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| 1 | High-density SNP-based genetic maps for the parents of an outcrossed and a selfed tetraploid garden rose cross, inferred from admixed progeny using the 68k rose SNP array显示文摘Dense genetic maps create a base for QTL analysis of important traits and future implementation of marker-assisted breeding.In tetraploid rose,the existing linkage maps include<300 markers to cover 28 linkage groups(4 homologous sets of 7 chromosomes).Here we used the 68k WagRhSNP Axiom single-nucleotide polymorphism(SNP)array for rose,in combination with SNP dosage calling at the tetraploid level,to genotype offspring from the garden rose cultivar‘Red New Dawn’.The offspring proved to be not from a single bi-parental cross.In rose breeding,crosses with unintended parents occur regularly.We developed a strategy to separate progeny into putative populations,even while one of the parents was unknown,using principle component analysis on pairwise genetic distances based on sets of selected SNP markers that were homozygous,and therefore uninformative for one parent.One of the inferred populations was consistent with self-fertilization of‘Red New Dawn’.Subsequently,linkage maps were generated for a bi-parental and a self-pollinated population with‘Red New Dawn’as the common maternal parent.The densest map,for the selfed parent,had 1929 SNP markers on 25 linkage groups,covering 1765.5 cM at an average marker distance of 0.9 cM.Synteny with the strawberry(Fragaria vesca)genome was extensive.Rose ICM1 corresponded to F.vesca pseudochromosome 7(Fv7),ICM4 to Fv4,ICM5 to Fv3,ICM6 to Fv2 and ICM7 to Fv5.Rose ICM2 corresponded to parts of F.vesca pseudochromosomes 1 and 6,whereas ICM3 is syntenic to the remainder of Fv6. | Mirjana Vukosavljev Paul Arens Roeland E Voorrips Wendy P C van't Westende G D Esselink Peter M Bourke Peter Cox W Eric van de Weg Richard G F Visser Chris Maliepaard Marinus J M Smulders | 2016 | Horticulture Research2016，3，1： | 6 |
| 2 | Artificial intelligence in gastroenterology: A state-of-the-art review显示文摘The development of artificial intelligence(AI)has increased dramatically in the last 20 years,with clinical applications progressively being explored for most of the medical specialties.The field of gastroenterology and hepatology,substantially reliant on vast amounts of imaging studies,is not an exception.The clinical applications of AI systems in this field include the identification of premalignant or malignant lesions(e.g.,identification of dysplasia or esophageal adenocarcinoma in Barrett’s esophagus,pancreatic malignancies),detection of lesions(e.g.,polyp identification and classification,small-bowel bleeding lesion on capsule endoscopy,pancreatic cystic lesions),development of objective scoring systems for risk stratification,predicting disease prognosis or treatment response[e.g.,determining survival in patients post-resection of hepatocellular carcinoma),determining which patients with inflammatory bowel disease(IBD)will benefit from biologic therapy],or evaluation of metrics such as bowel preparation score or quality of endoscopic examination.The objective of this comprehensive review is to analyze the available AI-related studies pertaining to the entirety of the gastrointestinal tract,including the upper,middle and lower tracts;IBD;the hepatobiliary system;and the pancreas,discussing the findings and clinical applications,as well as outlining the current limitations and future directions in this field. | Paul T Kröner Megan ML Engels Benjamin S Glicksberg Kipp W Johnson Obaie Mzaik Jeanin E van Hooft Michael B Wallace Hashem B El-Serag Chayakrit Krittanawong | 2021 | World Journal of Gastroenterology2021，27，40： | 6 |
| 3 | 轮胎工业用更安全的操作油显示文摘在欧洲 ,立法和公众压力正在使欧洲市场上的操作油性质发生变化。这引起欧洲橡胶行业对不使用有潜在致癌危险芳香油的新型轮胎和橡胶配方进行评述。本文对这一状况进行了研究 ,并探讨了美国市场上可能出现的动态 ,介绍了不同产品的需求量以及北美操作油和润滑基油制造不断变化的局面。 | Paul W H T Juergen E P 吴淑华 | 2002 | 轮胎工业2002，22，5： | 3 |
