|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Numerical investigation on flow nonuniformity-induced hysteresis in scramjet isolator显示文摘Numerical simulation and theoretical analysis were conducted to study the hysteresis inside scramjet isolator during the reciprocating process of back pressure variation.It is revealed that only a regular reflection is theoretically possible for two leading shocks when the inflow Mach number is greater than 2.0,and no hysteresis can occur in the transition between shock reflection types.Nevertheless,wall suction,gas injection,and background waves cause non-uniformity of the incoming flow and would make hysteresis possible.Besides the classical hysteresis in the transition between shock reflection,new kinds of hysteresis were found in both the deflection angle of separated boundary layer and the location of the shock train.Moreover,the occurrence of hysteresis in the deflection angle of the separated boundary layer is accompanied with the shock reflection hysteresis.In the case with background waves or gas injection,hysteresis in the starting position of leading shock was observed too.As back pressure decreases,the leading shock does not follow the same path as that as the back pressure increases,and it is anchored at the location where the background shock or the injection interacts with the leading shock.It is inferred that,if two strong adverse pressure gradient regions move towards and interact with each other,hysteresis will take place when they start to separate. | Tinglong HUANG Lianjie YUE Shenghu MA Qifan ZHANG Peng ZHANG Xinyu CHANG | 2020 | Chinese Journal of Aeronautics2020，33，12： | 3 |
| 2 | Carbon nanocages bridged with graphene enable fast kinetics for dual-carbon lithium-ion capacitors显示文摘Lithium-ion capacitors(LICs) combining the advantages of lithium-ion batteries and supercapacitors are considered a promising nextgeneration energy storage device. However, the sluggish kinetics of battery-type anode cannot match the capacitor-type cathode, restricting the development of LICs. Herein, hierarchical carbon framework(HCF) anode material composed of 0D carbon nanocage bridged with 2D graphene network are developed via a template-confined synthesis process. The HCF with nanocage structure reduces the Li^(+) transport path and benefits the rapid Li^(+) migration, while 2D graphene network can promote the electron interconnecting of carbon nanocages. In addition, the doped N atoms in HCF facilitate to the adsorption of ions and enhance the pseudo contribution, thus accelerate the kinetics of the anode. The HCF anode delivers high specific capacity, remarkable rate capability. The LIC pouch-cell based on HCF anode and active HCF(a-HCF) cathode can provide a high energy density of 162 Wh kg^(-1) and a superior power density of 15.8 kW kg^(-1), as well as a long cycling life exceeding 15,000cycles. This study demonstrates that the well-defined design of hierarchical carbon framework by incorporating 0D carbon nanocages and 2D graphene network is an effective strategy to promote LIC anode kinetics and hence boost the LIC electrochemical performance. | Shani Li Yanan Xu Wenhao Liu Xudong Zhang Yibo Ma Qifan Peng Xiong Zhang Xianzhong Sun Kai Wang Yanwei Ma | 2024 | Green Energy & Environment2024，9，3： | 0 |
| 3 | NSP16 promotes the expression of TMPRSS2 to enhance SARS-CoV-2 cell entry显示文摘Since the end of 2019,COVID-19 has caused worldwide pandemic.SARS-CoV-2,the culprit of this epidemic,binds to the host receptor Angiotensin converting enzyme 2(ACE2)using spike(S)protein for cell entry.Recent studies showed that ACE2 expressed at a low level in the main target organs such as lung and bronchial tissues.How SARS-CoV-2 efficiently invades into the respiratory system or other organs with low levels of ACE2 is an urgent problem to be solved. | Tianyu Han Jiapeng Lei Yang Liu Yanan Wang Wenze Xun Qifan Hu Qi Peng Wei Zhang | 2023 | Genes & Diseases2023，10，3： | 0 |
| 4 | Nonalcoholic steatohepatitis critically rewires the ischemia/ reperfusion-induced dysregulation of cardiolipins and sphingolipids in mice显示文摘Background:Lipid dysregulation plays a fundamental role in nonalcoholic steatohepatitis(NASH),which is an emerging critical risk factor that aggravates hepatic ischemia/reperfusion(I/R)injury.However,the specific lipids that mediate the aggressive I/R injury in NASH livers have not yet been identified.Methods:The mouse model of hepatic I/R injury on NASH was established on C56B/6J mice by first feeding the mice with a Western-style diet to induce NASH,then the NASH mice were subjected to surgical procedures to induce hepatic I/R injury.Untargeted lipidomics were performed to determine hepatic lipids in NASH livers with I/R injury through ultra-high performance liquid chromatography coupled with mass spectrometry.The pathology associated with the dysregulated lipids was examined.Results:Lipidomics analyses identified cardiolipins(CL)and sphingolipids(SL),including ceramides(CER),glycosphingolipids,sphingosines,and sphingomyelins,as the most relevant lipid classes that characterized the lipid dysregulation in NASH livers with I/R injury.CER were increased in normal livers with I/R injury,and the I/R-induced increase of CER was further augmented in NASH livers.Metabolic pathway analysis revealed that the enzymes involved in the synthesis and degradation of CER were highly upregulated in NASH livers with I/R injury,including serine palmitoyltransferase 3(Sptlc3),ceramide synthase 2(Cers2),neutral sphingomyelinase 2(Smpd3),and glucosylceramidase beta 2(Gba2)that produced CER,and alkaline ceramidase 2(Acer2),alkaline ceramidase 3(Acer3),sphingosine kinase 1(Sphk1),sphingosine-1-phosphate lyase(Sgpl1),and sphingosine-1-phosphate phosphatase 1(Sgpp1)that catalyzed the degradation of CER.CL were not affected by I/R challenge in normal livers,but CL was dramatically reduced in NASH livers with I/R injury.Consistently,metabolic pathway analyses revealed that the enzymes catalyzing the generation of CL were downregulated in NASH-I/R injury,including cardiolipin synthase(Crls1)and tafazzin(Taz).Notably,the I/R-induced oxidative stress and cell death were found to be aggravated in NASH livers,which were possibly mediated by the reduction of CL and accumulation of CER.Conclusions:The I/R-induced dysregulation of CL and SL were critically rewired by NASH,which might potentially mediate the aggressive I/R injury in NASH livers. | Sheng Yu Kai Wang Qingping Li Yiran Wei Yiyi Li Qifan Zhang Pengxiang Huang Hanbiao Liang Hang Sun Hongxian Peng Xixin Huang Cuiting Liu Jie Zhou Jianping Qian Chuanjiang Li | 2023 | Hepatobiliary Surgery and Nutrition2023，12，1： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员