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| 1 | 2018 Chinese Pediatric Cardiology Society(CPCS) guideline for diagnosis and treatment of syncope in children and adolescents显示文摘Syncope belongs to the transient loss of consciousness(TLOC), characterized by a rapid onset, short duration, and spontaneous complete recovery. It is common in children and adolescents, accounting for 1% to 2% of emergency department visits.Recurrent syncope can seriously affect children's physical and mental health, learning ability and quality of life and sometimes cardiac syncope even poses a risk of sudden death. The present guideline for the diagnosis and treatment of syncope in children and adolescents was developed for guiding a better clinical management of pediatric syncope. Based on the globally recent development and the evidence-based data in China, 2018 Chinese Pediatric Cardiology Society(CPCS) guideline for diagnosis and treatment of syncope in children and adolescents was jointly prepared by the Pediatric Cardiology Society, Chinese Pediatric Society, Chinese Medical Association(CMA)/Committee on Pediatric Syncope, Pediatricians Branch, Chinese Medical Doctor Association(CMDA)/Committee on Pediatric Cardiology, Chinese College of Cardiovascular Physicians, Chinese Medical Doctor Association(CMDA)/Pediatric Cardiology Society, Beijing Pediatric Society, Beijing Medical Association(BMA). The present guideline includes the underlying diseases of syncope in children and adolescents, the diagnostic procedures, methodology and clinical significance of standing test and headup tilt test, the clinical diagnosis vasovagal syncope, postural orthostatic tachycardia syndrome, orthostatic hypotension and orthostatic hypertension, and the treatment of syncope as well as follow-up. | Cheng Wang Yaqi Li Ying Liao Hong Tian Min Huang Xiangyu Dong Lin Shi Jinghui Sun Hongfang Jin Junbao Du Jindou An Jie Chen Mingwu Chen Qi Chen Sun Chen Yonghong Chen Zhi Chen Adolphus Kai-tung Chau Junbao Du Zhongdong Du Junkai Duan Hongyu Duan Xiangyu Dong Lin Feng Lijun Fu Fangqi Gong Yonghao Gui Ling Han Zhenhui Han Bing He Zhixu He Xiufen Hu Yimin Hua Guoying Huang Min Huang Ping Huang Yujuan Huang Hongfang Jin Mei Jin Bo Li Fen Li Tao Li Xiaohui Li Xiaoyan Liu Yan Li Haitao Lv Tiewei Lv Zipu Li Luyi Ma Silin Pan Yusheng Pang Hua Peng Yuming Qin Jie Shen Lin Shi Kun Sun Jinghui Sun Hong Tian Jie Tian Cheng Wang Hong Wang Lei Wang Jinju Wang Wendi Wang Yuli Wang Rongzhou Wu Tianhe Xia Yanyan Xiao Chunhong Xie Yanlin Xing Zhenyu Xiong Baoyuan Xu Yi Xu Hui Yan Shiwei Yang Qijian Yi Xia Yu Xianyi Yu Yue Yuan Hongyan Zhang Huili Zhang Li Zhang Qingyou Zhang Xi Zhang Yanmin Zhang Zhiwei Zhang Cuifen Zhao Bin Zhou Hua Zhu | 2018 | Science Bulletin2018，63，23： | 54 |
| 2 | Enhanced secondary pollution offset reduction of primary emissions during COVID-19 lockdown in China显示文摘To control the spread of the 2019 novel coronavirus(COVID-19),China imposed nationwide restrictions on the movement of its population(lockdown)after the Chinese New Year of 2020,leading to large reductions in economic activities and associated emissions.Despite such large decreases in primary pollution,there were nonetheless several periods of heavy haze pollution in eastern China,raising questions about the well-established relationship between human activities and air quality.Here,using comprehensive measurements and modeling,we show that the haze during the COVID lockdown was driven by enhancements of secondary pollution.In particular,large decreases in NOx emissions from transportation increased ozone