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| 1 | Meeting 24-h movement guidelines: Prevalence, correlates, and the relationships with overweight and obesity among Chinese children and adolescents显示文摘Background:Meeting 24-h movement guidelines by children and adolescents has been associated with improved indicators of health,although it has been under-studied in China.Hence,this study aimed to investigate the prevalence of meeting the 24-h movement guidelines,its correlates,and its relationships with body mass index in children and adolescents in China.Methods:Cross-sectional data from the 2017 Youth Study in China of 114,072 children and adolescents(mean age=13.75 years,49.18%boys)were used.Meeting 24-h movement guidelines(60 min of daily moderate-to-vigorous physical activity,2 h of daily leisure screen time,911 h and 810 h nightly sleep duration for 613-year-olds and 1417-year-olds,respectively)and height and weight of all participants were assessed.The prevalence of meeting the 24-h movement guidelines and World Health Organization weight status categories were determined.Generalized linear models were used to determine the correlates of meeting the 24-h movement guidelines and the relationships of meeting the 24-h movement guidelines with overweight(OW)and obesity(OB).Results:Only 5.12%of Chinese children and adolescents met the 24-h movement guidelines,and 22.44%were classified as OW/OB.Older children and adolescents were less likely to meet the 24-h movement guidelines.Parental education level and family income were positively related to meeting the 24-h movement guidelines.Children and adolescents meeting the 24-h movement guidelines showed lower odds ratios for OW/OB.Compared with participants meeting the 24-h movement guidelines,boys in 4th6th grades met none of the recommendations(OR=1.22,95%CI:1.061.40),met the screen time recommendation only(OR=1.13,95%CI:1.011.28),met the nightly sleep duration recommendation only(OR=1.14,95%CI:1.031.28),and had significantly higher odds ratios for OW/OB.Similar trends were observed for girls in 4th6th grades:meeting none of the guidelines(OR=1.35,95%CI:1.141.59),meeting sleep duration guidelines only(OR=1.23,95%CI:1.081.39),and meeting moderate-to-vigorous physical activity+nightly sleep duration guidelines(OR=1.24,95%CI:1.011.54).For girls in 7th9th grades,the following trend was observed:meeting none of the guidelines(OR=1.30,95%CI:1.011.67).Conclusion:Very few Chinese children and adolescents met the 24-h movement guidelines.Age(negatively correlated),parental education level,and family income(both positively correlated)were correlates of meeting the 24-h movement guidelines.Children and adolescents meeting the 24-h movement guidelines were more likely to have lower risks for OW/OB,especially in the youngest age group(Grades 46);and girls in the middle age group(Grades 79)were also more likely to have lower risks for OW/OB.Further research studies should explore additional correlates and determinants for meeting the 24-h movement guidelines.Also,future studies should use longitudinal or interventional designs to determine the relationships between meeting the 24-h movement guidelines and OW/OB and other health indicators,while taking sex and age differences into account. | Si-Tong Chen Yang Liu Mark S.Tremblay Jin-Tao Hong Yan Tang Zhen-Bo Cao Jie Zhuang Zheng Zhu Xueping Wu Lijuan Wang Yujun Cai Peijie Chen | 2021 | Journal of Sport and Health Science2021，10，3： | 12 |
| 2 | 小鼠骨骼肌挫伤后基因表达的时间进程(英文)显示文摘Background:Though the mechanisms of skeletal muscle regeneration are deeply understood,those involved in muscle contusion,one of the most common muscle injuries in sports medicine clinics,are not.The objective of this study is to explore the mechanisms involved in muscle regeneration after contusion injury.Methods:In this study,a total of 72 mice were used.Eight of them were randomly chosen for the control group,while the rest were subjected to muscle contusion.Subsequently,their gastrocnemius muscles were harvested at different time points.The changes in muscle morphology were assessed by hematoxylin and eosin(HE) stain.In addition,the gene expression