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| 1 | Incidence and risk factors for early renal dysfunction after liver transplantation显示文摘AIM: To determine renal dysfunction post liver transplantation, its incidence and risk factors in patients from a Belgian University Hospital.METHODS: Orthotopic liver transplantations performed from January 2006 until September 2012 were retrospectively reviewed(n = 187). Patients with no renal replacement therapy(RRT) before transplantation were classified into four groups according to their highest creatinine plasma level during the first postoperative week. The first group had a peak creatinine level below 12 mg/L, the second group between 12 and 20 mg/L, the third group between 20 and 35 mg/L, and the fourth above 35 mg/L. In addition, patients who needed RRT during the first week after transplantation were also classified into the fourth group. Perioperative parameters were recorded as risk factors, namely age, sex, bodymass index(BMI), length of preoperative hospital stay, prior bacterial infection within one month, preoperative ascites, preoperative treatment with β-blocker, angiotensin-converting enzyme inhibitor or non steroidal anti-inflammatory drugs, preoperative creatinine and bilirubin levels, donor status(cardiac death or brain death), postoperative lactate level, need for intraoperative vasopressive drugs, surgical revision, mechanical ventilation for more than 24 h, postoperative bilirubin and transaminase peak levels, postoperative hemoglobin level, amount of perioperative blood transfusions and type of immunosuppression. Univariate and multivariate analysis were performed using logistic ordinal regression method. Post hoc analysis of the hemostatic agent used was also done.RESULTS: There were 78 patients in group 1(41.7%), 46 in group 2(24.6%), 38 in group 3(20.3%) and 25 in group 4(13.4%). Twenty patients required RRT: 13(7%) during the first week after transplantation. Using univariate analysis, the severity of renal dysfunction was correlated with presence of ascites and prior bacterial infection, preoperative bilirubin, urea and creatinine level, need for surgical revision, use of vasopressor, postoperative mechanical ventilation, postoperative bilirubin and urea, aspartate aminotransferase(ASAT), and hemoglobin levels and the need for transfusion. The multivariate analysis showed that BMI(OR = 1.1, P = 0.004), preoperative creatinine level(OR = 11.1, P < 0.0001), use of vasopressor(OR = 3.31, P = 0.0002), maximal postoperative bilirubin level(OR = 1.44, P = 0.044) and minimal postoperative hemoglobin level(OR = 0.059, P = 0.0005) were independent predictors of early post-liver transplantation renal dysfunction. Neither donor status nor ASAT levels had significant impact on early postoperative renal dysfunction in multivariate analysis. Absence of renal dysfunction(group 1) was also predicted by the intraoperative hemostatic agent used, independently of the extent of bleeding and of the preoperative creatinine level.CONCLUSION: More than half of receivers experienced some degree of early renal dysfunction after liver transplantation. Main predictors were preoperative renal dysfunction, postoperative anemia and vasopressor requirement. | Patricia Wiesen Paul B Massion Jean Joris Olivier Detry Pierre Damas | 2016 | World Journal of Transplantation2016，6，1： | 9 |
| 2 | Early plasmapheresis and rituximab for acute humoral rejection after ABO-compatible liver transplantation显示文摘Acute humoral rejection (AHR) is uncommon after ABO-compatible liver transplantation. Herein, we report two cases of AHR treated with plasmapheresis and rituximab in two ABO-compatible liver-transplant patients with preformed anti-human leukocyte antigen donor-specif ic antibodies. Patient 1 experienced a biopsy-proven AHR at day 10 post-transplant. She was treated by steroid pulses, and OKT3. Because of persisting signs of biopsy-proven AHR at day 26, she was treated by plasmapheresis and rituximab. Liver enzyme levels did not improve, and she died on day 41. Patient 2 experienced a biopsy-proven AHR on day 10 post-transplant. She was treated by steroid pulses, plasmapheresis, and rituximab. Liver enzymes returned to within normal range 18 d after diagnosis. Liver biopsies, at 3 and 9 mo post-transplant, showed complete resolution of AHR. We conclude that plasmapheresis should be started as soon as AHR is diagnosed, and be associated with a B-cell depleting agent. Rituximab may be considered as a first-line therapy. | Nassim Kamar Laurence Lavayssière Fabrice Muscari Janick Selves Céline Guilbeau-Frugier Isabelle Cardeau Laure Esposito Olivier Cointault Marie Béatrice Nogier Jean Marie Peron Philippe Otal Marylise Fort Lionel Rostaing | 2009 | World Journal of Gastroenterology2009，15，27： | 6 |
