|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Effect of copper on the degradation of pesticides cypermethrin and cyhalothrin显示文摘共存的铜( Cu )的影响在土壤的 pesticidespyrethroid 氯氰菊酯和 cyhalothrin 的降级和在有铜离子的增加的杀虫剂的水系统 werestudied.Serial 集中的相片降级上的离子在 thes 油被刺并且为时间的一个常规时期孵化了,从土壤的摘录的分析用气体色层法( GC )被执行。在水系统的 pyrethroids 的相片降级在紫外照耀下面被进行。杀虫剂降级上的 Cu^(2+) 的效果与降级的半生活(t_(0.5 )) 被测量。在在土壤和 Cu 增加的 pyrethroid 杀虫剂的降级之间的一道负相关被观察,这被发现。但是 Cu^(2+) 能水里的 pyrethroids 的 acceleratephotodegradation。为为氯氰菊酯从 6.7 ~ 6.8 dwhile 扩大的 cyhalothrin 的 t_(0.5 ) 在土壤与铜离子的存在从 8.1 ~ 10.9 d 延长了。作为 forphotodegradation,为 cyhalothrin 的 t_(0.5 ) 从 173.3 ~ 115.5 min 减少了,为到 99.0 min.The 的氯氰菊酯 from115.5,结果建议铜由影响微生物的活动影响了杀虫剂 ins 油的降级。然而,它在水系统有催化剂趋势 forphotodegradation。为在土壤的 pyrethroid 异构体的降级效率的差别也被观察。铜能显然加速一些特殊异构体的降级。 | LIU Ting-feng SUN Cheng TA Na HONG Jun YANG Shao-gui CHEN Chuan-xiang | 2007 | Journal of Environmental Sciences2007，19，10： | 26 |
| 2 | Effects of spironolactone on electrical and structural remodeling of atrium in congestive heart failure dogs显示文摘背景:Renin-angiotensin-aldosterone 系统被表明了与充血心力衰竭(CHF ) 并且在伊朗的银币纤维性颤动(AF ) 被联系。这研究调查了螺内酯的效果,一种醛固酮对手,在上在伊朗的银币,在 CHF 狗的电的改变和纤维变性导致了由长期快速的室的踱步。方法:21 条狗随机被划分成假冒操作组,控制组,和螺内酯组。在控制组和螺内酯组,狗是室的每分钟在 220 敲击踱步 6 个星期。另外,在 15 mg x kg 的螺内酯(-1) x d (-1) 1 个星期在快速的室的踱步前被给狗直到踱步停止了。经胸廓和 transoesophageal echocardiographic 考试被执行检测中庭的结构、功能的变化。Swan2 Ganz 漂浮导管被用来测量缝 adynamics 变化。房的的有效不应期(AERP ) , AERP 分散(AERPd ) , intra 中庭和内部中庭的传导时间(CT ) 和 intra 中庭传导速度(CV ) 是坚定的。AF 的 inducibility 和持续时间也在所有组被测量。最后,在伊朗的银币,纤维变性被确定,马森染色。结果:在狗是室的以后, AERP 没显著地变化踱步 6 个星期。然而,显著地增加的 AERPd, intra 中庭和内部中庭的 CT,和 CV 显然减少了,它否定地被相关到 at 伊朗的银币纤维变性(r =-0.74, P <
0.05 ) 。同时,左中庭被扩大,心脏的缝 adynamics 在在狗上踱步变得更坏。尽管螺内酯不能有效地影响心脏的缝 adynamics,它能显然在伊朗的银币喷射部分改进左(P <
0.05 ) 。螺内酯处理没改变 AERP 持续时间,但是这药戏剧性地减少 AERPd (P <
0.05 ) ,弄短的 intra 中庭和内部中庭的传导时间(P <
0.05 ) ,并且增加的中庭 CV。而且,螺内酯减少了 AF 的 inducibility 和持续时间(P <
0.05 ) ,以及在伊朗的银币,纤维变性(P< 0.01 ) 导致了由长期快速的室的踱步。结论:螺内酯在导致由的充血心力衰竭狗贡献 AF 预防长期快速的室的踱步,它在伊朗的银币纤维变性减小和缝 adynamics 的独立人士与有关。 | YANG Shu-sen HAN Wei ZHOU Hong-yan DONG Guo WANG Bai-chun HUO Hong WEI Na CAO Yong ZHOU Guo XIU Chun-hong LI Wei-min | 2008 | Chinese Medical Journal2008，，1： | 26 |
| 3 | Compensation trends of the angulation of first molars:retrospective study of 1403 malocclusion cases显示文摘We investigated the compensatory trends of mesiodistal angulation of first molars in malocclusion cases. We compared differences in the angulation of first molars in different developmental stages, malocclusion classifications and skeletal patterns. The medical records and lateral cephalogrammes of 1 403 malocclusion cases taken before treatment were measured to evaluate compensation of molar angulation in relation to the skeletal jaw. The cases were stratified by age, Angle classification and skeletal patterns. Differences in the mesiodistal angulation of the first molars were compared among the stratifications. We observed three main phenomena. First,angulation of the upper first molar varied significantly with age and tipped most distally in cases aged,12 years and least distally in cases aged.16 years. The lower first molar did not show such differences. Second, in Angle Class II or skeletal Class II cases, the upper first molar was the most distally tipped, the lower first molar was the most mesially tipped, and opposite angulation compensation was observed in Class III cases. Third, in high-angle cases, the upper and lower first molars were the most distally tipped, and opposite angulation compensation was observed in low-angle cases. These data suggest that the angulation of the molars compensated for various growth patterns and malocclusion types. Hence, awareness of molar angulation compensation would help to adjust occlusal relationships, control anchorage and increase the chances of long-term stability. | Hong Su Bing Han Sa Li Bin Na Wen Ma Tian-Min Xu | 2014 | International Journal of Oral Science2014，6，3： | 22 |
