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| 1 | In-situ observation for formation and dissociation of carbon dioxide hydrate in porous media by magnetic resonance imaging显示文摘The study of formation and dissociation of CO 2 hydrate in porous media was characterized by magnetic resonance imaging (MRI) system in in situ conditions. This work simulated porous media by using glass beads of uniform size. The growth and dissociation habit of CO2 hydrate was observed under different temperature and pressure conditions. The induction time and the hydrate saturation during the growth and dissociation process in different sizes of porous media were obtained by using the MRI signal intensity. The results indicate that hydrate growth rate and the induction time are affected by the size of porous media, pressure, and degree of supercooling. There are three hydrate growth stages, i.e., initial growth stage, rapid growth stage and steady stage. In this study,the CO2 hydrate forms preferentially at the surface of vessel and then gradually grows inward. The hydrate tends to cement the glass beads together and occupies the pore gradually. As the hydrate decomposes gradually, the dissociation rate increases to the maximum and then decreases to zero. | CHENG ChuanXiao ZHAO JiaFei SONG YongChen ZHU ZiHao LIU WeiGuo ZHANG Yi YANG MingJun YU XiChong | 2013 | Science China Earth Sciences2013，56，4： | 5 |
| 2 | Lipid-dependent conformational dynamics underlie the functional versatility of T-cell receptor显示文摘T 房间 receptor-CD3 建筑群(TCR ) 是能基于 CD3 细胞质的领域的各种各样的生物化学的变化开始抗原特定的有免疫力的回答的一台万用的发信号机器,但是内在的结构的基础留下逃犯。这里,我们开发了生物物理的途径学习 CD3 细胞质的领域的 conformational 动力学(CD3 CD ) 。在单个分子的水平,我们发现那 CD3 CD 能与三个功能的主题的不同坦诚有多重 conformational 状态,即, ITAM, BRS 和 PRS。因为,这些符合构造被产生 CD3 CD 有异构的类脂化合物绑定性质因此有异构的动力学。实时房间的成像实验证明不同抗原刺激能稳定 CD3 在不同符合构造的 CD 。类脂化合物依赖者 conformational 动力学因此为 TCR 的万用的发信号性质提供结构的基础。 | Xingdong Guo Chengsong Yan Hua Li Wenmao Huan Xiaoshan Shi Min Huang Yingfang Wang Weiling Pan Mingjun Cai Lunyi Li Wei Wu Yibing Bai Chi Zhang Zhijun Liu Xinyan Wang Xiaohui F Zhang Chun Tang Hongda Wang Wanli Liu Bo Ouyang Catherine C Wong Yi Cao Chenqi Xu | 2017 | Cell Research2017，27，4： | 5 |
| 3 | Dissociation characteristics of methane hydrate using depressurization combined with thermal stimulation显示文摘Methane hydrate is considered as a potential energy source in the future due to its abundant reserves and high energy density.To investigate the influence of initial hydrate saturation,production pressure,and the temperature of thermal stimulation on gas production rate and cumulative gas production percentage,we conducted the methane hydrate dissociation experiments using depressurization,thermal stimulation and a combination of two methods in this study.It is found that when the gas production pressures are the same,the higher the hydrate initial saturation,the greater change in hydrate reservoir temperature.Therefore,it is easier to appear the phenomenon of icing and hydrate reformation when the hydrate saturation is higher.For example,the reservoir temperature dropped to below zero in depressurization process when the hydrate saturation was about 37%.However,the same phenomenon didn’t appear as the saturation was about 12%.This may be due to more free gas in the reservoir with hydrate saturated of 37%.We also find that the temperature variation of reservoir can be reduced effectively by combination of depressurization and thermal stimulation method.And the average gas production rate is highest with combined method in the experiments.When the pressure of gas production is 2 MPa,compared with depressurization,the average of gas production can increase 54%when the combined method is used.The efficiency of gas production is very low when thermal stimulation was used alone.When the temperature of thermal stimulation is 11℃,the average rate of gas production in the experiment of thermal stimulation is less than 1/3 of that in the experiment of the combined method. | Mingjun Yang Zhanquan Ma Yi Gao Lanlan Jiang | 2019 | Chinese Journal of Chemical Engineering2019，27，9： | 5 |
