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| 1 | Endoscopic transluminal pancreatic necrosectomy using a self-expanding metal stent and high-flow water-jet system显示文摘Walled-off pancreatic necrosis and a pancreatic abscess are the most severe complications of acute pancreatitis. Surgery in such critically ill patients is often associated with significant morbidity and mortality within the first few weeks after the onset of symptoms. Minimal invasive approaches with high success and low mortality rates are therefore of considerable interest. Endoscopic therapy has the potential to offer safe and effective alternative treatment. We report here on 3 consecutive patients with infected walled-off pancreatic necrosis and 1 patient with a pancreatic abscess who underwent direct endoscopic necrosectomy 19-21 d after the onset of acute pancreatitis. The infected pancreatic necrosis or abscess was punctured transluminally with a cystostome and, after balloon dilatation, a non-covered self-expanding biliary metal stent was placed into the necrotic cavity. Following stent deployment, a nasobiliary pigtail catheter was placed into the cavity to ensure continuous irrigation. After 5-7 d, the metal stent was removed endoscopically and the necrotic cavity was entered with a therapeutic gastroscope. Endoscopic debridement was performed via the simultaneous application of a high-flow water-jet system; using a flush knife, a Dormia basket, and hot biopsy forceps. The transluminal endotherapy was repeated 2-5 times daily during the next 10 d. Supportive care included parenteral antibiotics and jejunal feeding. All patients improved dramatically and with resolution of their septic conditions; 3 patients were completely cured without any further complications or the need for surgery. One patient died from a complication of prolonged ventilation severe bilateral pneumonia, not related to the endoscopic procedure. No procedure related complications were observed. Transluminal endoscopic necrosectomy with temporary application of a self-expanding metal stent and a high-flow water-jet system shows promise for enhancing the potential of this endoscopic approach in patients with walled-off pancreatic necrosis and/or a pancreatic abscess. | István Hritz Roland Fejes András Székely Iván Székely László Horváth gnes Sárkány ron Altorjay László Madácsy | 2013 | World Journal of Gastroenterology2013，19，23： | 10 |
| 2 | Ureaplasma Urealyticum or Mycoplasma Hominis Infections and Semen Quality of Infertile Men in Abidjan显示文摘Objective To determine the prevalence of U. urealyticum and M. hominis in semen samples collected from men admitted in clinic for infertility, and to compare the quality of these semen samples. Methods A total of 1 058 semen samples collected were investigated. Sperm semiological assays were performed according to the guidelines of the World Health Organisation (WHO). Semen were examined by Mycoplasma IST for the detection of mycoplasma. Semen culture on agar media was used to detect other microorganisms. Chlamydia was detected using direct fluorescent assay (DFA) of Clamydia Trachomatis. Results Among 1 058 semen samples, microorganisms were detected in 638 (60.3%). The infected sperms consisted of mycoplasma alone in 507 cases (47.9%), mycoplasma and other microorganisms in 98 (9.3%), giving in all 605 (57.2%) samples infected with mycoplasma. The last 33 (3.1%) consisted of other microorganisms alone. The frequency of U.urealyticum, M. hominis and mixed genital infections detected in semen samples of infertile men were 39%, 23.8% and 5.6%, respectively. The rates of abnormal semen parameters recorded among patients infected with mycoplasma were for volume (22.2%-25%), viscosity (29.6%-43.5%), pH (64.7%-72.9%), motility (80.8%-93.8%), morphology (36.3%-47.9%), sperm concentration (53.3%-58.3%) and leukocyte count (51.4%-58.3%). Conclusion Frequency of U. urealyticum infection was higher than that of M. hominis. Mycoplasma infections were associated with disorders of pH, motility and sperm concentration. In addition M. hominis infection affected spermatozoa morphology. Therefore, screening of U. urealyticum and M. hominis for routine semen analysis is clinically relevant in Abidjan. | Zinzendorf NY Kouassi-Agbessi BT Lathro JS Don C Kouadio L Loukou YG | 2008 | Journal of Reproduction and Contraception2008，19，2： | 3 |
