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| 1 | Denitrification characteristics of a marine origin psychrophilic aerobic denitrifying bacterium显示文摘A psychrophilic aerobic denitrifying bacterium,strain S1-1,was isolated from a biological aerated filter conducted for treatment of recirculating water in a marine aquaculture system.Strain S1-1 was preliminarily identified as Psychrobacter sp.based on the analysis of its 16S rRNA gene sequence,which showed 100% sequence similarity to that of Psychrobacter sp.TSBY-70.Strain S1-1 grew well either in high nitrate or high nitrite conditions with a removal of 100% nitrate or 63.50% nitrite,and the total nitrogen removal rates could reach to 46.48% and 31.89%,respectively.The results indicated that nitrate was mainly reduced in its logarithmic growth phase with a very low leve1 accumulation of nitrite,suggesting that the aerobic denitrification process of strain S1-1 occurred mainly in this phase.The GC-MS results showed that N 2 O was formed as the major intermediate during the aerobic denitrifying process of strain S1-1.Finally,factors affecting the growth of strain S1-1 and its aerobic denitrifying ability were also investigated.Results showed that the optimum aerobic denitrification conditions for strain S1-1 were sodium succinate as carbon source,C/N ratio15,salinity 10 g/L NaCl,incubation temperature 20°C and initial pH 6.5. | Haiyan Zheng Ying Liu Guangdong Sun Xiyan Gao Qingling Zhang Zhipei Liu | 2011 | Journal of Environmental Sciences2011，23，11： | 32 |
| 2 | The willow genome and divergent evolution from poplar after the common genome duplication显示文摘 | Xiaogang Dai Quanjun Hu Qingle Cai Kai Feng Ning Ye Gerald A Tuskan Richard Milne Yingnan Chen Zhibing Wan Zefu Wang Wenchun Luo Kun Wang Dongshi Wan Mingxiu Wang Jun Wang Jianquan Liu Tongming Yin | 2014 | Cell Research2014，24，10： | 28 |
| 3 | Facile Synthesis of Porous Carbon Nitride Spheres with Hierarchical Three-Dimensional Mesostructures for CO_(2) Capture显示文摘Porous carbon nitride(CN)spheres with partially crystalline frameworks have been successfully synthesized via a nanocasting approach by using spherical mesoporous cellular silica foams(MCFs)as a hard template,and ethylenediamine and carbon tetrachloride as precursors.The resulting spherical CN materials have uniform diameters of ca.4μm,hierarchical three-dimensional(3-D)mesostructures with small and large mesopores with pore diameters centered at ca.4.0 and 43 nm,respectively,a relatively high BET surface area of~550 m^(2)/g,and a pore volume of 0.90 cm^(3)/g.High-resolution transmission electron microscope(HRTEM)images,wide-angle X-ray diffraction(XRD)patterns,and Raman spectra demonstrate that the porous CN material has a partly graphitized structure.In addition,elemental analyses,X-ray photoelectron spectra(XPS),Fourier transform infrared spectra(FT-IR),and CO_(2) temperature-programmed desorption(CO_(2)-TPD)show that the material has a high nitrogen content(17.8 wt%)with nitrogen-containing groups and abundant basic sites.The hierarchical porous CN spheres have excellent CO_(2) capture properties with a capacity of 2.90 mmol/g at 25℃and 0.97 mmol/g at 75℃,superior to those of the pure carbon materials with analogous mesostructures.This can be mainly attributed to the abundant nitrogen-containing basic groups,hierarchical mesostructure,relatively high BET surface area and stable framework.Furthermore,the presence of a large number of micropores and small mesopores also enhance the CO_(2) capture performance,owing to the capillary condensation effect. | Qiang Li Jianping Yang Dan Feng Zhangxiong Wu Qingling Wu Sung Soo Park Chang-Sik Ha Dongyuan Zhao | 2010 | Nano Research2010，3，9： | 24 |
