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| 1 | Association of ezrin expression in intestinal and diffuse gastric carcinoma with clinicopathological parameters and tumor type显示文摘AIM: To investigate the correlation between ezrin expression and types of gastric carcinoma and clinicopathological variables. METHODS: We examined ezrin protein expression in 75 gastric carcinoma (53 intestinal types of adenocarcinoma, 22 diffuse types of carcinoma) tissues by immunohistochemistry. The results were compared with clinicopathological parameters such as tumor type, grade of tumor, clinical stage, presence of metastatic lymph node, and depth of invasion. RESULTS: Ezrin immunostaining was positive in 43 cases (81.1%) of intestinal type and in 9 (40.9%) cases of diffuse type adenocarcinomas (P < 0.001). In gastric carcinomas, the expression of ezrin protein correlated with the status of H pylori and survival. There was no correlation between expression of ezrin with TNM stage and histological grade of gastric carcinomas (P > 0.05). CONCLUSION: The low expression of ezrin implicates the loss of adhesion in diffuse carcinomas. Furthermore, overexpression of ezrin in carcinomas with H pylori infection may be a genuine specific pathway in which H pylori may cause/initiate gastric carcinoma. | Nebil Bal Sedat Yildirim Tarik Z Nursal Filiz Bolat Fazilet Kayaseluk | 2007 | World Journal of Gastroenterology2007，13，27： | 9 |
| 2 | Recurrent ischemic stroke as an initial manifestation of an concealed pancreatic adenocarcinoma: Trousseau's syndrome显示文摘在稀罕例子,摸可以 preceed 癌症的诊断并且是 malignancy.Cerebral 梗塞主要复杂化淋巴瘤,癌,和稳固的肿瘤的位于 \O 下面的第一条临床的证据。恶意相关的 thromboembolism 能介绍同样尖锐的服的梗塞, nonbacterial thrombotic 心内膜炎和迁移的 thrombophlebitis。它通常被归因于一个癌症相关的 hypercoagulable 时期,长期的 dissemiated intravascular coagulopathy (DIC ) ,或肿瘤栓塞。我们从 undiagnosed 报导了 malignancy-releated thromboembolism 的一个案例在由于长期的 DIC 与周期性的 ischemic 击介绍了的一个 54 岁的人的胰腺的腺癌。尽管有 anticoagulation therapy.This 大小写的适当机构,他死于内在的恶意强调服的梗塞可以是 undiagnosed 癌症的第一表明。如果有实验室或临床的证据,与 DIC 联系,有未知病原学的服的梗塞的病人应该为一个恶意的过程被调查。在有 thromboembolic 疾病的癌症病人的 anticoagulation 的最佳的方法(晒) 仍然保持不清楚。 | Semih Giray Feyzi Birol Sarica Zulfikar Arlier Nebil Bal | 2011 | Chinese Medical Journal2011，，4： | 4 |
| 3 | Comparison of the inhibitory effect of different doses of subconjunctival bevacizumab application in an experimental model of corneal neovascularization显示文摘● AIM: To evaluate the inhibitory effect of subconjunctival bevacizumab as single-and multiple-dose application, and compare their effects on corneal neovascularization in a rat model.● METHODS: Thirty adult Sprague-Dawley rats were used in this experimental study. The central cornea of the rats was cauterized chemically. The rats were randomly enrolled into three groups. All groups received subconjunctival injections. In Group 1(control group, n=10), 0.05 m L 0.9% Na Cl solution was injected on the first day. In Group 2(single-dose group, n=10), 0.05 m L bevacizumab(1.25 mg) was injected on the first day. In Group 3(multiple-dose group, n=10), four doses of 0.05 m L bevacizumab(1.25 mg) were injected on the first, third, fifth and seventh day. Slit-lamp examination of all rats was performed at the third and ninth day. Digital images of the corneas were taken and analyzed using image analysis software to calculate corneal neovascularization area. All rats were sacrificed on the tenth day. In corneal sections, the number of blood vessels, state of inflammation and collagen formation was evaluated histopathologically.● RESULTS: In Group 3, corneal edema grades were significantly lower than Group 1 and Group 2(P=0.02, and P=0.035, respectively). The mean percentage of neovascularized corneal area in Group 3 was significantly lower than Group 2(P=0.005). On histopathological examination, Group 2 and Group 3 showed significantly less number of blood vessels than Group 1(P=0.005, and P=0.001, respectively). Additionally, Group 3 showed significantly less number of blood vessels compared to Group 2(P=0.019). Inflammation and edema grades were significantly lower in Group 3 compared to Group 1(P=0.001).● CONCLUSION: Subconjunctival bevacizumab injection is effective in inhibition of newly formed corneal neovascularization. The multiple-dose bevacizumab treatment seems to be more effective compared to single-dose treatment. | Burak Ulas Rana Altan-Yaycioglu Nebil Bal | 2018 | International Journal of Ophthalmology(English edition)2018，11，7： | 3 |
| 4 | Nasolacrimal Duct Obstruction: Clinicopathologic Analysis of 205 Cases显示文摘 | Rana Altan-Yaycioglu Handan Canan Selcuk Sizmaz Nebil Bal Aysel Pelit Yonca A. Akova | 2010 | Orbit2010，，5： | 1 |
| 5 | Vulvar syringoma aggravated by pregnancy显示文摘 | Nebil Bal Erdogan Aslan Fazilet Kayasel?uk Ebru Tarim Ilhan Tuncer | 2003 | Pathology Oncology Research2003，，3： | 1 |
| 6 | Computed tomographic findings of trichuriasis显示文摘在这份报告,我们结肠的鞭虫病的现在的计算 tomographic 调查结果。病人是抱怨了腹的疼痛,和重量损失的一个 75 岁的人。诊断被 colonoscopic 活体检视完成。不规则、榴状的显示出的腹的计算断层摄影术盲肠和上升冒号的墙变厚。尽管这些调查结果是非特定的,他们可以是鞭虫病的调查结果之一。这些调查结果,由 biopsied 织物和 Kato-Katz 寄生物学的的凳子筹款技术的病理学的分析证实了,揭示成年鞭虫属。到我们的知识,这是计算断层摄影术显示的结肠的鞭虫病的第一份报告。 | Naime Tokmak Zafer Koc Serife Ulusan Ismail Soner Koltas Nebil Bal | 2006 | World Journal of Gastroenterology2006，12，26： | 0 |
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