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| 1 | High Frame Rate Contrast-enhanced Ultrasound Helps Differentiate Malignant and Benign Focal Liver Lesions显示文摘Background and Aims:This study aimed to evaluate the diagnostic performance of high frame rate contrast-en-hanced ultrasound(H-CEUS)of focal liver lesions(FLLs).Methods:From July 2017 to June 2019,conventional con-trast-enhanced ultrasound(C-CEUS)and H-CEUS were per-formed in 78 patients with 78 nodules.The characteristics of C-CEUS and H-CEUS in malignant and benign groups and the differences between different lesion sizes(1-3 cm,3-5 cm,or>5 cm)of C-CEUS and H-CEUS were examined.The diagnostic performance of C-CEUS and H-CEUS was ana-lyzed.The chi-square test or Fisher’s exact test was used to assess inter-group differences.The receiver operating characteristic curve was plotted to determine the diagnostic performance of C-CEUS and H-CEUS.Results:There were significant differences in the enhancement area,fill-in direc-tion and vascular architecture between C-CEUS and H-CEUS for both benign and malignant lesions(all p=0.000-0.008),but there were no significant differences in washout results(p=0.566 and p=0.684,respectively).For lesions 1-3 cm in size,the enhancement area,fill-in direction,and vascular architecture on C-CEUS and H-CEUS were significantly dif-ferent(all p=0.000),unlike for lesions 3-5 cm or>5 cm in size.For differentiation of malignant from benign FLLs in the 1-3 cm group,H-CEUS showed sensitivity,specific-ity,accuracy,and positive and negative predictive values of 92.86%,95.0%,96.3%,90.48%and 93.75%,respectively,which were higher than those for C-CEUS(75.0%,70.0%,77.78%,66.67%and 72.91%,respectively).Conclusions:H-CEUS provided more vascular information which could help differentiate malignant from benign FLLs,especially for lesions 1-3 cm in size. | Xiang Fei Peng Han Bo Jiang Lianhua Zhu Wenshuo Tian Maodong Sang Xirui Zhang Yaqiong Zhu Yukun Luo | 2022 | Journal of Clinical and Translational Hepatology2022，10，1： | 8 |
| 2 | Microwave strengthens decomposition of mixed rare earth concentrate: Microwave absorption characteristics显示文摘The potential application of microwave heating technology for processing the mixed rare earth concentrate was systematically investigated by analyzing the microwave absorption characteristics in this study. The complex permittivity was measured through resonant cavity perturbation method. The variations of permittivity, the loss factor, loss tangent and the penetration depth with the increasing temperature were investigated numerically. The results indicate that the permittivity increases as the temperature increases, and temperature has a pivotal effect on it. The mixed concentrate is high loss material at the temperature range from 600 to 800℃ according to theoretical analyses of loss tangent and penetration depth. The results of phase transition analysis prove that the variation of microwave absorption characteristics of mixed concentrate is caused by the changes of crystal and lattice structures.The reflectivity, loss factor and penetration depth of the mixed concentrate were also calculated, and the results indicate that processing the mixed concentrate by microwave heating is of high feasibility and industrial potential. | Yukun Huang Ting'an Zhang Zhihe Dou Guozhi Lv Guihong Han Weijun Peng | 2019 | Journal of Rare Earths2019，37，5： | 5 |
| 3 | Combination of ablative fractional carbon dioxide laser and platelet-rich plasma treatment to improve hypertrophic scars:a retrospective clinical observational study显示文摘Background:Hypertrophic scars are one of the main complications that affect the quality of life of patients after burns.Many methods have been shown to be effective in the treatment of hypertrophic scars,such as ablative fractional CO_(2) laser(AFCL)and platelet-rich plasma(PRP).However,there are few studies on the effect of the combined application of these measures.The purpose of this study was to explore the therapeutic effect of AFCL combined with PRP on hypertrophic