| 4 | Natural history of covert hepatic encephalopathy: An observational study of 366 cirrhotic patients显示文摘AIM To explore the natural history of covert hepatic encephalopathy(CHE) in absence of medication intervention.METHODS Consecutive outpatient cirrhotic patients in a Chinese tertiary care hospital were enrolled and evaluated for CHE diagnosis. They were followed up for a mean of 11.2 ± 1.3 mo. Time to the first cirrhosis-related complications requiring hospitalization, including overt HE(OHE), resolution of CHE and death/transplantation, were compared between CHE and no-CHE patients. Predictors for complication(s) and death/transplantation were also analyzed.RESULTS A total of 366 patients(age: 47.2 ± 8.6 years, male: 73.0%) were enrolled. CHE was identified in 131 patients(35.8%). CHE patients had higher rates of death and incidence of complications requiring hospitalization, including OHE, compared to unimpaired patients. Moreover, 17.6% of CHE patients developed OHE, 42.0% suffered persistent CHE, and 19.8% of CHE spontaneously resolved. In CHE patients, serum albumin < 30 g/L(HR = 5.22, P = 0.03) was the sole predictor for developing OHE, and blood creatinine > 133 μmol/L(HR = 4.75, P = 0.036) predicted mortality. Child-Pugh B/C(HR = 0.084, P < 0.001) and OHE history(HR = 0.15, P = 0.014) were predictors of spontaneous resolution of CHE.CONCLUSION CHE exacerbates, persists or resolves without medication intervention in clinically stable cirrhosis. Triage of patients based on these predictors will allow for more cost-effect management of CHE. | An-Jiang Wang A-Ping Peng Bi-Min Li Na Gan Li Pei Xue-Lian Zheng Jun-Bo Hong Hai-Ying Xiao Jia-Wei Zhong Xuan Zhu | 2017 | World Journal of Gastroenterology2017，23，34： | 22 |
| 5 | Nickel-exposed Workers in China: A Cohort Study显示文摘There are more than 50 000 workers in Jinchuan Group Co,Ltd(JNMC).Since all staff in JNMC are eligible for a medical examination every two years,only 23 484 nickel-exposed subjects who participated in medical examination were included in this study.Their data,collected from June 22,2011 to September 28,2012,in a | BAI Ya Na YAGN Ai Min PU Hong Quan HE Jie CHENG Ning ZHENG Tong Zhang DAI Min ZHANG Ya Wei BASSING Bryan WANG Qiu Ying | 2014 | Biomedical and Environmental Sciences2014，27，3： | 20 |
| 6 | The dynamics of the piglet gut microbiome during the weaning transition in association with health and nutrition显示文摘Background: Understanding the composition of the microbial community and its functional capacity during weaning is important for pig production as bacteria play important roles in the pig's health and growth performance. However,limited information is available regarding the composition and function of the gut microbiome of piglets in early-life.Therefore, we performed 16 S rRNA gene and whole metagenome shotgun sequencing of DNA from fecal samples from healthy piglets during weaning to measure microbiome shifts, and to identify the potential contribution of the early-life microbiota in shaping piglet health with a focus on microbial stress responses, carbohydrate and amino acid metabolism.Results: The analysis of 16 S rR NA genes