|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Triggered instability of liposomes bound to hydrophobically modified core-shell PNIPAM hydrogel beads显示文摘 | MacKinnon Neil Guerin Gerald Liu Baoxu | 2010 | Langmuir2010，26，2： | 1 |
| 2 | Galectin-3 Expression and Secretion Links Macrophages to the Promotion of Renal Fibrosis显示文摘 | Neil C. Henderson Alison C. Mackinnon Sarah L. Farnworth Tiina Kipari Christopher Haslett John P. Iredale Fu-Tong Liu Jeremy Hughes Tariq Sethi | 2008 | The American Journal of Pathology2008，，2： | 1 |
| 3 | Laser-induced hierarchical carbon patterns on polyimide substrates for flexible urea sensors显示文摘Thermochemical decomposition of organic materials under heat-treatment in the absence of oxygen,known as the pyrolysis process,is often employed to convert micro and nano patterned polymers into carbon structures,which are subsequently used as device components.Pyrolysis is performed at≥900℃,which entails substrate materials with a high thermal stability that excludes flexible,polymeric substrates.We use optimized laser radiation to pattern graphitic carbon structures onto commercially available polyimide(Kapton)sheets in the micrometer to millimeter scale by inducing a localized,rapid pyrolysis,for the fabrication of flexible devices.Resulting laser carbon films are electrically conductive and exhibit a high-surface area with a hierarchical porosity distribution along their cross-section.The material is obtained using various combinations of laser parameters and pyrolysis environment(oxygen-containing and inert).Extensive characterization of laser carbon is performed to understand the correlation between the material properties and laser parameters,primarily fluence and power.A photothermal carbonization mechanism based on the plume formation is proposed.Further,laser carbon is used for the fabrication of enzymatic,pH-based urea sensors using two approaches:(i)direct urease enzyme immobilization onto carbon and(ii)electrodeposition of an intermediate chitosan layer prior to urease immobilization.This flexible sensor is tested for quantitative urea detection down to 10^(−4) M concentrations,while a qualitative,color-indicative test is performed on a folded sensor placed inside a tube to demonstrate its compatibility with catheters.Laser carbon is suitable for a variety of other flexible electronics and sensors,can be conveniently integrated with an external circuitry,heating elements,and with other microfabrication techniques such as fluidic platforms. | Emil R.Mamleyev Stefan Heissler Alexei Nefedov Peter G.Weidler Nurdiana Nordin Vladislav V.Kudryashov Kerstin Länge Neil MacKinnon Swati Sharma | 2019 | npj Flexible Electronics2019，3，1： | 0 |
| 4 | Narrative minireview of the spatial epidemiology of substance use disorder in the United States:Who is at risk and where?显示文摘Drug overdose is the leading cause of death by injury in the United States.The incidence of substance use disorder(SUD)in the United States has increased steadily over the past two decades,becoming a major public health problem for the country.The drivers of the SUD epidemic in the United States have changed over time,characterized by an initial heroin outbreak between 1970 and 1999,followed by a painkiller outbreak,and finally by an ongoing synthetic opioid outbreak.The nature and sources of these abused substances reveal striking differences in the socioeconomic and behavioral factors that shape the drug epidemic.Moreover,the geospatial distribution of the SUD epidemic is not homogeneous.The United States has specific locations where vulnerable communities at high risk of SUD are concentrated,reaffirming the multifactorial socioeconomic nature of this epidemic.A better understanding of the SUD epidemic under a spatial epidemiology framework is necessary to determine the factors that have shaped its spread and how these patterns can be used to predict new outbreaks and create effective mitigation policies.This narrative minireview summarizes the current records of the spatial distribution of the SUD epidemic in the United States across different periods,revealing some spatiotemporal patterns that have preceded the occurrence of outbreaks.By analyzing the epidemic of SUD-related deaths,we also describe the epidemic behavior in areas with high incidence of cases.Finally,we describe public health interventions that can be effective for demographic groups,and we discuss future challenges in the study and control of the SUD epidemic in the country. | Diego F Cuadros Adam J Branscum Claudia M Moreno Neil J MacKinnon | 2023 | World Journal of Clinical Cases2023，11，11： | 0 |
| 5 | Integrated impedance sensing of liquid sample plug flow enables automated high throughput NMR spectroscopy显示文摘A novel approach for automated high throughput NMR spectroscopy with improved mass-sensitivity is accomplished by integrating microfluidic technologies and micro-NMR resonators.A flow system is utilized to transport a sample of interest from outside the NMR magnet through the NMR detector,circumventing the relatively vast dead volume in the supplying tube by loading a series of individual sample plugs separated by an immiscible fluid.This dual-phase flow demands a real-time robust sensing system to track the sample position and velocities and synchronize the NMR acquisition.In this contribution,we describe an NMR probe head that possesses a microfluidic system featuring:(i)a micro saddle coil for NMR spectroscopy and(ii)a pair of interdigitated capacitive sensors flanking the NMR detector for continuous position and velocity monitoring of the plugs with respect to the NMR detector.The system was successfully tested for automating flow-based measurement in a 500 MHz NMR system,enabling high resolution spectroscopy and NMR sensitivity of 2.18 nmol s1/2 with the flow sensors in operation.The flow sensors featured sensitivity to an absolute difference of 0.2 in relative permittivity,enabling distinction between most common solvents.It was demonstrated that a fully automated NMR measurement of nine individual 120μL samples could be done within 3.6 min or effectively 15.3 s per sample. | Omar Nassar Mazin Jouda Michael Rapp Dario Mager Jan G.Korvink Neil MacKinnon | 2021 | Microsystems & Nanoengineering2021，7，2： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员