| 3 | Meeting report:a hard look at the state of enamel research显示文摘The Encouraging Novel Amelogenesis Models and Ex vivo cell Lines(ENAMEL) Development workshop was held on 23 June 2017 at the Bethesda headquarters of the National Institute of Dental and Craniofacial Research(NIDCR). Discussion topics included model organisms, stem cells/cell lines, and tissues/3 D cell culture/organoids. Scientists from a number of disciplines,representing institutions from across the United States, gathered to discuss advances in our understanding of enamel, as well as future directions for the field. | ophir d klein olivier duverger wendy shaw rodrigo s lacruz derk joester janet moradian-oldak megan k pugach j timothy wright sarah e millar ashok b kulkarni john d bartlett thomas gh diekwisch pamela den besten james p simmer | 2017 | International Journal of Oral Science2017，9，4： | 3 |
| 4 | A new Upper Carboniferous stem-orthopteran (Insecta) from Ningxia (China)显示文摘 | Olivier Béthoux Jun-Jie Gu Dong Ren | 2012 | Insect Science2012，19，2： | 2 |
| 5 | Laparoscopic left lateral resection is the gold standard for benign liver lesions: a case–control study显示文摘 | Safi Dokmak Vikram Raut Béatrice Aussilhou Fadhel Samir Ftériche Olivier Farges Alain Sauvanet Jacques Belghiti | 2014 | HPB2014，，2： | 2 |
| 6 | Effect of SSRI antidepressants on ejaculation:a double-blind,randomized,placebo-controlled study with fluoxetine,fluvoxamine,paroxetine,and sertraline显示文摘 | Waldinger MD Hengeveld MW Zwinderman AH Olivier B | 1998 | Clin Psychopharmacol1998，8，4： | 1 |
| 7 | Cloning and mapping of variety-speeific rice genomic DNA sequences:amplifled fragment length polymorphisms(AFLP)from silver-stained Polyaerylamide gels显示文摘 | Yong G C MattheW w B OliVier P et a1 | 1996 | Genome1996，39，： | 1 |
| 8 | Adenovirusmediated Gene Transfer Endoststin in Vivo Resalts in Hihg Level of Transgene Expression and Inhibition of Tumor Growth and Metastases显示文摘 | Sauter B C Olivier M Zhang W Z | 2000 | Proc Natl Acad USA2000，97，： | 1 |
| 9 | Intracellular Pool of Vascular Endothelial Growth Factor in Human Neutrophils显示文摘 | Murielle G Olivier B Valérie A | 1997 | Blood1997，90，10： | 1 |
| 10 | Dietary fibre and fibre-rich by-products of food processing:Characterisation,technological functionality and commercial applications:A review显示文摘 | Mohamed E A Dorothea B B Olivier R C | | 0，，02： | 1 |
| 11 | Morphology, origin and infrared microthermometry of fluid inclusions in pyrite from the Radka epithermal copper deposit, Srednogorie zone, Bulgaria显示文摘 | Kalin Kouzmanov Laurent Bailly Claire Ramboz Olivier Rouer Jean-Michel Bény | 2002 | Mineralium Deposita (-)2002，，6： | 1 |
| 12 | Simulation of wheels in nonlinear, flexible multibody Systems显示文摘 | Olivier A B Jesus R | 2002 | Multibody System Dynamics2002，4，17： | 1 |
| 13 | Proposal for a definition of lifelong premature ejaculation based on epidemiological stopwatch data显示文摘 | Waldinger MD Zwinderman AH Olivier B | 2005 | J Sex Med2005，2，4： | 1 |
| 14 | 显示文摘 | Hocher B Godes M Olivier J | 2002 | J Hypertens2002，20，4： | 1 |
| 15 | Ionic liquids and catalysis: Recent progress from knowledge to applica- tions显示文摘 | OLIVIER B H MAGNA L MORVAN D | 2010 | Applied Catalysis A: General2010，373，12： | 1 |
| 16 | Weather index insurance for agriculture and rural areas in lower-income countries 显示文摘 | Barry J B Olivier M | 2007 | American Journal of Agricultural Economics2007，89，5： | 1 |
| 17 | Effect of SSRIantipressant on ejaculation: a double-blind, randomized, placebo-controlled study with floxetine, flovuxamlne, paroxetine, and sertraline 显示文摘 | WALDINGER MD HENGEVELD MW OLIVIER B | 1998 | J Clin Psychopharmacol1998，18，4： | 1 |
| 18 | Thalidomide in systemic mastocytosis: results from an open‐label, multicentre, phase II study显示文摘 | Bérengère Gruson Olivier Lortholary Danielle Canioni Olivia Chandesris Fanny Lanternier Julie Bruneau Bernard Grosbois Cristina Livideanu Claire Larroche Isabelle Durieu Stéphane Barete Henri Sevestre Momar Diouf Guillaume Chaby Jean‐Pierre Marolleau Patr | 2013 | Br J Haematol2013，，3： | 1 |
| 19 | Aggregation of 3,5-dihydroxybenzyl alcohol based dendrimers and hyperbranched polymers, and encapsulation of DR1 in such dendritic aggregates显示文摘 | Olivier B Jared B Rami H | 2004 | Inorg Chim Acta2004，357，13： | 1 |
| 20 | Resistance to a drug blocking human immunodeficiency virus type 1 entry (RPR103611) is conferred by mutations in gp41显示文摘 | Béatrice Labrosse Olivier Pleskoff Nathalie Sol | 1997 | Journal of virology1997，71，11： | 1 |
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