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| 1 | Ultrasensitive skin‐like wearable optical sensors based on glass micro/nanofibers显示文摘Electronic skin,a class of wearable electronic sensors that mimic the functionalities of human skin,has made remarkable success in applications including health monitoring,human-machine interaction and electronic-biological interfaces.While electronic skin continues to achieve higher sensitivity and faster response,its ultimate performance is fundamentally limited by the nature of low-frequency AC currents.Herein,highly sensitive skin-like wearable optical sensors are demonstrated by embedding glass micro/nanofibers(MNFs)in thin layers of polydimethylsiloxane(PDMS).Enabled by the transition from guided modes into radiation modes of the waveguiding MNFs upon external stimuli,the skin-like optical sensors show ultrahigh sensitivity(1870 k·Pa^-1),low detection limit(7 mPa)and fast response(10μs)for pressure sensing,significantly exceeding the performance metrics of state-of-the-art electronic skins.Electromagnetic interference(EMI)-free detection of high-frequency vibrations,wrist pulse and human voice are realized.Moreover,a five-sensor optical data glove and a 2×2-MNF tactile sensor are demonstrated.These initial results pave the way toward a new category of optical devices ranging from ultrasensitive wearable sensors to optical skins. | Lei Zhang Jing Pan Zhang Zhang Hao Wu Ni Yao Dawei Cai Yingxin Xu Jin Zhang Guofei Sun Liqiang Wang Weidong Geng Wenguang Jin Wei Fang Dawei Di Limin Tong | 2020 | Opto-Electronic Advances2020，3，3： | 12 |
| 2 | Systemic induction of H_(2)O_(2) in pea seedlings pretreated by wounding and exogenous jasmonic acid显示文摘Pea seedlings (Pisum sativum L.) were used as materials to test the timings and compartments of hydrogen peroxide (H2O2) triggered by wounding and exogenous jasmonic acid (JA). The results showed that H2O2 could be systemically induced by wounding and exogenous JA. H2O2 increased within 1 h and reached the peak 3―5 h after wounding in either the wounded leaves or the unwounded leaves adjacent to the wounded ones and the inferior leaves far from the wounded ones. After this, H2O2 decreased and recovered to the control level 12 h after wounding. The activities of antioxidant enzymes, however, were rapidly increased by wounding. Diphenylene iodonium (DPI), an inhibitor of NADPH oxidase, could significantly inhibit H2O2 burst that was mediated by wounding and exogenous JA. Assay of H2O2 subcellular location showed that H2O2 in response to wounding and exogenous JA was predominantly accumulated in plasma membrane, cell wall and apoplasmic space. Numerous JA (gold particles) was found via immu- nogold electron microscopy to be located in cell wall and phloem zones of mesophyll cell after wounding. | LIU Yan 1,2 , HUANG Weidong 1 , ZHAN Jicheng 1 & PAN Qiuhong 1 1. College of Food Science and Nutritional Engineering, China Agricultural University, Beijing 100083, China 2. College of Agronomy, Inner Mongolia Agricultural University, Huhhot 010019, China | 2005 | Science China(Life Sciences)2005，48，3： | 7 |
| 3 | Microstructure and strengthening mechanism of hot-extruded ultralight Mg-Li-Al-Sn alloys with high strength显示文摘Duplex-structured Mg-7Li-2Al-1.5Sn alloys with high strength were fabricated and their strengthening mechanism was investigated.The Mg-7Li-2Al-1.5Sn alloys were prepared by casting and extruded at the temperature of 533 K with an extrusion ratio of 25:1.The microstructure and mechanical properties of Mg-7Li-2Al-1.5Sn alloys were systematically investigated by OM,XRD,SEM,TEM,and tensile tests.The results show that Mg-7Li-2Al-1.5Sn alloys are mainly composed ofα-Mg,β-Li,LiMgAl_(2),Mg_(2)Sn and Li_(2)MgSn phases.The yield strength(YS),ultimate tensile strength(UTS)and elongation(EL)of the extruded alloy at room temperature reach 250 MPa,324 MPa and 11.9%,respectively.A lot of Sn-rich precipitates(Mg_(2)Sn and Li_(2)MgSn)are precipitated during extrusion with an average size of∼14 nm,which is beneficial to the grain refinement.Dynamic recrystallization occurs during hot deformation and the nanoprecipitates effectively refine the dynamic recrystallized(DRXed)grains.Besides,the residual dislocations existed in DRXed and un-DRXed grains result in the dislocation strengthening in the extruded alloy.Mg7Li-2Al-1.5Sn alloys possess excellent high-temperature mechanical properties with the YS,UTS and EL of 200 MPa,237 MPa and 26.7%at 423 K,respectively.Sn-rich precipitates with good thermal stability can effectively prevent grain growth,which is good for the improvement of the high-temperature performance of Mg-Li-Al-Sn alloy. | Gang Zhou Yan Yang Hanzhu Zhang Faping Hu Xueping Zhang Chen Wen Weidong Xie Bin Jiang Xiaodong Peng Fusheng Pan | 2022 | Journal of Materials Science & Technology2022，，8： | 7 |