| 3 | Triiodothyronine accelerates differentiation of rat liver progenitor cells into hepatocytes显示文摘 | Viktória László Katalin Dezs? Kornélia Baghy Veronika Papp Ilona Kovalszky Géza Sáfrány Snorri S. Thorgeirsson Peter Nagy Sándor Paku | 2008 | Histochemistry and Cell Biology2008，，5： | 2 |
| 4 | Effect of various surface modifications of wood flour on the properties of PP/wood composites显示文摘 | Lívia Dányádi János Móczó Béla Pukánszky | 2009 | Composites Part A2009，，2： | 2 |
| 5 | Co-localization of carbon monoxide and nitric oxide synthesizing enzymes in the human urethral sphincter显示文摘 | Ho KM Ny L MeMurray G et ol | 1999 | J Urol1999，161，6： | 1 |
| 6 | Cord blood leptinlevelsin normal pregjiancies,pregnancy induced hypertension andgestationaldiabetesmellitus显示文摘 | Silva NY Tennekoon KH Senanayake L | 2008 | Ceylon Medical Journal CMJ2008，，： | 1 |
| 7 | High abundance of plasma cells secreting transglutaminase 2-specific IgA autoantibodies with limited somatic hypermutation in celiac disease intestinal lesions 显示文摘 | Di Niro R Mesin L Zheng NY | 2012 | Nature medicine2012，18，3： | 1 |
| 8 | Stimulation of cell defense mechanism of bovine endometrium by temporal colonization with selected strains of lactobacilli显示文摘 | Kummer V Lány P Masková J | 1997 | Vet Med1997，42，8： | 1 |
| 9 | Cholinergic nerves in human corpus cavernosum and spongiosum contain nitric oxide synthase and heme oxygenase显示文摘 | Hedlund P Ny L Alm P | 2000 | J Urol2000，164，31： | 1 |
| 10 | Atopic dermatitis: review of im- munopathogenesis and advances in immunosuppressive therapy显示文摘 | Meagher L I Wines NY Cooper AJ | 2002 | Australas J Dermato12002，43，4： | 1 |
| 11 | Fluid Inclusion Study of Stibnite using Infrared Microscopy; An Example from the Brouzils Antimony Deposit (Vendée,Armorican Massif,France)显示文摘 | Bailly L Bouchot V Bény C | 2000 | Economic Geology2000，95，： | 1 |
| 12 | Effect of various surface modifications of wood flour on the properties of PP/wood Composites显示文摘 | Lívia Dányádi János Móczó Béla Pukánszky | 2010 | Composites Part A:Applied Polymer Science2010，41，2： | 1 |
| 13 | The influence of electro-acupuncture on neural plasticity in acute cerebral infarction 显示文摘 | Ren L Zhang WA Fang NY | 2008 | Neurol Res2008，30，9： | 1 |
| 14 | Directed differentiation of human embryonic stem ceils into functional retinal pigment epithelium cells 显示文摘 | Idelson M Alper R Obolensky A Shushan EB Hemo L Cohen NY | 2009 | Cell Stem Ceii2009，5，4： | 1 |
| 15 | Cord blood leptin level s in normal pregnancies, pregnancy induced hypertomion and geetatienal diabetes mellitus 显示文摘 | Silva NY Tennekoon KH Senanayake L | 2008 | Ceylon Med J2008，53，3： | 1 |
| 16 | Endothelin-1 stimulates cardiac fibroblast proliferation through activation of protein kinase C显示文摘 | Gray M Honbo NY | 2000 | J Mol Cell Cardiol2000，32，： | 1 |
| 17 | Fracture and failure behavior of basalt fiber mat-reinforced vinylester/epoxy hybrid resins as a function of resin composition and fiber surface treatment显示文摘 | T. Czigány K. P?l?skei J. Karger-Kocsis | 2005 | Journal of Materials Science2005，，21： | 1 |
| 18 | Endothelin-1 stimulates cardiac fibroblast proliferation through activation of prohfin kinase C显示文摘 | Piacentint L Gray M Honbo NY | 2000 | J Mol Cell Card2000，32，4： | 1 |
| 19 | The influence of electroacupuncture on neural plasticity in acute cerebral infarct-tion显示文摘 | Ren L Zhang WA Fang NY etal | 2008 | Neurol Res2008，30，9： | 1 |
| 20 | International comparative analyses of healthcare risk management显示文摘 | Sun NY Wang L Zhou J | 2011 | Journal of Evidence-Based Medcine2011，4，： | 1 |
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