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| 1 | High Frame Rate Contrast-enhanced Ultrasound Helps Differentiate Malignant and Benign Focal Liver Lesions显示文摘Background and Aims:This study aimed to evaluate the diagnostic performance of high frame rate contrast-en-hanced ultrasound(H-CEUS)of focal liver lesions(FLLs).Methods:From July 2017 to June 2019,conventional con-trast-enhanced ultrasound(C-CEUS)and H-CEUS were per-formed in 78 patients with 78 nodules.The characteristics of C-CEUS and H-CEUS in malignant and benign groups and the differences between different lesion sizes(1-3 cm,3-5 cm,or>5 cm)of C-CEUS and H-CEUS were examined.The diagnostic performance of C-CEUS and H-CEUS was ana-lyzed.The chi-square test or Fisher’s exact test was used to assess inter-group differences.The receiver operating characteristic curve was plotted to determine the diagnostic performance of C-CEUS and H-CEUS.Results:There were significant differences in the enhancement area,fill-in direc-tion and vascular architecture between C-CEUS and H-CEUS for both benign and malignant lesions(all p=0.000-0.008),but there were no significant differences in washout results(p=0.566 and p=0.684,respectively).For lesions 1-3 cm in size,the enhancement area,fill-in direction,and vascular architecture on C-CEUS and H-CEUS were significantly dif-ferent(all p=0.000),unlike for lesions 3-5 cm or>5 cm in size.For differentiation of malignant from benign FLLs in the 1-3 cm group,H-CEUS showed sensitivity,specific-ity,accuracy,and positive and negative predictive values of 92.86%,95.0%,96.3%,90.48%and 93.75%,respectively,which were higher than those for C-CEUS(75.0%,70.0%,77.78%,66.67%and 72.91%,respectively).Conclusions:H-CEUS provided more vascular information which could help differentiate malignant from benign FLLs,especially for lesions 1-3 cm in size. | Xiang Fei Peng Han Bo Jiang Lianhua Zhu Wenshuo Tian Maodong Sang Xirui Zhang Yaqiong Zhu Yukun Luo | 2022 | Journal of Clinical and Translational Hepatology2022，10，1： | 8 |
| 2 | Proteomic identification of new diagnostic biomarkers of early-stage cutaneousmycosis fungoides显示文摘Dear editor,Mycosis fungoides(MF),the most common subtype of cutaneous T cell lymphoma,is a rare disease[1,2].Patients with early-stageMF have a 5-year overall survival between 88%and 100%[3].In patients with advanced MF,the skin may present with tumors and erythroderma,and the median survival of patients with lymph node and visceral metastasis is 13 months[4].Therefore,it is important to achieve an early diagnosis to improve prognosis[5]. | Ling Leng Zhaorui Liu Jie Ma Shiyu Zhang Yukun Wang Luye Lv Yunping Zhu Dunqin Gao Yujie Wang Juncheng Wang Yuehua Liu Jie Liu | 2022 | Cancer Communications2022，42，6： | 4 |
| 3 | Hydroformylation of 1-Octene over Nanotubular TiO2-supported Amorphous Co-B Catalysts显示文摘 | SHI Yukun HU Xiaojing ZHU Baolin ZHANG Shoumin HUANG Weiping | 2015 | Chemical Research in Chinese Universities2015，31，5： | 3 |
| 4 | Hierarchical red phosphorus incorporated TiO_(2) hollow sphere heterojunctions toward superior photocatalytic hydrogen production显示文摘Solar-to-hydrogen conversion through photocatalysis is a sustainable and promising strategy for storing solar energy.Recently,elemental red phosphorus(RP)with broad light absorption has been recognized as a potential candidate for photocatalytic hydrogen evolution,while challenges remain due to the rapid recombination of photogenerated carriers.In this work,RP modified TiO_(2)hollow spheres were designed and fabricated through the chemical vapor deposition method.The optimal hydrogen production rate reaching 215.5μmol/(g h)over TiO_(2)@RP heterostructure was obtained under simulated solar light irradiation.Experimental results evidenced that the hollow sphere structure and RP light absorber extended light absorption ability,and the heterostructure induced interfacial charge migration facilitated photoinduced charge separation,which benefited the photocatalytic hydrogen production performance. | Guiqing Huang Wanneng Ye Chunxiao Lv Denys S.Butenko Chen Yang Gaolian Zhang Ping Lu Yan Xu Shuchao Zhang Hongwei Wang Yukun Zhu Dongjiang Yang | 2022 | Journal of Materials Science & Technology2022，，13： | 3 |