| 4 | Construction of molecule-selective mixed matrix membranes with confined mass transfer structure显示文摘Extraordinary mass transfer phenomenon is usually found when the small molecules pass through a confined structure, whose effective size is commensurate with the mean free path of the molecules. Small changes in the confined mass transfer structure(including size, morphology and properties) will lead to significant fluctuations of the mass transfer coefficient. The mass transfer of the penetrant molecules in the dense membranes for pervaporation, gas separation and so on, is located in the scope of confined mass transfer. Incorporating nanofillers into polymer matrix to construct mixed matrix membranes(MMMs) is an effective approach to tune the confined mass transfer structure and enhance the performance of the widely used polymeric membranes. This review focuses on the construction and manipulation of the confined structure in the polymeric membranes via incorporating one-dimensional(1D), two-dimensional(2D) and three-dimensional(3D) fillers.The comparison of the MMMs for pervaporation is summarized, and the research prospective of the MMMs is provided. | Weidong Li Fusheng Pan Yimeng Song Meidi Wang Hongjian Wang Shalik Walker Hong Wu Zhongyi Jiang | 2017 | Chinese Journal of Chemical Engineering2017，25，11： | 3 |
| 5 | Effect of Mn content on the microstructure and mechanical properties of Mg–6Li–4Zn-xMn alloys显示文摘The as-cast Mg–6Li–4Zn-x Mn alloys were prepared and extruded at 280℃with an extrusion ratio of 25:1.The effects of Mn content on the microstructure and mechanical properties of Mg–6Li–4Zn-x Mn alloys were investigated in this study.The XRD results show that Mg–6Li–4Zn–x Mn alloys consisted ofα-Mg(hcp)+β-Li(bcc)duplex structured matrix,Mg Li_(2)Zn and Mn phases.The grains of the extruded Mg–6Li–4Zn–x Mn alloys were refined by dynamic recrystallization during the extrusion process.The EBSD results show that the extruded alloys had basal textures.The grain size of the extruded alloys decreased while the basal texture was strengthened with the increasing Mn addition.The TEM results show that a large amount of nanoscale Mn precipitates existed in the extruded Mg–6Li–4Zn–1.2 Mn alloy,which can effectively inhibit the dynamic recrystallized(DRXed)grains growth during the hot extrusion and is beneficial to the improvement of mechanical properties.Mg–6Li–4Zn–1.2 Mn alloy in this research possesses the best mechanical properties with the ultimate tensile strength and yield strength of 321 MPa,250 MPa,respectively. | Hongju Deng Yan Yang Minmin Li Xiaoming Xiong Guobing Wei Weidong Xie Bin Jiang Xiaodong Peng Fusheng Pan | 2021 | Progress in Natural Science:Materials International2021，31，4： | 3 |
| 6 | Porphyromonas gingivalis bacteremia increases the permeability of the blood-brain barrier via the Mfsd2a/Caveolin-1 mediated transcytosis pathway显示文摘Bacteremia induced by periodontal infection is an important factor for periodontitis to threaten general health. P. gingivalis DNA/virulence factors have been found in the brain tissues from patients with Alzheimer’s disease(AD). The blood-brain barrier(BBB) is essential for keeping toxic substances from entering brain tissues. However, the effect of P. gingivalis bacteremia on BBB permeability and its underlying mechanism remains unclear. In the present study, rats were injected by tail vein with P. gingivalis three times a week for eight weeks to induce bacteremia. An in vitro BBB model infected with P. gingivalis was also established. We found that the infiltration of Evans blue dye and Albumin protein deposition in the rat brain tissues were increased in the rat brain tissues with P. gingivalis bacteremia and P. gingivalis could pass through the in vitro BBB