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| 1 | China's wetland change (1990-2000) determined by remote sensing显示文摘Two wetland maps for the entire China have been produced based on Landsat data acquired around 1990 and 2000. Wetlands in China have been divided into 3 broad categories with 15 sub-categories except rice fields. In 1990, the total wetland area in China was 355208 km2 whereas in 2000 it dropped to 304849 km2 with a net loss of 50360 km2. During an approximate 10-year period, inland wetland reduced from 318326 to 257922 km2, coastal wetland dropped from 14335 to 12015 km2, while artificial wetland increased from 22546 to 34911 km2. The greatest natural wetland loss occurred in Heilongjiang, Inner Mon- golia, and Jilin with a total loss of over 57000 km2 of wetland. In western China, over 13000 km2 of wetlands were newly formed in Xinjiang, Tibet, and Qinghai. About 12000 km2 of artificial wetlands were also added for fish farm and reservoir constructions. The newly formed wetlands in western China were caused primarily by climate warming over that region whereas the newly created artificial wetlands were caused by economic developments. China’s wetland loss is caused mainly by human activities. | Peng Gong ZhenGuo Niu Xiao Cheng KuiYi Zhao DeMin Zhou JianHong Guo Lu Liang XiaoFeng Wang DanDan Li HuaBing Huang et al. | 2010 | Science China Earth Sciences2010，53，7： | 28 |
| 2 | Surveillance, epidemiology, and pathogen spectrum of hand, foot, and mouth disease in mainland of China from 2008 to 2017显示文摘Hand,foot and mouth disease(HFMD)was reported in May 2,2008 to be the 38th legally notifiable disease in China's National Notifiable Disease Reporting and Surveillance System.In order to solve the infection,an extensive three-level HFMD surveillance laboratory network was established.In this study,the framework of that network is assessed and the incidence of HFMD in China from 2008 to 2017 is reported using a descriptive epidemiologic method.During these 10 years,a series of techniques have been widely applied in all the network laboratories.Using information and material obtained from the network,a virus bank and database containing 18,238 viruses were established.Nationally,18,184,834 HFMD cases,including 152,436 severe cases and 3633 fatal cases,were reported in mainland of China.The average annual incidence in the population was 133.99/100,000 people,with a maximum incidence of 205.06/100,000 people in 2014.The incidence and mortality rates of HFMD were the highest in children aged 1–2 years.The numbers of reported cases fluctuated,with a high incidence observed every 2 years.An overall increase in the number of reported cases was also observed throughout the study period.Despite this,the incidence of severe cases and the mortality rate have been decreasing.High-risk regions are located in southern,eastern,and central China.Two peaks of HFMD infection cases were observed annually except for Northeast China.Different proportions of enterovirus serotypes were observed during the studied years.The predominant enterovirus varies from year to year,but the disease severity is always closely related to the specific serotype.EV-A71 is the dominant serotype associated with severe and fatal cases,with constituent ratios of 70.03%and 92.23%,respectively.The studied highly sensitive and efficient surveillance network provides information that is critical for prevention and control of the disease.It is extremely necessary and important to continuously conduct extensive virological surveillance for HFMD. | Tianjiao Ji Taoli Han Xiaojuan Tan Shuangli Zhu Dongmei Yan Qian Yang Yang Song Aili Cui Yan Zhang Naiying Mao Songtao Xu Zhen Zhu Dandan Niu Yong Zhang Wenbo Xu | 2019 | Biosafety and Health2019，1，1： | 26 |
| 3 | Plasma spray of biofunctional(Mg, Sr)-substituted hydroxyapatite coatings for titanium alloy implants显示文摘Plasma-sprayed hydroxyapatite (HA) coatings have been widely utilized in load-bearing titanium alloy implants. In this study, Mg, Sr co-substituted HA ((Mg,Sr)-HA) nano-scale powders have been synthesized, which are further used to prepare (Mg,Sr)-HA coatings on Ti-6A1-4V alloys in order to improve the biological functions. The average size of (Mg,Sr)-HA nano particles is ~75nm. The average bonding strength for (Mg,Sr)-HA coating and samples after heat treatment at 500℃ or 600℃ for 3h are 26.17±2.11 MPa, 36.07±4.48 MPa and 37.07 ±2.95 MPa, respectively. There is a significantly increase of bonding strength likely due to low residual stress after heated treatment.MC3T3-E1 cells show a high proliferation rate when cultured with (Mg,Sr)-HA coating extract compared to the normal culture medium, which also exhibit large extension and depositi on of extracellular matrices when adhered on the coating surfaces. Thus, these (Mg,Sr)-HA coatings show high bonding strength and improved biological functions, which offer promising future applications in the fields of orthopedics and dentistry. | Lei Cao Ihsan Ullah Na Li Shiyu Niu Rujie Sun Dandan Xia Rui Yang Xing Zhang | 2019 | Journal of Materials Science & Technology2019，35，5： | 5 |
