|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Effects of different levels of urea supplementation on nutrient intake and growth performance in growing camels fed roughage based complete pellet diets显示文摘The utilization of urea in camels has beneficial and negative effects. The aims of this study were to investigate the effects of different levels of urea supplementation on nutrients intake, digestibility,growth performance, feed efficiency and economics in growing camels fed roughage based complete pellet diets. In the present study, eighteen growing camels with an average live body weight of306.17 ± 2.05 kg were randomly assigned in three treatments: T1 = roughage complete pellet diet without urea,T2 = T1 plus 1% urea,and T3 = T1 plus 2% urea. The results showed that the urea supplementation significantly affected average daily feed and nutrient intake of dry matter(DM), organic matter(OM), crude protein(CP), neutral detergent fiber(NDF), and acid detergent fiber(ADF)(P < 0.05).On the contrary, the average daily intake of nitrogen free extract(NFE) and water were not influenced by increasing urea supplementation(P > 0.05). Similarly, digestion coefficient of DM, CP, ether extract(EE),crude fiber(CF) and ADF was influenced by increasing urea level(P < 0.05), while the digestion coefficient of OM, NFE and NDF was not affected by increasing urea level(P > 0.05). The intake of digestive nutrients was similar among all treatment groups. Total body live weight gain and average daily gain were significantly higher in urea supplemented groups(P < 0.05) than in the control group. The supplementation of urea at 1% in low quality roughage complete pellet diets significantly improved(P < 0.05) the feed efficiency. In conclusion,these results indicated that the incorporation of urea at 1% in roughage based complete pellet diets could positively improve nutrients intake, digestibility, growth performance and feed conversion efficiency of growing camels. | Ntiranyibagira Emmanuel Niteen V.Patil Shekbar R.Bhagwat Abdul Lateef Kang Xu Hongnan Liu | 2015 | Animal Nutrition2015，，4： | 6 |
| 2 | Haemoxygenase modulates cytokine induced neutrophil chemoattractant in hepatic ischemia reperfusion injury显示文摘AIM To investigate the hepatic microcirculatory changes due to Haemoxygenase(HO),effect of HO inhibition on remote ischemic preconditioning(RIPC) and modulation of CINC.METHODS Eight groups of animals were studied- Sham,ischemia reperfusion injury(IRI) the animals were subjected to 45 min of hepatic ischemia followed by three hours of reperfusion,RIPC(remote ischemic preconditioning) + IRI group,remote ischemic preconditioning in sham(RIPC + Sham),PDTC + IR(Pyridodithiocarbamate,HO donor),Zn PP + RIPC + IRI(Zinc protoporphyrin prior to preconditioning),IR-24(45 min of ischemia followed by 24 h of reperfusion),RIPC+IR-24(preconditioning prior to. After 3 and 24 h of reperfusion the animals were killed by exsanguination and samples were taken. RESULTS Velocity of flow(160.83 ± 12.24 μm/s),sinusoidal flow(8.42 ± 1.19) and sinusoidal perfusion index(42.12 ± 7.28) in hepatic IR were lower(P < 0.05) in comparison to RIPC and PDTC(HO inducer). RIPC increased velocity of flow(328.04 ± 19.13 μm/s),sinusoidal flow(17.75 ± 2.59) and the sinusoidal perfusion index(67.28 ± 1.82)(P < 0.05). PDTC(HO induction) reproduced the effects of RIPC in hepatic IR. PDTC restored RBC velocity(300.88 ± 22.109 μm/s),sinusoidal flow(17.66 ± 3.71) and sinusoidal perfusion(82.33 ± 3.5) to near sham levels. Zn PP(HO inhibition) reduced velocity of flow of RBC in the RIPC group(170.74 ± 13.43 μm/s and sinusoidal flow in the RIPC group(9.46 ± 1.34). Zn PP in RIPC(60.29 ± 1.82) showed a fall in perfusion only at 180 min of reperfusion. Neutrophil adhesion in IR injury is seen in both postsinusoidal venules(769.05 ± 87.48) and sinusoids(97.4 ± 7.49). Neutrophil adhesion in RIPC + IR injury is reduced in both postsinusoidal venules(219.66 ± 93.79) and sinusoids(25.69 ± 9.08)(P < 0.05). PDTC reduced neutrophil adhesion in both postsinusoidal venules(89.58 ± 58.32) and sinusoids(17.98 ± 11.01)(P < 0.05) reproducing the effects of RIPC. Zn PP(HO inhibition) increased venular(589.04 ± 144.36) and sinusoidal neutrophil adhesion in preconditioned animals(121.39 ± 30.65)(P < 0.05). IR after 24 h of reperfusion increased venular and sinusoidal neutrophil adhesion in comparison to the early phase and was significantly reduced by RIPC. Hepatocellular cell death in IRI(80.83 ± 13.03),RIPC + IR(17.35 ± 2.47),and PTDC+IR(11.66 ± 1.17) Zn PP + RIPC + IR(41.33 ± 3.07) reduced hepatocellular death. Zn PP significantly increased hepatocellular death(P < 0.05 PTDC/RIPC vs Zn PP and IR). The CINC cytokine levels in sham(101.32 ± 6.42). RIPC + sham(412.18 ± 65.24) as compared to sham(P < 0.05). Hepatic IR(644.08 ± 181.24)(P < 0.05). RIPC CINC-1 levels in the early phase(401.62 ± 78.56). And PDTC(HO inducer) CINC-1 levels in hepatic IR(413.36 ± 63.06) were significantly lower. HO inhibition in preconditioned animals with Zinc protoporphyrin increased serum CINC levels(521.81 ± 74.9)(P < 0.05). The serum CINC levels were high in the late phase of hepatic IR(15306 ± 1222.04). RIPC reduced CINC levels in the late phase of IR(467.46 ± 26.06),P < 0.05.CONCLUSION RIPC protects hepatic microcirculation by induction of HO and modulation of CINC in hepatic IR. | Niteen Tapuria Sameer Junnarkar Mahmoud Abu-amara Barry Fuller Alexander M Seifalian Brian R Davidson | 2016 | World Journal of Gastroenterology2016，22，33： | 3 |
| 3 | Liver Isehemia/Reperfusion Injury: Processes in Inflammatory Net- works- A Review 显示文摘 | Mahmoud Abu-Amara Shi Yu Yang Niteen Tapuria | 2010 | Liver Transplantation2010，16，： | 1 |
| 4 | LiverIschemia/Reperfusion Injury : Processes in Inflammatory Networks-A Review显示文摘 | Mahmoud Abu - Amara Shi Yu Yang Niteen Tapuria | 2010 | Liver Transplantation2010，16，： | 1 |
| 5 | Effect of remote ischemic preconditioning on liver ischemia/reperfusion injury using a new mouse model显示文摘 | Mahmoud Abu‐Amara Shi Yu Yang Alberto Quaglia Peter Rowley Niteen Tapuria Alexander M. Seifalian Barry J. Fuller Brian R. Davidson | 2011 | Liver Transpl2011，，1： | 1 |
| 6 | Remote Ischemic Preconditioning: A Novel Protective Method From Ischemia Reperfusion Injury—A Review显示文摘 | Niteen Tapuria Yogesh Kumar Meer Mohammad Habib Mahmoud Abu Amara Alexander M. Seifalian Brian R. Davidson | 2008 | Journal of Surgical Research2008，，2： | 1 |
| 7 | Remote Ischemic Preconditioning: A Novel Protective Method From Ischemia Reperfusion Injury—A Review显示文摘 | Niteen Tapuria Yogesh Kumar Meer Mohammad Habib Mahmoud Abu Amara Alexander M. Seifalian Brian R. Davidson | 2008 | Journal of Surgical Research2008，，2： | 1 |
| 8 | The baculovirus antiapoptotic p35 gene also functions via anoxidant-dependent pathway显示文摘 | NAND K SAH TARVINDER K NITEEN PATHAK | 1999 | PNAS1999，96，： | 1 |
| 9 | Remote ischemic precondi-tioning:A novel protective method from ischemia reperfusion inju-ry a review显示文摘 | Niteen T Yogesh K Meer MH | 2008 | J Surgical Res2008，150，2： | 1 |
| 10 | Safety and efficacy of Bivalirudin with Glycoprotein IIb/IIIa for high-risk percutaneous coronary intervention显示文摘 | Niteen V. Deshpande Rebecca Pratiti Parag Admane Debabrata Mukherjee Harshawardhan M. Mardikar | 2012 | Indian Heart Journal2012，，5： | 1 |