model. Caveolae were detected after P. gingivalis infection in BMECs both in vivo and in vitro. Caveolin-1(Cav-1) expression was enhanced after P. gingivalis infection.Downregulation of Cav-1 rescued P. gingivalis-enhanced BMECs permeability. We further found P. gingivalis-gingipain could be colocalized with Cav-1 and the strong hydrogen bonding between Cav-1 and arg-specific-gingipain(RgpA) were detected.Moreover, P. gingivalis significantly inhibited the major facilitator superfamily domain containing 2a(Mfsd2a) expression. Mfsd2a overexpression reversed P. gingivalis-increased BMECs permeability and Cav-1 expression. These results revealed that Mfsd2a/Cav-1 mediated transcytosis is a key pathway governing BBB BMECs permeability induced by P. gingivalis, which may contribute to P. gingivalis/virulence factors entrance and the subsequent neurological impairments. | Shuang Lei Jian Li Jingjun Yu Fulong Li Yaping Pan Xu Chen Chunliang Ma Weidong Zhao Xiaolin Tang | 2023 | International Journal of Oral Science2023，15，1： | 3 |
| 7 | Prostaglandin E2 modulates F-actin stress fiber in FSS-stimulated MC3T3-E1 cells in a PKA-dependent manner显示文摘骨头质量上的前列腺素 E2 (PGE2 ) 的效果在 vivo 是生长得很好的。以前的研究证明了 PGE2 增加区别,增长,并且在静态地有教养的造骨细胞通过 F 肌动朊压力纤维调整房间形态学。然而,造骨细胞上的 PGE2 的效果面对液体砍应力(FSS ) 它能更好揭开在 vivo 的 PGE2 的 anabolism 的效果,还得被检验。这里,我们假设了那 PGE2 通过蛋白质 kinase A (PKA ) 在刺激 FSS 的 MC3T3-E1 osteoblastic 房间调制 F 肌动朊压力纤维小径。而且,改变的这导致 PGE2 的 F 肌动朊与细胞的 mechanosensitivity 的恢复被联系。我们的数据证明有为 15 min 的 10 nM dmPGE2 的处理显著地以一种 PKA 依赖的方式在刺激 FSS 的房间压制了 F 肌动朊压力纤维紧张。另外, dmPGE2 处理提高了房间的钙山峰大小和在第二 FSS 刺激回答房间的百分比,尽管这些效果被合作处理与 phalloidin 废除并且稀释。我们的结果证明 10 nM dmPGE2 能通过 PKA 小径部分加速 F 肌动朊压力纤维的重设过程到它的预先刺激的水平,并且因此支持了细胞的 mechanosensitivity 的恢复。我们发现 PGE2 由增加了出现在 vivo 的骨头形成的新奇细胞的机制提供,建议那 PGE2 能是为骨头的处理的一个潜在的目标形成相关的疾病。 | Xiaoyuan Gong Weidong Yang Liyun Wang Randall L. Duncan Jun Pan | 2014 | Acta Biochimica et Biophysica Sinica2014，46，1： | 3 |
| 8 | Helicobacter pylori antibody responses in association with eradication outcome and recurrence: a population-based intervention trial with 7.3-year follow-up in China显示文摘Objective:To identify serum biomarkers that may predict the short or long term outcomes of anti-Helicobacter pylori(H.pylori)treatment,a follow-up study was performed based on an intervention trial in Linqu County,China.Methods:A total of 529 subjects were selected randomly from 1,803 participants to evaluate total anti-H.pylori immunoglobulin G(Ig G)and 10 specific antibody levels before and after treatment at 1-,2-and 7.3-year.The outcomes of anti-H.pylori treatment were also parallelly assessed by 13C-urea breath test at 45-d after treatment and 7.3-year at the end of follow-up.Results:We found the medians of anti-H.pylori Ig G titers were consistently below cut-off value through 7.3years in eradicated group,however,the medians declined in recurrence group to 1.2 at 1-year after treatment and slightly increased to 2.0 at 7.3-year.While the medians were significantly higher(>3.0 at 2-and 7.3-year)among subjects who failed the eradication or received placebo.For specific antibody responses,baseline seropositivities of Fli D and Hpa A were reversely associated with eradication failure[for Fli D,odds ratio(OR)=0.44,95%confidence interval(95%CI):0.27–0.73;for Hpa A,OR=0.32,95%CI:0.17–0.60].The subjects with multiple positive specific antibodies at baseline were more likely to be successfully eradicated in a linear fashion(Ptrend=0.006).Conclusions:Our study suggested that total anti-H.pylori Ig G level may serve as a potential monitor of longterm impact on anti-H.pylori treatment,and priority for H.pylori treatment may be endowed to the subjects with multiple seropositive antibodies at baseline,especially for Fli D and Hap A. | Tianyi Wang Yang Zhang Huijuan Su Zhexuan Li Lian Zhang Junling Ma Weidong Liu Tong Zhou Weicheng You Kaifeng Pan | 2017 | Chinese Journal of Cancer Research2017，29，2： | 3 |
