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| 1 | Chinese Society of Clinical Oncology (CSCO) diagnosis and treatment guidelines for head and neck cancer 2018 (English version)显示文摘Contents1. Principles of diagnosis and treatment of head and neck cancer2. Diagnosis principles of head and neck cancer2.1 Image diagnosis2.2 Pathological diagnosis2.3 Staging3. Treatment principles of early and locally advanced head and neck squamous cell carcinoma3.1 Treatment of oral cancer3.1.1 Treatment of early oral cancer3.1.2 Treatment of locally advanced oral cancer. | Pingzhang Tang Ye Guo Chaosu Hu Zhengang Xu Chenping Zhang Liang Zhou | 2019 | Chinese Journal of Cancer Research2019，31，1： | 15 |
| 2 | CMTM4 inhibits cell proliferation and migration via AKT, ERK1/2,and STAT3 pathway in colorectal cancer显示文摘CMTM4(CKLF-like MARVEL transmembrane domain containing 4),a potential tumor suppressor gene,is involved in several types of malignancies.It has been reported to be downregulated and exhibit anti-tumorigenic activities by regulating cell growth and cell cycle in clear cell renal cell carcinoma.It has also been identified as a tumor suppressor in hepatocellular carcinoma(HCC),and its negative expression is a risk factor for poor prognosis of HCC patients.In the present study,an integrated bioinformatics analysis based on The Cancer Genome Atlas(TCGA)database showed that CMTM4 was frequently reduced in colorectal cancer(CRC)and high expression of CMTM4 was associated with increased overall survival rates.Based on these findings,we adopted gain-of-function and lost-of-function strategies using SW480 and HT29 CRC cell lines which have relatively low and high endogenous CMTM4 levels,respectively.We observed impeded cell proliferation and migration upon overexpression of CMTM4 in SW480 cells,and the opposite effects were observed upon knockdown of CMTM4 in HT-29 cells.Cell signaling pathways essential for CRC progression were then examined,and the phosphorylation levels of AKT,ERK1/2,and STAT3 were found to be decreased by CMTM4 overexpression in SW480 cells and elevated by CMTM4 silencing in HT29 cells.Their inhibitors were used to validate that the three signaling pathways contributed to the inhibitory effects of CMTM4 on CRC cells.Taken together,our results suggest that CMTM4 plays a tumor suppressive role in CRC. | Hui Xue Ting Li Pingzhang Wang Xiaoning Mo Hejun Zhang Shigang Ding Dalong Ma Wenping Lv Jing Zhang Wenling Han | 2019 | Acta Biochimica et Biophysica Sinica2019，51，9： | 5 |
| 3 | Stable and optimal adaptive fuzzy control of complex systems using fuzzy dynamic model 显示文摘 | Qu Sun Renhou Li PingZhang | 2003 | Fuzzy Sets and Systems2003，，133： | 1 |
| 4 | Primary tracheal tumours: 21 years of experience at Peking Union Medical College, Beijing, China 显示文摘 | Zhengjaiang L Pingzhang T Dechao Z | 2008 | J Laryngol Otol2008，122，11： | 1 |
| 5 | A study on p16, PRb, cdk4 and CyclinD1 expression in non-small cell lung cancers 显示文摘 | Lingfei K PingZhang Y Zhengguo L | 1998 | Cancer Lett1998，130，12： | 1 |
| 6 | A study on P16,pRB,cdk4 and cyclinD1 expression in non-small cell lung cancer显示文摘 | Pingzhang Y Zhenguo L | 1998 | Cancer Letters1998，130，12： | 1 |
| 7 | Management and outcome of cervical lymph node metastases of unknown primary sites: a retrospective study显示文摘 | Yalin Y Pingzhang T Smith GI | 2002 | Br J Oral Maxillofac Surg2002，40，6： | 1 |
| 8 | Confocal endomicroscopy for in vivo detection of microvascular architecture in normal and malignant lesions of upper gastrointestinal tract显示文摘 | HongLiu Yan‐QingLi TaoYu You‐AnZhao Jian‐PingZhang Jian‐NaZhang Yu‐TingGuo Xiang‐JunXie Ting‐GuoZhang Paul VDesmond | 2007 | Journal of Gastroenterology and Hepatology2007，，： | 1 |
| 9 | Surgical management of patients with insulinomas: Result of 292 cases in a single institution显示文摘 | Yu‐peiZhao Han‐xiangZhan Tai‐pingZhang LinCong Meng‐huaDai QuanLiao Li‐xingCai | 2011 | Oncol2011，，2： | 1 |
| 10 | A study on p16, pRB,cdk4 and cyclinD1 expression in non - small cell lung cancer 显示文摘 | Lingfei K Pingzhang Y Zhenguo L | 1998 | Cancer Letters1998，130，： | 1 |
| 11 | Dark purple nec- tar as a foraging signal in a bird-pollinated Himalayan plant 显示文摘 | Feng Pingzhang Xiang Haieai Hong Wang | 2012 | New Phytologist2012，193，1： | 1 |
| 12 | Understanding information related fields: A conceptual framework显示文摘 | PingZhang Robert I.Benjamin | 2007 | J Am Soc Inf Sci2007，，13： | 1 |
| 13 | Wear of Ceramic Nozzles by Dry Sand Blasting显示文摘 | Deng Jianxin Zhang Xihua Niu Pingzhang | 2006 | Tribology International2006，39，3： | 1 |
| 14 | Primary tracheal tumours: 21 years of experience at Peking Union Medical College, Beijing, China显示文摘 | Zhengjaiang L Pingzhang T Dechao Z | 2008 | J Laryngol Otol2008，122，11： | 1 |
| 15 | NetworkevolutionbasedongeneralGpurposedienerubbers/sulfur/TBBSsysGtemduringvulcanization(Ⅰ)显示文摘 | PingZhang FeiZhao YuanYuan | 2010 | Polymer2010，51，1： | 1 |
| 16 | A study on p16 CDK4 and cyclinD1 expression in non-small cell lung cancers显示文摘 | Lingfei K Pingzhang Y Zhengguo L | 1998 | Cancer Lett1998，130，12： | 1 |
| 17 | A study on p16, pRb, CDK4 and CyclinD1 expression in non-small cell lung cancers 显示文摘 | Lingfei K Pingzhang Y Zhengguo L | 1998 | Cancer Lett1998，130，12： | 1 |
| 18 | Cloning of a novel human caspase-9 splice variant containing only the CARD domain显示文摘 | Pingzhang Wang Taiping Shi Dalong Ma | 2006 | Life Sciences2006，，10： | 1 |
| 19 | Management and outcome of cervical lymph node metastases of unknown primary sites: a retrospective study 显示文摘 | Yalin Y Pingzhang T Smith GI | 2002 | Br J Oral Maxillofac Surg2002，40，： | 1 |
| 20 | Primary tracheal tu-mours:21 years of experience at Peking Union Medical college,Beijing,China显示文摘 | Zhengjaiang L Pingzhang T Dechao Z | | 0，，11： | 1 |
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