and nighttime NO_(3)radical formation,and these increases in atmospheric oxidizing capacity in turn facilitated the formation of secondary particulate matter.Our results,afforded by the tragic natural experiment of the COVID-19 pandemic,indicate that haze mitigation depends upon a coordinated and balanced strategy for controlling multiple pollutants. | Xin Huang Aijun Ding Jian Gao Bo Zheng Derong Zhou Ximeng Qi Rong Tang Jiaping Wang Chuanhua Ren Wei Nie Xuguang Chi Zheng Xu Liangduo Chen Yuanyuan Li Fei Che Nini Pang Haikun Wang Dan Tong Wei Qin Wei Cheng Weijing Liu Qingyan Fu Baoxian Liu Fahe Chai Steven JDavis Qiang Zhang Kebin He | 2021 | National Science Review2021，8，2： | 47 |
| 3 | Hydrogen sulfide ameliorates vascular calcification induced by vitamin D3 plus nicotine in rats显示文摘瞄准:调查内长的胱硫醚 gamma-synthase (CSE ) 的角色在脉管的石灰化的 /hydrogen 硫化物(H2S ) 小径在活体内。方法:脉管的石灰化建模的一只老鼠被维生素 D3 正烟碱(VDN ) 的管理建立。CSE 和 osteopontin (OPN ) 的数量 mRNA 被使用半量的反向抄写的聚合酶链反应决定。钙内容, 45Ca2+ 累积和硷性磷酸酯酶(高山) 活动被测量。H2S 生产和 CSE 活动被测量。结果:染色的 von Kossa 生产了在钙化的主动脉在中间的层的弹性纤维之中在区域染色的强壮的积极黑 / 棕色。分别地,在钙化的动脉的钙内容, 45Ca2+ 累积和高山活动与控制相比由 6.77- , 1.42- ,和 1.87 褶层增加了。OPN 基因的表示起来调整(P<0.01 ) 。基因低是的 CSE 的表示调整了。然而,在 VDN 正 NaHS 的钙内容, 45Ca2+ 举起和高山活动组织在 VDN 组是比那低的。钙和45Ca2+累积和在主动脉的高山的活动的内容是34.8%,40.75%和63.5%比在 VDN 组在低剂量的 NaHS 组降低,分别地( P<0.01 ),并且45Ca2+的钙内容和高山的活动是83.9%, 37.8 %并且46.2%比在 VDN 组在高剂量的 NaHS 组在主动脉降低,分别地( P<0.01 )。基因低是的 OPN 的表示调整了。结论:H2S 的生产,和 CSE 活动被减少, CSE 基因表示低与脉管的石灰化在老鼠调整了。H2S 能改善脉管的石灰化,建议 H2S/CSE 小径在脉管的石灰化的致病起一个规章的作用。 | Sheng-ying WU Chun-shui PAN Bin GENG Jing ZHAO Fang YU Yong-zheng PANG Chao-shu TANG Yong-fen QI | 2006 | Acta Pharmacologica Sinica2006，27，3： | 29 |
| 4 | Pneumoconiosis: current status and future prospects显示文摘Pneumoconiosis refers to a spectrum of pulmonary diseases caused by inhalation of mineral dust,usually as the result of certain occupations.The main pathological features include chronic pulmonary inflammation and progressive pulmonary fibrosis,which can eventually lead to death caused by respiratory and/or heart failure.Pneumoconiosis is widespread globally,seriously threatening global public health.Its high incidence and mortality lie in improper occupational protection,and in the lack of early diagnostic methods and effective treatments.This article reviews the epidemiology,safeguard procedures,diagnosis,and treatment of pneumoconiosis,and summarizes recent research advances and future research prospects. | Xian-Mei Qi Ya Luo Mei-Yue Song Ying Liu Ting Shu Ying Liu Jun-Ling Pang Jing Wang Chen Wang | 2021 | Chinese Medical Journal2021，，8： | 22 |
| 5 | Geothermal data analysis at the high-temperature hydrothermal area in Western Sichuan显示文摘The western Sichuan hydrothermal area is located at the northeastern margin of the eastern syntaxis of the Qinghai-Tibet Plateau, which is also the eastern end of the Mediterranean-Himalayan geothermal activity zone. There are 248 warm or hot springs in this area, and 11 have temperatures beyond the local boiling temperature. Most of these hot springs are distributed along the Jinshajiang, Dege-Xiangcheng, Ganzi-Litang, and Xianshuihe faults, forming a NW-SE hydrothermal belt. A geothermal analysis of this high-temperature hydrothermal area is an important basis for understanding the deep geodynamic process of the eastern syntaxis of the Qinghai-Tibet Plateau. In addition, this study offers an a priori view to utilize geothermal resources, which is important in both scientific research and application. We use gravity, magnetic, seismic, and helium isotope data to analyze the crust-mantle heat flow ratio and deep