| 4 | The Expression and Location of Midkine in Gastric Carcinomas of Chinese Patients显示文摘Midkine (MK), a heparin-binding growth factor, can regulate cell growth, survival and differentiation. MK is expressed at high levels in a variety of human carcinomas. Recently, the urine and serum MK concentration was analyzed in gastric cancer patient. However, the association of the cytokine mRNA expression with the categorical clinicopathological variables of the tumors and the location of its protein expression in the tumor tissues are still elusive. MK mRNA expression from the surgically resected specimens of healthy gastric tissues (9 cases), gastric cancer tissues and the matched non-cancerous tissues adjacent to the cancer (37 cases) were assessed by reverse transcriptase-polymerase chain reaction (RT-PCR) and real-time PCR. Immunohistochemical analysis was performed to locate MK in gastric cancer. The expression of MK mRNA in gastric cancer was much higher in tumor tissues than that in the non-cancerous tissues and control tissue samples. And its expression was significantly associated with the pTNM stage and distant metastasis, but not with the differentiation grade, tumor size and nodal involvement. MK protein was ubiquitous in the tumor, especially in the adenoid part of tumors. In addition, it was found in the cytoplasm of tumor cells and highly concentrated in nucleus and nucleolus. The expression level and location of MK in gastric tumor tissues of Chinese Patients may be related to the tumor genesis and progression. Further study is necessary on the mechanism of MK in gastric tumorigenesis and tumor growth. | Yaling Huang Guochun Cao Hui Wang Qingling Wang Yayi Hou | 2007 | Cellular & Molecular Immunology2007，4，2： | 17 |
| 5 | SnCl_4催化合成邻苯二甲酸二丁酯显示文摘邻苯二甲酸二丁酯的传统工业制法是用浓硫酸催化邻苯二甲酸酐和正丁醇进行酯化,但副产物多,而且设备腐蚀严重.近年来随着催化剂的广泛研究,出现固体超强酸SO2-4/ZrO2[1,2]、SO2-4/TiO2[1,3]、氧化物SnO[4]、盐类Fe2(SO4)... | Zeng Qingle (Department of Chemistry,Zhangzhou Normal College,Zhangzhou 363000) | 1999 | 应用化学1999，16，3： | 16 |
| 6 | Traditional Chinese medicine in COVID-19显示文摘COVID-19 pandemic caused by severe acute respiratory syndrome coronavirus 2(SARSCo V-2)has spread across the globe,posing an enormous threat to public health and safety.Traditional Chinese medicine(TCM),in combination with Western medicine(WM),has made important and lasting contributions in the battle against COVID-19.In this review,updated clinical effects and potential mechanisms of TCM,presented in newly recognized three distinct phases of the disease,are summarized and discussed.By integrating the available clinical and preclinical evidence,the efficacies and underlying mechanisms of TCM on COVID-19,including the highly recommended three Chinese patent medicines and three Chinese medicine formulas,are described in a panorama.We hope that this comprehensive review not only provides a reference for health care professionals and the public to recognize the significant contributions of TCM for COVID-19,but also serves as an evidence-based in-depth summary and analysis to facilitate understanding the true scientific value of TCM. | Ming Lyu Guanwei Fan Guangxu Xiao Taiyi Wang Dong Xu Jie Gao Shaoqin Ge Qingling Li Yuling Ma Han Zhang Jigang Wang Yuanlu Cui Junhua Zhang Yan Zhu Boli Zhang | 2021 | Acta Pharmaceutica Sinica B2021，11，11： | 14 |
| 7 | The genesis of tectono-magmatism in eastern China显示文摘The tectono-magmatism in eastern China is a hotspot for the researches, and many hypotheses of that were discussed. There is a middle crust with solid, low velocity and high conductivity in eastern China, which is impossible to form'convection magmatic layer'. The subduction and compression of oceanic plate induced to the lateral pressure for the eastern China lithosphere in the condition of increasing pressure and decreasing temperature, it is also impossible to form an extensively melting magma layer. In South China, the granitic zone migrates from west to east, their evolution cannot be explained by plate subduction. The original magmatic reservoirs are controlled by main faults and spheres, which occurred the tectonic detachment and formed in the process of decreasing pressure and increasing temperature. The magma only originates in very small part of lithosphere. The tectono-magmatism and tectonic detachment of eastern China lithosphere during the Jurassic and the Cretaceous are concentrate mainly near the intersections between the regional faults and middle crust or the Moho discontinuity, and then magma intrudes or erupts along faults. The tectono-magmatism of Cenozoic originates near the intersections between the regional high-angle normal faults and the bottom of lithosphere. Obviously, the different penetration depth of faults induces a different kind of magmatism. | WAN TianFeng ZHAO QingLe | 2012 | Science China Earth Sciences2012，55，3： | 14 |
