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| 1 | 酒精摄入、心脏生物标志物和心房颤动风险与不良结局显示文摘酒精摄入和新发心房颤动相关性证据不一,尤其是在低剂量下。该研究评估欧洲队列在整个饮酒范围内酒精摄入、生物标志物和新发心房颤动的关系。方法和结果:在一个以社区为基础的汇集队列中,研究者随访107845人,以评估酒精摄入(酒精种类和饮酒方式)与新发心房颤动的关系。研究者收集经典心血管病危险因素和新发心力衰竭的信息,并检测生物标记物氨基末端脑钠肽前体和高敏肌钙蛋白I。 | 陈嘉睿(译) 练桂丽((审校) Csengeri D Sprünker NA Di Castelnuovo A Niiranen T Vishram-Nielsen JK Costanzo S S derberg S Jensen SM Vartiainen E Donati MB Magnussen C Camen S Gianfagna F L chen ML Kee F Kontto J Mathiesen EB Koenig W Stefan B de Gaetano G J rgensen T Kuulasmaa K Zeller T Salomaa V Iacoviello L Schnabel RB | 2021 | 中华高血压杂志2021，29，2： | 9 |
| 2 | Therapeutic proteasome inhibition in experimental acute pancreatitis显示文摘AIM: To establish the therapeutic potential of proteasome inhibition, we examined the therapeutic effects of MG132 (Z-Leu-Leu-Leu-aldehyde) in an experimental model of acute pancreatitis.METHODS: Pancreatitis was induced in rats by two hourly intraperitoneal (ip) injections of cholecystokinin octapeptide (CCK; 2 x 100 μg/kg) and the proteasome inhibitor MG132 (10 mg/kg ip) was administered 30 min after the second CCK injection. Animals were sacrificed 4 h after the first injection of CCK.RESULTS: Administering the proteasome inhibitor MG132 (at a dose of 10 mg/kg, ip) 90 min after the onset of pancreatic inflammation induced the expression of cell-protective 72 kDa heat shock protein (HSP72) and decreased DNA-binding of nuclear factor-kB (NF-kB). Furthermore MG132 treatment resulted in milder inflammatory response and cellular damage, as revealed by improved laboratory and histological parameters of pancreatitis and associated oxidative stress.CONCLUSION: Our findings suggest that proteasome inhibition might be beneficial not only for the prevention, but also for the therapy of acute pancreatitis. | Tamás Letoha Liliána Z Fehér László Pecze Csaba Somlai Ilona Varga József Kaszaki Gábor Tóth Csaba Vizler László Tiszlavicz Tamás Takács | 2007 | World Journal of Gastroenterology2007，13，33： | 5 |
| 3 | 持续气道正压通气在预防阻塞性睡眠呼吸暂停患者心血管事件中的作用显示文摘阻塞性睡眠呼吸暂停(obstructive sleep apnea,OSA)导致阵发性低氧血症,夜间交感神经系统激活,血压、氧化应激和炎症指标的升高以及高凝血症。较大的胸内负压波动也会给心脏和大血管施加机械应力。基于人群和睡眠诊所的队列研究显示,OSA与心脑血管事件,特别是脑卒中相关。 | McEvoy RD Antic NA Heeley E Luo Y Ou Q Zhang X Mediano O Chen R Drager LF Liu Z Chen G Du B McArdle N Mukherjee S Tripathi M Billot L Li Q Lorenzi-Filho G Barbe F Redline S Wang J Arima H Neal B White DP Grunstein RR Zhong N Anderson CS 练桂丽 叶鹏 | 2016 | 中华高血压杂志2016，24，11： | 4 |
| 4 | 脂质组学改善传统危险因素预测的2型糖尿病患者的心血管事件显示文摘临床脂质测定并未显示出糖尿病或心血管病相关的脂质代谢改变的复杂性。脂质组学则能够评估可作为疾病风险潜在标志物的数百种脂质种类。方法:纳入来自糖尿病治疗和血管保护行动。 | 刘莉 叶鹏 Alshehry ZH Mundra PA Barlow CK Mellett NA Wong G McConville MJ Simes J Tonkin AM Sullivan DR Barnes EH Nestel PJ Kingwell BA Marre M Neal B Poulter NR Rodgers A Williams B Zoungas S Hillis GS Chalmers J Woodward M Meikle PJ | 2016 | 中华高血压杂志2016，24，10： | 3 |
| 5 | Focal cortical dysplasia: comparison of MRI and FDG-PET 显示文摘 | Kim S K Na D G Byun H S | 2000 | J Comput Assist Tomogr2000，24，2： | 1 |
| 6 | Nitric Oxide Is Required for Root Organogenesis 显示文摘 | Pagnussat G C Simontacchi M Puntarulo S and Lamatti- na L | 2002 | Plant Physiology2002，129，： | 1 |
| 7 | Management of high-risk hydatidiform mole and persistent gestational trophoblastic neoplasia:the Korean experience显示文摘 | Kim S J Na Y J Jung S G | | 0，，09： | 1 |