was analyzed by real-time polymerase chain reaction.Results:The data showed that the expression of many genes,i.e.,specific markers of immune cells and satellite cells,regulatory factors for muscle regeneration,cytokines,and chemokines,increased in the early stages of recovery,especially in the first 3 days.Furthermore,there were strict rules in the expression of these genes.However,almost all the genes returned to normal at 14 days post-injury.Conclusion:The sequence of immune cells invaded after muscle contusion was neutrophils,M1 macrophages and M2 macrophages.Some CC(CCL2,CCL3,and CCL4) and CXC(CXCL10) chemokines may be involved in the chemotaxis of these immune cells.HGF may be the primary factor to activate the satellite cells after muscle contusion.Moreover,2 weeks are needed to recover when acute contusion happens as used in this study. | Weihua Xiao Yu Liu Beibei Luo Linlin Zhao Xiaoguang Liu Zhigang Zeng Peijie Chen | 2016 | Journal of Sport and Health Science2016，5，1： | 8 |
| 3 | Associations between parental support for physical activity and moderate-to-vigorous physical activity among Chinese school children: A cross-sectional study显示文摘Purpose: The objective of this study was to examine the associations between parental support for physical activity(PA) and levels of moderate-to-vigorous physical activity(MVPA) among Chinese school children.Methods: Study participants were 81,857 school-aged children(aged 9–17 years; mean age = 13 years; 49.0% boys) and their parents or guardians who took part in the 2016 Physical Activity and Fitness in China—The Youth Study project. The independent variables included various forms of parental support for PA ascertained through a survey completed by parents or guardians. The dependent variable was the children's average MVPA in minutes per day by self-report. Structure equation modeling was used to examine the associations between parental support for PA and children's MVPA minutes.Results: The overall mean for MVPA participation time for the child participants was 48.82 ± 28.71 min/day. Significant associations between various forms of parental support and MVPA among children were found. Parental encouragement, accompanying, financial support, involvement,and role modeling for PA were positively associated with a high level of student MVPA participation. Parental PA knowledge-sharing was not associated with MVPA. The patterns of the associations were similar across sex, residence locale(i.e., urban and rural), and school grades(primary,junior middle, and junior high schools).Conclusion: Findings from this study suggest that, among Chinese school children, parental support for PA is important in promoting and facilitating children's participation in MVPA. | Yang Liu Yajun Zhang Sitong Chen Jialin Zhang Zongchen Guo Peijie Chen | 2017 | Journal of Sport and Health Science2017，6，4： | 7 |
| 4 | The biological effect of recombinant humanized collagen on damaged skin induced by UV-photoaging:An in vivo study显示文摘The application of medical devices to repair skin damage is clinically accepted and natural polymer enjoys an important role in this field,such as collagen or hyaluronic acid,etc.However,the biosafety and efficacy of these implants are still challenged.In this study,a skin damage animal model was prepared by UV-photoaging and recombinant humanized type Ⅲ collagen(rhCol Ⅲ)was applied as a bioactive material to implant in vivo to study its biological effect,comparing with saline and uncrosslinked hyaluronic acid(HA).Animal skin conditions were non-invasively and dynamically monitored during the 8 weeks experiment.Histological observation,specific gene expression and other molecular biological methods were applied by the end of the animal experiment.The results indicated that rhCol Ⅲ could alleviate the skin photoaging caused by UV radiation,including reduce the thickening of epidermis and dermis,increase the secretion of Collagen Ⅰ(Col Ⅰ)and Collagen Ⅲ(Col Ⅲ)and remodel of extracellular matrix(ECM).Although the cell-material interaction and mechanism need more investigation,the effect of rhCol Ⅲ on damaged skin was discussed from influence on cells,reconstruction of ECM,and stimulus of small biological molecules based on current results.In conclusion,our findings provided rigorous biosafety information of rhCol Ⅲ and approved its potential in skin repair and regeneration.Although enormous efforts still need to be made to achieve successful translation from bench to clinic,the recombinant humanized collagen showed superiorities from both safety and efficacy aspects. | Jing Wang He Qiu Yang Xu Yongli Gao Peijie Tan Rui Zhao Zhanhong Liu Yajun Tang Xiangdong Zhu Chongyun Bao Hang Wang Hai Lin Xingdong Zhang | 2022 | Bioactive Materials2022，7，5： | 7 |