| 8 | Mechanism of lead immobilization by oxalic acid-activated phosphate rocks显示文摘Lead (Pb) chemical fixation is an important environmental aspect for human health. Phosphate rocks (PRs) were utilized as an adsorbent to remove Pb from aqueous solution. Raw PRs and oxalic acid-activated PRs (APRs) were used to investigate the effect of chemical modification on the Pb-binding capacity in the pH range 2.0-5.0. The Pb adsorption rate of all treatments above pH 3.0 reached 90%. The Pb binding on PRs and APRs was pH-independent, except at pH 2.0 in activated treatments. The X-ray diffraction analysis confirmed that the raw PRs formed cerussite after reacting with the Pb solution, whereas the APRs formed pyromorphite. The Fourier Transform Infrared spectroscopy analysis indicated that carbonate (CO32-) in raw PRs and phosphate (PO43-) groups in APRs played an important role in the Pb-binding process. After adsorption, anomalous block-shaped particles were observed by scanning electron microscopy with energy dispersive spectroscopy. The X-ray photoelectron spectroscopy data further indicated that both chemical and physical reactions occurred during the adsorption process according to the binding energy. Because of lower solubility of pyromorphite compared to cerussite, the APRs are more effective in immobilizing Pb than that of PRs. | Guanjie Jiang Yonghong Liu Li Huang Qingling Fu Youjun Deng Hongqing Hu | 2012 | Journal of Environmental Sciences2012，24，5： | 12 |
| 9 | In situ preparation of g-C3N4/Bi4O5I2 complex and its elevated photoactivity in Methyl Orange degradation under visible light显示文摘A graphite carbon nitride(g-C3N4)modified Bi4O5I2 composite was successfully prepared insitu via the thermal treatment of a g-C3N4/Bi OI precursor at 400°C for 3 hr.The as-prepared g-C3N4/Bi4O5I2 showed high photocatalytic performance in Methyl Orange(MO)degradation under visible light.The best sample presented a degradation rate of 0.164 min^-1,which is 3.2 and 82 times as high as that of Bi4O5I2 and g-C3N4,respectively.The g-C3N4/Bi4O5I2 was characterized by X-ray powder diffractometer(XRD),scanning electron microscopy(SEM),transmission electron microscopy(TEM),Raman,X-ray photoelectron spectroscopy(XPS),ultraviolet-visible diffuse reflectance spectra(DRS),electrochemical impedance spectroscopy(EIS)and transient photocurrent response in order to explain the enhanced photoactivity.Results indicated that the decoration with a small amount of g-C3N4 influenced the specific surface area only slightly.Nevertheless,the capability for absorbing visible light was improved measurably,which was beneficial to the MO degradation.On top of that,a strong interaction between g-C3N4 and Bi4O5I2 was detected.This interplay promoted the formation of a favorable heterojunction structure and thereby enhanced the charge separation.Thus,the g-C3N4/Bi4O5I2 composite presented greater charge separation efficiency and much better photocatalytic performance than Bi4O5I2.Additionally,g-C3N4/Bi4O5I2 also presented high stability.·O2^- and holes were verified to be the main reactive species. | Zhe Feng Lin Zeng Qingle Zhang Shifeng Ge Xinyue Zhao Hongjun Lin Yiming He | 2020 | Journal of Environmental Sciences2020，32，1： | 12 |
| 10 | Self-triggered Consensus Control for Linear Multi-agent Systems With Input Saturation显示文摘In this paper, we study the consensus problem for a class of linear multi-agent systems(MASs) with consideration of input saturation under the self-triggered mechanism. In the context of discrete-time systems, a self-triggered strategy is developed to determine the time interval between the adjacent triggers. The triggering condition is designed by using the current sampled consensus error. Furthermore, the consensus control protocol is designed by means of a state feedback approach. It is shown that the considered multi-agent systems can reach consensus with the presented algorithm. Some sufficient conditions are proposed in the form of linear matrix inequalities(LMIs) to show the positively invariant property of the domain of attraction(DOA). Moreover, some sufficient conditions of controller synthesis are provided to enlarge the volume of the DOA and obtain the control gain matrix. A numerical example is simulated to demonstrate the effectiveness of the theoretical analysis results. | Yanxu Su Qingling Wang Changyin Sun | 2020 | IEEE/CAA Journal of Automatica Sinica2020，7，1： | 11 |
