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| 1 | Structure and properties of an ultra-high strength 7xxx aluminum alloy contained Sc and Zr显示文摘An ultra-high strength aluminum alloy was produced by casting and then extruded to rods.The effect of heat treatment on the microstructure and mechanical properties of the alloy was investigated.After single ageing(120℃,24 h),the tensile strength was 812.4 MPa and the elongation was 6.2%.After retrogression reaging(RRA),the tensile strength was 751.2 MPa and the elongation was 6.4%.The strengthening mechanism is considered as fine grain strengthening,substructure strengthening and dispersion strengthening by Al_3(Sc,Zr). | Xiaoyuan Dai Changqing Xia Xiaomin Peng Ke Ma | 2008 | Journal of University of Science and Technology Beijing2008，15，3： | 7 |
| 2 | Doxorubicin-loaded silicon nanoparticles impregnated into red blood cells featuring bright fluorescence, strong photostability, and lengthened blood residency显示文摘基于唯一的优点荧光灯硅 nanoparticles (SiNPs ) ,长发行量红血房间(RBC ) ,和反癌症药分子(即, doxorubicin (纪录影片)) ,我们开发了使妊娠进 RBC 的多功能的装载纪录影片的 SiNPs。重要地,产生的药交货系统(DDS ) 同时展出了结合的明亮的荧光柔韧的 photostability (即, 24% 损失荧光灯在 25 min 以后的紧张连续激光照耀) 并且显著地变长的血住处(即, t 1/2= 7.31 吗?? | Airui Jiang Bin Song Xiaoyuan Ji Fei Peng Houyu Wang Yuanyuan Su Yao He | 2018 | Nano Research2018，11，4： | 6 |
| 3 | Photostable and Biocompatible Fluorescent Silicon Nanoparticles for Imaging-Guided Co-Delivery of siRNA and Doxorubicin to Drug-Resistant Cancer Cells显示文摘The development of effective and safe vehicles to deliver small interfering RNA(siRNA) and chemotherapeutics remains a major challenge in RNA interference-based combination therapy with chemotherapeutics,which has emerged as a powerful platform to treat drug-resistant cancer cells.Herein,we describe the development of novel all-in-one fluorescent silicon nanoparticles(SiNPs)-based nanomedicine platform for imaging-guided co-delivery of siRNA and doxorubicin(DOX).This approach enhanced therapeutic efficacy in multidrug-resistant breast cancer cells(i.e.,MCF-7/ADR cells).Typically,the SiNP-based nanocarriers enhanced the stability of siRNA in a biological environment(i.e.,medium or RNase A) and imparted the responsive release behavior of siRNA,resulting in approximately 80% down-regulation of P-glycoprotein expression.Co-delivery of P-glycoprotein siRNA and DOX led to>35-fold decrease in the half maximal inhibitory concentration of DOX in comparison with free DOX,indicating the pronounced therapeutic efficiency of the resultant nanocomposites for drug-resistant breast cancer cells.The intracellular time-dependent release behaviors of siRNA and DOX were revealed through tracking the strong and stable fluorescence of SiNPs.These data provide valuable information for designing effective RNA interference-based co-delivery carriers. | Daoxia Guo Xiaoyuan Ji Fei Peng Yiling Zhong Binbin Chu Yuanyuan Su Yao He | 2019 | Nano-Micro Letters2019，11，2： | 5 |
| 4 | Metal-organic frameworks nanoswitch:Toward photo-controllable endo/lysosomal rupture and release for enhanced cancer RNA interference显示文摘Endo/lysosomal escape and gene release are two critical bottlenecks in gene delivery.Herein,a novel photo-controllable metal-organic frameworks(MOFs)nanoswitch is rationally designed for enhancing small interfering RNA(siRNA)delivery.One single laser triggers the“off-to-on”switching of MOFs nanocomplexes,inducing significant siRNA release accompanied by rapid MOFs dissociation into protonatable 2-methylimidazalo and osmotic rupturing Zn2+ions,which cooperatively contribute to remarkable endo/lysosomal rupture(∼90%).The simultaneous endo/lysosomal rupture and release enable a high spatio-temporal control on RNA interference for effective cancer therapy.Notably,the“off-to-on”switching also activates fluorescence recovery for real-time monitoring siRNA delivery.The nanoswitch could easily be extended to deliver other therapeutic agents(e.g.,DNA,protein,anticancer drug)for overcoming endo/lysosomal entrapment. | Gan Lin Yang Zhang Long Zhang Junqing Wang Ye Tian Wen Cai Shangui Tang Chengchao Chu JiaJing Zhou Peng Mi Xiaoyuan Chen Gang Liu | 2020 | Nano Research2020，13，1： | 5 |