and whole metagenome shotgun sequencing revealed significant compositional and functional differences between the fecal microbiome in nursing and weaned piglets. The fecal microbiome of the nursing piglets showed higher relative abundance of bacteria in the genus Bacteroides with abundant gene families related to the utilization of lactose and galactose. Prevotel a and Lactobacil us were enriched in weaned piglets with an enrichment for the gene families associated with carbohydrate and amino acid metabolism. In addition, an analysis of the functional capacity of the fecal microbiome showed higher abundances of genes associated with heat shock and oxidative stress in the metagenome of weaned piglets compared to nursing piglets.Conclusions: Overal, our data show that microbial shifts and changes in functional capacities of the piglet fecal microbiome resulted in potential reductions in the effects of stress, including dietary changes that occur during weaning.These results provide us with new insights into the piglet gut microbiome that contributes to the growth of the animal. | Robin B.Guevarra Sang Hyun Hong Jin Ho Cho Bo-Ra Kim Jiwon Shin Jun Hyung Lee Bit Na Kang Young Hwa Kim Suphot Wattanaphansak Richard E.Isaacson Minho Song Hyeun Bum Kim | 2018 | Journal of Animal Science and Biotechnology2018，9，4： | 16 |
| 7 | Peroxisome proliferator-activated receptor-γ is essential in the pathogenesis of gastric carcinoma显示文摘AIM:To investigate whether peroxisome proliferator-activated receptor γ (PPAR-γ) is expressed in human gastric carcinoma and whether PPAR-γ is a potential target for gastric carcinoma therapy.METHODS: PPAR-γ protein in gastric carcinoma was examined by immunohistochemistry. In the gastric carcinoma cell line MGC803, PPAR-γ, survivin, Skp2 and p27 protein and mRNA were examined by Western blotting and real-time reverse transcription-polymerase chain reaction, respectively; proliferation was examined by MTT; apoptosis was examined by chromatin staining with Hoechst 33342 and fluorescence activated cell sorting (FACS). and cell cycle was examined by FACS; the knockdown of PPAR-γ was done by RNA interference.RESULTS: A high level of expression of PPAR-γ was observed in human gastric carcinoma and in a human gastric carcinoma cell line MGC803. The PPAR-γ agonist 15-deoxy-12,14-prostaglandin J2 (15d-PGJ2) inhibited growth, and induced apoptosis and G1/G0 cell cycle arrest in MGC803 cells in a concentration-dependent and time-dependent manner. The effect of 15d-PGJ2 on MGC803 cells was not reversed by the selective and irreversible antagonist GW9662 for PPAR-γ. Furthermore, survivin and Skp2 expression were decreased, whereasp27 expression was enhanced following 15d-PGJ2 treatment in a dose-dependent manner in MGC803 cells. Interestingly, we also found that small interfering RNA for PPAR-γ inhibited growth and induced apoptosis in MGC803 cells. The inhibition of PPAR-γ function may be a potentially important and novel modality for treatment and prevention of gastric carcinoma.CONCLUSION: A PPAR-γ agonist inhibited growth of human gastric carcinoma MGC803 cells by inducing apoptosis and G1/G0 cell cycle arrest with the involvement of survivin, Skp2 and p27 and not via PPAR-γ. | Xiu-Mei Ma Hong Yu Na Huai | 2009 | World Journal of Gastroenterology2009，15，31： | 13 |