| 4 | Smartphones for sensing显示文摘简单、便携式的分析设备为个人照顾,临床的分析,在食物的变应原察觉,并且环境监视正在进入我们的每日的生活。Smartphones 最流行的 state-of-art 移动设备,为察觉到应用有显著潜力。physical-co-chemical 传感器的一个成长集合被嵌入;这些包括存取并且表现数据分析的加速表,麦克风,照相机,回转仪,和 GPS 单位。在这评论,我们讨论集中于包括代表性的电磁的、听觉的频率察觉到的 smartphone 的最近的工作,光、电气化学的传感器。这些能力的发展将以他们的表演导致更紧缩、小、划算、灵活、持久的设备。 | Fenghua Li Yu Bao Dandan Wang Wei Wang Li Niu | 2016 | Science Bulletin2016，61，3： | 2 |
| 5 | Surface hydrophobic modification enhanced catalytic performance of electrochemical nitrogen reduction reaction显示文摘Electrocatalytic nitrogen reduction reaction(NRR)is a sustainable approach for NH_(3)production with low energy consumption.However,competing hydrogen reduction reaction(HER)in aqueous solution results in low NH_(3)production and Faraday efficiency(FE).Here,MoS_(2)nanostructures with a hydrophobic surface are synthesized by alkyl thiols modification.Aerophilic and hydrophobic surface facilitates an efficient three-phase contact of N_(2),H_(2)O,and catalyst.Thus,localized concentrated N_(2)molecules can overcome the mass transfer limitation of N2 and depress the HER due to lowering the proton contacts.Although the active-sites decrease with the increase of the alkyl chain since the thiol may cover the active site,the optimized electrocatalyst achieves NH_(3)yield of 12.86×10^(-11)mol·cm^(-2)·s^(-1)at-0.25 V and 22.23%FE,which are 4.3 and 24 times higher than those of MoS2-CP electrocatalyst,respectively.The increased catalytic performance is attributed to the high N_(2)adsorption and depressed HER. | Lijuan Niu Ziwen Liu Guohua Liu Mengxuan Li Xupeng Zong Dandan Wang Li An Dan Qu Xiaoming Sun Xiayan Wang Zaicheng Sun | 2022 | Nano Research2022，15，5： | 2 |
| 6 | Electrodeposition of Ni micro/nano-structures显示文摘A quasi two-dimension electrodeposition method was used to prepare materials with arborized, tree-shaped, and membrane patterned micro/nano-structures. The morphology of the membrane patterned micro/nano-structure was characterized using scanning electron microscopy, and a mechanism for the morphology formation was suggested. The novel preparation method used in this study, which is proprietary to our research group, does not require a template and so has many advantages including controllable, low cost, large scale preparation. The electrolyte concentration and electrodeposition voltage had a significant effect on the resulting morphology. | NIU LianPing YE DanDan LI Feng ZHANG MingZhe | 2011 | Chinese Science Bulletin2011，56，32： | 1 |
| 7 | Excessive apoptosis and ROS induced by ethionine affect neural cell viability and differentiation显示文摘The central nervous system(CNS)diseases are still a major cause of morbidity and mortality throughout the world,which imposes heavy burden on the development of society.Ethionine is a non-proteinogenic amino acid having similar chemical structure and activity to that of methionine,with which it competes.Previous studies have confirmed that ethionine affects various cellular functions by inhibiting the biosynthesis of proteins,RNA,DNA,and phospholipids,or all of them.The relationship of ethionine with some CNS diseases,including neural tube defects,has been investigated recently.However,the detailed effects of ethionine on the nerve cell bioactivities and the underlying mechanisms have not been fully explored.Herein,we systematically investigated the influences of ethionine on the proliferation,differentiation,and apoptosis of neural stem cells(NSCs)and post-mitotic nerve cells.We demonstrated that ethionine inhibited cell viability by disrupting the balance between proliferation and apoptosis,prevented NSCs from differentiating into neurons and astrocytes,and blocked cell progression from G1 to S phase via reducing cyclin D1 function in nerve cells including NSCs,a mouse hippocampal neuron cell line(HT-22),and a mouse brain neuroma cell line(Neuro-2a).We speculated that the inhibitory effect of ethionine on cell viability and differentiation are associated with increased reactive oxygen species production.Our results also supported the concept that ethionine may be an underlying cause of abnormal folate metabolism-induced CNS diseases.Our findings may provide important direction for the application of abnormal folate metabolism-induced CNS diseases in future NSC-based therapies. | Li Zhang Dandan Li Juan Zhang Ping Yan Xueqin Liu Lei Wang Ajab Khan Zhizhen Liu Jianbing Mu Jun Xu Bo Niu Jun Xie | 2020 | Acta Biochimica et Biophysica Sinica2020，52，10： | 1 |