| 5 | InAs/InP/ZnSe Core/Shell/Shell Quantum Dots as Near-Infrared Emitters:Bright,Narrow-Band,Non-Cadmium Containing,and Biocompatible显示文摘High quality InAs/InP/ZnSe core/shell/shell quantum dots have been grown by a one-pot approach.This engineered quantum dots with unique near-infrared(NIR)fluorescence,possessing outstanding optical properties,and the biocompatibility desired for in vivo applications.The resulting quantum dots have significantly lower intrinsic toxicity compared to NIR emissive dots containing elements such as cadmium,mercury,or lead.Also,these newly developed ultrasmall non-Cd containing and NIR-emitting quantum dots showed signifi cantly improved circulation half-life and minimal reticuloendothelial system(RES)uptake. | Renguo Xie Kai Chen Xiaoyuan Chen Xiaogang Peng | 2008 | Nano Research2008，1，6： | 4 |
| 6 | One-step ball milling-prepared nano Fe2O3 and nitrogendoped graphene with high oxygen reduction activity and its application in microbial fuel cells显示文摘Developing high activity,low-cost and long durability catalysts for oxygen reduction reaction is of great significance for the practical application of microbial fuel cells.The ftill exposure of active sites in catalysts can enhance catalytic activity dramatically.Here,novel Fe-N-doped graphene is successftilly synthesized via a one-step in situ ball milling method.Pristine graphite,ball milling graphene,N-doped graphene and Fe-N-doped graphene are applied in air cathodes,and enhanced performance is observed in microbial fuel cells with graphene-based catalysts.Particularly,Fe-Ndoped graphene achieves the highest oxygen reduction reaction activity,with a maximum power density of 1380±20 mW/m^2 in microbial fUel cells and a current density of 23.8 A/m^2 at-0.16 V in electrochemical tests,which are comparable to commercial Pt and 390%and 640%of those of pristine graphite.An investigation of the material characteristics reveals that the superior performance of Fe-Ndoped graphene results from the full exposure of Fe2O3 nanoparticles,pyrrolic N,pyridinic N and excellent Fe-N-G active sites on the graphene matrix.This work not only suggests the strategy of maximally exposing active sites to optimize the potential of catalysts but also provides promising catalysts for the use of microbial fuel cells in sustainable energy generation. | Xingguo Guo Qiuying Wang Ting Xu Kajia Wei Mengxi Yin Peng Liang Xia Huang Xiaoyuan Zhang | 2020 | Frontiers of Environmental Science & Engineering2020，14，2： | 3 |
| 7 | Highly soluble organic nitrate additives for practical lithium metal batteries显示文摘The stability of lithium metal anodes essentially dictates the lifespan of high-energy-density lithium metal batteries.Lithium nitrate(LiNO_(3))is widely recognized as an effective additive to stabilize lithium metal anodes by forming LiN_(x)O_(y)-containing solid electrolyte interphase(SEI).However,its poor solubility in electrolytes,especially ester electrolytes,hinders its applications in lithium metal batteries.Herein,an organic nitrate,isosorbide nitrate(ISDN),is proposed to replace LiNO_(3).ISDNhas a high solubility of 3.3M in ester electrolytes due to the introduction of organic segments in the molecule.The decomposition of ISDN generates LiN_(x)O_(y)-rich SEI,enabling uniform lithium deposition.The lifespan of lithium metal batteries with ISDN significantly increases from 80 to 155 cycles under demanding conditions.Furthermore,a lithium metal pouch cell of 439Whkg^(−1) delivers 50 cycles.This work opens a new avenue to develop additives by molecular modifications for practical lithium metal batteries. | Zhe Wang Li-Peng Hou Zheng Li Jia-Lin Liang Ming-Yue Zhou Chen-Zi Zhao Xiaoyuan Zeng Bo-Quan Li Aibing Chen Xue-Qiang Zhang Peng Dong Yingjie Zhang Jia-Qi Huang Qiang Zhang | 2023 | Carbon Energy2023，5，1： | 2 |
| 8 | Phylogenetic Analysis of the Dengue Virus Strains Causing the 2019 Dengue Fever Outbreak in Hainan,China显示文摘Dengue virus is an arthropod-borne pathogen that is transmitted to humans primarily by Aedes spp.mosquitos,causing the acute infectious disease,dengue fever(DF).Until 2019,no dengue outbreak had been reported in Hainan Province for over 20 years.However,in early September of 2019,an increasing number of infected cases appeared and the DF outbreak lasted for over one month in Haikou City,Hainan Province.In our study,we collected 97 plasma samples from DF patients at three hospitals,as well as 1585 mosquito larvae samples from puddles in different areas of Haikou.There were 49(50.5%)plasma samples found to be strongly positive and 9(9.3%)plasma samples were weakly positive against the NS1 antigen.We discovered DENV both in the patient's plasma samples and mosquito larvae samples,and isolated the virus from C6/36 cells inoculated with the acute phase serum of patients.Phylogenetic analysis revealed that the new strains were the most closely related to the epidemic strain in the southern regions of