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| 1 | Super stable CsPbBr3@SiO2 tumor imaging reagent by stress-response encapsulation显示文摘Great photoelectric properties can herald the high potentials of CsPbBr3 nanocrystals(NCs)to function as the fluorescent probes for early tumor diagnosis.However,the intrinsic water vulnerability of CsPbBr3 NCs highly restricts their biomedical applications.To conquer this challenge,we herein introduce a nature inspired'stress-response'method to tightly encapsulate CsPbBr3 into SiO2 nano-shells that can dramatically improve the water stability of CsPbBr3@SiO2 nanoparticles for over 48 h.We further highlighted the advantageous features of CsPbBr3@SiO2 by using them as the fluorescent probes for CT26 tumor cell imaging with their high water stability,biocompatibility,and low cytotoxicity.Our work for the first time exhibited the potential of lead halide perovskite NCs for tumor diagnosis,and can highly anticipate the further in vivo biomedical applications that light up live cells. | Wentao Song Yiming Wang Bing Wang Yingfang Yao Wenguang Wang Jinhui Wu Qing Shen Wenjun Luo Zhigang Zou | 2020 | Nano Research2020，13，3： | 7 |
| 2 | Sintering of WC-Co powder with nanocrystalline WC by spark plasma sintering显示文摘A 92WC-8Co powder mixture with 33 nm WC grains was prepared by strengthening ball milling and was then sintered by spark plasma sintering (SPS) at 1000-1200°C for 5-18 min under 10-25 kN, respectively. Movement of the posi-tion of low punch shown shrinkage of the sintered body began above 800°C. The shrinkage slowly rose as the temperature rose from 800 to 1000°C and then quickly rose at above 1000°C and then gradually rose at above 1150°C. The densities of the samples increased with an increase in sintering temperature, rapidly below 1100°C, and then gradually above 1100°C. WC grains grow gradually with increasing sintering temperature. The powder was sintered to near full density at 1100°C for 5 min under 10 kN. The best result of the sample with 275 nm WC grains and no pores was obtained at 1150°C under 10 kN for 5 min. The research found the graphite die had a function of carburization, which could compensate the sintered body for the lack of carbon, and had the normal microstructure. | WANG Xingqing XIE Yingfang GUO Hailiang O.Van der Biest J.Vleugels | 2006 | Rare Metals2006，25，3： | 7 |
| 3 | The genome of Medicago polymorpha provides insights into its edibility and nutritional value as a vegetable and forage legume显示文摘Medicago polymorpha is a nutritious and palatable forage and vegetable plant that also fixes nitrogen.Here,we reveal the chromosome-scale genome sequence of M.polymorpha using an integrated approach including Illumina,PacBio and Hi-C technologies.We combined PacBio full-length RNA-seq,metabolomic analysis,structural anatomy analysis and related physiological indexes to elucidate the important agronomic traits of M.polymorpha for forage and vegetable usage.The assembled M.polymorpha genome consisted of 457.53Mb with a long scaffold N50 of 57.72Mb,and 92.92%(441.83Mb)of the assembly was assigned to seven pseudochromosomes.Comparative genomic analysis revealed that expansion and contraction of the photosynthesis and lignin biosynthetic gene families,respectively,led to enhancement of nutritious compounds and reduced lignin biosynthesis in M.polymorpha.In addition,we found that several positively selected nitrogen metabolism-related genes were responsible for crude protein biosynthesis.Notably,the metabolomic results revealed that a large number of flavonoids,vitamins,alkaloids,and terpenoids were enriched in M.polymorpha.These results imply that the decreased lignin content but relatively high nutrient content of M.polymorpha enhance its edibility and nutritional value as a forage and vegetable.Our genomic data provide a genetic basis that will accelerate functional genomic and breeding research on M.polymorpha as well as other Medicago and legume plants. | Jiawen Cui Zhaogeng Lu Tianyi Wang Gang Chen Salma Mostafa Hailong Ren Sian Liu Chunxiang Fu Li Wang Yingfang Zhu Jinkai Lu Xiang Chen Zhenwu Wei Biao Jin | 2021 | Horticulture Research2021，8，1： | 6 |