| 5 | Engineering Mesoporous Structure in Amorphous Carbon Boosts Potassium Storage with High Initial Coulombic Efficiency显示文摘Amorphous carbon shows great potential as an anode material for high-performance potassium-ion batteries;however,its abundant defects or micropores generally capture K ions,thus resulting in high irreversible capacity with low initial Coulombic efficiency(ICE)and limited practical application.Herein,pore engineering via a facile self-etching strategy is applied to achieve mesoporous carbon(meso-C)nanowires with interconnected framework.Abundant and evenly distributed mesopores could provide short K^+ pathways for its rapid diffusion.Compared to microporous carbon with highly disordered structure,the meso-C with Zn-catalyzed short-range ordered structure enables more K^+to reversibly intercalate into the graphitic layers.Consequently,the mesoC shows an increased capacity by ~100 mAh g^-1 at 0.1 A g^-1,and the capacity retention is 70.7% after 1000 cycles at 1 A g^-1.Multiple in/ex situ characterizations reveal the reversible structural changes during the charging/discharging process.Particularly,benefiting from the mesoporous structure with reduced specific surface area by 31.5 times and less defects,the meso-C generates less irreversible capacity with high ICE up to 76.7%,one of the best reported values so far.This work provides a new perspective that mesopores engineering can effectively accelerate K^+ diffusion and enhance K^+ adsorption/intercalation storage. | Ruiting Guo Xiong Liu Bo Wen Fang Liu Jiashen Meng Peijie Wu Jinsong Wu Qi Li Liqiang Mai | 2020 | Nano-Micro Letters2020，12，11： | 5 |
| 6 | A novel thermophilic endoglucanase from a mesophilic fungus Fusarium oxysporum显示文摘A novel thermophilic endoglucanase (EGt) was extracted from a mesophilic fungus (Fusarium oxysporum L19). We invoked conventional kinetic enzyme reactions using the sodium salt of carboxymethyl cellulose (CMC-Na) as substrate. EGt displayed optimal activity at 75℃ when kept running 30 min in the temperature range of 30―85℃. Thermal stability curve measured at 70℃ suggested that its half-life time is 15.1 min. The activity was enhanced in the presence of Co2+ or Mg2+ but inhibited by Pb2+ and Fe3+. Moreover, N-bromosuccinimide (NBS) modification resulted in a complete loss of EGt activity, suggesting that tryptophan residues may be involved in the enzyme active site. Amino acid composition analysis demonstrated that EGt contains more proline residues. EGt lacks activity towards p-nitro- phenyl cellobiose (pNPC). The N-terminal amino acid se- quence of EGt is SYRVPAANGFPNPDASQEKQ, and the gene of EGt was sequenced and analyzed. Extensive se- quence alignments failed to show any homology between EGt and any known endoglucanases. This is the first report addressing the thermal adaptation of a cellulolytic enzyme from the mesophilic fungus F. oxysporum. Maybe the ex- pression of multiple isoenzyme in an organism helps it adapt to complex living environments. | LIU Shuyan DUAN Xinyuan LU Xuemei GAO Peiji | 2006 | Chinese Science Bulletin2006，51，2： | 5 |