burn scars.Methods:A retrospective clinical observation study was conducted on 50 patients with hypertrophic burn scars.The AFCL+PRP group included 31 patients who received AFCL combined with PRP treatment;the AFCL group included 19 patients who received AFCL treatment only.The University of North Carolina 4P Scar Scale(UNC4P)and the Vancouver Scar Scale(VSS)scores that were collected before each treatment were used as indicators of the effectiveness of the previous treatment.The scores recorded at the second,fourth and seventh months were analysed.Results:The demographic data of the 2 groups were not significantly different.Before treatment,therewas no difference in the UNC4P and VSS scores between the 2 groups.Therewas a significant decline in the UNC4P and VSS total scores over 6 months in both groups(p<0.05)and scores in the 2 groups were comparable after 3 and 6 months(p<0.05).UNC4P scores in the AFCL+PRP group decreased from a mean of 8.26 to 2.61(p<0.05)with a concomitant drop in VSS scores from a mean of 11.74 to 6.06(p<0.01).In the AFCL group UNC4P and VSS scores decreased from 7.68 to 4.63(p<0.05)and from 10.89 to 8.16(p<0.05),respectively.The sub-items of these 2 assessments were analysed and the results suggest that AFCL combined with PRP can comprehensively improve scarring.Conclusions:This study shows that PRP is an effective adjunct for AFCL in the treatment of hypertrophic burn scars and that the combination of PRP and AFCL proved to be more useful than AFCL alone.This combination may be a new and effective clinical practice for the treatment of scars.However,larger and higher-level clinical studies are still needed to determine its efficacy and possible mechanisms. | Zhanzhan Dai Xiaozhen Lou Tuo Shen Yu Sun Yongqiang Xiao Xingfeng Zheng Xuexin Wang Yu Peng Yukun Guo Yibin Guo Jiannan Wen He Fang Bing Ma Zhaofan Xia | 2021 | Burns & Trauma2021，9，1： | 4 |
| 4 | PGE2/EP4 skeleton interoception activity reduces vertebral endplate porosity and spinal pain with low-dose celecoxib显示文摘Skeletal interoception regulates bone homeostasis through the prostaglandin E2(PGE2)concentration in bone.Vertebral endplates undergo ossification and become highly porous during intervertebral disc degeneration and aging.We found that the PGE2 concentration was elevated in porous endplates to generate spinal pain.Importantly,treatment with a high-dose cyclooxygenase 2 inhibitor(celecoxib,80 mg·kg−1 per day)decreased the prostaglandin E2 concentration and attenuated spinal pain in mice with lumbar spine instability.However,this treatment impaired bone formation in porous endplates,and spinal pain recurred after discontinuing the treatment.Interestingly,low-dose celecoxib(20 mg·kg−1 per day,which is equivalent to one-quarter of the clinical maximum dosage)induced a latent inhibition of spinal pain at 3 weeks post-treatment,which persisted even after discontinuing treatment.Furthermore,when the prostaglandin E2 concentration was maintained at the physiological level with low-dose celecoxib,endplate porosity was reduced significantly,which was associated with decreased sensory nerve innervation and spinal pain.These findings suggest that low-dose celecoxib may help to maintain skeletal interoception and decrease vertebral endplate porosity,thereby reducing sensory innervation and spinal pain in mice. | Peng Xue Shenyu Wang Xiao Lyu Mei Wan Xialin Li Lei Ma Neil CFord Yukun Li Yun Guan Wenyuan Ding Xu Cao | 2021 | Bone Research2021，9，3： | 2 |
| 5 | Silver nanowire/polymer composite soft conductive film fabricated by large-area compatible coating for flexible pressure sensor array显示文摘Soft conductive films composed of a silver nanowire(AgNW) network, a neutral-pH PEDOT:PSS overcoating layer and a polydimethylsiloxane(PDMS) elastomer substrate are fabricated by large area compatible coating processes. The neutral-pH PEDOT:PSS layer is shown to be able to significantly improve the conductivity,stretchability and air stability of the conductive films. The soft conductive films are patterned using a simple maskless patterning approach to fabricate an 8 x 8 flexible pressure sensor array. It is shown that such soft conductive films can help to improve the sensitivity and reduce the signal crosstalk over the pressure sensor array. | Sujie Chen Siying Li Sai Peng Yukun Huang Jiaqing Zhao Wei Tang Xiaojun Guo | 2018 | Journal of Semiconductors2018，39，1： | 1 |