| 4 | Lipid-dependent conformational dynamics underlie the functional versatility of T-cell receptor显示文摘T 房间 receptor-CD3 建筑群(TCR ) 是能基于 CD3 细胞质的领域的各种各样的生物化学的变化开始抗原特定的有免疫力的回答的一台万用的发信号机器,但是内在的结构的基础留下逃犯。这里,我们开发了生物物理的途径学习 CD3 细胞质的领域的 conformational 动力学(CD3 CD ) 。在单个分子的水平,我们发现那 CD3 CD 能与三个功能的主题的不同坦诚有多重 conformational 状态,即, ITAM, BRS 和 PRS。因为,这些符合构造被产生 CD3 CD 有异构的类脂化合物绑定性质因此有异构的动力学。实时房间的成像实验证明不同抗原刺激能稳定 CD3 在不同符合构造的 CD 。类脂化合物依赖者 conformational 动力学因此为 TCR 的万用的发信号性质提供结构的基础。 | Xingdong Guo Chengsong Yan Hua Li Wenmao Huan Xiaoshan Shi Min Huang Yingfang Wang Weiling Pan Mingjun Cai Lunyi Li Wei Wu Yibing Bai Chi Zhang Zhijun Liu Xinyan Wang Xiaohui F Zhang Chun Tang Hongda Wang Wanli Liu Bo Ouyang Catherine C Wong Yi Cao Chenqi Xu | 2017 | Cell Research2017，27，4： | 5 |
| 5 | Crystal structure and nucleotide selectivity of human IFIT5/ISG58显示文摘 | Feng Feng LingminYuan Yao E Wang Christopher Crowley Zongyang Lv Jingjing Li Yingfang Liu Genhong Cheng Su Zeng Huanhuan Liang | 2013 | Cell Research2013，23，8： | 4 |
| 6 | Difficult and complicated oral ulceration:an expert consensus guideline for diagnosis显示文摘The complexity of oral ulcerations poses considerable diagnostic and therapeutic challenges to oral specialists.The expert consensus was conducted to summarize the diagnostic work-up for difficult and complicated oral ulcers,based on factors such as detailed clinical medical history inquiry,histopathological examination,and ulceration-related systemic diseases screening.Not only it can provide a standardized procedure of oral ulceration,but also it can improve the diagnostic efficiency,in order to avoid misdiagnosis and missed diagnosis. | Xin Zeng Xin Jin Liang Zhong Gang Zhou Ming Zhong Wenmei Wang Yuan Fan Qing Liu Xiangmin Qi Xiaobing Guan Zhimin Yan Xuemin Shen Yingfang Wu Lijie Fan Zhi Wang Yuan He Hongxia Dan Jiantang Yang Hui Wang Dongjuan Liu Hui Feng Kai Jiao Qianming Chen | 2022 | International Journal of Oral Science2022，14，2： | 2 |
| 7 | Surpassing electrocatalytic limit of earth-abundant Fe^(4+)embedded in N-doped graphene for(photo)electrocatalytic water oxidation显示文摘Developing highly active,cost-effective,and environmental friendly oxygen evolution reaction(OER)electrocatalysts facilitates various(photo)electrochemical processes.In this work,Fe3N nanoparticles encapsulated into N-doped graphene nanoshells(Fe_(3)N@NG)as OER electrocatalysts in alkaline media were reported.Both the experimental and theoretical comparison between Fe_(3) N@NG and Fe_(3)N/NG,specifically including in situ Mossbauer analyses,demonstrated that the NG nanoshells improved interfacial electron transfer process from Fe_(3)N to NG to form high-valence Fe^(4+)ions(Fe^(4+)@NG),thus modifying electronic properties of the outer NG shells and subsequently electron transfer from oxygen intermediate to NG nanoshells for OER catalytic process.Meanwhile,the NG nanoshells also protected Fe-based cores from forming OER inactive and insulated Fe_(2)O_(3),leading to high OER stability.As a result,the as-formed Fe^(4+)@NG shows one of the highest electrocatalytic efficiency among reported Fe-based OER electrocatalysts,which can as well highly improve the photoelectrochemical water oxidation when used as the cocatalysts for the Fe_(2)O_(3) nanoarray photoanode. | Wenjia Xue Feng Cheng Menglu Li Wenjian Hu Congping Wu Bing Wang Kuowei Liao ZhenTao Yu Yingfang Yao Wenjun Luo Zhigang Zou | 2021 | Journal of Energy Chemistry2021，30，3： | 2 |
| 8 | A new method for multi - focus im- age fusion using countourlet transform 显示文摘 | WANG Xin LI Yingfang | 2011 | IEEE Publication Year2011，，10： | 1 |
| 9 | The investigation of electrospun polymer nanofibers as a solid-phase extraction sorbent for the determination of trazodone in human plasma显示文摘 | Xuejun Kang Cao Pan Qian Xu Yingfang Yao Yian Wang Dongjin Qi Zhongze Gu | 2007 | Analytica Chimica Acta2007，，1： | 1 |