| 8 | Serum Uric Acid is Associated with the Predicted Risk of Prevalent Cardiovascular Disease in a Community-dwelling Population without Diabetes显示文摘Objective To examine the association between serum uric acid levels and cardiovascular disease risk among individuals without diabetes. Methods We investigated the association between serum uric acid levels and the risk of prevalent cardiometabolic diseases, 10-year Framingham risk for coronary heart disease, and 10-year risk for atherosclerotic cardiovascular diseases(ASCVD) among 8,252 participants aged ≥ 40 years without diabetes from Jiading district, Shanghai, China. Results Body mass index, waist circumference, blood glucose, glycated hemoglobin, blood pressure, and serum lipids increased progressively across the sex-specific quartiles of uric acid(all P trend < 0.05). Compared with individuals in the lowest quartile, those in the higher quartiles had a significantly higher prevalence of obesity, hypertension, and dyslipidemia(all P trend < 0.05). A fully adjusted logistic regression analysis revealed that individuals in the highest quartile had an increased risk of predicted cardiovascular disease compared with those in the lowest quartile of uric acid. The multivariate adjusted odds ratios(ORs) [95% confidence intervals(CIs)] for the highest quartiles for high Framingham risk were 3.00(2.00-4.50) in men and 2.95(1.08-8.43) in women. The multivariate adjusted ORs(95% CIs) for the highest quartile for high ASCVD risk were 1.93(1.17-3.17) in men and 4.53(2.57-7.98) in women. Conclusion Serum uric acid level is associated with an increased risk of prevalent obesity, hypertension, dyslipidemia, 10-year Framingham risk for coronary heart disease, and 10-year risk for ASCVD among Chinese adults without diabetes. | CHENG Di DU Rui WU Xue Yan LIN Lin PENG Kui MA Li Na XU Yu XU Min CHEN Yu Hong BI Yu Fang WANG Wei Qing DAI Meng LU Jie Li | 2018 | Biomedical and Environmental Sciences2018，31，2： | 13 |
| 9 | Piglets cloned from induced pluripotent stem cells显示文摘 | Nana Fan Jijun Chen Zhouchun Shang Hongwei Dou Guangzhen Ji Qingjian Zou Lu Wu Lixiazi He Fang Wang Kai Liu Na Liu Jianyong Han Qi Zhou Dengke Pan Dongshan Yang Bentian Zhao Zhen Ouyang Zhaoming Liu Yu Zhao Lin Lin Chongming Zhong Quanlei Wang Shouqi Wang Ying Xu Jing Luan Yu Liang Zhenzhen Yang Jing Li Chunxia Lu Gabor Vajta Ziyi Li Hongsheng Ouyang Huayan Wang Yong Wang Yang Yang Zhonghua Liu Hong Wei Zhidong Luan Miguel A Esteban Hongkui Deng Huanming Yang Duanqing Pei Ning Li Gang Pei Lin Liu Yutao Du Lei Xiao Liangxue Lai | 2013 | Cell Research2013，23，1： | 12 |
| 10 | Optimal in vitro culture conditions for murine predominant immature CD8a^+ dendritic cells显示文摘背景使用树枝状的房间(DC2 ) 移植建立的不成熟的 CD8a+ 的前景为在未来的自体免疫的疾病的 immunologic 忍耐和处理是有希望的。然而,为导致 DC2 的方法仍然正在被探索。现在的学习被瞄准调查处于为准备大数字 f 的 vitro 条件最佳从鼠科的骨头髓 cells.Methods 的占优势的 DC2 在不同条件下面有教养的三组骨头髓房间被检验,也就是一个 导致cytokine 的试验性的组( cytokine 组),有刺激因素的granulocyte巨噬细胞殖民地的低集中的一个控制组( GM-CSF ,低 GM-CSF 组)并且没有 ndogenous cytokines 的一个控制组。cytokine 组与 5 ng/ml GM-CSF 是有教养的, 25 ng/ml Fit3 ligand (Flt3L ) , 20 ng/ml interleukin 4 (IL-4 ) 并且 100 ng/ml 干细胞因素(SCF ) 。低 GM-CSF 控制组与 0.4 ng/ml GM-CSF, 25 ng/ml FIt3L 和 100 ng/ml SCF 是有教养的,没有 IL-4。没有 dditional cytokines,没有外长的 cytokines 的控制组是有教养的。所有房间在 5% CO2 下面在 37 点是有教养的。在天 3, 7 和 16, 4 颜色流动 cytometry 被执行分析房间显型,和全部的房间数字被认为分析房间收益。阶段对比显微镜学被用来观察到 cytokine 组更高展出了的房间 morphologies.Results 分配 f 典型不成熟的 CD8a+ DC 特别在白天 3 上,但是全部的房间数字和 DC2 比例在延长文化期间减少了。低 GM-CSF 控制组在天显示出象 cytokine 组的一样的趋势 16 和 22,但是生产更高全部的房间数字(P < 0.05 ) 与更低的 DC2 比例和房间数字。没有外长的 cytokines 的控制组自发地产生了 DC2 的某个比例,但是与低全部的房间和 DC2 数字,那很快减少了,特别在延长文化期间(天 7 和 16 , P < 0.05 ) .Conclusions 文化面对 5 ng/ml GM-CSF , 25 ng/ml Flt3L , 20 ng/ml IL-4 和 100 ng/ml SCF 能很快从鼠科的骨头髓房间导致占优势的不成熟的CD8a+ DC 的大数量。因此,这些为在 vitro 准备鼠科的不成熟的 DC2 代表最佳的文化条件。 | NA Ning XU Lin CAO Kai-yuan LUO Yun YUAN Guang-qing XIANG Peng HONG Liang-qing LI Shu-nong | 2009 | Chinese Medical Journal2009，，3： | 11 |