| 7 | A novel approach for estimating growth phases and parameters of bacterial population in batch culture显示文摘Using mathematical analysis, a new method has been developed for studying the growth kinetics of bacterial populations in batch culture. First, sampling data were smoothed with the spline interpolation method. Second, the instantaneous rates were derived by numerical differential tech-niques and finally, the derived data were fitted with the Gaussian function to obtain growth parameters. We named this the Spline-Numerical-Gaussian or SNG method. This method yielded more accurate estimates of the growth rates of bacterial populations and new parameters. It was possible to divide the growth curve into four different but continuous phases based on changes in the instantaneous rates. The four phases are the accelerating growth phase, the constant growth phase, the decelerat-ing growth phase and the declining phase. Total DNA content was measured by flow cytometry and varied depending on the growth phase. The SNG system provides a very powerful tool for describing the kinetics of bacterial population growth. The SNG method avoids the unrealistic assumptions generally used in the traditional growth equations. | ZHANG Huaiqiang LIU Yuqing LIU Bo GAO Peiji | 2006 | Science China(Life Sciences)2006，49，2： | 4 |
| 8 | Accurate assessment of antibiotic susceptibility and screening resistant strains of a bacterial population by linear gradient plate显示文摘The dynamics of a bacterial population exposed to theminimum inhibitory concentration (MIC) of an antibiotic is an important issue in pharmacological research.Therefore,a novel antibiotic susceptibility test is urgently needed that can both precisely determine the MIC and accurately select antibiotic-resistant strains from clinical bacterial populations.For this purpose,we developed a method based on Fick's laws of diffusion using agar plates containing a linear gradient of antibiotic.The gradient plate contained two layers.The bottom layer consisted of 15 mL agar containing the appropriate concentration of enrofloxacin and allowed to harden in the form of a wedge with the plate slanted such that the entire bottom was just covered.The upper layer consisted of 15 mL plain nutrient agar added with the plate held in the horizontal position.After allowing vertical diffusion of the drug from the bottom agar layer for 12 h,the enrofloxacin concentration was diluted in proportion to the ratio of the agar layer thicknesses.The uniform linear concentration gradient was verified by measuring the enrofloxacin concentration on the agar surface.When heavy bacterial suspensions were spread on the agar surface and incubated for more than 12 h,only resistant cells were able to form colonies beyond the boundary of confluent growth of susceptible cells.In this way,the true MIC of enrofloxacin was determined.The MICs obtained using this linear gradient plate were consistent with those obtained using conventional antibiotic susceptibility tests.Discrete colonies were then spread onto a gradient plate with higher antibiotic concentrations;the boundary line increased significantly,and gene mutations conferring resistance were identified.This new method enables the rapid identification of resistant strains in the bacterial population.Use of the linear gradient plate can easily identify the precise MIC and reveal the dynamic differentiation of bacteria near the MIC.This method allows the study of genetic and physiological characteristics of individual strains,and may be useful for early warning of antibiotic resistance that may occur after use of certain antimicrobial agents,and guide clinical treatment. | LIU YuQing LI JingRan DU JiaFa HU Ming BAI Hua QI Jing GAO Chao WEI TianTian SU Hong JIN JianLing GAO PeiJi | 2011 | Science China(Life Sciences)2011，54，10： | 4 |
| 9 | Characteristics and Driving Forces of Spatial Expansion of Oasis Cities and Towns in Hexi Corridor, Gansu Province, China显示文摘This paper presents an integrated study of urban spatial expansion in the Hexi Corridor, Gansu Province, China based on TM, ETM remote sensing data in 1987, 1990, 1995, 2000, 2006 and 2011. The study explores the characteristics of urban spatial expansion and dynamic mechanism by using expansion speed index, expansion intensity index, compact index, fractal dimension, and extended flexibility index. We built the index system of influencing factors of urban spatial expansion by using the grey incidence model. The results showed that urban spatial expansion rate in the Hexi Corridor has been on the upward trend since 1987. Expansion intensity showed an obvious upward