geothermal structure. The results show that the background terrestrial heat flow descends from southwest to northeast. The crustal heat ratio is not more than 60%. The high temperature hydrothermal active is related to crustal dynamics processes. Along the Batang-Litang-Kangding line, the Moho depth increases eastward, which is consistent with the changing Qc/Qm(crustal/mantle heat flow) ratio trend. The geoid in the hydrothermal zone is 4–6 km higher than the surroundings, forming a local 'platform'. The NW-SE striking local tensile stress zone and uplift structure in the upper and middle crust corresponds with the surface hydrothermal active zone. There is an average Curie Point Depth(CPD) of 19.5–22.5 km in Batang, Litang, and Kangding. The local shear-wave(S-wave) velocity is relatively low in the middle and lower crust. The S-wave shows a low velocity trap(Vs<3.2 km s.1) at 15–30 km, which is considered a high-temperature partial melting magma, the crustal source of the hydrothermal active zone. We conclude that the hydrothermal system in this area can be divided into Batang-type and Kangding-type, both of which rely on a crustal heating cycle of atmospheric precipitation and surface water along the fracture zone. The heat is derived from the middle and lower crust: groundwater penetrates the deep faults bringing geothermal energy back to the surface and forming high-temperature springs. | ZHANG Jian LI WuYang TANG XianChun TIAN Jiao WANG YingChun GUO Qi PANG ZhongHe | 2017 | Science China Earth Sciences2017，60，8： | 17 |
| 6 | Synthesis of new tetrazene(N-N=N-N)-linked bi(1,2,4-triazole)显示文摘The reaction of 4-amino-1,2,4-triazole with sodium dichloroisocyanurate (SDCI) afforded new tetrazene(N-N=N-N)-linked bi(1.2,4-triazole) 2a in excellent yield.Increasing the molar ratio of SDCI to 4-amino-1,2,4-triazole,the chlorinated product 1,5,5′- trichloro-4,4′-azo-1,2,4-triazole (2b) was formed.These new compounds have been characterized by MS,~1H NMR,^(13)C NMR,and elemental analysis. | Sheng Hua Li Si Ping Pang Xiao Tong Li Yong Zhong Yu Xin Qi Zhao | 2007 | Chinese Chemical Letters2007，18，10： | 14 |
| 7 | Myofibroblastic sarcomas:a clinicopathological study of 20 cases显示文摘背景 Myofibroblastic 肉瘤是是一个争论的瘤。这研究调查了 myofibroblastic 肉瘤在不同 locations.Methods 产生的 20 个案例的 clinicopathological 特征从有 myofibroblastic 肉瘤的病人的 20 个案例的嵌入石蜡的织物样品 immunohistochemically 被染色,并且 5 个案例由电子显微镜学检验了。学生的 t 测试被用来分析组织学地把在等级 1 和等级 2 myofibroblastic sarcomas.Results 之间的索引标记的 Ki-67 的差别,肿瘤是有嗜曙红的细胞质的苗条锭子房间镇静、纺锤形、尖端细、起浪,或丰满卵形;小囊的原子核和小中央嗜曙红的 nucleoli。Immunohistochemically,表示的肿瘤房间弄平肌肉肌动朊(18/20 ) ,肌肉特定的肌动朊(16/20 ) , fibronectin (20/20 ) 和 desmin (2/20 ).Ultrastructurally,肿瘤房间表明丰富的不平的 endoplasmic 蜂窝胃和纵在细胞质与焦点的密度安排了好细丝。19 个病人的临床的后续证明 2 个案例经历了本地复发和远转移 6 个月到在起始的手术以后的 4 年。九个盒子局部地复发了在起始的切除以后的 17 ~ 46 个月,和 9 个盒子没有肉瘤,展出多样的组织学的外观,能容易作为良性的肿瘤被误诊的 disease.Conclusions Myofibroblastic 的证据是活着的。Myofibroblastic 肉瘤是有经常的复发的本地破坏损害,并且可以转移远地。 | MENG Guo-zhao ZHANG Hong-ying BU Hong ZHANG Xian-liang PANG Zong-guo KE Qi LIU Xi YANG Guo | 2007 | Chinese Medical Journal2007，，5： | 11 |
| 8 | Evolution on qualities of leachate and landfill gas in the semi-aerobic landfill显示文摘在半氧气的垃圾堆学习稳定的特征,大规模模仿的垃圾堆基于半被构造氧气的垃圾堆理论。因而,化学的氧需求(货到付款) 的集中,氨氮,和亚硝酸根氮,和 pH 在沥滤吃,以及在垃圾堆的垃圾堆气体作文(甲烷,二氧化碳,和氧) 的成分含量定期被监视 52 个星期。结果证明货到付款和氨集中很快衰退了并且没显示出象厌氧的垃圾堆一样的积累的规则,并且分别地,在 48 个星期以后在大约 300 和 100 mg/L 留下。同时,下降的率分别地到达了 98.9% 和 96.9% 。硝酸盐集中在 24 个星期以后很快增加了并且在 43 个星期以后在 220 280 mg/L 之间波动。pH 在开始的 8 个星期期间并且在以后低于 7 沥滤 ates 看起来碱。二氧化碳是在通过整个稳定过程在高水平仍然是的垃圾堆气体和它的集中的主要作文。二氧化碳,氧,和甲烷的平均内容在 19 vol.% 之间改变了 28 vol.% , 2 vol.% 8 vol.% ,和 5 vol.% 13 vol.% 分别地。相对平衡在 48 个星期以后被到达。在垃圾堆房间的最高的温度能等于摄氏的 75.8 度。 | HUANG Qifei YANG Yufei PANG Xiangrui WANG Qi | 2008 | Journal of Environmental Sciences2008，20，4： | 11 |
