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124篇 您的检索式:作者名="Morris Smith"
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1Radiofrequency ablation for early oesophageal squamous neoplasia:Outcomes form United Kingdom registry显示文摘AIM:To report outcomes on patients undergoing radiofrequency ablation(RFA)for early oesophageal squamous neoplasia from a National Registry.METHODS:A Prospective cohort study from 8 tertiary referral centres in the United Kingdom.Patients with squamous high grade dysplasia(HGD)and early squamous cell carcinoma(ESCC)confined to the mucosa were treated.Visible lesions were removed by endoscopic mucosal resection(EMR)before RFA.Following initial RFA treatment,patients were followed up 3monthly.Residual flat dysplasia was treated with RFA until complete reversal dysplasia(CR-D)was achieved or progression to invasive Squamous cell cancer defined as infiltration into the submucosa layer or beyond.The main outcome measures were CR-D at 12 mo from start of treatment,long term durability,progression to cancer and adverse events.RESULTS:Twenty patients with squamous HGD/ESCC completed treatment protocol.Five patients(25%)had EMR before starting RFA treatment.CR-D was 50%at12 mo with a median of 1 RFA treatment,mean 1.5(range 1-3).Two further patients achieved CR-D with repeat RFA after this time.Eighty per cent with CR-D remain dysplasia free at latest biopsy,with median follow up 24 mo(IQR 17-54).Six of 20 patients(30%)progressed to invasive cancer at 1 year.Four patients(20%)required endoscopic dilatations for symptomatic structuring after treatment.Two of these patients have required serial dilatations thereafter for symptomatic dysphagia with a median of 4 dilatations per patient.The other 2 patients required only a single dilatation to achieve an adequate symptomatic response.One patient developed cancer during follow up after end of treatment protocol.CONCLUSION:The role of RFA in these patients re-mains unclear.In our series 50%patients responded at12 mo.These figures are lower than limited published data.Rehan J Haidry Mohammed A Butt Jason Dunn Matthew Banks Abhinav Gupta Howard Smart Pradeep Bhandari Lesley Ann Smith Robert Willert Grant Fullarton Morris John Massimo Di Pietro Ian Penman Marco Novelli Laurence B Lovat 2013World Journal of Gastroenterology2013,19,36:7
2Chronic actinic dermatitis: an immunohistologic and photobiologic study 显示文摘Norris PG Morris J Smith NP 1989J Am Acad Dermatol1989,21,5:1
3Membranous complexes characteristic of melanocytes derived from patients with Hermansky- Pudlak syndrome type 1 are macroautophagosomal entities of the lysosomal compartment显示文摘Smith JW Koshoffer A Morris RE 2005Pigment Cell Res2005,18,:1
4Host range studies for tomato chlorosis virus,and Cucumber vein yellowing virus transmitted by Bemisia tat)aci (Gennadius) 显示文摘Jane Morris Elspeth Steel Penny Smith 2006European Journal of Plant Pathology2006,114,:1
5Potato spindle tuber disease:procedures for detection of viroid RNA and certification of disease free of viroid RNA and certification of disease-free potato tubers显示文摘Morris T J E M Smith 1977Phytopathology1977,67,:1
6Inheritance and effect on ripening of antisense polygalacturonase genes in transgenic tomatoes显示文摘Smith CJ Watson CF Morris PC 1990Plant Mol Biol1990,14,3:1
7Alkylation of aromaticswith ethylene and propylene: recent developments in commercial processes显示文摘Thomas F Degnan Jr C Morris Smith Chaya R Venkat 2001Appl CatalA2001,221,:1
8Uptake and transformation of soil-trinitrotoluene by cool-season grasses显示文摘DURINGER J M MORRIE CRAIG A SMITH D J 2010Environmental science&technology2010,44,16:1
9Potential role of endocrine gastrin in the colonic adenoma carcinoma sequence显示文摘Watson SA Morris TM McWilliams DF Harris J Evans S Smith A 2002Br J Cancer2002,87,:1
10Antisense RNA inhibition ofpolygalacturonase gene expression in transgenic tomatoes显示文摘SMITH C J S WATSON C F RAY J’ BIRD C R MORRIS PC SCHUCH W GRIERSON D 1988Na-ture1988,334,:1
11Unrelated umbilical cord blood transplantation in adult patients显示文摘Gwynn D Long Mary Laughlin Bella Madan Joanne Kurtzberg Cristina Gasparetto Ashley Morris David Rizzieri Clayton Smith James Vredenburgh Edward C Halperin Gloria Broadwater Donna Niedzwiecki Nelson J Chao 2003Biology of Blood and Marrow Transplantation2003,,:1
12Inheritance and effect on ripening of antisense polygalacturonase genes in transgenic tomatoes显示文摘Smith C J S Watson C F Morris P C 1990Plant Molecular Biology1990,14,3:1
13Nitrogen and phosphorus removal from plant nursery runoff in vegeta- ted and unvegetated subsurface flow wetlands 显示文摘Huett D O Morris S G Smith G 2005Water Research2005,39,14:1
14Inheritance and effect on ripening of antisense polygalacturonase gene in transgenic tomatoes显示文摘Smith CJS Watson CF Morris PC 1990PMB1990,14,3:1
15Directions for future research in project management: the main findings of a UK government-funded research network 显示文摘Mark Winter Charles Smith Peter Morris Svetlana Cicmil 2006International Journal of Project Management2006,,24:1
16Cholera in Haiti: reproductive numbers and vaccination coverage estimates 显示文摘Mukandavire Z Smith DL Morris JG Jr 2013Sci Rep2013,,3:1
17Inheritance and effect on ripening of antisense polygalacturonase gene in transgenictomatoes显示文摘Smith C J S Watson C F Morris P C 1990PMB1990,14,3:1
18Antisense RNA inhibition of polygalacturonase gene expression in transgenic tomatoes显示文摘SMITH C J S WARSON C F RAY J BIRD C R MORRIS P C SCHUCH W GRIERSON D 1958Nature1958,334,6184:1
19Inheritance and effect on ripening of antisense polygalacturonase genes in transgenic tomatoes显示文摘SMITH C J S WATSON C F MORRIS P C BIRD C R SEYMOUR G B GRAY J E ARNOLD C TUCKER G A SCHUCH W HARDING S GRIERSON D 1990Plant Molecular Biology1990,14,3:1
20Chromatin cleavage in apoptosis: association with condensed chromatin morphology and dependence on macromolecular synthesis 显示文摘Wyllie A H Morris R G Smith A L 1984J Pathol1984,142,:1
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