trend, however, the upward trend varied in different urban areas. In addition, the urban structure was loose relatively, but the urban compactness was more obvious. The urban spatial form tended to be simple, and the urban land use tended to become more intensive. Urban spatial expansion experienced several stages: padding internally, external expansion and padding internally. The main driving factors of urban spatial expansion are not the urban water resources and the oasis scale, but one or several factors such as economy, traffic, population, resource and national policy. | LIU Hailong SHI Peiji TONG Huali ZHU Guofeng LIU Haimeng ZHANG Xuebin WEI Wei WANG Xinmin | 2015 | Chinese Geographical Science2015，25，2： | 3 |
| 10 | Tuning charge density of chimeric antigen receptor optimizes tonic signaling and CAR-T cell fitness显示文摘Tonic signaling of chimeric antigen receptor(CAR),i.e.,the spontaneous CAR activation in the absence of tumor antigen stimulation,is considered to be a pivotal event controlling CAR-T efficacy.However,the molecular mechanism underlying the spontaneous CAR signals remains elusive.Here,we unveil that positively charged patches(PCPs)on the surface of the CAR antigenbinding domain mediate CAR clustering and result in CAR tonic signaling.For CARs with high tonic signaling(e.g.,GD2.CAR and CSPG4.CAR),reducing PCPs on CARs or boosting ionic strength in the culture medium during ex vivo CAR-T cell expansion minimizes spontaneous CAR activation and alleviates CAR-T cell exhaustion.In contrast,introducing PCPs into the CAR with weak tonic signaling,such as CD19.CAR,results in improved in vivo persistence and superior antitumor function.These results demonstrate that CAR tonic signaling is induced and maintained by PCP-mediated CAR clustering.Notably,the mutations we generated to alter the PCPs maintain the antigen-binding affinity and specificity of the CAR.Therefore,our findings suggest that the rational tuning of PCPs to optimize tonic signaling and in vivo fitness of CAR-T cells is a promising design strategy for the nextgeneration CAR. | Jian Chen Shizhen Qiu Wentao Li Kun Wang Yu Zhang Han Yang Baichuan Liu Guangfei Li Li Li Min Chen Junjie Lan Jiahua Niu Peijie He Lei Cheng Gaofeng Fan Xin Liu Xianmin Song Chenqi Xu Haitao Wu Haopeng Wang | 2023 | Cell Research2023，33，5： | 2 |
| 11 | Texture synthesis via the matching compatibility between patches显示文摘A new patch-based texture synthesis method is presented in this paper. By the method, a set of patches that can be matched with a sampled patch for growing textures effectively, called the matching compat- ibility between patches, is generated first for each patch, and the set is further optimized by culling the patches that may cause synthesis confficts. In this way, similarity measurement calculation for selecting suitable patches in texture synthesis can be greatly saved, and synthesis confficts between neighbouring patches are substantially reduced. Furthermore, retrace computation is integrated in the synthesis process to improve the texture quality. As a result, the new method can produce high quality textures as texture optimization, the best method to date for producing good textures, and run in a time complexity linear to the size of the output texture. Experimental results show that the new method can interactively generate a large texture in 1024 × 1024 pixels, which is very difficult to achieve by existing methods. | WANG WenCheng LIU FeiTong HUANG PeiJie WU EnHua | 2009 | Science in China(Series F)2009，52，3： | 2 |
| 12 | The characteristics of oasis urban expansion and drive mechanism analysis:a case study on Ganzhou District in Hexi Corridor,China显示文摘Ganzhou District is an oasis city in the Zhangye Municipality of Gansu Province,China.Based on multi-temporal TM and ETM satellite remote sensing data in 1985,1996,2000,and 2012,and by using corrected figures of land use status over the same periods,the spatial area of Ganzhou District since 1985 was extracted with statistical methods,and urban spatial expansion was measured by quantitative research methods.The characteristics of spatial expansion of Ganzhou District were analyzed by urban