| 5 | On the technologies of Hα imaging spectrograph for the CHASE mission显示文摘The Hα imaging spectrograph(HIS) is the scientific payload of the first solar space mission, the Chinese Hα solar explorer(CHASE), supported by the China National Space Administration(CNSA). The CHASE/HIS achieves, for the first time in space, Hα spectroscopic observations with high spectral and temporal resolutions. Separate channels for the raster scanning mode(RSM) and continuum imaging mode(CIM) are integrated into one, and a highly integrated design is achieved through multiple folding of the optical path and ultra-light miniaturized components. The design of HIS implements a number of key technologies such as high-precision scanning of the optical field of view(FOV), high-precision integrated manufacturing inspection, a large-tolerance pre-filter window, and full-link solar radiation calibration. The HIS instrument has a pixel spectral resolution of 0.024 ? and can complete a full-Sun scanning within 46 s. | Qiang Liu Hongjiang Tao Changzheng Chen Chengshan Han Zhe Chen Gui Mei Liang Yang Qinglong Hu Hongwei Xin Xiansheng Li Hongyu Guan Donglin Xue Mingchao Zhu Changhong Hu Qinghua Ha Yukun He Cheng Fang Chuan Li Zhen Li | 2022 | Science China(Physics,Mechanics & Astronomy)2022，65，8： | 2 |
| 6 | Essential role of Msx1 in regulating anterior-posterior patterning of the secondary palate in mice显示文摘Development of the secondary palate displays molecular heterogeneity along the anterior-posterior axis;however, the underlying molecular mechanism remains largely unknown. MSX1 is an anteriorly expressed transcription repressor required for palate development. Here, we investigate the role of Msx1 in regional patterning of the secondary palate. The Wnt1-Cre-mediated expression of Msx1(Rosa Msx1^(Wnt1-Cre))throughout the palatal mesenchyme leads to cleft palate in mice, associated with aberrant cell proliferation and cell death. Osteogenic patterning of the hard palate in Rosa Msx1^(Wnt1-Cre)mice is severely impaired, as revealed by a marked reduction in palatine bone formation and decreased expression of the osteogenic regulator Sp7. Overexpression and knockout of Msx1 in mice show that the transcription repressor promotes the expression of the anterior palate-specific Alx1 but represses the expression of the medialposterior palate genes Barx1, Meox2, and Tbx22. Furthermore, Tbx22 constitutes a direct Msx1 target gene in the secondary palate, suggesting that Msx1 can directly repress the expression of medial-posterior specific genes. Finally, we determine that Sp7 is downstream of Tbx22 in palatal mesenchymal cells,suggesting that a Msx1/Tbx22/Sp7 axis participates in the regulation of palate development. Our findings unveil a novel role for Msx1 in regulating the anterior-posterior growth and patterning of the secondary palate. | Shicheng Zhu Hanjing Song Liangjun Zhong Suman Huo Yukun Fang Wanxin Zhao Xueqin Yang Zhong-Min Dai Rui He Mengsheng Qiu Zunyi Zhang Xiao-Jing Zhu | 2022 | Journal of Genetics and Genomics2022，49，1： | 2 |
| 7 | Record power and efficient mid-infrared supercontinuum generation in germania fiber with high stability显示文摘We report the demonstration of a mid-infrared(MIR)supercontinuum(SC)laser delivering a record-breaking average output power of more than 40 W with a long-wavelength edge up to 3.5μm.The all-fiberized configuration was composed of a thulium-doped fiber amplifier system emitting a broadband spectrum covering 1.9–2.6μm with pulse repetition rate of 3 MHz,and a short piece of germania fiber.A 41.9 W MIR SC with a whole spectrum of 1.9–3.5μm was generated in a piece of 0.2-m-long germania fiber,with a power conversion efficiency of 71.4%.For an even shorter germania fiber(0.1 m),an SC with even higher output power of 44.9 W(corresponding to a conversion efficiency of 76.5%)was obtained,but the energy conversion toward the long-wavelength region was slightly limited.A continuous operation for 1 hour with output power of 32.6 W showed outstanding power stability(root mean square 0.17%)of the obtained SC laser.To the best of the authors’knowledge,for the first time,this work demonstrates the feasibility of germania fiber on generating a 40-W level MIR SC with high efficiency and excellent power stability,paving the way to real applications requiring high power and high reliability of MIR SC lasers. | Linyong Yang Yukun Yang Bin Zhang Xiran Zhu Desheng Zhao Shuailin Liu Jing Hou | 2022 | High Power Laser Science and Engineering2022，10，6： | 1 |