| 9 | Rapid genomic changes in polyploid wheat and related species:implications for genome evolution and genetic improvement显示文摘A polyploid organism by possessing more than two sets of chromosomes from one species (autopolyploidy) or two or more species (allopolyploidy) is known to have evolutionary advantages. However, by what means a polyploid accommodates increased genetic dosage or divergent genomes (allopolyploidy) in one cell nucleus and cytoplasm constitutes an enormous challenge. Recent years have witnessed efforts and progress in exploring the possible mechanisms by which these seemingly intangible hurdles of polyploidy may be ameliorated or eventually overcome. In particular, the documentation of rapid and extensive non-Mendelian genetic and epigenetic changes that often accompany nascent polyploidy is revealing: the resulting non-additive and novel gene expression at global, regional and local levels, and timely restoration of meiotic chromosomal behavior towards bivalent pairing and disomic inheritance may ensure rapid establishment and stabilization as well as its long-term evolutionary success. Further elucidation on these novel mechanisms underpinning polyploidy will promote our understanding on fundamental issues in evolutionary biology and in our manipulation capacities in future genetic improvement of important crops that are currently polyploids in genomic constitution. This review is intended to provide an updated discussion on these interesting and important issues within the scope of a specific yet one of the most important plant groups-polyploid wheat and its related species. | Bao Liu Chunming Xu Na Zhao Bao Qi Josphert N. Kimatu Jinsong Pang Fangpu Han | 2009 | Journal of Genetics and Genomics2009，36，9： | 10 |
| 10 | Predictive Values of Postoperative and Dynamic Changes of Inflammation Indexes in Survival of Patients with Resected Colorectal Cancer显示文摘The aim of the present study was to evaluate the prognostic potential of postoperative scores of inflammation indexes and the dynamic changes of scores before and after tumor resection in colorectal cancer patients.The study included 516 colorectal cancer patients with primary colorectal tumor resection.Cox regression was applied to estimate the associations of postoperative and dynamic changes of inflammation indexes with progression-free survival and overall survival.As results,we found that higher postoperative neutrophil to lymphocyte ratio (NLR),neutrophil and monocyte to lymphocyte ratio (NMLR),platelet to lymphocyte ratio (PLR) and systemic immune inflammation index (SII)were associated with shorter progression-free survival.The increased NLR,NMLR,PLR,SII and C-reaction protein (CRP)to albumin (ALB) ratio (CAR)were associated with poor progression-free survival,with HRs (95% CIs)of 1.92 (1.27-2.90),1.46(1.11-2.09),2.10(1.34-3.30),1.81(1.22-2.70)and 1.65(1.03-2.67), respectively.Postoperative NMLR,SII,CAR,and their dynamic changes were also significantly correlated with overall survival,with the HRs (95% CIs)of 2.63(1.30-3.97), 2.44(1.43-4.17),2.74(1.31-5.74),2.08(1.21-3.60),1.97(1.12-3.45)and 2.55(1.21-5.38)respectively.In conclusion,postoperative inflammation indexes and their dynamic changes,particularly for NMLR,SII and CAR are promising prognostic predictors of CRC patients. | Zi-quan ZHOU Shuo PANG Xing-chen YU Qi XUE Hong-yu JIANG Xin-jun LIANG Li LIU | 2018 | Current Medical Science2018，38，5： | 10 |