expansion rate,expansion intensity index,compactness,fractal dimension,and the city center shift method.The results showed that the built-up area of Ganzhou District increased by 3.46 times during 1985–2012.The expansion in 1985–1996 was slow,during 1996–2000 it was rapid,and during 2000–2012 it was at a high speed.This city mainly expanded to the northeast and northwest.Government decision making had a decisive influence on urban expansion.Initially the expansion was uniform,but later the local transportation,economy,resources,population,and national policies factors had an obvious influence on urban expansion. | HuaLi Tong PeiJi Shi GuoFeng Zhu April Pearson QianGuo Li YuanFeng Liu HaiLong Liu | 2015 | Research in Cold and Arid Regions2015，7，3： | 2 |
| 13 | BiVO_(4)/TiO_(2) heterojunction with rich oxygen vacancies for enhanced electrocatalytic nitrogen reduction reaction显示文摘The large-scale production of ammonia mainly depends on the Haber-Bosch process,which will lead to the problems of high energy consumption and carbon dioxide emission.Electrochemical nitrogen fixation is considered to be an environmental friendly and sustainable process,but its efficiency largely depends on the activity and stability of the catalyst.Therefore,it is imperative to develop high-efficient electrocatalysts in the field of nitrogen reduction reaction(NRR).In this paper,we developed a BiVO_(4)/TiO_(2) nanotube(BiVO_(4)/TNT)heterojunction composite with rich oxygen vacancies as an electrocatalytic NRR catalyst.The heterojunction interface and oxygen vacancy of BiVO_(4)/TNT can be the active site of N2 dynamic activation and proton transition.The synergistic effect of TiO_(2) and BiVO_(4) shortens the proton transport path and reduces the over potential of chemical reaction.BiVO_(4)/TNT has high ammonia yield of 8.54µg·h^(−1)·cm^(−2) and high Faraday efficiency of 7.70%in−0.8 V vs.RHE in 0.1 M Na_(2)SO_(4) solution. | Yunliang Liu Peiji Deng Ruqiang Wu Ramadan A.Geioushy Yaxi Li Yixian Liu Fengling Zhou Haitao Li Chenghua Sun | 2021 | Frontiers of physics2021，16，5： | 1 |
| 14 | Electron theory study on mechanism of action of cobaltin Fe-Co-Cr based high-alloy steel显示文摘The valence electron structure of martensite in Fe-Co-Cr based high-alloy steel is calculated using the em-pirical electron theory of solids and molecules (EET). The results show that the incorporation of cobalt leads to a rise in nA from 0.3835 to 0.4684, which enhances the bonding forces between atoms in a-Fe matrix. Meanwhile, the incorporation of Co changes the valence electron structure of segregated structure units formed by C and other alloying elements, and increases nA for the segregated units containing C-Me sig-nificantly, resulting in changing the precipitation behavior of the secondary phases during tempering and strengtheningthe resistance to tempering. | LI Peijie, XIONG Yuhua, LIU Shuxun & ZENG DabenDepartment of Mechanical Engineering, Tsinghua University, Beijing100084, China | 2003 | Chinese Science Bulletin2003，48，2： | 1 |
| 15 | Function of a Low Molecular Weight Peptide from Trichoderma pseudokoningii S38 During Cellulose Biodegradation显示文摘 | Wei Wang Jie Liu Guanjun Chen Yingshu Zhang Peiji Gao | 2003 | Current Microbiology2003，，5： | 1 |
| 16 | Snow cover distribution, varia- bility, and response to climate change in Western China 显示文摘 | Qin Dahe Liu Shiyin Li Peiji | 2006 | Journal of Climate2006，19，9： | 1 |
| 17 | Snow cover distribution, variability and response to climate change in western China 显示文摘 | Qin Dahe Liu Shiyin Li Peiji | 2006 | Journal of Climate2006，19，： | 1 |
| 18 | Snow cover distribution, variabili- ty, and response to climate change in Western China显示文摘 | Qin Dahe Liu Shiyin Li Peiji | 2006 | Journal of Climate2006，19，9： | 1 |
| 19 | Snow cover distribution, varia- bility, and response to climate change in western China 显示文摘 | Qin Dahe Liu Shiyin Li Peiji | 2006 | Journal of Climate2006，19，： | 1 |
| 20 | Snow cover distribution, varia- bility, and response to climate change in western China 显示文摘 | Qin Dahe Liu Shiyin Li Peiji | 2006 | Journal of Climate2006，19，9： | 1 |
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