| 11 | Pyrrolidine dithiocarbamate alleviates the anti-tuberculosis drug-induced liver injury through JAK2/STAT3 signaling pathway:An experimental study显示文摘Objective:To study the effect of pyrrolidine dithiocarbamate(PDTC) on the anti-tuberculosis drug-induced liver injury and the molecular mechanism. Methods:Clean male SD rats were selected as experimental animals and randomly divided into normal group,model group,PDTC group and AG490 group. Animal model of anti-tuberculosis drug-induced liver injury was established by intragastric administration isoniazid + rifampicin. PDTC group received intraperitoneal injection of PDTC,and AG490 group received intraperitoneal injection of AG490. Twenty-eight days after intervention,the rats were executed,and the liver injury indexes,inflammation indexes and oxidative stress indexes in serum as well as JAK2/STAT3 expression,liver injury indexes,inflammation indexes and oxidative stress indexes in liver tissue were determined. Results:p-JAK2,p-STAT3,TNF-α,IL-1β,IL-6,ROS,8-OHdG and MDA expression in liver tissue as well as TBIL,ALT,AST,γ-GT,TNF-α,IL-1β,IL-6,ROS,8-OHdG and MDA levels in serum of model group were significantly higher than those of normal group while p-JAK2,p-STAT3,TNF-α,IL-1β,IL-6,ROS,8-OHdG and MDA expression in liver tissu as well as TBIL,ALT,AST,γ-GT,TNF-α,IL-1β,IL-6,ROS,8-OHdG and MDA levels in serum of PDTC group and AG490 group were significantly lower than those of model group. Conclusions:PDTC can inhibit the inflammation and oxidative stress mediated by JAK2/STAT3 signaling pathway to alleviate the anti-tuberculosis drug-induced liver injury. | Hong Zhang Yang Liu Li-Kun Wang Na Wei | 2017 | Asian Pacific Journal of Tropical Medicine2017，10，5： | 10 |
| 12 | Genetic structure and historical demography of Malus sieversii in the Yili Valley and the western mountains of the Junggar Basin, Xinjiang, China显示文摘Malus sieversii, a wild progenitor of domesticated apple, is distributed in western Xinjiang of China, eastern part of Kazakhstan and Kyrgyzstan in Central Asia. To well understand the genetic structure and the historical demography of this important germplasm resource, we sampled 15 populations with 110 individuals of Malus sieversii from the Yili Valley and the western mountains of the Junggar Basin, Xinjiang, and sequenced two nr DNA fragments for these 110 individuals. Meanwhile, we modeled and compared species distributions under the current and the Last Glacial Maximum climatic conditions. The results showed that populations of M. sieversii from Xinjiang had low levels of genetic diversity and genetic differentiation. During the LGM period, populations of M. sieversii had lost their northern distributions in the western mountains of the Junggar Basin. M. sieversii has experienced a demographic expansion from the south of the Yili Valley to the north of the western mountains of the Junggar Basin during the warm interglacial epochs. Due to the high sensibility of M. sieversii to disturbance, we proposed more attention should be paid to the M. sieversii populations in the western mountains of the Junggar Basin. | Hong Xiang ZHANG Ming Li ZHANG Li Na WANG | 2015 | Journal of Arid Land2015，7，2： | 9 |