| 4 | Emerging roles for PlWl proteins in cancer显示文摘 | Yi Tan Lianyong Liu Mingan Liao Chaobao Zhang Shuanggang Hu Mei Zou Mingjun Gu Xiangqi Li | 2015 | Acta Biochimica et Biophysica Sinica2015，47，5： | 4 |
| 5 | Mussel-inspired multifunctional coating for bacterial infection prevention and osteogenic induction显示文摘Bacterial infection and osteogenic integration are the two main problems that cause severe complications after surgeries. In this study, the antibacterial and osteogenic properties were simultaneously introduced in biomaterials, where copper nanoparticles(Cu NPs) were generated by in situ reductions of Cu ions into a mussel-inspired hyperbranched polyglycerol(MI-h PG) coating via a simple dip-coating method.This hyperbranched polyglycerol with 10 % catechol groups’ modification presents excellent antifouling property, which could effectively reduce bacteria adhesion on the surface. In this work, polycaprolactone(PCL) electrospun fiber membrane was selected as the substrate, which is commonly used in biomedical implants in bone regeneration and cardiovascular stents because of its good biocompatibility and easy post-modification. The as-fabricated Cu NPs-incorporated PCL membrane [PCL-(MI-h PG)-Cu NPs]was confirmed with effective antibacterial performance via in vitro antibacterial tests against Staphylococcus aureus(S. aureus), Escherichia coli(E. coli), and multi-resistant E. coli. In addition, the in vitro results demonstrated that osteogenic property of PCL-(MI-h PG)-Cu NPs was realized by upregulating the osteoblast-related gene expressions and protein activity. This study shows that antibacterial and osteogenic properties can be balanced in a surface coating by introducing Cu NPs. | Mingjun Li Christoph Schlaich Jianguang Zhang Ievgen S.Donskyi Karin Schwibbert Frank Schreiber Yi Xi Jorg Radnik Tanja Schwerdtle Rainer Haag | 2021 | Journal of Materials Science & Technology2021，，9： | 1 |
| 6 | Reconstitution of Motor Proteins through Molecular Assembly显示文摘What is the most favorite and original chemistry developed in your research group?The most favorite and original chemistry developed in my research group is about the reconstitution of motor proteins in artificially designed and assembled units.It is based on the molecular assembly technique,but the method is different from the conventional approach. | Yi Jia Mingjun Xuan Xiyun Feng Li Duan Jieling Li Junbai Li | 2020 | Chinese Journal of Chemistry2020，38，2： | 1 |
| 7 | IGBT Temperature Field Monitoring Based on Reduced-order Model显示文摘With the rapid development of the world economy,IGBT has been widely used in motor drive and electric energy conversion.In order to timely detect the fatigue damage of IGBT,it is necessary to monitor the junction temperature of IGBT.In order to realize the fast calculation of IGBT junction temperature,a finite element method of IGBT temperature field reduction is proposed in this paper.Firstly,the finite element calculation process of IGBT temperature field is introduced and the linear equations of finite element calculation of temperature field are derived.Temperature field data of different working conditions are obtained by finite element simulation to form the sample space.Then the covariance matrix of the sample space is constructed,whose proper orthogonal decomposition and modal extraction are carried out.Reasonable basis vector space is selected to complete the low dimensional expression of temperature vector inside and outside the sample space.Finally,the reduced-order model of temperature field finite element is obtained and solved.The results of the reduced order model are compared with those of the finite element method,and the performance of the reduced-order model is evaluated from two aspects of accuracy and rapidity. | Ziyu Zhou Yi Su Xu Zhang Chengde Tong Ping Zheng Mingjun Zhu | 2023 | CES Transactions on Electrical Machines and Systems2023，7，2： | 0 |
