm(GA) to compose a hybrid intelligent optimization algorithm to solve the CCP optimization problem. The simulation results show that the time resource is saved strikingly and the radar performance is also improved. | HAN Qinghua PAN Minghai ZHANG Wucai LIANG Zhiheng | 2018 | Journal of Systems Engineering and Electronics2018,29,4: | 2 |
| 17 | Generation of murine CTL by a hepatitis B virus-specific peptide and evaluation of the adjuvant effect of heat shock protein glyeoprotein 96 and its terminal fragments显示文摘 | Li Hongtao Zhou Minghai Han Jinle | 2005 | J Immunol2005,174,1: | 1 |
| 18 | Kinetics of p -nitro-phenol adsorption by layered double oxides during its hydration 显示文摘 | Peng Shuchuan Ma Minghai Jin Song | 2009 | Water Environment Research2009,81,1: | 1 |
| 19 | Finite element analysis of moving trestle of CNC machine tool显示文摘 | SUN Lei WANG Minghai LI Xiaopeng | 2011 | Advanced Materials Research2011,,: | 1 |
| 20 | Synthesis and characterization of cadmium selenide nanorods via surfactant-assisted hydrothermal method显示文摘 | Gao Lian | 2005 | J Am Ceram Soc2005,8,6: | 1 |