| 13 | miR-125a-3p targets MTA1 to suppress NSCLC cell proliferation, migration, and invasion显示文摘联系转移的基因(MTA1 ) 1 在 non-small-cell 肺癌症(NSCLC ) 与房间生长,转移,和幸存被联系。几份以前的报告证明了 microRNAs 通过在他们的种子区域和目标 mRNA 的 3-untranslated 区域之间的相互作用影响基因表示,导致 post-transcriptional 规定。这研究的目的是识别 miRNAs 由指向 MTA1 在 NSCLC 房间压制恶意。在有 MTA1 的 transfection 模仿以后,二根人的 NSCLC 房间线被量的 RT-PCR 并且西方的弄污为 MTA1 的表示分析。酶记者试金被建立测试在 MTA1 和它的在上游的 miRNAs 之间的直接连接。房间增长被 3-(4,5-dimethylthiazol-2-yl ) 估计 -2,5-diphenyltetrazolium 溴化物试金, 5-ethynyl-2-deoxyuridine 分析,和殖民地形成试金。房间移植和侵略能力被愈合创伤的试金和 transwell 试金评估。miRNA/MTA1 轴被量的 RT-PCR 并且从八个 NSCLC 病人的在样品的西方的弄污也探查。在候选人 miRNAs 之中, miR-125a-3p 被显示 post-transcriptionally 在 NSCLC 房间调整 MTA1。这些数据被酶记者试金增强,除了 MTA1 相反地与在 NSCLC 纸巾的 miR-125a-3p 被相关的示范。而且, miR-125a-3p 被发现禁止 NSCLC 房间增长,移植,和侵略,通过下面调整的 MTA1 的一样的机制。我们的报告证明 miR-125a-3p 通过 MTA1 的下面规定禁止 NSCLC 房间的增长,迁居,和侵略,显示在 NSCLC 的 miR-125a-3p/MTA1 轴的角色,并且可以提供新奇卓见进分子的机制 underpinning 疾病和潜在的治疗学的目标。 | Hong Zhang Xiaoxia Zhu Na Li Dianhe Li Zhou Sha Xiaokang Zheng Haofei Wang | 2015 | Acta Biochimica et Biophysica Sinica2015，47，7： | 9 |
| 14 | Effects of trimetazidine on atrial structural remodeling and platelet activation in dogs with atrial fibrillation显示文摘 | HAN Wei LI Wei-min ZHOU Hong-yan HUO Hong WEI Na DONG Guo CAO Yong ZHOU Guo YANG Shu-sen | 2009 | Chinese Medical Journal2009，，18： | 8 |
| 15 | Evaluation of prognostic factors on recurrence after curative resections for hepatocellular carcinoma显示文摘AIM:To select appropriate patients before surgical resection for hepatocellular carcinoma(HCC),especially those with advanced tumors.METHODS:From January 2000 to December 2012,we retrospectively analyzed the medical records of 298 patients who had undergone surgical resections for HCC with curative intent at our hospital.We evaluated preoperative prognostic factors associated with histologic grade of tumor,recurrence and survival,especially the findings of pre-operative imaging studies such as positron emission tomography-computed tomography(PETCT)and magnetic resonance imaging(MRI).And then,we established a scoring system to predict recurrence and survival after surgery dividing the patients into two groups based on a tumor size of 5 cm.RESULTS:Of the 298 patients,129(43.3%)developed recurrence during the follow-up period.The 5 year disease free survival and overall survival were 47.0%and58.7%respectively.In multivariate analysis,a serum alpha-fetoprotein(AFP)level of>100 ng/m L and a standardized uptake value(SUV)of PET-CT of>3.5 were predictive factors for histologic grade of tumor,recurrence,and survival.Tumor size of>5 cm and a relative enhancement ratio(RER)calculated from preoperative MRI were also significantly associated with prognosis in univariate analysis.We established a scoring system to predict prognosis using AFP,SUV,and RER.In those with tumors of>5 cm,it showed predicted both recurrence(P=0.005)and survival(P=0.001).CONCLUSION:The AFP,tumor size,SUV and RER are useful for prognosis preoperatively.An accurate prediction of prognosis is possible using our scoring system in large size tumors. | Jae Hyun Han Dong Goo Kim Gun Hyung Na Eun Young Kim Soo Ho Lee Tae Ho Hong Young Kyoung You | 2014 | World Journal of Gastroenterology2014，20，45： | 8 |