| 6 | Manageable Multimedia Network Computer显示文摘 | Zhang Yaoxue Peng Yukun Zhou Yuezhi | 2003 | Chinese Journal of Electronics2003，31，12： | 1 |
| 7 | The Second-Order Imaginary Plane Method and Its Calculation Accuracy显示文摘In this paper, the basic principles and mathematical process of the Second-order Imaginary Plane Method (IPM) for modeling the radiative heat transfer are analysed and proved in detail. Through the numerical computation for the real process of the radiative heat transfer using the Second-order IPM,the previous IPM (the first-order), the Analytic Method and the Zone Method, it was shown that the calculation accuracy of the Secondr-order IPM is much higher than that of the first-order IPM, and its demand to computer capacity and time consuming is much lower than that of the Zone Method or the Analytic Method. It is verilied that the method is more effective and has a higher accuracy for modeling radiative heat transfer in engineering. | Dong Peng Chen Xiaodong Zhu Tong Qin Yukun(Dept. of Power Engineering, Haxbin Institute of Technology, Harbin, 150001, China) | 1997 | Journal of Thermal Science1997，6，2： | 1 |
| 8 | Onthe mechanisms of the recurvature of super typhoon Megi显示文摘 | PENG SHIQIU QIAN YUKUN LAI ZHIJUAN 2014 | 2014 | Scientific Reports2014，4，12： | 1 |
| 9 | Interfacial Reinitiation of Free Radicals Enables the Regeneration of Broken Polymeric Hydrogel Actuators显示文摘Living organisms,from plants to animals,have inspired and guided the design and fabrication of polymeric hydrogels with biomimetic morphology,shape deformation,and actuation behavior.However,the existing polymeric hydrogels are fragile and vulnerable,which seriously hinders further application.Therefore,endowing hydrogels with a biomimetic self-growth property and regenerating the macroscopic shape of hydrogels after they suffer significant damage are highly desirable for the next generation of adaptive biomimetic hydrogels.Inspired by the tail regeneration of geckos,we herein report an efficient and universal strategy of interfacial diffusion polymerization(IDP),which can regenerate the polymeric layer at a solid–liquid interface,thereby growing new hydrogels on the existing hydrogel layers.Through changing the solvent viscosity and/or monomer type of the hydrogel precursor,diverse new hydrogels have been regenerated to endow the initial hydrogels with additional fluorescent functions and/or actuating properties.Due to the high efficiency and universality of IDP,an injured hydrogel actuator can be repaired,regenerated,and recovered to its initial condition,even after suffering severe damage such as cutting or piercing.We believe that the regeneration strategy of polymeric hydrogels will inspire the design of biomimetic materials and motivate the fabrication of the next generation of soft robots with adaptive and multifunctional properties. | Baoyi Wu Huanhuan Lu Yukun Jian Dachuan Zhang Yu Peng Jie Zhuo Xiaoxia Le Jiawei Zhang Patrick Théato Tao Chen | 2023 | CCS Chemistry2023，5，3： | 0 |
| 10 | Preparation of polyclonal antibody highly specific for mouse BRD7 protein and its application显示文摘 | Heran Wang Ran Zhao Ming Zhou Chi Guo Yukun Liu Shihe Jiang Xiayu Li Wei Xiong Jian Ma Shuping Peng Xiaoling Li David C. Schmitt Ming Tan Guiyuan Li | 2014 | Acta Biochimica et Biophysica Sinica2014，46，2： | 0 |
