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| 1 | Noninvasive assessment of liver damage in chronic hepatitis B显示文摘AIM:To evaluate the efficacy of the aspartate aminotransferase/platelet ratio index(APRI)and neutrophillymphocyte(N/L)ratio to predict liver damage in chronic hepatitis B(CHB).METHODS:We analyzed 89 patients diagnosed with CHB by percutaneous liver biopsy and 43 healthy subjects.Liver biopsy materials were stained with hematoxylin-eosin and Masson’s trichrome.Patients’fibrosis scores and histological activity index(HAI)were calculated according to the Ishak scoring system.Fibrosis score was recognized as follows:F0-1 No/early-stage fibrosis,F2-6 significant fibrosis,F0-4 non-cirrhotic and F5-6 cirrhotic.Significant liver fibrosis was defined as an Ishak score of≥2.APRI and N/L ratio calculation was made by blood test results.RESULTS:The hepatitis B and control group showed no difference in N/L ratios while there was a significant difference in terms of APRI scores(P<0.001).Multiple logistic regression analysis revealed that the only independent predictive factor for liver fibrosis in CHB was platelet count.APRI score was significantly higher in cirrhotic patients than in non-cirrhotic patients.However,this significance was not confirmed by multiple logistic regression analysis.The optimum APRI score cut-off point to identify patients with cirrhosis was 1.01with sensitivity,specificity,positive predictive value and negative predictive value of 62%(36%-86%),74%(62%-83%),29%(13%-49%)and 92%(82%-97%),respectively.In addition,correlation analyses revealed that N/L ratio has a negative and significant relationship with HAI(r=-0.218,P=0.041).CONCLUSION:N/L ratio was negatively correlated with HAI.APRI score may be useful to exclude cirrhosis in CHB patients. | Mehmet Celikbilek Serkan Dogan Sebnem Gursoy Gokmen Zararsιz Alper Yurci Omer Ozbakιr Kadri Guven Mehmet Yucesoy | 2013 | World Journal of Hepatology2013,5,8: | 5 |
| 2 | Dissolved organic carbon (DOC) as a parameter of compost maturity显示文摘 | Sharon Z N Omer M Jorge T | 2005 | Soil Biology & Biochemistry2005,,37: | 1 |
| 3 | Efficacy of insulin-sensitizing agents in nonalcoholic fatty liver disease显示文摘 | Omer Z Cetinkalp S Akyildiz M | | 0,,01: | 1 |
| 4 | Plant colonization by pink-pigmented facultative methylotrophic bacteria (PPFMs) 显示文摘 | Omer Z S Tombolini R Gerhardson B | 2004 | FEMS Microbiology Ecology2004,47,3: | 1 |
| 5 | Dissolved organic carbon (DOC) as a pa- rameter of compost maturity显示文摘 | Sharon Z Omer M Jorge T | 2005 | Soil Biology & Biochemistry2005,2,: | 1 |
| 6 | Continuous airborne communication relay approach using unmanned aerial vehicles 显示文摘 | OMER C IBRAHIM Z | 2012 | Journal of Intelligent & Robotic Systems2012,65,1: | 1 |
| 7 | Dissolved organic carbon (DOC) as a parameter of compost maturity显示文摘 | Sharon Z Omer M Jorge T | 2005 | Soil Biology & Biochemistry2005,37,11: | 1 |
| 8 | A userfriendly fuzzy-based system for the selection of electro discharge machining process parameters显示文摘 | Oguzhan Yilmaz Omer Eyercioglu Nabil N Z Gindy | 2006 | Joumal of Materials Processing Technology2006,172,: | 1 |
| 9 | Dissolved organic carbon(DOC) as a parameter of compost maturity显示文摘 | SHARON Z N OMER M JORGE T | 2005 | SoilBiology and Biochemistry2005,37,: | 1 |
| 10 | Dissolved organic carbon(DOC) as a parameter of compost maturity 显示文摘 | Sharon Z Omer M Jorge T | 2005 | Soil Biology Biochemistry2005,37,11: | 1 |
| 11 | 查看详情显示文摘 | Ursin R Tiefenbacher E Schmitt M T Weier H Scheidl T Lin-denthal M Blauensteiner B Jennewein T Perdigues J Trojek E Omer B Fu st M Meyenburg M Rarity J Sodnik Z Barbieri C Weinfurter H Zeilinger A | | 0,,: | 1 |
| 12 | Dissolved organic carbon(DOC) as a parameter of compost maturity显示文摘 | Sharon Z Omer M Jorge T | 2005 | Soil Biology & Biochemistry2005,2,: | 1 |
| 13 | Efficacy of insulinsensitizing agents in nonalcoholic fatty liver diseases显示文摘 | Omer Z Cetinkalp S Akyildiz M | 2010 | European Journal of Gastroenterology and Hepatology2010,22,: | 1 |
| 14 | Efficacy of insu- lin-sensitizing agents in nonalcoholic fatty liver disease 显示文摘 | Omer Z Cetinkalp S Akyildiz M | 2010 | Eur J Gastroenterol Hepatol2010,22,1: | 1 |
| 15 | Edge stress intensity functions in 3D anisotropic composites显示文摘 | YOSIBASH Z OMER N DAUGE M | 2008 | Composites Science and Technology2008,68,5: | 1 |
| 16 | Efficacy of insulin- sensitizing agents in nonalcoholic fatty liver disease显示文摘 | Omer Z Cetinkalp S Akyildiz M | 2010 | Eur J Gastroenterol Hepatol2010,22,: | 1 |
| 17 | Efficacy of insulin - sensitizing agents in nonalcoholic fatty liver disease显示文摘 | OMER Z CETINKALP S AKYILDIZ M | 2010 | EurJ Gastroenterol Hepatol2010,22,1: | 1 |
| 18 | DNA polymerase cooperates with polymerasesKandLin translesion DNA synthesis across pyrimidine photodimers in ceils from XPV patients显示文摘 | Omer Z Nicholas G Satoshi N | 2009 | PNAS2009,106,11: | 1 |
| 19 | Growth hormone deficiency is associated with decreased quality of life in patients with prior acromegaly显示文摘 | Wexler T Gunnell L Omer Z | 2009 | J Clin Endocrinol Metab2009,94,7: | 1 |
| 20 | Accelerated corneal crosslinking concurrent with laser in situ keratomileusis显示文摘 | H. Ugur Celik Nese Alag?z Yusuf Yildirim Alper Agca John Marshall Ahmet Demirok Omer Faruk Yilmaz | 2012 | Journal of Cataract & Refractive Surgery2012,,8: | 1 |