| 16 | Relationship between Maternal PBMC HBV cccDNA and HBV Serological Markers and its Effect on HBV Intrauterine Transmission显示文摘Objective To investigate the relationship between maternal peripheral blood mononuclear cells (PBMC) hepatitis B virus(HBV) covalenty closed circular deoxyribonucleic acid(cccDNA) and other HBV serological markers and its effects on HBV intrauterine transmission. Methods We enrolled 290 newborns and their hepatitis B surface antigen(HBsAg) positive mothers. HBV cccDNA in PBMC and HBV DNA in serum were detected by a real‐time PCR‐TaqM an probe while HBV serological markers were detected with an electrochemiluminescence immunoassay. Results There was a positive correlation between the levels of PBMC HBV cccD NA and serum HBV DNA and HBeA g(r = 0.436 and 0.403, P < 0.001). The detection rate of pattern A [‘HBsA g(+), HBeA g(+), and anti‐HBc(+)’] was significantly higher in the PBMC HBV cccD NA positive group than in the control group(χ^2 = 48.48, P < 0.001). There was a significant association between HBV intrauterine transmission and PBMC HBV cccD NA(χ^2 = 9.28, P = 0.002). In the presence of serum HBV DNA, HBeA g, and PBMC HBV cccD NA, the risk of HBV intrauterine transmission was three times higher(OR = 3.69, 95% CI: 1.30‐10.42) than that observed in their absence. The risk of HBV intrauterine transmission was the greatest(OR = 5.89, 95% CI: 2.35‐14.72) when both PBMC HBV cccD NA and pattern A were present. A Bayesian network model showed that maternal PBMC HBV cccD NA was directly related to HBV intrauterine transmission. Conclusion PBMC HBV cccDNA may be a direct risk factor for HBV intrauterine transmission. Our study suggests that serological markers could be combined with PBMC‐related markers in prenatal testing. | WANG Dan Dan YI Lin Zhu WU Li Na YANG Zhi Qing HAO Hai Yun SHI Xiao Hong WANG Bo FENG Shu Ying FENG Yong Liang WANG Su Ping | 2019 | Biomedical and Environmental Sciences2019，32，5： | 8 |
| 17 | Five-year major clinical outcomes between first-generation ana second- generation drug-eluting stents in acute myocardial infarction patients underwent percutaneous coronary intervention显示文摘 | Yong Hoon Kim Ae-Young Her Seung-Woon Rha Byoung Geol Choi Se Yeon Choi Jae Kyeong Byun Ju Yeol Baek Woong Gil Choi Tae Soo Kang Ji Hoon Ahn Sang-Ho Park Ahmed Mashaly Jin Oh Na Cheol Ung Choi Hong Euy Lim Eung Ju Kim Chang Gyu Park Hong Seog Seo Dong Joo Oh | 2018 | Journal of Geriatric Cardiology2018，15，8： | 8 |
| 18 | Association of Overlapped and Un-overlapped Comorbidities with COVID-19 Severity and Treatment Outcomes: A Retrospective Cohort Study from Nine Provinces in China显示文摘Objective Several COVID-19 patients have overlapping comorbidities. The independent role of each component contributing to the risk of COVID-19 is unknown, and how some non-cardiometabolic comorbidities affect the risk of COVID-19 remains unclear.Methods A retrospective follow-up design was adopted. A total of 1,160 laboratory-confirmed patients were enrolled from nine provinces in China. Data on comorbidities were obtained from the patients’ medical records. Multivariable logistic regression models were used to estimate the odds ratio(OR) and 95% confidence interval(95% CI) of the associations between comorbidities(cardiometabolic or non-cardiometabolic diseases), clinical severity, and treatment outcomes of COVID-19.Results Overall, 158(13.6%) patients were diagnosed with severe illness and 32(2.7%) had unfavorable outcomes. Hypertension(2.87, 1.30–6.32), type 2 diabetes(T2 DM)(3.57, 2.32–5.49),cardiovascular disease(CVD)(3.78, 1.81–7.89), fatty liver disease(7.53, 1.96–28.96), hyperlipidemia(2.15, 1.26–3.67), other lung diseases(6.00, 3.01–11.96), and electrolyte imbalance(10.40, 3.00–26.10)were independently linked to increased odds of being severely ill. T2 DM(6.07, 2.89–12.75), CVD(8.47,6.03–11.89), and electrolyte imbalance(19.44, 11.47–32.96) were also strong predictors of unfavorable outcomes. Women