| 11 | Optimization of clay material mixture ratio and filling process in gypsum mine goaf显示文摘Because there is neither waste rock nor mill tailings in the gypsum mine, and the buildings on the goaf of gypsum mine are needed to be protected, the research proposed the scheme of the clay filling technology. Gypsum, cement, lime and water glass were used as adhesive, and the strength of different material ratios were investigated in this study. The influence factors of clay strength were obtained in the order of cement, gypsum, water glass and lime. The results show that the cement content is the determinant influence factor, and gypsum has positive effects, while the water glass can enhance both clay strength and the fluidity of the filing slurry. Furthermore, combining chaotic optimization method with neural network, the optimal ratio of composite cementing agent was obtained. The results show that the optimal ratio of water glass, cement, lime and clay (in quality) is 1.17:6.74:4.17:87.92 in the process of bottom self-flow filling, while the optimal ratio is 1.78:9.58:4.71:83.93 for roof-contacted filling. A novel filling process to fill in gypsum mine goaf with clay is established. The engineering practice shows that the filling cost is low, thus, notable economic benefit is achieved. | Liu Zhixiang Dang Wengang Liu Qingling Chen Guanghui Peng Kang | 2013 | International Journal of Mining Science and Technology2013，23，3： | 11 |
| 12 | Cancer situation in China:what does the China cancer map indicate fromthe first national death survey to the latest cancer registration?显示文摘Background:Over the past four decades,the Chinese government has conducted three surveys on the distribution of causes of death and built cancer registration.In order to shine a new light on better cancer prevention strategies in China,we evaluated the profile of cancer mortality over the forty years and analyzed the policies that have been implemented.Methods:We described spatial and temporal changes in both cancer mortality and the ranking of major cancer types in China based on the data collected from three national surveys during 1973-1975,1990-1992,2004-2005,and the latest cancer registration data published by National Central Cancer Registry of China.The mortality data were compared after conversion to age-standardized mortality rates based on the world standard population(Segi’s population).The geographical distribution characteristics were explored by marking hot spots of different cancers on the map of China.Results:From 1973 to 2016,China witnessed an evident decrease in mortality rate of stomach,esophageal,and cervical cancer,while a gradual increase was recorded in lung,colorectal,and female breast cancer.A slight decrease of mortality rate has been observed in liver cancer since 2004.Lung and liver cancer,however,have become the top two leading causes of cancer death for the last twenty years.From the three national surveys,similar profiles of leading causes of cancer death were observed among both urban and rural areas.Lowermortality rates from esophageal and stomach cancer,however,have been demonstrated in urban than in rural areas.Rural areas had similar mortality rates of the five leading causes of cancer death with the small urban areas in 1973-1975.Additionally,rural areas in 2016 also had approximate mortality rates of the five leading causes with urban areas in 2004-2005.Moreover,stomach,esophageal,and liver cancer showed specific geographical distributions.Althoughmortality rates have decreased atmost of the hotspots of these cancers,they were still higher than the national average levels during the same time periods.Conclusions:Building up a strong primary public health system especially among rural areas may be one critical step to reduce cancer burden in China. | Ruimei Feng Qingling Su Xiaoyin Huang Til Basnet Xin Xu Weimin Ye | 2023 | Cancer Communications2023，43，1： | 10 |
