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    题名 作者 年代 出处 被引量
1体内腺相关病毒-常间回文重复序列丛集及其相关蛋白9介导的基因编辑可改善家族性高胆固醇血症的动脉粥样硬化显示文摘低密度脂蛋白受体(low-density lipoprotein receptor,Ldlr)基因突变是家族性高胆固醇血症的主要原因之一,可导致动脉粥样硬化,并具有很高的终生心血管病风险。常间回文重复序列丛集(clustered regularly interspaced short palindromic repeats,CRISPR)/CRISPR相关蛋白9(CRISPR-related protein 9,Cas9)系统是基因编辑纠正基因突变从而改善疾病的有效工具。该研究的目的是通过腺相关病毒(adeno-associated virus,AAV)携带的CRISPR/Cas9系统进行体内体细胞基因编辑,以确定其能否在小鼠模型中治疗由Ldlr突变体引起的家族性高胆固醇血症。刘青(译) 叶鹏(审校) Zhao H Li Y He L Pu W Yu W Li Y Wu YT Xu C Wei Y Ding Q Song BL Huang H Zhou B 2020中华高血压杂志2020,28,3:22
2Satellite sensor image classification using cascaded architecture of neural fuzzy network显示文摘Lin C T Lee Y C Pu P H 2000IEEE Transactions on Geoscience and Remote Sensing2000,38,2:2
3Growth and properties of REBiO3 new buffer materials for coated conductors 显示文摘Li G Pu M H Sun R P 2008Physica C2008,468,:1
4HIV-1 Tat protein upregulates inflammatory mediators and induces monocyte invasion into the brain显示文摘Pu H Tian J Flora G 2003Mol Cell Neurosci2003,24,1:1
5Coherent population trapping and dynamical instability in coupled atom-molecule condensates显示文摘Ling H Y Maenner P Pu H 2005Phys Rev2005,72,01:1
6A new disease in rabbits显示文摘Liu S J Xue H P Pu B Q 1984Anima Husb Vet Med1984,16,:1
7Diffusion of sucrose and yohinobine in calcium alginate gel beads with or without entrapped plant cells显示文摘Pu H T Yang R Y K 1988Biotech Bioeng1988,32,1:1
8Evidence of nanocrystalline semiconducting graphene monoxide during thermal reduction of graphene oxide in vacuum显示文摘Mattson E C Pu H Cui S 2011ACS nano2011,5,:1
9The efferent segment in continent cutaneous urinary diversion:a comprehensive review of the literature显示文摘Ardelt PU Woodhouse CR Riedmil er H 0,,:1
10Freeze-drying of human red blood cells: influence of carbohydrates and their concentrations显示文摘Yu Jianping Liu J H Pu L Q Cui Xiangdong Wang Changzheng Ouyang S L Gao Dayong 2004Cell Preservation Technology2004,2,4:1
11Amphiphilic graphene composites 显示文摘Qi X Pu KY Li H 2010Angew Chem Int Ed Engl2010,49,49:1
12Charge/discharge characteristics of sulfur composite cathode materials in reehargeable lithium batteries显示文摘He X M Pu W H Ren J G 2007Electrochim Acta2007,52,25:1
13Electrodeposition of Sn-Cu alloy anodes for lithium batteries显示文摘PU W H HE X M REN J G 2005Electrochimica Acta2005,50,20:1
14Self-trapping of a Fermi superfluid in a double-well potential in the Bose-Einstein-condensateunitarity crossover 显示文摘ADHIKARI S K LU H PU H 2009PhysRev A2009,80,:1
15Influence of sintering at- mosphere on dielectric properties and microstructure of CaCu3Ti4012 ceramics 显示文摘Wang B Pu Y P Wu H D 2013Ceramics International2013,39,:1
16Synthesis and properties of polyfor proton conducting membranes in fuel cells显示文摘Guan Y Pu H Wan D 2011Polymer Chemistry Articles2011,39,2:1
17Functional analyses of coronary artery disease associated variation on chromosome 9p21 in vascu- lar smooth muscle cells显示文摘Motterle A Pu X Wood H 2012Hum Mol Genet2012,21,18:1
18Reducing unnecessary right ventricular pacing with the managed ventricular pacing mode in patients with sinus node disease and AV block 显示文摘Gillis AM Pu'rerfellner H Israel CW 2006Pacing Clin Electrophysiol2006,29,:1
19Laparoscopic versus open pyeloplasty for ureteropelvic junction obstruction in children:a systematic review and meta-analysis显示文摘Mei H Pu J Yang C 2011J Endourol2011,25,5:1
20Motor neuron degeneration in mice that express a human Cu,Zn superoxide dismutase mutation显示文摘Gurney M E Pu H Chiu A Y 0,,5166:1
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