| 8 | Integration of Excellent Chinese Traditional Culture into the Training and Education of Acupuncture and Massage Professionals显示文摘By reflecting on the current situation of the integration of excellent Chinese traditional culture into the training of acupuncture and massage professionals,this paper aims to carry out the research on the integration of excellent Chinese traditional culture into the training and education of acupuncture and massage.The specific implementation path includes early investigation and analysis,establishment of research objectives,formulation of teaching strategies,means and methods,empirical research on the process of teaching practice,teaching measurement and evaluation,and so on.Finally,it summarizes the connotation of the integration of excellent Chinese traditional culture into the training of acupuncture and massage professionals,in order to provide new ideas and methods for the integration of excellent Chinese traditional culture into the training and education of acupuncture and massage professionals. | Xiaochao GANG Mingjun LIU Shaotao CHEN Chongwen ZHONG Tianjiao GAO Yi TAN Dongmei ZHANG | 2023 | Medicinal Plant2023，14，2： | 0 |
| 9 | Rapid and mass manufacturing of soft hydrogel microstructures for cell patterns assisted by 3D printing显示文摘Micro-/nano-patterns on hydrogels are widely used in cell patterning.However,manufacturing molds with traditional lithography is time-consuming and expensive.In addition,the excessive demolding force can easily damage patterns since biocompatible hydrogels are ultra-soft or brittle.Here,we presented a novel method for rapid and mass fabrication of cell patterns.High-precision three-dimensional(3D)printing was used to manufacture a mold with a resolution of 2µm,and the gelatin-based hydrogel was cured by thermal–photo-crosslinking so that the low-concentration and low-substitutionrate hydrogel could be demolded successfully.We found that pre-cooling before illumination made gelatin-based hydrogels resilient due to the partial regain of triple-helix structures.With this method,arbitrarily customized hydrogel patterns with a feature size of 6–80µm can be fabricated stably and at low cost.When cardiomyocytes were seeded on ultra-soft hydrogels with parallel groove structures,a consistent and spontaneous beating with 216 beats per minute(BPM)could be observed,approaching the natural beating rate of rat hearts(300 BPM).Overall,this work provides a general scheme for manufacturing cell patterns which has great potential for cell ethology and tissue repair. | Chaofan He Xuechun Chen Yuan Sun Mingjun Xie Kang Yu Jing He Jinwei Lu Qing Gao Jing Nie Yi Wang Yong He | 2022 | Bio-Design and Manufacturing2022，5，4： | 0 |
| 10 | Solvent transport dynamics and its effect on evolution of mechanical properties of nitrocellulose(NC)-based propellants under hot-air drying process显示文摘Appropriate drying process with optimized controlling of drying parameters plays a vital role in the improvement of the quality and performance of propellant products.However,few research on solvent transport dynamics within NC-based propellants was reported,and its effect on the evolution of mechanical properties was not interpreted yet.This study is conducted to gain a comprehensive understanding of hot-air drying for NC-based propellants and clarify the effect of temperature on solvent transport behavior and further the change of mechanical properties during drying.The drying kinetic curves show the drying time required is decreased but the steady solvent content is increased and the drying rate is obviously increased with the increase of hot-air temperatures,indicating hot-air temperatures have a significant effect on drying kinetics.A modified drying model was established,and results show it is more appropriate to describe solvent transport behavior within NC-based propellants.Moreover,two linear equations were established to exhibit the relationship between solvent content and its effect on the change of tensile properties,and the decrease of residual solvent content causes an obvious increase of tensile strength and tensile modulus of propellant products,indicating its mechanical properties can be partly improved by adjustment of residual solvent content.The outcomes can be used to clarify solvent transport mechanisms and optimize drying process parameters of double-based gun propellants. | Enfa Fu Mingjun Yi Qianling Liu Zhenggang Xiao | 2024 | Defence Technology(防务技术)2024，32，2： | 0 |
