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| 1 | Nuclear factor-kappa B and glucocorticoid receptor alpha-mediated mechanisms in the regulation of systemic and pulmonary inflammation during sepsis and a- cute respiratory distress syndrome: evidence for inflammation-induced target tissue resistance to glucocorticoids 显示文摘 | Meduri GU Muthiah PM Pierluigi C | 2005 | Neuroimmunomedulation2005，12，7： | 1 |
| 2 | Thymosin alpha1: the regulator of regu-lators 显示文摘 | Pierluigi B D'Angelo C FallarinoF | 2010 | Ann N Y Acad Sci2010，1194，： | 1 |
| 3 | Trigeneration primary energy saving evaluation for energy planning and policy development显示文摘 | Gianfranco C Pierluigi M | 2007 | Energy Policy2007，35，12： | 1 |
| 4 | Thymosin alphal: the regulator of regulators 显示文摘 | Pierluigi B D'Angelo C Fallarino F | 2010 | Ann N Y Acad Sci2010，11，94： | 1 |
| 5 | Apolipoprotein E polymorphism influences orthotopic liver transplantation outcomes in patients with hepatitis C virus-induced liver cirrhosis显示文摘BACKGROUND Hepatitis C virus(HCV)infection is responsible for a chronic liver inflammation,which may cause end-stage liver disease and hepatocellular carcinoma.Apolipoprotein E(protein:ApoE,gene:APOE),a key player in cholesterol metabolism,is mainly synthesized in the liver and APOE polymorphisms may influence HCV-induced liver damage.AIM To determine whether APOE alleles affect outcomes in HCV-infected patients with liver cirrhosis following orthotopic liver transplantation(OLT).METHODS This was a cohort study in which 179 patients,both genders and aged 34-70 years,were included before or after(up to 10 years follow-up)OLT.Liver injury severity was assessed using different criteria,including METAVIR and models for endstage liver disease.APOE polymorphisms were analyzed by quantitative real-time polymerase chain reaction.RESULTS The APOE3 allele was the most common(67.3%).In inflammation severity of biopsies from 89 OLT explants and 2 patients in pre-transplant,the degree of severe inflammation(A3F4,0.0%)was significantly less frequent than in patients with minimal and moderate degree of inflammation(≤A2F4,16.2%)P=0.048,in patients carrying the APOE4 allele when compared to non-APOE4.In addition,a significant difference was also found(≤A2F4,64.4%vs A3F4,0.0%;P=0.043)and(A1F4,57.4%vs A3F4,0.0%;P=0.024)in APOE4 patients when compared to APOE3 carriers.The fibrosis degree of the liver graft in 8 of 91 patients and the lack of the E4 allele was associated with more moderate fibrosis(F2)(P=0.006).CONCLUSION Our results suggest that the E4 allele protects against progression of liver fibrosis and degree of inflammation in HCV-infected patients. | José Carlos Rodrigues Nascimento Lianna C Pereira Juliana Magalhães C Rêgo Ronaldo P Dias Paulo Goberlânio B Silva Silvio Alencar C Sobrinho Gustavo R Coelho Ivelise Regina C Brasil Edmilson F Oliveira-Filho James S Owen Pierluigi Toniutto Reinaldo B Oriá | 2021 | World Journal of Gastroenterology2021，27，11： | 1 |
| 6 | GABA receptor antagonists and insecticides:common structural features of 4-alkyl-1-phenyIpyrazoles and 4-alkyl-1-phenyltrioxabicyclooctanes显示文摘 | Robert E S Pierluigi C Kathleen A D | 2004 | Casida Bioorganic & Medicinal Chemistry2004，12，： | 1 |
| 7 | Thymosin alpha1:the regulator of regulators显示文摘 | Pierluigi B D Angelo C Fallarino F | 2010 | Ann N Y Acad Sci2010，1194，： | 1 |
| 8 | Thymosin alphal : the regulator of regulators? 显示文摘 | Pierluigi B D' Angelo C Fallarino F | 2010 | Ann N Y Acad Sci2010，1194，： | 1 |
| 9 | Thymosin alphal: the regulator of regulators 显示文摘 | Pierluigi B D'Angelo C Fallarino F | 2010 | Ann N Y Acad Sci2010，1194，： | 1 |
| 10 | An energy optimi- zation strategy for power-split drivetrain plug-in hybrid electric vehicles 显示文摘 | Yiming H Mashrur C Pierluigi P | 2012 | Transportation Research Part C: Emerging Technologies2012，22，： | 1 |
| 11 | A double-blind,randomized parallel-group,efficacy and safety study of intramuscular S-adenosyl-L-methionine 1,4-butanedisulphonate (SAMe) versus imipramine in patients with major depressive disorder显示文摘 | PAOLO P PIERLUIGI S ROBERTO D C | 2002 | International J of Neuropsychopharmacology2002，5，： | 1 |
| 12 | Matrix modeling of small-scale ' trigeneration systems and application to operational optimi-zation 显示文摘 | Gianfranco C Pierluigi M | 2009 | Energy2009，34，3： | 1 |
| 13 | An improved method for the detection of Down's syndrome aneuploidy in uncultured aminocytes 显示文摘 | Pierluigi M Perfumo C Cavani S | 1996 | Clin Genet1996，49，： | 1 |
| 14 | Thymosin alphal:the regulator of regulators显示文摘 | Pierluigi B D'Angelo C Fallarino F | 2010 | Ann Ny Acad Sci2010，1194，1： | 1 |
| 15 | Liquid chromatography- tandem mass spectrometric ion - switching determination of ehlorantraniliprole and flubendiamide in fruits and vegetables 显示文摘 | Pierluigi C Giorgia S Alberto A | 2008 | Journal of Agricultural & Food Chemistry2008，56，17： | 1 |
| 16 | Distributed muhi-genera- tion: A comprehensive view 显示文摘 | GIANFRANCO C PIERLUIGI M | 2009 | Renewable and Sustainable Energy Reviews2009，13，3： | 1 |
| 17 | An elastic demand sched- ule-based multimodal assignment model for the simu- lation of high speed rail (HSR) systems 显示文摘 | ENNIO C PIERLUIGI C | 2012 | EURO Journal on Transportation and Logistics2012，，2： | 1 |
| 18 | Caspase-dependent alterations of Ca2+ signaling in the induction of apoptosis by hepatitis B virus X protein显示文摘 | MOUNIA C DAVIDE F PIERLUIGI N e t al | 2003 | J Biol Chem2003，278，31： | 1 |
| 19 | Phenylpyrazole Insecticide Photochemistry, Metabolism, and GABAergic Action: Ethiprole Compared with Fipronil 显示文摘 | Pierluigi C Robert E S John E C | 2003 | J Agric Food Chem2003，51，24： | 1 |
| 20 | Matrix modeling of small- scale trigeneration systems and application to operation- al optimization显示文摘 | Gianfraneo C Pierluigi M | 2009 | Energy2009，34，3： | 1 |
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