| 9 | Non-parallel double-crack propagation in rock-like materials under uniaxial compression显示文摘Coalescence among fractures would have influence on the stability of rock masses. Deep understanding of mechanical behavior of fractured rock masses is an important mean to identify failure mechanism of geological disaster. In this study, crack propagation processing was studied through loading pre-fractured specimens of concrete block, termed as rock-like material, in uniaxial compression tests. New non-parallel double-crack geometry was introduced to observe crack coalescence. The flaw combinations are different from the normally used flaw configurations. In addition, ultrasonic detection tests were performed on the test blocks. The stress and strain data of these tests and characteristic parameters of sound wave were recorded. The stress-strain curves of each test block under the uniaxial compression test were drawn, relations among deformation characteristics and crack angle of the crack specimens, and their overall strength were analyzed. It is found that strength of the specimen decreases as crack inclination increases under two crack inclinations. The highest uniaxial compressive strength is found in the specimen with the cracks at the same angle in different directions. Based on description of the crack initiation location, crack surface and the ultimate failure patterns, failure modes of eight subtype for test blocks are divided into three categories. It is expected that the study results could be beneficial for engineering application of jointed rock masses. | Weidong Pan Xin Wang Qiming Liu Yongkang Yuan Baodong Zuo | 2019 | International Journal of Coal Science & Technology2019，6，3： | 2 |
| 10 | Syntheses and Anti-cancer Activities of Derivatives of Tetrandrine and Fangchinoline显示文摘 | LIU Yazhou HUANG Lan SUN Qianyun ZHANG Maosheng LI Tianlei LIANG Guangyi PAN Weidong | 2014 | Chemical Research in Chinese Universities2014，30，6： | 2 |
| 11 | Numerical and experimental investigation of tip leakage vortex cavitation patterns and mechanisms in an axial flow pump显示文摘 | ZHANG Desheng SHI Weidong PAN Dazhi | 2015 | ASME Journal of Fluids Engineering2015，137，12： | 1 |
| 12 | Study on tip leakage vortex in an axial flow pump based on modified shear stress transport k-a turbulence model显示文摘 | ZHANG Desheng PAN Dazhi SHI Weidong | 2013 | Thermal Science2013，17，5： | 1 |
| 13 | Power-scalable sub-100-fs Tm laser at 2.08μm显示文摘We report on a power-scalable sub-100-fs laser in the 2-μm spectral range using a Tm;-doped‘mixed’(Lu,Sc);O;sesquioxide ceramic as an active medium.Pulses as short as 58 fs at 2076 nm with an average output power of 114 mW at a pulse repetition rate of approximately 82.9 MHz are generated by employing single-walled carbon nanotubes as a saturable absorber.A higher average power of 350 m W at 2075 nm is obtained at the expense of the pulse duration(65 fs).A maximum average power of 486 mW is achieved for a pulse duration of 98 fs and an optical conversion efficiency of 22.3%,representing the highest value ever reported from sub-100-fs mode-locked Tm lasers. | Li Wang Weidong Chen Yongguang Zhao Hanlin Yang Wei Jing Zhongben Pan Hui Huang Jiachen Liu Ji Eun Bae Fabian Rotermund Pavel Loiko Xavier Mateos Zhengping Wang Xinguang Xu Uwe Griebner Valentin Petrov | 2021 | High Power Laser Science and Engineering2021，9，4： | 1 |
| 14 | Automatic rec- ognition of woven fabric pattern baaed on image processing and BP neural network 显示文摘 | Ruru Pan Weidong Gao Jihong Liu Hongbo Wang | 2011 | Journal of the Textile Institute2011，102，1： | 1 |
| 15 | Automatic recognition of woven fabric based on pattern database 显示文摘 | PAN Ruru GAO Weidong LIU Jihong | 2010 | Fibers and Polymers2010，11，2： | 1 |
| 16 | Deep Neural Network with Strip Pooling for Image Classification of Yarn-Dyed Plaid Fabrics显示文摘Historically,yarn-dyed plaid fabrics(YDPFs)have enjoyed enduring popularity with many rich plaid patterns,but production data are still classified and searched only according to production parameters.The process does not satisfy the visual needs of sample order production,fabric design,and stock management.This study produced an image dataset for YDPFs,collected from 10,661 fabric samples.The authors believe that the dataset will have significant utility in further research into YDPFs.Convolutional neural networks,such as VGG,ResNet,and DenseNet,with different hyperparameter groups,seemed themost promising tools for the study.This paper reports on the authors’exhaustive evaluation of the YDPF dataset.With an overall accuracy of 88.78%,CNNs proved to be effective in YDPF image classification.This was true even for the low accuracy of Windowpane fabrics,which often