| 8 | Preparation and application of an oil soluble Co-Mo bimetallic catalyst for the hydrocrac- king of oil sands bitumen显示文摘 | Jeon S G Na J G Ko C H | 2011 | Energy & Fuels2011，25，10： | 1 |
| 9 | A new approach for prepara- tion of oil-soluble bimetallic dispersed catalyst from layered ammonium nickel molybdate显示文摘 | Jeon S G Na J G Ko C H et ai | 2011 | Materials Science and Engi neering: B2011，176，7： | 1 |
| 10 | Critical roles for excretorysecretory cysteine proteases during tissue invasion of Para-gonimus westermani newly excysted metacercariae显示文摘 | Na B K Kim S H Lee E G | 2006 | CellMicrobiol2006，8，： | 1 |
| 11 | Heat transfer and fluid flow in a partially or fully penetrated weld pool in gas tungsten are weld- ing显示文摘 | FAN H G TSAI H L NA S J | 2000 | International Journal of Heat and Mass Transfer2000，44，2： | 1 |
| 12 | Heat transfer and fluid flow in a partially or fully penetrated weld pool in gas tungsten arc welding 显示文摘 | Fan H G Tsai H L Na S J | 2000 | International Journal of Heat and Mass Transfer2000，44，2： | 1 |
| 13 | Arabidopsis research 2001显示文摘 | Eckardt NA Araki T Benning C Cubas P Goodrich J Jacobsen SE Masson P Nambara E Simon R Somerville S Wasteneys G | | 0，，09： | 1 |
| 14 | New insights into the aquatic photochemistry of fluoroquinolone antibiotics: Direct photodegradation, hydroxyl-radical oxidation, and antibacterial activity changes显示文摘 | GE L K NA G S ZHANG S Y | 2015 | Science of the Total Environment2015，，： | 1 |
| 15 | Gelsemium alkaloids, immunosuppressive agents from Gelsemium elegans 显示文摘 | XU Y K LIAO S G NA Z | 2012 | Fitoterapia2012，83，6： | 1 |
| 16 | Cytokine balance in kidney tissue from lupus nephritis patients显示文摘 | Uhm W S Na K Song G W | 2003 | Rheumatology2003，42，8： | 1 |
| 17 | Heat transfer and fluid flow in a partially or fully penetrated weld pool in gas tungsten arc welding显示文摘 | FAN H G TSAI H L NA S J | 2001 | International Journal of Heat and Mass Transfer2001，44，2： | 1 |
| 18 | Sonographic features offollicular variant papillary thyroid carcinomas in comparisonwith conventional papillary thyroid carcinomas 显示文摘 | KIM D S KIM J H NA D G | 2009 | JUltrasound Med2009，28，12： | 1 |
| 19 | Short-term predictors and long-term outcome after ruptured abdominal aortic aneurysm repair显示文摘 | Piper G Patel NA Chandela S | 2003 | Am Surg2003，69，8： | 1 |
| 20 | The draft genome of the transgenic tropical fruit tree papaya ( Carica pap aya Linnaeus ) 显示文摘 | MING R HOU S B FENG Y YU Q DIONNE-LAPORTE A SAW J H SENIN P WANG W LY B V LEWIS K L T SALZBERG S L FENG L GONES M R SKELTON R L MURRAYJ E CHEN C QIAN W SHEN J DU P EUSTICE M TONG E TANG H LYONS E PAULL R E MICHAEL T P WALL K RICE D W ALBERT H WANG M L ZHU Y J SCHATZ M NAGARAJAN N ACOB R A GUAN P BLAS A WAI C M ACKERMAN C M REN Y LIU C WANG J M WANG J P NA J SHAKIROV E V HAAS B THIMMAPURAM J NELSON D WANG X BOWERS J E GSCHWEND A R DELCHER A L SINGH R SUZUKI J Y TRIPATHI S NEUPANE K WEI H IRIKURA B PAIDI M JIANG N ZHANG W PRESTING G WINDSOR A NAVAJAS-PEREZ R TORRES M J FELTUS A PORTER B LI Y BURROUGHS A M LUO M C LIU L CHRISTOPHER D A MOUNT S M MOORE P H SUGIMURA T JIANG J SCHULER M A FRIEDMAN V MITCHELL-OLDS T SHIPPEN D E PAMPHILIS C W PALMER J D FREELING M PATERSON A H GONSALVES D WANG L ALAM M | 2008 | Nature2008，452，： | 1 |
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