| 4 | ENETS Consensus Guidelines for the Management of Patients with Digestive Neuroendocrine Neoplasms: Functional Pancreatic Endocrine Tumor Syndromes显示文摘 | Jensen Robert T Cadiot Guillaume Brandi Maria L De Herder Wouter W Kaltsas Gregory Komminoth Paul Scoazec Jean-yves Salazar Ramon Sauvanet Alain Kianmanesh Reza | 2012 | Neuroendocrinology2012，，2： | 3 |
| 5 | A MyD88-dependent IFNyR-CCR2 signaling circuit is required for mobilization of monocytes and host defense against systemic bacterial challenge显示文摘 | Eric M Pietras Lloyd S Miller Carl T Johnson Ryan M O'Connell Paul W Dempsey Genhong Cheng | 2011 | Cell Research2011，21，7： | 2 |
| 6 | Cancer Genome Scanning in Plasma: Detection of Tumor-Associated Copy Number Aberrations, Single-Nucleotide Variants, and Tumoral Heterogeneity by Massively Parallel Sequencing显示文摘 | Chan K C Allen Jiang Peiyong Zheng Yama W L Liao Gary J W Sun Hao Wong John Siu Shing Shun N Chan Wing C Chan Stephen L Chan Anthony T C Lai Paul B S Chiu Rossa W K Lo Y M D | 2013 | Clinical Chemistry2013，，1： | 2 |
| 7 | Plant volatiles as a defense against insect herbivores 显示文摘 | PAUL W P JAMES H T | 1999 | Plant Physiology1999，121，： | 1 |
| 8 | Metabolism of chlorogenic acid by human plasma, liver,intestine and gut microflora显示文摘 | Geoff W Plumb Maria T Gareia-Conesa Paul A Kroon | 1999 | J Sci Food Agric1999，79，： | 1 |
| 9 | Control of gear shifts in dual dutch transmission powertrains 显示文摘 | PAUL D W NONG Z RICHARD T | 2011 | Mechanical Systems and Signal Processing2011，25，6： | 1 |
| 10 | Late paleocene to eocene paleocenography of the equatorial pacific ocean: stable isotopes recorded at ocean drilling program site 865, allison guyot显示文摘 | Zachos J C Thomas E Parrow M Paul C K Kelly D C Silva I P Sliter W V Lohmann K C | 1995 | Paleoceanography1995，10，： | 1 |
| 11 | MCM-48-like large meso- porous silicas with tailored pore structure: facile synthesis domain in a ternary triblock copolymer-butanol-bater sys- tem显示文摘 | Kim T W Kleitz F Paul B | 2005 | Journal of the American Chemical Society2005，127，20： | 1 |
| 12 | A new HPV-DNA test for cervical-cancer screening in developing regions: a cross-sectional study of clinical accuracy in rural China显示文摘 | You-lin Qiao John W Sellors Paul S Eder Yan-ping Bao Jeanette M Lim Fang-hui Zhao Bernhard Weigl Wen-hua Zhang Roger B Peck Ling Li Feng Chen Qing-jing Pan Attila T Lorincz | 2008 | Lancet Oncology2008，，10： | 1 |
| 13 | Extraction and char- actefization of humus with reference to clay-associated humus显示文摘 | Anderson D W Paul E A Arnaud R J S T | 1974 | Can J Soil Sci1974，54，3： | 1 |
| 14 | A computerized method of visual acuity testing显示文摘 | Roy W Beck Pamela S Moke Andrew H Turpin Frederick L Ferris John Paul SanGiovanni Chris A Johnson Eileen E Birch Danielle L Chandler Terry A Cox R.Clifford Blair Raymond T Kraker | 2003 | American Journal of Ophthalmology2003，，2： | 1 |
| 15 | Refined tippreparation by electrochemical etching and ultrahighvacuum treatment to obtain atomically sharp tips forscanning tunneling microscope and atomic forcemicroscope 显示文摘 | Hagedorn T Ouali M E Paul W | 2011 | Review of Scientific Instruments2011，82，11： | 1 |
| 16 | Response of tree legumes to rhizobial inoculation in relation to the population density of indigenous rhizobia显示文摘 | Dan T Harold H K Paul W S | 1993 | Soil Biology and Biochemistry1993，25，1： | 1 |
| 17 | Incorporating ecological sustain- ability into landscape planning显示文摘 | Jolande W T Paul O Adri B | 2007 | Landscape and Urban Plan- ning2007，79，： | 1 |
| 18 | Activity of deep abdominal muscles increases during submaximal flexion and extension efforts but antagonist co-contraction remains unchanged显示文摘 | McCook Donna T Vicenzino Bill Hodges Paul W | 2009 | JOURNAL OF ELECTROMYOGRAPHY AND KINESIOLOGY2009，，19： | 1 |
| 19 | Grainstructure evolution in a 6061 aluminum alloy during hottorsion显示文摘 | WILLIAM H V G WOJCIECH Z M PAUL T W | 2006 | Materials Science & Engineering A2006，419，12： | 1 |
| 20 | High grade activated carbon matting derived from the chemical activation and pyrolysis of natural fibre textitle waste显示文摘 | PAUL T W ANTON R R | 2004 | Journal of analytical and applied pyrolysis2004，71，： | 1 |
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