| 8 | Observation of CO2^++ dication in the dayside Martian upper atmosphere显示文摘Doubly charged positive ions(dications)are an important component of planetary ionospheres because of the large energy required for their formation.Observations of these ions are exceptionally difficult due to their low abundances;until now,only atomic dications have been detected.The Neutral Gas and Ion Mass Spectrometer(NGIMS)measurements made on board the recent Mars Atmosphere and Volatile Evolution mission provide the first opportunity for decisive detection of molecular dications,CO2^++in this case,in a planetary upper atmosphere.The NGIMS data reveal a dayside averaged CO2^++distribution declining steadily from 5.6 cm^−3 at 160 km to below 1 cm^−3 above 200 km.The dominant CO2^++production mechanisms are double photoionization of CO2 below 190 km and single photoionization of CO2^+at higher altitudes;CO2++destruction is dominated by natural dissociation,but reactions with atmospheric CO2 and O become important below 160 km.Simplified photochemical model calculations are carried out and reasonably reproduce the data at low altitudes within a factor of 2 but underestimate the data at high altitudes by a factor of 4.Finally,we report a much stronger solar control of the CO2^++density than of the CO2+density. | Hao Gu Jun Cui DanDan Niu LongKang Dai JianPing Huang XiaoShu Wu YongQiang Hao Yong Wei | 2020 | Earth and Planetary Physics2020，4，4： | 1 |
| 9 | Microbial selection pressure is not a prerequisite for granulation:Dynamic granulation and microbial community study in a completemixing bioreactor显示文摘 | Dandan Zhou Shu Niu Yongjiao Xiong | 2014 | Bioresource Technology2014，，161： | 1 |
| 10 | HBx genotype D represses GSTP1 expression and increases the oxidative level and apoptosis in HepG2 cells显示文摘 | Dandan Niu Jianhua Zhang Yudan Ren Huixing Feng Wei Ning Chen | 2008 | Molecular Oncology2008，，1： | 1 |
| 11 | High yield recombinant thermostable at -amylase production using an improved Bacillus licheniformis system显示文摘 | NIU Dandan ZUO Zhimi SHI Guiyang | 2009 | Microb Cell Fact2009，58，8： | 1 |
| 12 | Wang Development of a pair of bifunctional expression vectors for Escherichia coli and Bacillus licheniformis显示文摘 | Dandan Niu Zheng-Xiang | 2007 | J Ind Microbiol Biotechnol2007，34，： | 1 |
| 13 | Comparative studies on efficiency of china' s regional innovation system on the basis of cooperation measurement model显示文摘 | Niu Dandan Wang Renwen Zhang Xinyue | 2013 | Journal of Emerging Trends in Economics and Management Sciences2013，4，2： | 1 |
| 14 | Fe_(2)Mo_(3)O_(8)/XC-72 electrocatalyst for enhanced electrocatalytic nitrogen reduction reaction under ambient conditions显示文摘To perform the electrochemical nitrogen reduction reaction(NRR)under milder conditions for sustainable ammonia production,electrocatalysts should exhibit high selectivity,activity,and durability.However,the key restrictions are the highly stable N≡N triple bond and the competitive hydrogen evolution reaction(HER),which make it difficult to adsorb and activate N2 on the surface of electrocatalysts,leading to a low ammonia yield and Faraday efficiency.Inspired by the enzymatic nitrogenase process and using the Fe-Mo as the active center,here we report supported Fe_(2)Mo_(3)O_(8)/XC-72 as an effective and durable electrocatalyst for the NRR.Fe_(2)Mo_(3)O_(8)/XC-72 exhibited NRR activity with an NH3 yield of 30.4μg·h^(−1)·mg^(−1)(−0.3 V)and a Faraday efficiency of 8.2%(−0.3 V).Theoretical calculations demonstrated that the electrocatalytic nitrogen fixation mechanism involved the Fe atom in the Fe_(2)Mo_(3)O_(8)/XC-72 electrocatalyst acting as the main active site in the enzymatic pathway(*NH2→*NH3),which activated nitrogen molecules and promoted the NRR performance. | Guohua Liu Lijuan Niu Zhixue Ma Li An Dan Qu Dandan Wang Xiayan Wang Zaicheng Sun | 2022 | Nano Research2022，15，7： | 0 |