| 11 | Spontaneous polarization enhanced bismuth ferrate photoelectrode:fabrication and boosted photoelectrochemical water splitting property显示文摘In this paper,the fabrication of a highly orientated Bi_(2)Fe_(4)O_(9)(BFO)photoelectrode in the presence of two-dimensional(2D)graphene oxide(GO)was reported.It was found that the GO can be used as a template for controlling the growth of BFO,and the nanoplate composites of BFO/reduced graphene oxide(RGO)with a high orientation can be fabricated.The thickness of the nanoplates became thinner as the ratio of GO increased.As a result,the ferroelectric spontaneous polarization unit arranges itself in the space in a periodic manner,leading to the formation of a polarization field along a special direction.Therefore,the created built-in electric field of the nanoplate composites of BFO/RGO is improved upon the increase of the amount of RGO.As expected,carrier separation is enhanced by the built-in electric field,therefore substantially enhancing the photoelectrochemical(PEC)activity of water splitting compared to pure BFO under the irradiation of visible-light. | Yan ZHANG Yukun ZHU Yanhua PENG Xiaolong YANG Jian LIU Wei JIAO Jianqiang YU | 2021 | Frontiers in Energy2021，15，3： | 0 |
| 12 | STRUCTURE AND SURFACE CONDITION OF ULTRAFINE AI PARTICLES显示文摘The crystal habit,crystalline structure,surface condition and composition of the ultrafine Alparticles prepared by inert gas evaporation method were studied in detail by means of highresolution transmission electron microscope,X-ray diffraction and X-ray photo-electronspectrum.The results indicate that the ultrafine Al particles prepared in high pure inert gasare of clear crystal habits,single crystal in a large majority and fcc crystalline structure witha0=0.405 nm.It is also found on the surface of the Al particles that there is a layer of amor-phous Al2O3 with 2 nm average thickness,which could protect the particles against oxidizingfurther.Therefore,the ultrafine Al particles prepared by the inert gas evaporation method arevery stable in atmosphere. | SUN Xiukui CHEN Wenxiu XU Jian FAN Xueshu WEI Wenduo State Key Laboratory of Rapidly Solidified Non-Equilibrium Alloys,Institute of Metal Research,Academia Sinica,Shenyang,ChinaWU Yukun PENG Yingguo Laboratory of Atomic Imaging of Solids,Institute of Metal Research,Academia Sinica,Shenyang,China Associate Professor,Institute of Metal Research,Academia Sinica,Shenyang 110015,China | 1992 | Acta Metallurgica Sinica(English Letters)1992，5，6： | 0 |
| 13 | First experimental comparisons of laser-plasma interactions between spherical and cylindrical hohlraums at SGⅢ laser facility显示文摘We present our recent laser-plasmas instability(LPI)comparison experiment at the SGIII laser facility between the spherical and cylindrical hohlraums.Three kinds of filling are considered:vacuum,gas-filling with or without a capsule inside.A spherical hohlraum of 3.6 mm in diameter,and a cylindrical hohlraum of 2.4 mm?4.3 mm are used.The capsule diameter is 0.96 mm.A flat-top laser pulse with 3 ns duration and up to 92.73 kJ energy is used.The experiment has shown that the LPI level in the spherical hohlraum is close to that of the outer beam in the cylindrical hohlraum,while much lower than that of the inner beam.The experiment is further simulated by using our 2-dimensional radiation hydrodynamic code LARED-Integration,and the laser back-scattering fraction and the stimulated Raman scatter(SRS)spectrum are post-processed by the high efficiency code of laser interaction with plasmas HLIP.According to the simulation,the plasma waves are strongly damped and the SRS is mainly developed at the plasma conditions of electron density from 0.08 n_(c) to 0.1 n_(c) and electron temperature from 1.5 keV to 2.0 keV inside the hohlraums.However,obvious differences between the simulation and experiment are found,such as that the SRS back-scattering is underestimated,and the numerical SRS spectrum peaks at a larger wavelength and at a later time than the data.These dif-ferences indicate that the development of a 3D radiation hydrodynamic code,with more accurate physics models,is mandatory for spherical hohlraum study. | Yaohua Chen Zhichao Li Xufei Xie Chunyang Zheng Chuanlei Zhai Liang Hao Dong Yang Wenyi Huo Guoli Ren Jie Liu Xiaoshi Peng Tao Xu Yulong Li Sanwei Li Zhiwen Yang Liang Guo Lifei Hou Yonggang Liu Huiyue Wei Xiangming Liu Weiyi Cha Yukun Li Keli Deng Zheng Yuan Xiayu Zhan Haijun Zhang Baibin Jiang Wei Zhang Kai Du Xuewei Deng Yongkun Ding Xiaofeng Wei Wanguo Zheng Xiaodong Chen Xiantu He Ke Lan | 2017 | Matter and Radiation at Extremes2017，2，2： | 0 |
