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| 1 | JAK-STAT pathway in carcinogenesis:Is it relevant to cholangiocarcinoma progression?显示文摘The features of JAK-STAT signaling in liver cells are discussed in the current review. The role of this signaling cascade in carcinogenesis is accentuated. The possible involvement of this pathway and alteration of its elements are compared for normal cholangiocytes, cholangiocarcinoma predisposition and development. Prolactin and interleukin-6 are described in detail as the best studied examples. In addition, the non-classical nuclear translocation of cytokine receptors is discussed in terms of its possible implication to cholangiocarcinoma development. | Olga V Smirnova Tatiana Yu Ostroukhova Roman L Bogorad | 2007 | World Journal of Gastroenterology2007，13，48： | 14 |
| 2 | Contribution of functional KIR3DL1 to ankylosing spondylitis显示文摘Increasing evidence points to a role for killer immunoglobulin-like receptors(KIRs)in the development of autoimmune diseases.In particular,a positive association of KIR3DS1(activating receptor)and a negative association of KIR3DL1(inhibitory receptor)alleles with ankylosing spondylitis(AS)have been reported by several groups.However,none of the studies analyzed these associations in the context of functionality of polymorphic KIR3DL1.To better understand how the KIR3DL1/3DS1 genes determine susceptibility to AS,we analyzed the frequencies of alleles and genotypes encoding functional(KIR3DL1*F)and non-functional(KIR3DL1*004)receptors.We genotyped 83 AS patients and 107 human leukocyte antigen(HLA)-B27-positive healthy controls from the Russian Caucasian population using a two-stage sequence-specific primer PCR,which distinguishes KIR3DS1,KIR3DL1*F and KIR3DL1*004 alleles.For the patients carrying two functional KIR3DL1 alleles,those alleles were additionally genotyped to identify KIR3DL1*005 and KIR3DL1*007 alleles,which are functional but are expressed at low levels.KIR3DL1 was negatively associated with AS at the expense of KIR3DL1*F but not of KIR3DL1*004.This finding indicates that the inhibitory KIR3DL1 receptor protects against the development of AS and is not simply a passive counterpart of the segregating KIR3DS1 allele encoding the activating receptor.However,analysis of genotype frequencies indicates that the presence of KIR3DS1 is a more important factor for AS susceptibility than the absence of KIR3DL1*F.The activation of either natural killer(NK)or T cells via the KIR3DS1 receptor can be one of the critical events in AS development,while the presence of the functional KIR3DL1 receptor has a protective effect.Nevertheless,even individuals with a genotype that carried two inhibitory KIR3DL1 alleles expressed at high levels could develop AS. | Ivan V Zvyagin Ilgar Z Mamedov Olga V Britanova Dmitriy B Staroverov Evgeni L Nasonov Anna G Bochkova Anna V Chkalina Alexei A Kotlobay Dmitriy O Korostin Denis V Rebrikov Sergey Lukyanov Yuri B Lebedev Dmitriy M Chudakov | 2010 | Cellular & Molecular Immunology2010，7，6： | 5 |
| 3 | Isoflavonoid accumulation in soybean hairy roots upon treatment with Fusarium solani显示文摘 | Vera V L Anatoliy V L Olga V Z | 2004 | Plant Physiology and Biochemistry2004，42，8： | 1 |
| 4 | Genome rearrangements, deletions, and amplifications in the natural population of Bartonella henselae 显示文摘 | HILLEVI L OLGA V ALEX M | 2006 | Journal of Bacteriology2006，188，21： | 1 |
| 5 | Absorption anisotropy studies of polymethine dyes显示文摘 | RICHARD S L CLAUDIU M C OLGA V P | 2004 | Chemical Physics2004，306，13： | 1 |
| 6 | A coupled analysisof experimental and theoretical results on the deformationand failure of composite laminates under a state of planestress 显示文摘 | Peter A Z Olga V L Ludmilla P T | 2002 | Composites Science and Technology2002，62，： | 1 |