| 15 | Premature aging of skeletal stem/progenitor cells rather than osteoblasts causes bone loss with decreased mechanosensation显示文摘A distinct population of skeletal stem/progenitor cells(SSPCs)has been identified that is indispensable for the maintenance and remodeling of the adult skeleton.However,the cell types that are responsible for age-related bone loss and the characteristic changes in these cells during aging remain to be determined.Here,we established models of premature aging by conditional depletion of Zmpste24(Z24)in mice and found that Prx1-dependent Z24 deletion,but not Osx-dependent Z24 deletion,caused significant bone loss.However,Acan-associated Z24 depletion caused only trabecular bone loss.Single-cell RNA sequencing(sc RNA-seq)revealed that two populations of SSPCs,one that differentiates into trabecular bone cells and another that differentiates into cortical bone cells,were significantly decreased in Prx1-Cre;Z24^(f/f)mice.Both premature SSPC populations exhibited apoptotic signaling pathway activation and decreased mechanosensation.Physical exercise reversed the effects of Z24depletion on cellular apoptosis,extracellular matrix expression and bone mass.This study identified two populations of SSPCs that are responsible for premature aging-related bone loss.The impairment of mechanosensation in Z24-deficient SSPCs provides new insight into how physical exercise can be used to prevent bone aging. | Ruici Yang Dandan Cao Jinlong Suo Lingli Zhang Chunyang Mo Miaomiao Wang Ningning Niu Rui Yue Weiguo Zou | 2023 | Bone Research2023，11，3： | 0 |
| 16 | Wavelike perturbations in Titan’s ionosphere and their compositional variation:A preliminary survey of Cassini Ion Neutral Mass Spectrometer measurements显示文摘Wavelike perturbations in the ionosphere of Titan,the largest satellite of Saturn,are explored based on the Cassini Ion Neutral Mass Spectrometer(INMS)measurements.Strong wavelike perturbations are identified for more than twenty ion species,from simple ones such as N^(+)and CH_(4)^(+)to complex ones such as C_(2)H_(3)CNH^(+)and C_(4)H_(7)^(+).Simultaneous wavelike perturbations in background N_(2),indicative of atmospheric gravity waves,are also observed,motivating us to speculate that the INMS-derived ion perturbations are wave-driven.The amplitudes of the ion perturbations are found to be larger than that of the N_(2)perturbations.Clear compositional variation is revealed by the data:heavier ion species exhibit greater amplitudes.Such observations might be understood based on considerations either of force balance or chemical loss in Titan’s ionosphere. | ShiQi Wu DanDan Niu WeiQin Sun XiaoShu Wu HaoYu Lu Jun Cui | 2022 | Earth and Planetary Physics2022，6，6： | 0 |
| 17 | A nanoagent for concurrent therapy of breast cancer bone metastasis and cancer-induced bone pain through SLC7A11 interruption and photodynamic therapy显示文摘Bone metastasis,a life-threatening complication of advanced breast cancer,is often accompanied by debilitating pain(cancer-induced bone pain,CIBP)that severely impairs life quality and survival.The concurrent treatment of bone metastases and CIBP remains a clinical challenge because the therapeutic options are limited.In this study,we construct a near-infrared light-activated nano-therapeutic system to meet this conundrum.In detail,sorafenib(SRF)and photosensitizer(chlorin e6,Ce6)are encapsulated into mesoporous hydroxyapatite nanoparticles(HANPs),which are further functionalized with hyaluronic acid(HA)to obtain HA-SRF/Ce6@HANPs system.The designed nanoplatform destroys tumor cells in vitro and in vivo via the synergism of SRF(interrupting the exchange of cystine/glutamate by inhibiting SLC7A11)and photodynamic therapy(PDT,inducing reactive oxygen species generation).The decrease in tumor burden and reduction of extracellular glutamate significantly attenuate CIBP in mice model with developing bone cancer.Moreover,the combination of HA-SRF/Ce6@HANPs and PDT inhibit osteoclasts activation,promote osteoblast differentiation and accelerate bone repair.Overall,the nanoagent with good biocompatibility may provide an effective therapy method for the concurrent treatment of breast cancer bone metastasis and CIBP. | Qi Fu Zhongming Lian Mengya Niu Yaru Huang Yanqiu Ai Long He Dandan Zhang Cuixia Zheng Jian-Jun Yang Lei Wang Dandan Tian | 2024 | Chinese Chemical Letters2024，35，2： | 0 |