China,belonging to lineageⅣ,genotypeⅠ,DENV-1.Compared to the seven closest strains from neighboring countries and provinces,a total of 18 amino acid mutations occurred in the coding sequences(CDS)of the new isolated strain,DENV1 HMU-HKU-2.Our data shows that dengue virus is re-emerged in Hainan,and pose new threats for public health.Thus regular molecular epidemiological surveillance is necessary for control and prevention of DENV transmission. | Jiang Du Liyuan Zhang Xiaoyuan Hu Ruoyan Peng Gaoyu Wang Yi Huang Wenqi Wang Kunliang Wu Qiang Wang Haoxiang Su Fan Yang Yun Zhang Chuanning Tang Xiuji Cui Lina Niu Gang Lu Meifang Xiao Yongguo Du Feifei Yin | 2021 | Virologica Sinica2021，36，4： | 2 |
| 9 | Power scaling of diode-pumped Nd: YVO4 lasers 显示文摘 | PENG Xiaoyuan XU Lei ANAND ASUNDI | 2002 | IEEE J Quantum Electron2002，38，9： | 1 |
| 10 | Numerical and experimental study diode-pumped Nd: YVO4 laser with undoped end cap 显示文摘 | Xiaoyuan Peng Lei Xu Anand Asundi | | SPIE0，5460，： | 1 |
| 11 | Study of the mechanical properties of Nd:YVO4 crystal by use of laser interferometry and finite-element analysis显示文摘 | Peng Xiaoyuan Asundi A Chen Yihong | 2001 | Appl Opt2001，40，9： | 1 |
| 12 | A Novel Electrochemical Reactor for Nitrogen and Phosphorus Recovery from Domestic Wastewater显示文摘 | Shiting Ren Mengchen Li Jianyu Sun Yanhong Bian Kuichang Zuo Xiaoyuan Zhang Peng Liang Xia Huang | 2017 | Frontiers of Environmental Science & Engineering2017，11，4： | 1 |
| 13 | Power scaling of diode-pumped Nd:YVO4 Lasers显示文摘 | Lei Xu Anand Asundi | 2002 | IEEE Journal of Quantum Electronics2002，38，9： | 1 |
| 14 | Fluorescent quantum dots: Synthesis, biomedical optical imaging, and biosafety assessment显示文摘 | Xiaoyuan Ji Fei Peng Yiling Zhong Yuanyuan Su Yao He | 2014 | Colloids and Surfaces B: Biointerfaces2014，，： | 1 |
| 15 | Delay-dependent exponential stability criteria for stochastic systems with polytopic-type uncertainties显示文摘This paper considers the problem of delay-dependent exponential stability in mean square for stochastic systems with polytopic-type uncertainties and time-varying delay. Applying the descriptor model transformation and introducing free weighting matrices, a new type of Lyapunov-Krasovskii functional is constructed based on linear matrix inequalities (LMIs), and some new delay-dependent criteria are obtained. These criteria include the delay-independent/rate-dependent and delay-dependent/rate-independent exponential stability criteria. These new criteria are less conservative than existing ones. Numerical examples demonstrate that these new criteria are effective and are an improvement over existing ones. | Yumei LI Xinping GUAN Dan PENG Changchun HUA Xiaoyuan LUO | 2009 | 控制理论与应用(英文版)2009，7，3： | 1 |
| 16 | Studies of digital microscopic holography with applications to microstructure testing显示文摘 | Xu Lei Peng Xiaoyuan Miao Jianmin | 2001 | Appl Opt2001，40，28： | 1 |
| 17 | High power efficient continuous-wave TEM00 intracavity frequency doubled diode-pumped Nd:YLF laser 显示文摘 | Peng Xiaoyuan Xu Lei Asundi A | 2005 | ApplOpt2005，44，5： | 1 |
| 18 | Power scaling of diode-pumped Nd: YVO4 lasers显示文摘 | Peng Xiaoyuan XU Lei ANAND ASUNDI | | 0，，： | 1 |
| 19 | DANMEL:A manually curated reference database for analyzing mobile genetic elements associated with bacterial drug resistance显示文摘Impact statement We have developed a manually curated online reference database,DANMEL(http://gffzzc938d18ffd334cb4h505wcbxqvoup69pu.ffgz.tsg.suse.edu.cn/danmel/),that addresses the lack of accurate dissection and annotation of the genetic structures of mobile genetic elements(MGEs)with genes for drug resistance.DANMEL contains accurately annotated and genetically dissected reference MGEs covering 5 categories and 135 subcategories/subfamilies of MGEs.Further,DANMEL provides a detailed guide on how to precisely annotate MGEs.DANMEL also provides SEARCH/BLAST functions to facilitate finding reference MGEs.Overall,DANMEL will aid researchers to conduct in-depth genetic analysis of sequenced bacterial MGEs with drug-resistance genes and further facilitate a better understanding of bacterial MGEs associated with drug resistance at a genomic level. | Peng Wang Xiaoyuan Jiang Kai Mu Ying Jing Zhe Yin Yujun Cui Cuidan Li Xinhua Luo Fangzhou Chen Ting Yu Zhichen Zhu Yansong Sun Fei Chen Dongsheng Zhou | 2022 | mLife2022，1，4： | 1 |
| 20 | Studies of digital microscopic holography with applications to microstructure testing显示文摘 | Lei Xu Xiaoyuan Peng Jianmin Miao | | 0，，： | 1 |
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