| 10 | In situ resource utilization of lunar soil for highly efficient extraterrestrial fuel and oxygen supply显示文摘Building up a lunar settlement is the ultimate aim of lunar exploitation.Yet,limited fuel and oxygen supplies restrict human survival on the Moon.Herein,we demonstrate the in situ resource utilization of lunar soil for extraterrestrial fuel and oxygen production,which may power up our solely natural satellite and supply respiratory gas.Specifically,the lunar soil is loaded with Cu species and employed for electro catalytic CO_(2)conversion,demonstrating significant production of methane.In addition,the selected component in lunar soil(i.e.MgSiO_(3))loaded with Cu can reach a CH_(4)F aradaic efficiency of 72.05% with a CH_(4)production rate of 0.8 mL/min at 600 mA/cm^(2).Simultaneously,an O_(2)production rate of 2.3 mL/min can be achieved.Furthermore,we demonstrate that our developed process starting from catalyst preparation to electrocatalytic CO_(2)conversion is so accessible that it can be operated in an unmmaned manner via a robotic system.Such a highly efficient extraterrestrial fuel and oxygen production system is expected to push forward the development of mankind’s civilization toward an extraterrestrial settlement. | Yuan Zhong Jingxiang Low Qing Zhu Yawen Jiang Xiwen Yu Xinyu Wang Fei Zhang Weiwei Shang Ran Long Yingfang Yao Wei Yao Jun Jiang Yi Luo Weihua Wang Jinlong Yang Zhigang Zou Yujie Xiong | 2023 | National Science Review2023，10，2： | 1 |
| 11 | A new approach for evaluating the resectability of pancreatic and periampullary neoplasms显示文摘 | Chi-hua Fang Wen Zhu Huaizhi Wang Nan Xiang Yingfang Fan Jian Yang Xiaojun Wang Shi zheng Zhong | 2012 | Pancreatology2012，，4： | 1 |
| 12 | Optical Design and Preparation of High Performance Mo/NiAlN/NiAlON/SiO_2 Solar Selective Absorbing Coating显示文摘A new solar selective absorbing coating of Mo/NiAlN/NiAlON/SiO_2 multilayer was prepared on stainless steel(SS) substrates by magnetron sputtering for solar thermal power applications. The optical constants and thickness of individual layers were simulated using the Scout software based on the experimentally measured reflectance and transmittance spectra of individual layers. The coating of Mo/NiAlN/NiAlON/SiO_2 with an ideal solar absorptance(α) of 0.945 in the solar spectrum range was designed via the optical constants of each layer in the Scout software. The Mo/NiAlN/NiAlON/SiO_2 coating was deposited via the optimized layer thickness. A good spectral selectivity with absorptance(α=0.936) and emittance(ε=0.09, T=80 ℃) was obtained. This method, which incorporates the optical simulation with the related experiments, provides a convenient approach to obtain the ideal solar selective absorbing coatings. | LIU Yingfang WANG Cong SUN Ying WU Yongxin NING Yuping WANG Wenwen ZHANG Yong ZHAO Shuxi | 2015 | Journal of the Chinese Ceramic Society2015，，4： | 1 |
| 13 | An Effective and Inducible System of TAL Effector-Mediated Transcriptional Repression in Arabidopsis显示文摘 | Sen Lin Yuanyuan Zhao Yingfang Zhu Michael Gosney Xin Deng Xiaohua Wang Jinxing Lin | 2016 | Molecular Plant2016，9，11： | 1 |
| 14 | Posterior hip capsular tenderness test improved the sensitivity and positive predictive value of FADIR test in diagnosing femoroacetabular impingement显示文摘To the Editor:Many physical examination tests are used to diagnose femoroacetabular impingement(FAI).The sensitivity and specificity of the flexion,abduction,and external rotation(FABER)test and the flexion,adduction,and internal rotation(FADIR)test for FAI diagnosis are quite different.Therefore,based on clinical practice,we proposed the possibility of adding a physical examination test to improve the accuracy of the traditional physical examinations. | Guanying Gao Cheng Wang Jianquan Wang Yingfang Ao Yan Xu | 2022 | Chinese Medical Journal2022，135，20： | 1 |
| 15 | miR-99a and -99b inhibit cervical cancer cell proliferation and invasion by targeting mTOR signaling pathway显示文摘 | Li Wang Lihua Chang Zhaorong Li Qing Gao Dongge Cai Yingfang Tian Lingxia Zeng Mu Li | 2014 | Medical Oncology2014，，5： | 1 |