| 18 | Tuning the performance of nitrogen reduction reaction by balancing the reactivity of N_(2) and the desorption of NH_(3)显示文摘Electrochemical reduction of nitrogen to ammonia under mild conditions provides an intriguing approach for energy conversion. A grand challenge for electrochemical nitrogen reduction reaction (NRR) is to design a superior electrocatalyst to obtain high performance including high catalytic activity and selectivity. In the NRR process, the three most important steps are nitrogen adsorption, nitrogen activation, and ammonia desorption. We take MoS_(2) as the research object and obtain catalysts with different electronic densities of states through the doping of Fe and V, respectively. Using a combination of experiments and theoretical calculations, it is demonstrated that V-doped MoS_(2) (MoS_(2)-V) shows better nitrogen adsorption and activation, while Fe-doped MoS_(2) (MoS_(2)-Fe) obtains the highest ammonia yield in experiments (20.11 µg·h^(−1)·mg^(−1)cat.) due to its easier desorption of ammonia. Therefore, an appropriate balance between nitrogen adsorption, nitrogen activation, and ammonia desorption should be achieved to obtain highly efficient NRR electrocatalysts. | Lijuan Niu Dandan Wang Kang Xu Weichang Hao Li An Zhenhui Kang Zaicheng Sun | 2021 | Nano Research2021，14，11： | 0 |
| 19 | Role of oxygen vacancy in rare-earth-free LiCa_(3)Mg(VO_(4))_(3) phosphor: Enhancing photoluminescence by heat-treatment in oxygen flow显示文摘As a kind of white light emitting diode(w-LED)with many advantages,rare-earth-free vanadate phosphor has attracted more and more attention.The oxygen vacancies and other surface defects in vanadate oxide have obvious effects on its structure and properties.In order to reveal the specific effects,we heat-treat the original LiCa_(3)Mg(VO_(4))_(3)(LCMV)in an oxygen flow with different time to decrease oxygen vacancies,and find that the lattice distortion of[VO_(4)]tetrahedron caused by oxygen vacancy is effectively reduced.Meanwhile,the crystallinity of the treated samples increases,the surface defects decreases,and the fluorescence intensity increases.The variation of photoluminescence quantum yield(PLQY)with oxygen treatment time is as follows:the enhancement effect firstly reaches the strongest(69.34%)within one hour,then begins to decline after two hours,and finally reaches the platform after three hours and remains basically unchanged.The reason for the enhancement of PLQY is the decrease of oxygen vacancy after one-hour treatment,and the reason for the decrease of PLQY after a further increased treatment time is that the absorption of oxygen and water in air caused by excessive surface defects introduced by oxygen treatment. | Yixuan Lv Yijun Zhang Le Shi Jian-Wen Shi Jun Li Zhihui Li Xin Ji Dandan Ma Yonghong Cheng Chunming Niu | 2021 | Journal of Materials Science & Technology2021，，20： | 0 |
| 20 | Is Solar Wind electron precipitation a source of neutral heating in the nightside Martian upper atmosphere?显示文摘Solar Wind(SW)electron precipitation is able to deposit a substantial amount of energy in the nightside Martian upper atmosphere,potentially exerting an influence on its thermal structure.This study serves as the first investigation of such an issue,with the aid of the simultaneous measurements of both neutral density and energetic electron intensity made on board the recent Mars Atmosphere and Volatile Evolution(MAVEN)spacecraft.We report that,from a statistical point of view,the existing measurements do not support a scenario of noticeable neutral heating via SW electron precipitation.However,during 3%−4%of the MAVEN orbits for which data are available,strong correlation between nightside temperature and electron intensity is observed,manifested as collocated enhancements in both parameters,as compared to the surrounding regions.In addition,our analysis also indicates that neutral heating via SW electron precipitation tends to be more effective at altitudes below 160 km for integrated electron intensities above 0.01 ergs·cm^−2·s^−1 over the energy range of 3−450 eV.The results reported here highlight the necessity of incorporating SW electron precipitation as a heat source in the nightside Martian upper atmosphere under extreme circumstances such as during interplanetary coronal mass ejections. | LongKang Dai Jun Cui DanDan Niu Hao Gu YuTian Cao XiaoShu Wu HaiRong Lai | 2021 | Earth and Planetary Physics2021，5，1： | 0 |
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