| 8 | Displace- ment Self-sensing of Bearingless Switched Reluctance Rotors Based on LS-SVM显示文摘 | Zhu Zhiying Sun Yukun Huang Yonghong | 2012 | Przeglad Elektrotechniczny2012，88，12： | 1 |
| 9 | 显示文摘 | Zhengying Pan Yukun Ho | 1999 | Nuclear In struments and Methods in Physics Research B1999，153，： | 1 |
| 10 | Emergency contrast-enhanced ultrasonography for pancreatic injuries in blunt abdominal trauma显示文摘 | Faqin Lv Jie Tang Yukun Luo Yongkang Nie Tong Liang Ziyu Jiao Zhihong Zhu Tanshi Li | 2014 | La radiologia medica2014，，： | 1 |
| 11 | The Second-Order Imaginary Plane Method and Its Calculation Accuracy显示文摘In this paper, the basic principles and mathematical process of the Second-order Imaginary Plane Method (IPM) for modeling the radiative heat transfer are analysed and proved in detail. Through the numerical computation for the real process of the radiative heat transfer using the Second-order IPM,the previous IPM (the first-order), the Analytic Method and the Zone Method, it was shown that the calculation accuracy of the Secondr-order IPM is much higher than that of the first-order IPM, and its demand to computer capacity and time consuming is much lower than that of the Zone Method or the Analytic Method. It is verilied that the method is more effective and has a higher accuracy for modeling radiative heat transfer in engineering. | Dong Peng Chen Xiaodong Zhu Tong Qin Yukun(Dept. of Power Engineering, Haxbin Institute of Technology, Harbin, 150001, China) | 1997 | Journal of Thermal Science1997，6，2： | 1 |
| 12 | Numerical Study of the Effect of Imaginary Circle Diameter and Initial Flow Field on the Aerodynamic Field in a Tangentially Fired Furnace显示文摘In this paper, the effect of the imaginary circle diameter opi and the initial flow field on the aerodynamic field in a tangentially fired furnace was studied by numerical simulation and experiments in the cold model. Results show that merely reducing the imaginary circle diameter rki can not significantly reduce the rotatiollal diameter op in the range considered. The flow still rotates coullter-clockwise stably and does not change rotation direction when the direction of all jet axes are defiected suddenly to the opposite rotation direction by up to 5.4' in a countereclockwise llow field. It is the first time that the numerical sAnulation results were obtained which agreed quite well with this experimental phenomena qualitatively. The experimental data, i.e., the rotational diameter & and the maximum velocity on the syrnmetric central line of fUrnace Vm, are only a bit larger than the simulation results. It is shown that the initial flow field has an important influence on the aerodynamic field in the furnace. Other measures have to be taken as wel1 in order to reduce & to resist slagging and high temperature corrosion of furnace tubes. Moreover, a new kind of grid arrangement was proposed in this paper, which can reduce effectively the false diffosion at the exit zone of burner. | Zhu Tong Sun Shaozeng Xia Chunyi An Baizeng Wu Shaohua Qin Yukun(School of Energy Science and Engineering, Harbin Institute of Technology, 150001, Harbin, China)Ma Xichen(Haxbin Boiler Works) | 1997 | Journal of Thermal Science1997，6，2： | 1 |