| 16 | The Jasmine(Jasminum sambac)Genome Provides Insight into the Biosynthesis of Flower Fragrances and Jasmonates显示文摘Jasminum sambac(jasmine flower),a world-renowned plant appreciated for its exceptional flower fragrance,is of cultural and economic importance.However,the genetic basis of its fragrance is largely unknown.Here,we present the first de novo genome assembly of J.sambac with 550.12 Mb(scaffold N50=40.10 Mb)assembled into 13 pseudochromosomes.Terpene synthase(TPS)genes associated with flower fragrance are considerably amplified in the form of gene clusters through tandem duplications in the genome.Gene clusters within the salicylic acid/benzoic acid/theobromine(SABATH)and benzylalcohol O-acetyltransferase/anthocyanin O-hydroxycinnamoyltransferases/anthranilate N-hydroxycinnamoyl/benzoyltransferase/deacetylvindoline 4-O-acetyltransferase(BAHD)superfamilies were identified to be related to the biosynthesis of phenylpropanoid/benzenoid compounds.Several key genes involved in jasmonate biosynthesis were duplicated,causing an increase in copy numbers.In addition,multi-omics analyses identified various aromatic compounds and many genes involved in fragrance biosynthesis pathways.Furthermore,the roles of JsTPS3 in b-ocimene biosynthesis,as well as JsAOC1 and JsAOS in jasmonic acid biosynthesis,were functionally validated.The genome assembled in this study for J.sambac offers a basic genetic resource for studying floral scent and jasmonate biosynthesis,and provides a foundation for functional genomic research and variety improvements in Jasminum. | Gang Chen Salma Mostafa Zhaogeng Lu Ran Du Jiawen Cui Yun Wang Qinggang Liao Jinkai Lu Xinyu Mao Bang Chang Quan Gan Li Wang Zhichao Jia Xiulian Yang Yingfang Zhu Jianbin Yan Biao Jin | 2023 | Genomics, Proteomics & Bioinformatics2023，21，1： | 0 |
| 17 | Bipolarized intrinsic faradaic layer on a semiconductor surface under illumination显示文摘Interface charge transfer plays a key role in the performance of semiconductors for different kinds of solar energy utilization,such as photocatalysis,photoelectrocatalysis,photochromism and photo-induced superhydrophilicity.In previous studies,different mechanisms have been used to understand interface charge transfer processes.However,the charge transfer mechanism at the solid/liquid interface remains a controversial topic.Here,taking TiO_(2) as a model,we find and prove,via experiments,the new characteristic of photo-induced bipolarity of the surface layer(reduction faradaic layer and oxidation faradaic layer)on a semiconductor for the first time.Different from energy level positions in the classic surface states transfer mechanism,the potential window of a surface faradaic layer is located out of the forbidden band.Moreover,we find that the reduction faradaic layer and oxidation faradaic layer serve as electron and hole transfer mediators in photocatalysis,while the bipolarity or mono-polarity of the surface layer on a semiconductor depends on the applied potential in photoelectrocatalysis.The new characteristic of bipolarity can also offer new insights into the charge transfer process at the semiconductor/liquid interface for solar energy utilization. | Mengfan Xue Zhiqiang Chu Dongjian Jiang Hongzheng Dong Pin Wang Gengzhi Sun Yingfang Yao Wenjun Luo Zhigang Zou | 2023 | National Science Review2023，10，4： | 0 |
| 18 | Photosynthetic microorganisms coupled photodynamic therapy for enhanced antitumor immune effect显示文摘The ideal photodynamic therapy(PDT)should effectively remove the primary tumor,and produce a stronger immune memory effect to inhibit the tumor recurrence and tumor metastasis.However,limited by the hypoxic and immunosuppressive microenvironment,the PDT efficiency is apparently low.Here,Chlorella(Chl.)is exploited to enhance local effect by producing oxygen to reverse hypoxia,and release adjuvants to reverse immunosuppressive microenvironment to enhance abscopal effect afterwards.Results from different animal