| 7 | Automatic clustering and boundary detection algorithm based on adaptive influence function 显示文摘 | Gleb V Dongquan L Olga S | 2008 | Pat- tern Recognition Accepted Manuscript2008，，3： | 1 |
| 8 | Two types of hydropbo- bic aggregates in aqueous solutions of chitosan and its hydrophobic derivative 显示文摘 | OLGA E P EVGENII V V NATALIA L | 2001 | Biomacromolecules2001，2，3： | 1 |
| 9 | The effect of caffeic acid phenethyl ester analogues in a modified resistant hepatocyte model显示文摘 | José R. Macías-Pérez Olga Beltrán-Ramírez Verónica R. Vásquez-Garzón Martha E. Salcido-Neyoy Pablo A. Martínez-Soriano Mónica B. Ruiz-Sánchez Enrique ángeles Saúl Villa-Trevi?o | 2013 | Anti-Cancer Drugs2013，，4： | 1 |
| 10 | Laboratory diagnosis of human neurocysticercosis: double-blind comparison of enzyme-Linked immunosorbent assay and electroimmunotransfer Blot Assay 显示文摘 | Proao-Narvaez J V Antonio M L Olga M R | 2002 | J Clin Microbiol2002，40，6： | 1 |
| 11 | Molecular evidence of a new strain of Ehrlichia canis from South America显示文摘 | Javier V Olga L Arnaldo A | 2007 | J Clini Microbiol2007，45，8： | 1 |
| 12 | Identification of rifampin-resi- stant mycobacterium tuberculosis strains by hybridization,PCR, and ligase detection reaction on oligonucleotide microchips显示文摘 | Vladimir M Sergey L Dimitry G Alexander S Boris S Nikolai C Olga S Olga I Arkadii M Vitalii L Mikhall V Mikhail P Larisa C Vladislav E Alexander Z Andrei M | 2001 | Journal of Clinical Microbiology2001，39，7： | 1 |
| 13 | Dramatic Changes in the Prevalence of Helicobacter pylori Infection During Childhood: A 10-year Follow-up Study in Russia显示文摘 | Mikhail A Tkachenko Nurgalieva Z Zhannat Lev V Erman Elena L Blashenkova Sergey V Isachenko Olga B Isachenko David Y Graham Hoda M Malaty | 2007 | Journal of Pediatric Gastroenterology and Nutrition2007，，4： | 1 |
| 14 | Excited state absorption dynamics in polymethinc dyes detected by polarization resolved pump probe measurements 显示文摘 | RICHARD S L OLGA V P JOEL M H | 2003 | Chemical Physics2003，286，23： | 1 |
| 15 | Identification of rifampin-resi-stant mycobacterium tuberculosis strains by hybridization,PCR,and ligase detection reaction on oligonucleotide microchips显示文摘 | Vladimir M Sergey L Dimitry G Alexander S Boris S Nikolai C Olga S Olga I Arkadii M Vitalii L Mikhall V Mikhail P Larisa C Vladislav E Alexander Z Andrei M | 2001 | Journal of Clinical Microbiology2001，，39： | 1 |
| 16 | Electrochemical performance of Klason lignin as a low-cost cathode-active material for primary lithium battery显示文摘A few classes of organic compounds are promising electrode-active materials due to their high power and energy densities,low cost,environmental friendliness,and functionality.In the present work,the possibility of using Klason lignin extracted from buckwheat husks as a cathode-active material for a primary lithium battery has been investigated for the first time.The reaction mechanism in the lithium/lignin electrochemical cell was suggested based on the deep galvanostatic discharge(up to 0.005 V) data and cyclic voltammetry results.The dependence of the electrochemical behavior of the Klason lignin on the milling degree was evaluated.The maximum specific capacity of the lignin is equal to 600 m Ah g-1at a discharge current density of 75 μA cm-2.Beneficial effect of the thermal treatment of the Klason lignin cathode at250°C on the cell performance was established.It was found that the discharge capacity of the cell increased by 30% in the range from 3.3 to0.9 V for the treated cathode material.These results demonstrate the prospects of using Klason lignin-based electrochemical cells as low-rate primary power sources. | Sergey V Gnedenkov Denis P Opra Ludmila A Zemnukhova Sergey L Sinebryukhov Iliya A Kedrinskii Olga V Patrusheva Valentin I Sergienko | 2015 | Journal of Energy Chemistry2015，24，3： | 0 |
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