| 11 | Cardioprotective effects of ghrelin and des-octanoyl ghrelin on myocardial injury induced by isoproterenol in rats显示文摘<正> Aim:To determine the cardioprotective action of ghrelin and des-octanoyl ghrelinin rats with isoproterenol-induced myocardial injury.Methods:Rats were subcu-taneously injected with isoproterenol (ISO;20,10,and 5 mg/kg) on d 1,2 and 3,respectively,and then 3 mg/kg for the next 7d with or without ghrelin or des-octanoyl-ghrelin (100μg/kg,twice daily).Plasma ghrelin and growth hormonelevels were assayed using radioimmunoassay methods.Growth hormone secreta-gogue receptor (GHSR) and ghrelin mRNA were determined using RT-PCR.Themaximal binding capacity and the affinity for [~3H]ghrelin were determined by re-ceptor binding assays.Results:Compared with controls,ISO-treated rats showedsevere myocardial injury,cardiomegaly,infarction-like necrosis and massive fi-brosis with increases in irradiated-ghrelin (ir-ghrelin) content in plasma by 67%and myocardia by 66% and in the mRNA level in the myocardia by 93% (P<0.01).ISO-treated rats had 95% (P<0.01) higher GHSR mRNA levels in the myocardia.The maximal binding capacity of [~3H]ghrelin for myocardial sarcolemma was higherin ISO-treated rats than in controls.Ghrelin administration improved cardiac func-tion and ameliorated cardiomegaly and attenuated myocardial lipid peroxidationinjury and relieved cardiac fibrosis as compared with ISO treatment alone.Admin-istration of des-octanoyl ghrelin effectively antagonized ISO-induced myocardialinjury and improved all parameters measured.However,the therapeutic effect ofdes-octanoyl ghrelin was significantly weaker than that of ghrelin.The plasmagrowth hormone level increased markedly,by 1.5-fold (P<0.01),with ghrelinadministration as compared with that in controls,but was unaltered in the des-octanoyl ghrelin group.Conclusion:Myocardial ghrelin and GHSR were up-regulated during ISO-induced myocardial injury.The protective effect of ghrelinagainst ISO-induced cardiac function injury and fibrosis was more potent thanthat of des-octanoyl ghrelin,which suggests that ghrelin could be an endog-enous cardioprotective factor in ischemic heart disease,and that its effects in-clude growth hormone-dependent and-independent pathways. | Lian LI Li-ke ZHANG Yong-zheng PANG Chun-shui PAN Yong-fen QI Li CHEN Xian WANG Chao-shu TANG Jing ZHANG | 2006 | Acta Pharmacologica Sinica2006，27，5： | 9 |
| 12 | Temporal and spatial distribution characteristics of water resources in Guangdong Province based on a cloud model显示文摘With a focus on the difficulty of quantitatively describing the degree of nonuniformity of temporal and spatial distributions of water resources, quantitative research was carried out on the temporal and spatial distribution characteristics of water resources in Guangdong Province from 1956 to 2000 based on a cloud model. The spatial variation of the temporal distribution characteristics and the temporal variation of the spatial distribution characteristics were both analyzed. In addition, the relationships between the numerical characteristics of the cloud model of temporal and spatial distributions of water resources and precipitation were also studied. The results show that, using a cloud model, it is possible to intuitively describe the temporal and spatial distribution characteristics of water resources in cloud images. Water resources in Guangdong Province and their temporal and spatial distribution characteristics are differentiated by their geographic locations. Downstream and coastal areas have a larger amount of water