models indicated that Chl.could enhance local effect and PDT related immune response.Ultimately,Chl.coupled PDT elicited anti-tumor effects toward established primary tumors(inhibition rate:90%)and abscopal tumors(75%),controlled the challenged tumors(100%)and alleviated metastatic tumors(90%).This Chl.coupled PDT strategy can also produce a stronger anti-tumor immune memory effect.Overall,this Chl.coupled PDT strategy generates enhanced local tumor killing,boosts PDT-induced immune responses and promotes anti-tumor immune memory effect,which may be a great progress for realizing systemic effect of PDT. | Haoran Wang Honghui Liu Yunfei Guo Wenjing Zai Xianghui Li Wei Xiong Xiaozhi Zhao Yingfang Yao Yiqiao Hu Zhigang Zou Jinhui Wu | 2022 | Bioactive Materials2022，7，6： | 0 |
| 19 | Isolation and comparative proteomic analysis of mitochondria from the pulp of ripening citrus fruit显示文摘Mitochondria are crucial for the production of primary and secondary metabolites,which largely determine the quality of fruit.However,a method for isolating high-quality mitochondria is currently not available in citrus fruit,preventing high-throughput characterization of mitochondrial functions.Here,based on differential and discontinuous Percoll density gradient centrifugation,we devised a universal protocol for isolating mitochondria from the pulp of four major citrus species,including satsuma mandarin,ponkan mandarin,sweet orange,and pummelo.Western blot analysis and microscopy confirmed the high purity and intactness of the isolated mitochondria.By using this protocol coupled with a label-free proteomic approach,a total of 3353 nonredundant proteins were identified.Comparison of the four mitochondrial proteomes revealed that the proteins commonly detected in all proteomes participate in several typical metabolic pathways(such as tricarboxylic acid cycle,pyruvate metabolism,and oxidative phosphorylation)and pathways closely related to fruit quality(such asγ-aminobutyric acid(GABA)shunt,ascorbate metabolism,and biosynthesis of secondary metabolites).In addition,differentially abundant proteins(DAPs)between different types of species were also identified;these were found to be mainly involved in fatty acid and amino acid metabolism and were further confirmed to be localized to the mitochondria by subcellular localization analysis.In summary,the proposed protocol for the isolation of highly pure mitochondria from different citrus fruits may be used to obtain high-coverage mitochondrial proteomes,which can help to establish the association between mitochondrial metabolism and fruit storability or quality characteristics of different species and lay the foundation for discovering novel functions of mitochondria in plants. | Xin Li Yingfang Chai Hongbin Yang Zhen Tian Chengyang Li Rangwei Xu Chunmei Shi Feng Zhu Yunliu Zeng Xiuxin Deng Pengwei Wang Yunjiang Cheng | 2021 | Horticulture Research2021，8，1： | 0 |
| 20 | Thiourea-assisted coating of dispersed copper electrocatalysts on Si photocathodes for solar hydrogen production显示文摘Photoelectrochemical water splitting can convert solar energy into clean hydrogen energy for storage.It is desirable to explore non-precious electrocatalysts for practical applications of a photoelectrode in a large scale.Here,we developed a facile spin-coating and in-situ photoelectrochemical reduction method to prepare a dispersed Cu electrocatalyst on a Si photocathode,which improves the performance remarkably.We find that thiourea in the precursor solution for spin-coating plays an important role in obtaining dispersed Cu particles on the surface of a Si photoelectrode.With thiourea in the precursor,the Cu/Si photocathode shows higher performance than the one without thiourea.Moreover,the Cu/Si photocathode also indicates good stability after 16 h illumination. | Pin Wang Ziyu Yin Linfeng Gao Hui Li Tongyu Zhang Qing Shen Jun Lv Yingfang Yao Wenjun Luo Zhigang Zou | 2020 | Journal of Energy Chemistry2020，29，1： | 0 |
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