|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Activation of peracetic acid by metal-organic frameworks(ZIF-67)for efficient degradation of sulfachloropyridazine显示文摘Peracetic acid(PAA)-based system is becoming an emerging advanced oxidation process(AOP)for effective removal of organic contaminants from water.Various approaches have been tested to activate PAA,while no previous researches reported the application of metal-organic frameworks(MOFs)materials for PAA activation.In this study,zeolitic imidazole framework(ZIF)-67,a representative MOFs,was facile synthesized via direct-mixing method at room temperature,and tested for PAA activation and sulfachloropyridazine(SCP)degradation.The as-synthesized ZIF-67 exhibited excellent performance for PAA activation and SCP degradation with 100%of SCP degraded within 3 min,owing to the specific MOFs structure and abundant Co^(2+) sites.The pseudo-first-order kinetic model was applied to fit the kinetic data,with rate constant k_(1) of ZIF-67 activated PAA system 34.2 and 156.5 times higher than those of conventional Co_(3)O_(4)activated PAA and direct oxidation by PAA.Radical quenching experiments and electron paramagnetic resonance(EPR)analysis indicated that CH_(3)C(O)OO^(·)played a major role in this PAA activation system.Then,the Fukui index based on density functional theory(DFT)calculation was used to predict the possible reaction sites of SCP for electrophilic attack by CH_(3)C(O)OO^(·).In addition,the degradation pathway of SCP was proposed based on Fukui index values and intermediates detection,which mainly included the S-N bond cleavage and SO_(2)extrusion and followed by further oxidation,dechlorination,and hydroxylation.Therefore,ZIF-67 activated PAA is a novel strategy and holds strong potential for the removal of emerging organic contaminants(EOCs)from water. | Jun Duan Long Chen Haodong Ji Peishen Li Fan Li Wen Liu | 2022 | Chinese Chemical Letters2022，33，6： | 3 |
| 2 | The road map for green development of Western China显示文摘China has made some remarkable achievements in sustainable development,but the constant deterioration of the overall trend of the environment has not yet been effectively curbed.To achieve the goal of sustainable development,we must first ensure coordination and coherence of national development goals in different areas and adhere to green development road.To achieve the objectives related to green development,and to clarify the direction of green development in the next 20years,a road map is needed to guide and coordinate the process.This paper describes the concept of the green development road map,introduces a green development road map for the western region,and further elaborates it The road map clarifies the objectives and guiding principles of green development in the western region,points the areas that deserve more concern and institutional innovation,and builds a green development monitoring and evaluation(M&E)framework.Finally,the paper provides corresponding policy recommendations based on the established road map. | Robyn Kruk Derek Thompson Jiyuan Liu Xiangzheng Deng Peishen Wang | 2013 | Chinese Journal of Population,Resources and Environment2013，11，3： | 2 |
| 3 | Umbilical cord mesenchymal stem cell transplantation significantly improves neurological function in patients with sequelae of traumatic brain injury显示文摘 | Sen Wang Hongbin Cheng Guanghui Dai Xiaodong Wang Rongrong Hua Xuebin Liu Peishen Wang Guangming Chen Wu Yue Yihua An | 2013 | Brain Research2013，，： | 1 |
| 4 | MrgprF acts as a tumor suppressor in cutaneous melanoma by restraining PI3K/Akt signaling显示文摘The incidence of cutaneous melanoma(CM)has been increasing annually worldwide.In this study,we identify that MrgprF,a MAS related GPR family member,is decreased in cutaneous melanoma tissues and cell lines due to hypermethylation of its promoter region,and show that patients with CM expressing high levels of MrgprF exhibit an improved clinical outcome.We demonstrate that MrgprF forced expression inhibits tumor cell proliferation,migration,xenograft tumor growth,and metastasis.On the contrary,MrgprF knockdown promotes tumor cell proliferation and transformation of immortalized human keratinocyte-HaCaT cells,supporting the inhibitory role of MrgprF during tumor progression.Mechanistic studies reveal that MrgprF reduces the phosphoinositol‑3‑kinase(PI3K)complex formation between p101 and p110γsubunits,the critical step for phosphatidylinositol-(3,4)-P2(PIP2)conversion to phosphatidylinositol-(3,4,5)-P3(PIP3),and then reduces the activation of PI3K/Akt signaling.This effect can be reversed by Akt specific agonist SC79.In addition,AMG 706,a previously documented inhibitor for endothelial cell proliferation,is identified as a potential agonist for MrgprF,and can impede tumor growth both in vitro and in vivo.Taken together,our findings suggest that MrgprF,a novel tumor suppressor in cutaneous melanoma,may be useful as a therapeutic target in the future. | Qiushuo Shen Yanfei Han Kai Wu Yaomei He Xiulin Jiang Peishen Liu Cuifeng Xia Qiuxia Xiong Rui Liu Qianming Chen Yong Zhang Song Zhao Cuiping Yang Yongbin Chen | 2022 | Signal Transduction and Targeted Therapy2022，7，6： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员