| 11 | Self-accommodated defect structures modifying the growth of Laves phase显示文摘Laves phases,with the topologically close-packed structure and a chemical formula of Ab_(2),constitute the largest single class of intermetallics.Planar defects in Laves phases are widely investigated,especially for stacking behavior transformations through synchroshear.Here,we report the coexistence of C14,C36 and C15 structures in MgZn_2 precipitates by using atomic resolution scanning transmission electron microscopy,verifying the previously predicted Laves phase transformation sequence of C14→C36→C15 also applies to MgZn_2.One type of stacking fault couple in precipitates has been found to alone reduce the lattice mismatch with matrix,while some other stacking fault couples need to self-accommodate with irregular planar defects(rhombic units and flattened hexagonal units),or with five-fold symmetry structures to relieve the strain concentration.Precipitates thus grow towards an equiaxed or even round morphology,rather than the plate morphology as conventionally believed.Molecular dynamics calculations are performed to support our analysis.These findings reveal the principles governing the concurrent occurrence of various defects in laves structures,acting as an update of the widely accepted perception of random occurrence of defects during crystal growth. | Tong Yang Yi Kong Jiangbo Lu Zhenjun Zhang Mingjun Yang Ning Yan Kai Li Yong Du | 2021 | Journal of Materials Science & Technology2021，，3： | 0 |
| 12 | Effects of Tuina on Obesity-Induced Insulin Resistance and Cognitive Dysfunction显示文摘This paper discusses the mechanism of insulin resistance in obesity from the research progress of Chinese and Western medicine and its oxidative stress,inflammatory reaction and abnormal lipid metabolism in cognitive dysfunction.It also reviews the research progress of massage,one of the external treatment methods of traditional Chinese medicine,in the treatment of insulin resistance and cognitive dysfunction in obesity,in order to provide more new ideas and new ways for clinical diagnosis and treatment of insulin resistance and related cognitive dysfunction caused by obesity. | Mingjun LIU Xiaochao GANG Chongwen ZHONG Shaotao CHEN Yuxing TAI Yi TAN Likun ZHENG Zhengri CONG Sixian WANG Peizhe LI Qifan GUAN Yiduo LI | 2023 | Medicinal Plant2023，14，1： | 0 |
| 13 | Effect of Acupressure Therapy on Anti-inflammatory Mechanism in Obesity-induced IR Rats显示文摘[Objectives] To study the effect of 'acupressure therapy' on anti-inflammatory mechanism in obesity-induced IR rats. [Methods] 10 rats were randomly selected and fed with normal diet as blank group, and the remaining 30 rats were fed with high-fat diet for 8 weeks. The obesity-induced IR model was induced and divided into two groups: model group and acupressure group. The acupressure group was treated by 'acupressure therapy' three times a week for 6 weeks;the model group was taken 3 times at the same time every week, and the supine binding experiment lasted for 10 min for 6 weeks. Morphological observation was carried out before and after the experiment, mainly observing the general conditions and body weight. After the last intervention, the animals were killed and samples were collected. Western Blot method was used to detect the expression of TNF-α and IL-6 protein in adipose tissue of the three groups. [Results] Compared with the blank group, the expression of TNF-α and IL-6 protein in adipose tissue of the model group increased significantly ( P <0.01);compared with the model group, the expression of TNF-α and IL-6 protein in adipose tissue of the acupressure group decreased significantly ( P <0.01). [Conclusions] After intervening in the obesity-induced IR rats with acupressure method, the status of insulin resistance in obese rats was improved by inhibiting the expression of inflammatory factors. | Xiaochao GANG Mingjun LIU Tianjiao GAO Yuxing TAI Yi TAN Dongmei ZHANG Chongwen ZHONG Shaotao CHEN Rongsheng JIANG Zhengri CONG Likun ZHENG Peizhe LI | 2023 | Medicinal Plant2023，14，4： | 0 |
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