| 14 | The combined effects of biomass and temperature on maximum specific ammonia oxidation rate in domestic wastewater treatment显示文摘Measurement and predicted variations of ammonia oxidation rate(AOR)are critical for the optimization of biological nitrogen removal,however,it is difficult to predict accurate AOR based on current models.In this study,a modified model was developed to predict AOR based on laboratoryscale tests and verified through pilot-scale tests.In biological nitrogen removal reactors,the specific ammonia oxidation rate(SAOR)was affected by both mixed liquor volatile suspended solids(MLVSS)concentration and temperature.When MLVSS increased 1.6,4.2,and 7.1-fold(1.3‒8.9 g/L,at 20℃),the measured SAOR decreased by 21%,49%,and 56%,respectively.Thereby,the estimated SAOR was suggested to modify when MLVSS changed through a power equation fitting.In addition,temperature coefficient(θ)was modified based on MLVSS concentration.These results suggested that the prediction of variations ammonia oxidation rate in real wastewater treatment system could be more accurate when considering the effect of MLVSS variations on SAOR. | Yukun Zhang Shuying Wang Shengbo Gu Liang Zhang Yijun Dong Lei Jiang Wei Fan Yongzhen Peng | 2021 | Frontiers of Environmental Science & Engineering2021，15，6： | 0 |
| 15 | 6-5 Operation of HWRs for C-ADS Injector显示文摘There are two types of HWR cavities have been developed in IMP for C-ADS Injector.HWR010s have been used to accelerate proton from 2.1 MeV to 10 MeV.There are 12 HWR010s assembled in two CMs.The taper type HWR015s have been used to accelerate proton from 10MeV to 18.5 MeV.There are 5 HWRs assembled in the third CM.Proton beam has been accelerated to 26 MeV by HWR010,HWR015 and Spoke021 in June 2017.The beam has been accelerated to 18.5 MeV by HWR010 and HWR015.The CMs in the tunnel are shown in Fig.1. | Yue Weiming Zhang Shenghu Li Yongming Chang Wei Jiang Tiancai Zhang Shengxue Gao Zheng Wang Ruoxue Huang Shichun Pan Feng Chen Long Li Chunlong Song Yukun Guo Hao Xiong Pingran Cong Zhang Tan Teng Wan Yuqin Niu Xiaofei Bai Feng Hu Chuanfei Zhang Peng Liu Lubei Huang Yulu Zhao Yugang Guo Xiaohong You Zhiming Zhang Junhui Huang Guirong He Yuan | 2016 | IMP & HIRFL Annual Report2016，，1： | 0 |
| 16 | Bead-like cobalt-nitrogen co-doped carbon nanocage/carbon nanofiber composite:A high-performance oxygen reduction electrocatalyst for zinc-air batteries显示文摘Proper regulation of metal-nitrogen carbon(M-N-C)materials derived from zeolitic imidazolate frameworks(ZIFs)is essential to enhance the oxygen reduction reaction(ORR)performance.However,most of the reports focus on the component regulation,and the structure regulation of ZIFs-derived M-N-C materials by a simple preparation method has been barely reported.Herein,using a one-step electrospinning method with subsequent pyrolysis,we have prepared a bead-like cobalt-nitrogen co-doped carbon nanocage/carbon nanofiber(Co-N-C/CNF)composite electrocatalyst with the porous carbon nanocages arranged one by one in the highly conductive carbon nanofibers.Profiting from the fully exposed active sites and improved conductivity,the Co-NC/CNF catalyst exhibits an excellent ORR performance even surpassing the commercial Pt/C catalyst.Density functional theory(DFT)results demonstrate that the CoNP-N1-C2 active sites on Co-N-C/CNF make the core contribution to the improvement of ORR properties.Moreover,the zinc-air battery(ZAB)based on the Co-N-C/CNF catalyst also shows outstanding discharge performance.This study provides a new strategy for the preparation and structural design for ZIFs-derived M-N-C materials as efficient ORR catalysts. | Bo Zhang Yige Zhao Lu Li Yukun Li Jin Zhang Guosheng Shao Peng Zhang | 2023 | Nano Research2023，16，1： | 0 |
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