| 11 | General-motors diet: A quick fix for steatotic live liver donors显示文摘Background and aims:GM(General-Motors)diet is a low-calorie 7-day diet plan using complex carbohydrates used for quick weight loss.Dietary optimisation is known to decrease steatosis and improve outcomes in liver donors.We evaluated the efficacy and feasibility of using GM diet in steatotic live liver donors(LLD).Methods:LLDs who either had BMI>30 kg/m^(2),Computerised tomography liver attenuation index(CT-LAI)<0 HU,Magnetic resonance(MR)fat-fraction of>10%were started on GM diet for 1 week.Records of these LLDs and their recipients were retrieved retrospectively and analysed.Weight,liver function tests(LFT),MR fat-frac-tion,CT-LAI,hospital-stay and complications were analysed in LLDs while early graft dysfunction(EGD)and complications were assessed in recipients.Results:A total of 51 LLDs with mean age of 34.6?9.5 years with baseline mean weight of 80.6±10.8 kg and BMI of 29.1±2.78 kg/m^(2) were started on GM diet.After a week of following the GM diet,there was an average weight loss of 3.46±2.1 kg,a decrease in fat-fraction by 3.8%±2.7,and an improvement in CT-LAI by 6.7?3.7 HU.All patients could successfully undergo donor hepatectomy with an average postoperative ICU stay of 2.86±0.8 days and hospital stay of 6.82?0.81 days.No donor had steatosis>10% on intraoperative Tru-cut biopsy and their post-operative outcomes were similar to normal liver donors.There were intra-abdominal collections in 2 donors requiring drainage and one required re-exploration for intestinal obstruction.There was EGD in 8 recipients(15.6%)and mortality in 1(1.9%)recipients.Conclusion:GM diet is safe and effective regimen to reduce steatosis and increase healthy LLD pool without compromising donor or recipient safety. | Anish Gupta Abhideep Chaudhary Gaurav Sood Niteen Kumar Imtiakum Jamir Aditya Shriya Vipin Pal Singh Rekha Subramaniyam Hitesh Soni Milind Mandwar | 2023 | iLIVER2023，2，3： | 0 |
| 12 | Impact of Living Donor Liver Transplantation on COVID-19 Clinical Outcomes from a Quaternary Care Centre in Delhi显示文摘Background and Aims:The anticipated fear of serious out-comes in coronavirus infected liver transplant recipients led to disruption of transplant services globally.The aim of our study was to analyze COVID-19 severity in transplant recipients and to compare the difference of COVID-19 clinical outcomes in early(<1 year)vs.late(>1 year)post-transplant period.Methods:41 post-living donor liver transplant recipients with COVID-19 infection were studied retrospectively from 1st April 2020 to 28th February 2021.Results:The median age was 49.00 years with a male preponderance(80.49%).Fif-teen patients had infection within 1 year of transplant and 26 were infected after 1 year of transplant.The overall median interval between transplantation and COVID-19 diagnosis was 816.00 days.Fever and malaise were the common presenting symptoms.The most common associated comorbidities were diabetes mellitus(65.85%)and hypertension(46.34%).The severity of illness was mild in 28(68.29%),moderate in 4(9.76%),severe in 6(14.63%)and critical in 3(7.32%).To identify associated risk factors,we divided our patients into less severe and more severe groups.Except for lymphopenia,there was no worsening of total bilirubin,transaminases,al-kaline phosphatase,and gamma-glutamyl transferase in the more severe group.Eight(19.51%)patients required inten-sive care unit admission and three(7.32%)died,while none suffered graft rejection.In recipients with early vs.late post-transplant COVID-19 infection,there were similar outcomes in terms of severity of COVID-19 illness,intensive care unit care need,requirement of respiratory support,and death.Conclusion:Living donor liver transplantation can be per-formed during the COVID-19 pandemic without the fear of poor recipient outcome in cases of unfortunate contraction of severe acute respiratory syndrome coronavirus-2. | Imtiakum Jamir Niteen Kumar Gaurav Sood Ashish George Pankaj Lohia Samba Siva Rao Pasupuleti Amrish Sahney Manav Wadhawan Ajay Kumar Abhideep Chaudhary | 2022 | Journal of Clinical and Translational Hepatology2022，10，4： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员