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| 1 | Factor analysis identifies subgroups of constipation显示文摘AIM:To determine whether distinct symptom groupings exist in a constipated population and whether such grouping might correlate with quantifiable pathophysiological measures of colonic dysfunction.METHODS:One hundred and ninety-one patients presenting to a Gastroenterology clinic with constipation and 32 constipated patients responding to a newspaper advertisement completed a 53-item,wide-ranging selfreport questionnaire.One hundred of these patients had colonic transit measured scintigraphically.Factor analysis determined whether constipation-related symptoms grouped into distinct aspects of symptomatology.Cluster analysis was used to determine whether indi-vidual patients naturally group into distinct subtypes.RESULTS:Cluster analysis yielded a 4 cluster solution with the presence or absence of pain and laxative unresponsiveness providing the main descriptors.Amongst all clusters there was a considerable proportion of patients with demonstrable delayed colon transit,irritable bowel syndrome positive criteria and regular stool frequency.The majority of patients with these characteristics also reported regular laxative use.CONCLUSION:Factor analysis identified four constipation subgroups,based on severity and laxative unresponsiveness,in a constipated population.However,clear stratification into clinically identifiable groups remains imprecise. | Philip G Dinning Mike Jones Linda Hunt Sergio E Fuentealba Jamshid Kalanter Denis W King David Z Lubowski Nicholas J Talley Ian J Cook | 2011 | World Journal of Gastroenterology2011，17，11： | 3 |
| 2 | Read-write Holographic Memory with Iron-doped Lithium Niobate 显示文摘 | Philips W | 1976 | Ferroelectrics1976，11，： | 1 |
| 3 | Metabolic syndrome and its components as predictors of incident type 2 diabetes mellitus in an Aboriginal community显示文摘 | Ley Sylvia H Harris Stewart B Mamakeesick Mary Noon Tina Fiddler Edith Gittelsohn Joel Wolever Thomas M S Connelly Philip W Hegele Robert A Zinman Bernard Hanley Anthony J G | 2009 | Canadian Medical Association. Journal2009，，6： | 1 |
| 4 | Static Response of Stranded Wire Helical Springs 显示文摘 | Costello G A Philips J W | 1979 | International Journal of Mechanical Science1979，21，： | 1 |
| 5 | Interferomctric signals in fiber optic methane sensors with wavelength modulation of the DFB laser source 显示文摘 | Stewart G Mcncaglia A Philip W Jin W | 1998 | Journal of Ligluwave Technology1998，16，： | 1 |
| 6 | Cardic function before and after surgery for pectus excavatum显示文摘 | Warren G Guntheroth W G Philip S | 2007 | Am J Cardio12007，99，12： | 1 |
| 7 | Product characteristics and pharmacokinetics of intranasal ipratropium bromide显示文摘 | CHESTER C W PHILIP F JAY G | 1995 | Journal of Allergy Clinical Immunology1995，95，： | 1 |
| 8 | Reactivity of heat treated coals in air at 500 ℃ 显示文摘 | ROBERT G J SATYENDRA P N PHILIP L W J | 1973 | Fuel1973，52，4： | 1 |
| 9 | 临床怀疑深静脉血栓形成病人的压迫超声诊断:前瞻性队列研究显示文摘目的:评价临床上怀疑为深静脉血栓形成但压迫超声显像所见正常病人不给予肝素治疗的安全性。设计:根据一种简化的程序来做压迫超声显像,超声显像的部位限于3处,即腹股沟部的股总静脉、腘静脉及胭静脉远端小腿静脉的分叉部位。初诊时超声显像为正常的病人1周后再重复检查1次。评价结果的标准:对于临床上怀疑为深静脉血栓形成的病人,凡是间隔1周两次超声显像均正常者则不予以肝素治疗,随访6个月,统计在这段时间内静脉血栓栓塞合并症的发生率。参加单位:四所大学附属医院的研究中心。结果:本研究共包括1702名病人,第一次检查发现400名血栓形成者,第二次检查又发现12名,因此用超声诊断方法在该1702名临床上怀疑为深静脉血栓形成的病人中确诊了412例,占24%。全组病人均获得随访,在两次 B 超检查之间,有1例发生了静脉血栓性栓塞的合并症,在6个月随访期间又有8例,所以累计发生率为0.7%(95%可信限为0.3%~1.2%),登门随访及补做检查的次数为平均每例0.8次。结论:对于临床上怀疑为深静脉血栓形成的病人,若连续两次压迫超声检查均为正常者,不给予肝素治疗是安全的。 | Alberto Cogo Anthonie W A Lensing Maria M W Koopman Franco Piovella Sergio Siragusa Philip S Wells Sabina Villalta Harry R Bller Alexander G G Turpie Paolo Prandoni 冷希圣 | 1998 | 英国医学杂志中文版1998，0，1： | 1 |
| 10 | Randomized double-blind placebo- controlled study of montelukast for treating perennial allergic rhinitis 显示文摘 | Pate1 P Philip G Yang W | 2005 | Ann Allergy Asthma Immuno12005，95，6： | 1 |
| 11 | Isolation and structure assignments of rostratins A-D, cytotoxic disulfides produeed by the marine-derived fungus Exserohilum rostratum显示文摘 | TAN R X PAUL R J PHILIP G W | 2004 | J Nat Prod2004，67，： | 1 |
| 12 | Alternative practices for sediment and nutrient loss control on livestock farms in northeast Iowa 显示文摘 | W G Philip O Edward S All | 2006 | Agriculture Ecosystems & Environment2006，117，23： | 1 |
| 13 | Reaction of ferrous and ferric ions with hydrogen peroxide 显示文摘 | Barb W G Baxendale J H Philip George | 1949 | Nature1949，163，4148： | 1 |
| 14 | Stearidonic acid as a supplemental source of ω-3 polyunsaturated fatty acids to enhance status for improved human health显示文摘 | Celia G W Susan A J Philip C C | 2013 | Nutrition2013，29，2： | 1 |
| 15 | A brief history of electronic nose显示文摘 | Julian W G Philip N B | | Sensors and Actuators B:Chemical0，18，3： | 1 |
| 16 | Real-time control of multi-product bulk-service semiconductor manufacturing processes 显示文摘 | FOWLER J W PHILIPS D T HOGG G L | 1992 | IEEE Transactions on Semiconductor Manufacturing1992，5，2： | 1 |
| 17 | Marine actinomycete diversity and natural product discovery显示文摘 | Paul R J Tracy J M Philip G W | 2005 | Antonie van Leeuwenhoek2005，87，： | 1 |
| 18 | The soil and water assessment tool:Historical,development,applications,and future research directions显示文摘 | Philip W G Manuel R R Colleen H G | 2007 | Trans ASAE2007，50，4： | 1 |
| 19 | Azamerone,a terpenoid phthalazinone from a marine-derived bacterium related to the genus Streptomyces (Actinomycetales)显示文摘 | Ji Y C Hak C K Philip G W | 2006 | Org Lett2006，8，12： | 1 |
| 20 | Randomized, doubleblind, placebo-controlled study of montelukast for treating perennial allergic rhinitis显示文摘 | PATEL P PHILIP G YANG W | 2005 | Ann Allergy Asthma Immunol2005，95，6： | 1 |
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