| 13 | Stability of singular networked control systems with control constraint显示文摘Based on bounded network-induced time-delay, the networked control system is modeled as a linear time-variant singular system. Using the Lyapunov theory and the linear matrix inequality approach, the criteria for delay-independent stability and delay-dependent stability of singular networked control systems are derived and transformed to a feasibility problem of linear matrix inequality formulation, which can be solved by the Matlab LMI toolbox, and the feasible solutions provide the maximum allowable delay bound that makes the system stable. A numerical example is provided, which shows that the analysis method is valid and the stability criteria are feasible. | Qiu Zhanzhi Zhang Qingling Zhao Zhiwu | 2007 | Journal of Systems Engineering and Electronics2007，18，2： | 9 |
| 14 | Recent advances in ionic liquids-based hybrid processes for CO_(2) capture and utilization显示文摘CO_(2) capture and utilization(CCU)is an effective strategy to mitigate global warming.Absorption,adsorption and membranes are methods used for CO_(2) separation and capture,and various catalytic pathways have also been developed for CO_(2) utilization.Although widely researched and used in industry,these processes are energy-intensive and this challenge needs to be overcome.To realize further optimization,novel materials and processes are continuously being developed.New generation materials such as ionic liquids(ILs)have shown promising potential for cost-effective CO_(2) capture and utilization.This study reviews the current status of ILs-based solvents,adsorbents,membranes,catalysts and their hybrid processes for CO_(2) capture and utilization.The special properties of ILs are integrated into new materials through hybridization,which significantly improves the performance in the process of CCU. | Shaohan Lian Chunfeng Song Qingling Liu Erhong Duan Hongwei Ren Yutaka Kitamura | 2021 | Journal of Environmental Sciences2021，33，1： | 9 |
| 15 | Dry/wet climate zoning and delimitation of arid areas of Northwest China based on a data-driven fashion显示文摘The division of arid areas is important in water and land resources management, planning and for a long-term agricultural, economic and social planning. Northwest China(NW) dominates the main arid areas in China. There is thus a need to adopt adequate concepts relative to the scope of arid areas of NW China and identify its climate types and characteristics. In this study, we analyzed climatic data over the last 30 years(1981–2010) from 191 stations in three provinces and three autonomous regions of NW China. The factor-cluster analysis tech- nique(FC), an objective and automated method was employed to classify the dry/wet climate zones. The traditional methods with predefined thresholds were adopted for providing a comparison with FC. The results showed that the wet/dry climate zones by FC were mainly distributed along mountains, rivers and desert borders. Climate-division boundaries relied heavily on the major terrain features surrounding the grouped stations. It also showed that the climate was dry in the plain sandy areas but relatively wet in the high mountain areas. FC method can reflect the climate characteristics more fully in NW China with varied and complicated topography, and outperform the tradi- tional climate classifications. Arid areas of NW China were defined as four climate types, including five resultant classes in FC classifications. The Qinling and Da Hinggan Mountains were two important boundaries, besides main administrative boundaries. The results also indicated that there are some differences between two traditional clas- sifications. The precipitation moved and fluctuated to an extent, which confirmed that climate change played an important role in the dry/wet climate zoning, and the boundaries of dry/wet climate zones might change and migrate with time. This paper is expected to provide a more in-depth understanding on the climate characteristics in arid areas of NW China, and then contribute to formulate reasonable water and land management planning and agri- cultural production programs. | QingLing GENG PuTe WU QingFeng ZHANG XiNing ZHAO YuBao WANG | 2014 | Journal of Arid Land2014，6，3： | 9 |