resources with greater uniformity and stronger stability in terms of temporal distribution. Regions with more precipitation possess larger amounts of water resources, and years with more precipitation show greater nonuniformity in the spatial distribution of water resources. The correlation between the nonuniformity of the temporal distribution and local precipitation is small, and no correlation is found between the stability of the nonuniformity of the temporal and spatial distributions of water resources and precipitation. The amount of water resources in Guangdong Province shows an increasing trend from 1956 to 2000, the nonuniformity of the spatial distribution of water resources declines, and the stability of the nonuniformity of the spatial distribution of water resources is enhanced. | Qi Zhou Wei Wang Yong Pang Zhi-yong Zhou Hui-ping Luo | 2015 | Water Science and Engineering2015，8，4： | 9 |
| 13 | Clinical and genetic findings in a Chinese family with VDR-associated hereditary vitamin D-resistant rickets显示文摘Hereditary vitamin D-resistant rickets(HVDRR) is a rare autosomal recessive disorder characterized by severe rickets,hypocalcemia,hypophosphatemia,secondary hyperparathyroidism,and elevated alkaline phosphatase.This disorder is caused by homogeneous or heterogeneous mutations affecting the function of the vitamin D receptor(VDR),which lead to complete or partial target organ resistance to the action of 1,25-dihydroxy vitamin D.A non-consanguineous family of Chinese Han origin with one affected individual demonstrating HVDRR was recruited,with the proband evaluated clinically,biochemically and radiographically.To identify the presence of mutations in the VDR gene,all the exons and exon–intron junctions of the VDR gene from all family members were amplified using PCR and sequenced.The proband showed rickets,progressive alopecia,hypocalcemia,hypophosphatemia,secondary hyperparathyroidism,and elevated alkaline phosphatase.She also suffered from epilepsy,which is rarely seen in patients with HVDRR.Direct sequencing analysis revealed a homozygous missense mutation c.122G4A(p.C41Y) in the VDR gene of the proband,which is located in the first zinc finger of the DNA-binding domain.Both parents had a normal phenotype and were found to be heterozygous for this mutation.We report a Chinese Han family with one individual affected with HVDRR.A homozygous missense mutation c.122G4A(p.C41Y) in the VDR gene was found to be responsible for the patient's syndrome.In contrast to the results of treatment of HVDRR in other patients,our patient responded well to a supplement of oral calcium and a low dose of calcitriol. | Qianqian Pang Xuan Qi Yan Jiang Ou Wang Mei Li Xiaoping Xing Jin Dong Weibo Xia | 2016 | Bone Research2016，4，1： | 9 |
| 14 | A critical review on the application of biochar in environmental pollution remediation:Role of persistent free radicals(PFRs)显示文摘Biochar as an emerging carbonaceous material has exhibited a great potential in environmental application for its perfect adsorption ability.However,there are abundant persistent free radicals(PFRs)in biochar,so the direct and indirect PFRs-mediated removal of organic and inorganic contaminants by biochar was widely reported.In order to comprehend deeply the formation of PFRs in biochar and their interactions with contaminants,this paper reviews the formation mechanisms of PFRs in biochar and the PFRs-mediated environmental applications of biochar in recent years.Finally,future challenges in this field are also proposed.This review provides a more comprehensive understanding on the emerging applications of biochar from the viewpoint of the catalytic role of PFRs. | Kun Luo Ya Pang Dongbo Wang Xue Li Liping Wang Min Lei Qi Huang Qi Yang | 2021 | Journal of Environmental Sciences2021，33，10： | 8 |
