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| 1 | Trans-arterial chemoperfusion for the treatment of liver metastases of breast cancer and colorectal cancer: Clinical results in palliative care patients显示文摘AIM To evaluate the clinical value and efficiency of transarterial chemoperfusion(TACP) in patients with liver metastases from breast cancer(BC) and colorectal cancer(CRC).METHODS We treated 36 patients with liver metastases of BC(n = 19, 19 females) and CRC(n = 17; 8 females, 9 males) with repeated TACP. The treatment interval was 4 wk. TACP was performed with gemcitabine(1000 mg/m2) and mitomycin(10 mg/m2), administered within 1 h after positioning the catheter tip in the hepatic artery. Before treatment, the size, location, tumour volume, vascularization and number of liver tumours were evaluated using magnetic resonance imaging(MRI). Tumour response was evaluated according to the Response Evaluation Criteria in Solid Tumors guidelines.RESULTS TACP using gemcitabine and mitomycin for metastases from CRC and BC was performed without any serious side effects. The follow-up MRI showed a therapeutic response in 84.2% of the BC patients-stable disease 47.4% and partial response 36.8%. A progression was seen in 15.8%.CRC patients showed a therapeutic response in 52.9% of cases. A progression of the disease was documented in 47.1% of the patients with CRC. These data show that TACP in patients with liver metastases of BC leads to a significantly better therapeutic response compared with CRC patients(P = 0.042). The median survival time was 13.2 mo for the BC patients, which is significantly longer than for CRC patients at 9.3 mo(P = 0.001).CONCLUSION TACP for liver metastases of BC appears to be a safe and effective palliative treatment with improved outcomes in comparison to patients with CRC. | Tatjana Gruber-Rouh Marcel Langenbach Nagy NN Naguib Nour-Eldin M Nour-Eldin Thomas J Vogl Stephan Zangos Martin Beeres | 2017 | World Journal of Clinical Oncology2017，8，4： | 7 |
| 2 | Intrauterine device use and some issues related to sexually transmitted disease screening and occur- fence 显示文摘 | Hodoglugil NN Asian D Bertan M | 2000 | Contraception2000，61，6： | 1 |
| 3 | Incidence and types of childhood exolropia: a population_based study显示文摘 | Govindan M Mohney BC Diehl NN | 2005 | Ophthalmology2005，112，： | 1 |
| 4 | Antitumor beta glucan from the cultured fruit body of Agaricus blazei显示文摘 | Ohno N Furukawa M Miura NN | 2001 | Biol Pharm Bull2001，24，7： | 1 |
| 5 | Traumaic rupture of the diaphragm显示文摘 | Cubukcu A Paksoy M Gonullu NN | 2000 | Int J Clin Pract2000，54，1： | 1 |
| 6 | Randomized clinicaltrial of stapler versus clamp-crushing transection in elec-tive liver resection显示文摘 | Rahbari NN Elbers H Koch M | 2014 | Br J Surg2014，101，3： | 1 |
| 7 | Structure of Atg5 center dot Atg16, a complex essential for autophagy 显示文摘 | Furuya M Suzuki NN Obara K | 2007 | J Biol Chem2007，282，6： | 1 |
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| 9 | Acupuncture and exercise restore adipose tissue expression of sympathetic markers and improve ovarian morphology in rats with dihydrotestosteroneinduced PCOS显示文摘 | Manner(a)s L Cajander S L(o)nn M | | 0，，： | 1 |
| 10 | Traumatic rupture of the diaphragm显示文摘 | Cubukcu A Paksoy M Gonullu NN | 2000 | Int j Clin Pract2000，54，1： | 1 |
| 11 | Rigid endoscopic evaluation of canventional curettage adenoidectomy显示文摘 | Regmi D Mathur NN Bhattarai M | 2011 | ijournal of laryngology and otology2011，125，1： | 1 |
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| 14 | Identificaiton of an estrogen response element activated by metabolites of 17β-estrodiol and raloxifene显示文摘 | Yang NN Venugopalan M Hardikar S | 1996 | Science1996，273，： | 1 |
| 15 | Bacillus Calmette-Guerin, Mycobacterium bovis, as an immunomodulator in atopic diseases 显示文摘 | Barlan I Bahceciler NN Akdis M | 2006 | Immunol Allergy Clin North Am2006，26，2： | 1 |
| 16 | Meta analysis shows that detection of circulating tumor cells indicates poor progno sis in patients with coloreetal cancer 显示文摘 | Rahhari NN Aigner M Thorlund K | 2010 | Gastroenterology2010，138，5： | 1 |
| 17 | Incidence and types of childhood extropia:A population-based study显示文摘 | Govindan M Mohney BG Diehl NN | 2005 | Ophthalmology2005，112，1： | 1 |
| 18 | Cardiac function and electrical remodeling of the calcineurin-overexpressed transgenie mouse显示文摘 | Petrashevskaya NN Bodi I Rubio M | 2002 | Cardiovasc Res2002，54，1： | 1 |
| 19 | Osteointegration of bioactive glass-coated and uncoated zirconia in osteopenic bone:an in vivo experimental study显示文摘 | Aldini NN Fini M Giavaresi G | | 0，，02： | 1 |
| 20 | Antioxidant activity of the cruciferous vegetable Maca (Lepidium meyenii) 显示文摘 | SANDOVAL M OKUHAMA NN ANGELES FM | 2002 | Food Chemistry2002，79，： | 1 |
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