| 13 | Preparation,characterization,and antifungal evaluation of a new type of aminourea chitooligosaccharide derivatives显示文摘Phytopathogenic fungi cause heavy negative impact on the agricultural economy,but most existing fungicides are toxic and pose a threat to both human health and environments.A green and efficient fungicide is urgently needed.Chitooligosaccharides(COSs),the degradation products of natural polysaccharide chitosan,are nontoxic and biodegradable antifungal substances.In this study,a novel type of aminourea chitooligosaccharide derivatives(AUCOS)was synthesized by successively grafting a hydrazine group and an amine-carbonyl group onto a chitooligosaccharide backbone to enhance the antifungal capability of COSs.The structures of the target compounds were identified by FTIR,1H NMR,and 13C NMR,and the degree of substitution of each product was calculated from the results of the elemental analysis.The antifungal activities of the prepared chitooligosaccharide derivatives against Fusarium solani,Verticillium albo-atrum and Phytophthora capsici were tested in vitro.The AUCOSs had better inhibitory efficiencies against the three plant pathogen fungi than that of chitooligosaccharide,of which aminourea chitooligosaccharide 2(AUCOS2)was the most promising antifungal compound,whose highest inhibition rates were 60.12%,82.95%,and 85.23%against F.solani,V.albo-atrum and P.capsici,respectively.The synthesized derivatives have good application prospects in crop protection and deserve further research. | ZHU Jun LIU Song QIN Yukun XING Rong’e YU Huahua CHEN Xiaolin LI Pengcheng | 2020 | Journal of Oceanology and Limnology2020，38，3： | 1 |
| 14 | Effects of 1,3-dichloropropene as a methyl bromide alternative for management of nematode, soil-borne disease, and weed in ginger ( Zingiber officinale ) crops in China显示文摘 | Kang Qiao Yukun Zhu Hongyan Wang Xiaoxue Ji Kaiyun Wang | 2011 | Crop Protection2011，，： | 1 |
| 15 | An improved social force model (ISFM)-based crowd evacuation simulation method in virtual reality with a subway fire as a case study显示文摘Crowd evacuation simulation using virtual reality(VR)is significant for digital emergency response construction.However,existing evacuation simulation studies suffer from poor adaptation to complex environments,inefficient evacuations,and poor simulation effects and do not fully consider the impacts of specific disaster environments on crowd evacuation.To more realistically express the crowd evacuation results obtained under the influence offire environments and the subjective consciousness of pedestrians in subway stations,we designed a dynamic pedestrian evacuation path planning method under multiple constraints,analysed the influences of an‘environmental role’and a‘subjective initiative’on crowd evacuation,established an improved social force model(ISFM)-based crowd evacuation simulation method in VR,developed a prototype system and conducted experimental analyses.The experimental results show that the crowd evacuation time of the ISFM is affected by the disaster severity.In simulation experiments without disaster scenarios,the improved model’s crowd evacuation efficiency improved by averages of 12.53%and 15.37%over the commercial Pathfinder software and the original social force model,respectively.The method described herein can effectively support real-time VR crowd evacuation simulation under multiexit and multifloor conditions and can provide technical support for emergency evacuation learning and management decision analyses involving subwayfires. | Jinbin Zhang Jun Zhu Pei Dang Jianlin Wu Yuxuan Zhou Weilian Li Lin Fu Yukun Guo Jigang You | 2023 | International Journal of Digital Earth2023，16，1： | 1 |
| 16 | Review of intelligent well technology显示文摘Intelligent well technology is an oil and gas well optimization completion technology integrated with underground real-time monitoring,data analysis decision-making and remote control of downhole tools.It's of great significance to the transformation and innovation of China's oil and gas development projects.The author of this paper expounds the definition,principle,composition and characteristics of intelligent well technology,and introduces the development status quo of intelligent well technology abroad,including mature intelligent well system,key technology research of intelligent well and its application technology.After the introduction to the related technology research of intelligent well in China,the author puts forward some opinions on the development of our own complete intelligent well system. | Ma Huiyun Yu Chenggang Dong Liangliang Fu Yukun Shuai Chungang Sun Hanwen Zhu Xiaohua | 2020 | Petroleum2020，6，3： | 1 |
