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| 1 | Large-Scale Analyses of Glycosylation in Cellulases显示文摘Cellulases are important glycosyl hydrolases (GHs) that hydrolyze cellulose polymers into smaller oligosaccharides by breaking the cellulose β (1→4) bonds,and they are widely used to produce cellulosic ethanol from the plant biomass.N-linked and O-linked glycosylations were proposed to impact the catalytic efficiency,cellulose binding affinity and the stability of cellulases based on observations of individual cellulases.As far as we know,there has not been any systematic analysis of the distributions of N-linked and O-linked glycosylated residues in cellulases,mainly due to the limited annotations of the relevant functional domains and the glycosylated residues.We have computationally annotated the functional domains and glycosylated residues in cellulases,and conducted a systematic analysis of the distributions of the N-linked and O-linked glycosylated residues in these enzymes.Many N-linked glycosylated residues were known to be in the GH domains of cellulases,but they are there probably just by chance,since the GH domain usually occupies more than half of the sequence length of a cellulase.Our analysis indicates that the O-linked glycosylated residues are significantly enriched in the linker regions between the carbohydrate binding module (CBM) domains and GH domains of cellulases.Possible mechanisms are discussed. | Fengfeng Zhou Victor Olman Ying Xu | 2009 | Genomics, Proteomics & Bioinformatics2009，7，4： | 3 |
| 2 | A segmentation algorithm for noisy images: design and evaluation显示文摘 | Xu Y Olman V Edward C U | 1998 | Pattern Recognition Letters1998，19，13： | 1 |
| 3 | Changes in procoagulant and fibrinolytic gene expression during blemycininduced lung injury in the mouse显示文摘 | Olman MA Iackman N Gladson CL | 1995 | J Clin Invest1995，96，3： | 1 |
| 4 | Clustering gene expression data using a graph-theoretic approach:an application of minimum spanning trees显示文摘 | Xu Y Olman V Xu D | 2002 | Bioinformatics2002，18，4： | 1 |
| 5 | Microarry analysis indicates that pulmonary edema fluid from patients with acute lung injury mediates inflammation, mitogen gene expression, and fibroblast proliferation through bioactive interleukin-1显示文摘 | Olman MA White KE Ware LB | 2002 | Chest2002，121，3： | 1 |
| 6 | Clustering gene expression data using a graph-theoretic approach: an application of minimum span- ning trees显示文摘 | Xu Y Olman V Xu D | 2002 | Bioinformatics2002，18，4： | 1 |
| 7 | Fibrin fragment induction of plasminogen activator inhibitor transcription is mediated by activator protein-1 through a highly conserved element显示文摘 | Olman MA Hagood JS Simmons WL | 1999 | Blood1999，94，6： | 1 |
| 8 | Clustefing gene expression data using a graph-theoretic approach:application of minimum spanning trees显示文摘 | Xu V Olman D Xu | 2002 | Bioinformatics2002，18，4： | 1 |
| 9 | Biologic markers of mortality in acute lung in- jury显示文摘 | Gaggar A Olman MA | 2006 | Clin Chim Acta2006，372，12： | 1 |
| 10 | Chronic pulmonarythromboembolism in dogs treated with tranexamic acid显示文摘 | Moser KM Cantor JP Olman M | 1991 | Circulation1991，83，4： | 1 |
| 11 | EXCAVATOR:a computer program for efficiently mining gene expression data显示文摘 | Xu D Olman V Wang L | 2003 | Nucleic Acids Research2003，31，19： | 1 |
| 12 | Minimum Spanning Trees for Gene Expression Data Clustering 显示文摘 | Xu Y Olman V Xu D | 2001 | Genome Informatics (S0919-9454)2001，11，12： | 1 |
| 13 | CXCIA2-mediated induction of plasminogen activator inhibitor-1 expression in human CXCR4 positive astroglioma cells显示文摘 | Oh JW Olman M Benveniste EN | 2009 | Biol Pharm Bull2009，32，： | 1 |
| 14 | Retinotopie mapping with spin echo BOLD at 7 T 显示文摘 | OLMAN C A VAN DE MOORTELE P F SCHUMACHER J F | 2010 | Magn Reson Imaging2010，28，9： | 1 |
| 15 | Changes in procoagulant and fibrinolytic gene expression during bleomycin-induced lung injury in the mouse显示文摘 | Olman MA Mackman N Gladson CL | 1995 | J Clin Invest1995，96，： | 1 |
| 16 | Downregulation of FAK-related non-kinase mediates the migratory phenotype of human fibrotic lung fibroblasts显示文摘 | Guo-qiang Cai Anni Zheng Qingjiu Tang Eric S. White Chu-Fang Chou Candece L. Gladson Mitchell A. Olman Qiang Ding | 2010 | Experimental Cell Research2010，，： | 1 |
| 17 | A segmentation algorithm for noisy images: design and evaluation 显示文摘 | Ying Xu Victor Olman Histon Smith | 1998 | Pattern Recognition Letters1998，19，13： | 1 |
| 18 | Chronic pulmonary thromboembolism in dogs treated with tranexamic acid 显示文摘 | Moser KM Cantor JP Olman M | 1991 | Circulation1991，83，4： | 1 |
| 19 | Beyond TGF-beta: a prostaglandin promotes fibrosis 显示文摘 | Olman M A | 2009 | Nat Med2009，15，12： | 1 |
| 20 | Changes in procoaglant and fibrinolytic gene expression during Bleomycin-induced lung in the mouse显示文摘 | Olman M A Nigel Mackman | 1995 | J Clin Invest1995，96，： | 1 |
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