| 15 | Hypoxic preconditioning reduces NLRP3 inflammasome expression and protects against cerebral ischemia/reperfusion injury显示文摘Hypoxic preconditioning can protect against cerebral ischemia/reperfusion injury. However, the underlying mechanisms that mediate this effect are not completely clear. In this study, mice were pretreated with continuous, intermittent hypoxic preconditioning;1 hour later, cerebral ischemia/reperfusion models were generated by middle cerebral artery occlusion and reperfusion. Compared with control mice, mice with cerebral ischemia/reperfusion injury showed increased Bederson neurological function scores, significantly increased cerebral infarction volume, obvious pathological damage to the hippocampus, significantly increased apoptosis;upregulated interleukin-1β, interleukin-6, and interleukin-8 levels in brain tissue;and increased expression levels of NOD-like receptor family pyrin domain containing 3(NLRP3), NLRP inflammasome-related protein caspase-1, and gasdermin D. However, hypoxic preconditioning significantly inhibited the above phenomena. Taken together, these data suggest that hypoxic preconditioning mitigates cerebral ischemia/reperfusion injury in mice by reducing NLRP3 inflammasome expression. This study was approved by the Medical Ethics Committee of the Fourth Hospital of Baotou, China(approval No. DWLL2019001) in November 2019. | Yi-Qiang Pang Jing Yang Chun-Mei Jia Rui Zhang Qi Pang | 2022 | Neural Regeneration Research2022，17，2： | 7 |
| 16 | Evaluation of a new method for placing nasojejunal feeding tubes显示文摘AIM:To compare fluoroscopic, endoscopic and guide wire assistance with ultraslim gastroscopy for placement of nasojejunal feeding tubes. METHODS:The information regarding nasojejunal tube placement procedures was retrieved using the gastrointestinal tract database at Tongji Hospital affiliated to Tongji Medical College. Records from 81 patients who underwent nasojejunal tubes placement by different techniques between 2004 and 2011 were reviewed for procedure success and tube-related outcomes. RESULTS:Nasojejunal feeding tubes were successfully placed in 78 (96.3%) of 81 patients. The success rate by fluoroscopy was 92% (23 of 25), by endoscopic technique 96.3% (26 of 27), and by guide wire assistance (whether via transnasal or transoral insertion)100% (23/23, 6/6). The average time for successful placement was 14.9 ± 2.9 min for fluoroscopic placement, 14.8 ± 4.9 min for endoscopic placement, 11.1 ± 2.2 min for guide wire assistance with transnasal gastroscopic placement, and 14.7 ± 1.2 min for transoral gastroscopic placement. Statistically, the duration for the third method was significantly different (P < 0.05) compared with the other three methods. Transnasal placement over a guidewire was significantly faster (P < 0.05) than any of the other approaches. CONCLUSION:Guide wire assistance with transnasal insertion of nasojejunal feeding tubes represents a safe, quick and effective method for providing enteral nutrition. | Hua Qin Xiao-Yun Lu Qiu Zhao De-Min Li Pei-Yuan Li Mei Liu Qi Zhou Liang Zhu Hui-Fang Pang Hui-Zhen Zhao | 2012 | World Journal of Gastroenterology2012，18，37： | 6 |