| 17 | Quantitative Characterization and Genesis Analysis of Complex Modals of Pore Structure in Alluvial-Fan Sandy Conglomerate Reservoirs显示文摘新疆油田冲积扇砂砾岩储层岩石类型多样,颗粒大小混杂,分选极差,储层孔隙结构具有典型的多种模态特征,即单模态、双模态与复模态等。利用铸体薄片、压汞、恒速压汞资料定量表征了七东1区砂砾岩储层复杂模态孔隙特征以及连通特征,利用多元回归分析法建立复杂模态孔隙结构储层的识别模型。以此为基础,分析了冲积扇砂砾岩储层孔隙结构复杂模态成因机制。研究表明:单模态储层主要以Ⅰ类储层为主,双模态储层以Ⅱ、Ⅲ类储层为主,复模态储层以Ⅲ类储层为主。从单模态类型到复模态孔喉组合类型,孔隙发育由好变差,由连通较好的网状到连通较差的星点状,面孔率降低,平均孔径减小,孔喉配位数减小。利用已有147块样品统计发现,七东1区下克拉玛依组储层中单模态储层占19%、双模态储层占48%、复模态储层占33%。由此提出不同模态判断标准,建立了储层孔隙结构预测模型,揭示了储层构型、成岩后作用及注水(聚)开发中后期的系列变化等多因素是导致形成复杂模态的原因。 | Senlin Yin Juan Chen Yukun Chen Xiaoguang Wang Xuzhuang Zhu | 2017 | 石油天然气学报2017，39，3： | 0 |
| 18 | Spontaneous polarization enhanced bismuth ferrate photoelectrode:fabrication and boosted photoelectrochemical water splitting property显示文摘In this paper,the fabrication of a highly orientated Bi_(2)Fe_(4)O_(9)(BFO)photoelectrode in the presence of two-dimensional(2D)graphene oxide(GO)was reported.It was found that the GO can be used as a template for controlling the growth of BFO,and the nanoplate composites of BFO/reduced graphene oxide(RGO)with a high orientation can be fabricated.The thickness of the nanoplates became thinner as the ratio of GO increased.As a result,the ferroelectric spontaneous polarization unit arranges itself in the space in a periodic manner,leading to the formation of a polarization field along a special direction.Therefore,the created built-in electric field of the nanoplate composites of BFO/RGO is improved upon the increase of the amount of RGO.As expected,carrier separation is enhanced by the built-in electric field,therefore substantially enhancing the photoelectrochemical(PEC)activity of water splitting compared to pure BFO under the irradiation of visible-light. | Yan ZHANG Yukun ZHU Yanhua PENG Xiaolong YANG Jian LIU Wei JIAO Jianqiang YU | 2021 | Frontiers in Energy2021，15，3： | 0 |
| 19 | Reliable folding of hybrid tetrapeptides into shortβ-hairpins显示文摘Five hybrid tetrapeptides,each consisting a central dipeptide segment ofα-amino acid residues flanked by two aromaticγ-amino acid residues,are found to fold into well-definedβ-hairpin conformations as shown by NMR,computational study,and X-ray structures.The turn loop of thisβ-hairpin motif accommodates different two-residueα-amino acid sequences from the highly flexible Gly-Gly,to the more restricted D-Pro-Gly.The presence ofα-amino acid side chains enhances the stabilities of theβ-hairpins with the exception of D-Pro-Gly-which results in destabilization.Based on this hairpin/turn motif,a variety of different dipeptide sequences ofα-amino acids which rarely occur inβ-turns can be introduced and presented as two-residue loops. | Xue-Yi Sun Yulong Zhong Yao-Hua Li Daniel P.Miller Sagar Buttan Xiang-Xiang Wu Yukun Zhang Quan Tang Hong-Wei Tan Jin Zhu Rui Liu Eva Zurek Zhong-Lin Lu Bing Gong | 2022 | Chinese Chemical Letters2022，33，1： | 0 |
| 20 | A 16-QAM 45-Gbps 7-m Wireless Link Using InP HEMT LNA and GaAs SBD Mixers at 220-GHz-Band显示文摘This paper presents a 220-GHz-band 7-m wireless link with a 45-Gbps transmission data rate by using 16 quadrature amplitude modulation(16-QAM).Super-heterodyne transceiver modules are developed for transmission and reception of the modulated signals,which consist of a Schottky barrier diodes(SBD)based sub-harmonic mixer(SHM),an InP HEMT low noise amplifier(LNA),a waveguide band-pass filter(BPF),and a 108-GHz local oscillator(LO)multiplier chain.The transmitter features a peak transmit power of 1.41 dBm,and the IF frequency varies from 5 GHz to 20 GHz.Besides,the receiver features a conversion gain of 9.3 dB in average and a noise temperature of 3052.8 K.The measured results indicate that the transceiver modules enable data transmission of a 45-Gbps 16-QAM signal with Signal-Noise-Ratio(SNR)from 11.59 dB to 15.36 dB in a 7-m line-of-sight channel. | Yukun Li Yong Zhang Chengkai Wu Jianhan Cui Huali Zhu Bo Yan | 2021 | China Communications2021，18，5： | 0 |
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