mistakenly includes the Prince ofWales pattern.Image classification of traditional patterns is also improved by utilizing the strip pooling model to extract local detail features and horizontal and vertical directions.The strip pooling model characterizes the horizontal and vertical crisscross patterns of YDPFs with considerable success.The proposed method using the strip pooling model(SPM)improves the classification performance on the YDPF dataset by 2.64%for ResNet18,by 3.66%for VGG16,and by 3.54%for DenseNet121.The results reveal that the SPM significantly improves YDPF classification accuracy and reduces the error rate of Windowpane patterns as well. | Xiaoting Zhang Weidong Gao Ruru Pan | 2022 | Computer Modeling in Engineering & Sciences2022，，3： | 1 |
| 17 | Research and development of nickle-based OCTG used in severe sour oil and gas fields显示文摘With an alloy content as high as 80%or more,Ni-based OCTG is a strategic products related to the state energy security,mainly applied in the exploitation and development of sour gas fields with complicate geological formation,high temperature,high pressure and severe corrosive well conditions.Ni-based OCTG is regarded as the pipe product with most high technologies due to the complexity and great difficulty in manufacturing and rigorous requirements in quality control.In this paper,the technical features and quality requirements of Ni-based OCTG are summarized,and the quality and properties of the Ni-based OCTG products of Baosteel are introduced in detail.With the help of SEM,XPS and TEM,the corrosion mechanism of Nickle-based OCTG in the environments containing H2S,CO2,Cl- and elementary suifur are also analyzed. | ZHANG Zhonghua,ZHANG Chunxia,PAN Dagang and SHAO Weidong Baoshan Iron & Steel Co.,Ltd.,Shanghai 201900,China | 2010 | Baosteel Technical Research2010，4，S1： | 1 |
| 18 | Shen-Zhi-Ling oral solution improves learning and memory ability in Alzheimer’s disease mouse model显示文摘OBJECTIVE: To investigate the effector mechanisms and effector targets of Shen-Zhi-Ling (SZL) oral solution in the treatment of Alzheimer's disease (AD). METHODS: In this study, we carried out gavage with SZL oral solution in an APP/PS-1 heterozygous double transgenic AD mouse model for 12 continuous weeks. Haematoxylin and eosin staining, Nissl staining and Annexin V/Propidium Iodide staining were used to detect the brain histopathology in AD mouse model. Immunofluorescence staining was used to detect the expression levels of autophagy's proteins. Morris water maze test was used to detect the learning and memory ability in AD mouse model. RESULTS: Pathological results showed that neuronal loss in the hippocampus of mice in the SZL intervention group was significantly alleviated and the number of apoptotic neurons was significantly decreased compared with the control group (physiological saline and non-intervention groups). Immunofluorescence staining results showed that the expression of autophagy activators, Beclin-1 and LC3B, was significantly increased in the hippocampal neurons of mice of the SZL intervention group, while the expression of the apoptotic factor, caspase- 3, was significantly decreased. At the same time, hippocampal accumulation of Aβ42 protein was significantly decreased. In addition, results of the water maze experiment showed that the latency period in mice from the SZL intervention group was significantly reduced. CONCLUSION: In summary, we believe that the SZL oral solution significantly activates autophagy in hippocampal neurons, effectively reducing the accumulation of Aβ42 peptides, alleviating neuronal injury and apoptosis, and ultimately improving the cognitive function in a mouse model of AD. | Chi Huiying Liu Te Pan Weidong Chen Jiulin Wu Beiling Yu Zhihua Chen Chuan | 2019 | Journal of Traditional Chinese Medicine2019，39，5： | 1 |
| 19 | Comparative analysis of genetic diversity in sacred lotus (Nelumbo nucifera Gaertn.) using AFLP and SSR markers显示文摘 | Jihong Hu Lei Pan Honggao Liu Shuzhen Wang Zhihua Wu Weidong Ke Yi Ding | 2012 | Molecular Biology Reports2012，，4： | 1 |
| 20 | Automatic recognition of woven fabric patterns based on pattern database显示文摘 | Ruru Pan Weidong Gao Jihong Liu Hongbo Wang | 2010 | Fibers and Polymers2010，，2： | 1 |
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