| 17 | Petrology and geochemistry at the Lower zone-Middle zone transition of the Panzhihua intrusion,SW China:Implications for differentiation and oxide ore genesis显示文摘显示出各向同性、分层、有细密纹理的质地的斑粝岩的一个序列在 260 妈 Panzhihua 侵入的南部的尖端在 Nalaqing 矿被暴露, SW 中国。岩石的域关系,结构,质地和矿物学显示顺序代表在更低的地区和侵入的中间的地区之间的转变。更低的地区特征的各向同性的斑粝岩通过 5 m 厚的 microgabbro 表向上过去到中间的地区的分层的斑粝岩,在以内并且近到哪个 small-scaled,一致 Fe-Ti 氧化物矿石地平线被识别。在在样品的一个子集的 HFSE 和 REE 之间的强壮的分别被归功于到 HFSE 优先地在 REE 上被合并到,在在 Nb/La 之间的平行关系思考了的积云 titanomagnetite Hf/Sm 和 Ti/Ti * 。两个都,各向同性、分层的斑粝岩显示堆积质地并且有类似的矿物质作文(clinopyroxene = 的 Mg# 7679 并且 An5961 ) ,同位素的作文[(87Sr/86Sr ) i = 0.70440.7045 并且 Nd (t)=+2.4 到 +3.9 ] 并且套住的液体内容从 Zr 推断了丰富(1734 ppm ) 。然而,在元素的丰富(V, Cr 和 PGE ) 和在斑粝岩的二种类型之间的比率(Ti/V, La/Yb, Ba/Y 和 Cu/Pd ) 有实质的变化,不能被解释由的特征在一个封闭系统从普通岩浆堆积形成。microgabbros 通常在主要元素作文类似于 high-Ti Emeishan 暗岩,但是他们的低踪迹元素丰富显示一些剩余液体输了尽管有快速的成核,是不可避免的并且冷却。与可得到的数据和观察结合了,我们建议在原处包含结晶化的一个模型,由岩浆列在后面再装并且在 Nalaqing 解释 texturally 特殊的斑粝岩的形成的靠近系统的分别和 Panzhihua 侵入的更低的部分的进化。 | Kwan-Nang Pang Mei-Fu Zhou Liang Qi Sun-Lin Chung Chiu-Hong Chu Hao-Yang Lee | 2013 | Geoscience Frontiers2013，4，5： | 6 |
| 18 | Meso–Cenozoic Tectono-Thermal Evolution History in Bohai Bay Basin, North China显示文摘The thermal history of sedimentary basins is a key factor for hydrocarbon accumulation and resource assessment, and is critical in the exploration of lithospheric tectono-thermal evolution. In this paper, the Cenozoic thermal histories of nearly 200 wells and the Mesozoic thermal histories of 15 wells are modeled based on the vitrinite reflectance and apatite fission track data in Bohai Bay Basin, North China. The results show that the basin experienced Early Cretaceous and Paleogene heat flow peaks, which reveals two strong rift tectonic movements that occurred in the Cretaceous and the Paleogene in the basin, respectively. The thermal evolution history in Bohai Bay Basin can be divided into five stages including(1) the low and stable heat flow stage from the Triassic to the Jurassic, with the heat flow of 53 to 58 m W/m2;(2) the first heat flow peak from the Early Cretaceous to the middle of the Late Cretaceous, with a maximum heat flow of 81 to 87 m W/m2;(3) the first post-rift thermal subsidence stage from the middle of the Late Cretaceous to the Paleocene, with the heat flow of 65 to 74 m W/m2 at the end of the Cretaceous;(4) the second heat flow peak from the Eocene to the Oligocene, with a maximum heat flow of 81 to 88 m W/m2; and(5) the second thermal subsidence stage from the Neogene to present, with an average heat flow of 64 m W/m2. | Yinhui Zuo Nansheng Qiu Jiawei Li Qingqing Hao Xiongqi Pang Zhongying Zhao Qi Zhu | 2015 | Journal of Earth Science2015，26，3： | 6 |
| 19 | Spatiotemporal visualization for the global COVID-19 surveillance by balloon chart显示文摘Background:Considering the widespread of coronavirus disease 2019(COVID-19)pandemic in the world,it is important to understand the spatiotemporal development of the pandemic.In this study,we aimed to visualize time-associated alterations of COVID-19 in the context of continents and countries. | Ming-Fan Pang Zuo-Ru Liang Zhi-Da Cheng Xin-Ping Yang Jie-Wen Wu Ke Lyu Jing-Jing Xi Zhong-Jie Li Guo-Qing Shi Yan-Ping Zhang George FGao Xiao-Peng Qi Xiao-Ping Dong | 2021 | Infectious Diseases of Poverty2021，10，2： | 6 |
| 20 | New Record of Palaeoscolecids from the Early Cambrian of Yunnan,China显示文摘摘要:新 palaeoscolecid, Guanduscolex 次要的胡,罗 et Fu 情报。et sp。nov,与内向的人和肠的保存软部分来自云南的更低的寒武纪的 Guanshan 动物志,华南。扫描电子显微镜学(SEM ) 揭示的表皮的微结构细节证明每个环忍受三排盘子,每个盘子忍受 910 边缘并且 45 个中央节点。这发现在关系和 palaeoscolecids 和另外的早 priapulids 的进化小径上打开新灯。 | HU Shixue LI Yong LUO Huilin FU Xiaoping YOU Ting PANG Jiyuan LIU Qi Michael STEINER | 2008 | Acta Geologica Sinica(English Edition)2008，82，2： | 6 |
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