with comorbidities were more likely to have severe disease on admission(5.46,3.25–9.19), while men with comorbidities were more likely to have unfavorable treatment outcomes(6.58, 1.46–29.64) within two weeks.Conclusion Besides hypertension, diabetes, and CVD, fatty liver disease, hyperlipidemia, other lung diseases, and electrolyte imbalance were independent risk factors for COVID-19 severity and poor treatment outcome. Women with comorbidities were more likely to have severe disease, while men with comorbidities were more likely to have unfavorable treatment outcomes. | MA Yan ZHU Dong Shan CHEN Ren Bo SHI Nan Nan LIU Si Hong FAN Yi Pin WU Gui Hui YANG Pu Ye BAI Jiang Feng CHEN Hong CHEN Li Ying FENG Qiao GUO Tuan Mao HOU Yong HU Gui Fen HU Xiao Mei HU Yun Hong HUANG Jin HUANG Qiu Hua HUANG Shao Zhen JI Liang JIN Hai Hao LEI Xiao LI Chun Yan LI Min Qing LI Qun Tang LI Xian Yong LIU Hong De LIU Jin Ping LIU Zhang MA Yu Ting MAO Ya MO Liu Fen NA Hui WANG Jing Wei SONG Fang Li SUN Sheng WANG Dong Ting WANG Ming Xuan WANG Xiao Yan WANG Yin Zhen WANG Yu Dong WU Wei WU Lan Ping XIAO Yan Hua XIE Hai Jun XU Hong Ming XU Shou Fang XUE Rui Xia YANG Chun YANG Kai Jun YUAN Sheng Li ZHANG Gong Qi ZHANG Jin Bo ZHANG Lin Song ZHAO Shu Sen ZHAO Wan Ying ZHENG Kai ZHOU Ying Chun ZHU Jun Teng ZHU Tian Qing ZHANG Hua Min WANG Yan Ping WANG Yong Yan 无 | 2020 | Biomedical and Environmental Sciences2020，33，12： | 8 |
| 19 | High performance Aurivillius type Na_(0.5)Bi_(4.5)Ti_(4)O_(15) piezoelectric ceramics with neodymium and cerium modification显示文摘Bismuth layer-structured ferroelectric ceramics of Na0.5Bi4.5-x(Nd_(0.5)Ce_(0.5)))xTi4O15(NBT-x,0.0≤x≤0.4)were synthesized by a traditional solid-state reaction.The effect of(Nd,Ce)substitution for A-site on the microstructure and electrical properties of Na_(0.5)Bi_(4.5)Ti_(4)O_(15)(NBT)-based piezoelectric ceramics was investigated.X-ray diffraction(XRD)analysis revealed that the(Nd,Ce)-modified NBT ceramics have a pure four-layer Aurivillius type structure.The piezoelectric properties of NBT ceramics were significantly improved by the modification of neodymium and cerium.The Curie temperature TC gradually decreased from 638℃to 618℃with increasing the(Nd,Ce)modification.The piezoelectric constant d33,mechanical quality factor Qm,dielectric loss tanδand Curie temperature TC of the Na0.5Bi4.3(Nd_(0.5)Ce_(0.5)))0.2Ti4O15 ceramic were found to be 28 pC/N,3239,0.0032 and 630℃,respectively.Thermal annealing studies indicated that the(Nd,Ce)-modified NBT ceramics possess stable piezoelectric properties,demonstrating that the Na0.5Bi4.3(Nd_(0.5)Ce_(0.5)))0.2Ti4O15 ceramic is a promising candidate for high temperature applications. | Xiang-Ping JIANG Xiao-Long FU Chao CHEN Na TU Ming-Zhu XU Xiao-Hong LI Hong SHAO Yun-Jing CHEN | 2015 | Journal of Advanced Ceramics2015，4，1： | 8 |
| 20 | Lee discrepancy on asymmetrical factorials with two-and three-levels显示文摘Lee discrepancy has been employed to measure the uniformity of fractional factorials.In this paper,we further study the statistical justification of Lee discrepancy on asymmetrical factorials.We will give an expression of the Lee discrepancy of asymmetrical factorials with two-and three-levels in terms of quadric form,present a connection between Lee discrepancy,orthogonality and minimum moment aberration,and obtain a lower bound of Lee discrepancy of asymmetrical factorials with two-and three-levels. | CHATTERJEE Kashinath QIN Hong ZOU Na | 2012 | Science China Mathematics2012，55，3： | 7 |
您所在的机构暂未开通此部分的功能，请联系管理员