| 16 | Immobilization of lead in anthropogenic contaminated soils using phosphates with/without oxalic acid显示文摘Understanding the effects of oxalic acid(OA) on the immobilization of Pb(Ⅱ) in contaminated soils by phosphate materials, has considerable benefits for risk assessment and remediation strategies for the soil. A series of phosphate amendments with/without oxalic acid were applied to two anthropogenic contaminated soils. We investigated the immobilization of Pb(Ⅱ) by KH2PO4, phosphate rock(PR), activated phosphate rock(APR) and synthetic hydroxyapatite(HAP) at different phosphate:Pb(P:Pb) molar ratios(0, 0.6, 2.0 and 4.0) in the presence/absence of 50 mmol oxalic acid/kg soil, respectively. The effects of treatments were evaluated using single extraction with deionized water or Ca Cl2, Community Bureau of Reference(BCR) sequential extraction and toxicity characteristic leaching procedure(TCLP)methods. Our results showed that the concentration of water extractable, exchangeable and TCLP-Pb all decreased with incubation time. The concentration of water-extractable Pb after120 days was reduced by 100% when soils were amended with APR, HAP and HAP + OA, and the TCLP-Pb was <5 mg/L for the red soil at P:Pb molar ratio 4.0. Water-soluble Pb could not be detected and the TCLP-Pb was <5 mg/L at all treatments applied to the yellow-brown soil. BCR results indicated that APR was most effective, although a slight enhancement of water-soluble phosphate was detected at the P:Pb molar ratio 4.0 at the beginning of incubation. Oxalic acid activated phosphates, and so mixing insoluble phosphates with oxalic acid may be a useful strategy to improve their effectiveness in reducing Pb bioavailability. | Xiaojuan Su Jun Zhu Qingling Fu Jichao Zuo Yonghong Liu Hongqing Hu | 2015 | Journal of Environmental Sciences2015，27，2： | 9 |
| 17 | A systematic review of research studies on the estimation of net primary productivity in the Three-River Headwater Region, China显示文摘三河的 Headwater 区域(TRHR ) ,作为中国的水塔知道,为在中国和很多个东南亚洲国家的许多下游的区域是为国家安全兴趣和地区性的持续发展活动的一个重要生态的躲蔽处。TRHR 是有一个唯一,却典型的高山的植被系统的高举起的、冷环境。网络主要生产率(NPP ) 是能反映自然环境变化和碳预算层次的一个关键植被参数和生态的指示物。给唯一的地理环境和 TRHR 的战略地点,许多学者由使用不同方法估计了 TRHR 的 NPP;然而,这些估计为很多个原因极大地变化。迄今为止,没有纸,考察了并且估计在 TRHR 进行的 NPP 评价研究。在这篇论文,(1 ) 因此,我们在以前的研究的系统的评论在 TRHR 总结了 NPP 评价的相关方法和结果;(2 ) 为在 TRHR 估计 NPP 讨论了存在方法的适用性并且加亮最重要的挑战;并且(3 ) 估计了估计的 NPP 结果。最后,在 TRHR 的 NPP 评价的发展方向被勘探。 | SUN Qingling LI Baolin ZHOU Chenghu LI Fei ZHANG Zhijun DING Lingling ZHANG Tao XU Lili | 2017 | Journal of Geographical Sciences2017，27，2： | 8 |
| 18 | Allogeneic Vγ9Vδ2 T-cell immunotherapy exhibits promising clinical safety and prolongs the survival of patients with late-stage lung or liver cancer显示文摘Vγ9Vδ2 T cells are promising candidates for cellular tumor immunotherapy.Due to their HLA-independent mode of action,allogeneic Vγ9Vδ2 T cells can be considered for clinical application.To apply allogeneic Vγ9Vδ2 T cells in adoptive immunotherapy,the methodology used to obtain adequate cell numbers with optimal effector function in vitro needs to be optimized,and clinical safety and efficacy also need to be proven.Therefore,we developed a novel formula to improve the expansion of peripheralγδT cells from healthy donors.Then,we used a humanized mouse model to validate the therapeutic efficacy of expandedγδT cells in vivo;furthermore,the expandedγδT cells were adoptively transferred into late-stage liver and lung cancer patients.We found that the expanded cells possessed significantly improved immune effector functions,including proliferation,differentiation,and cancer cell killing,both in vitro and in the humanized mouse model.Furthermore,a phase I clinical trial in 132 late-stage cancer patients with a total of 414 cell infusions unequivocally validated the clinical safety of allogeneic Vγ9Vδ2 T cells.Among these 132 patients,8 liver cancer patients and 10 lung cancer patients who received≥5 cell infusions showed greatly prolonged survival,which preliminarily verified the efficacy of allogeneic Vγ9Vδ2 T-cell therapy.Our clinical studies underscore the safety and efficacy of allogeneic Vγ9Vδ2 T-cell immunotherapy,which will inspire further clinical investigations and eventually benefit cancer patients. | Yan Xu Zheng Xiang Mohammed Alnaggar Léonce Kouakanou Jiawei Li Junyi He Jiashuang Yang Yi Hu Yan Chen Li Lin Jianlei Hao Jingxia Li Jibing Chen Man Li Qingling Wu Christian Peters Qinghua Zhou Jianshuang Li Yingqing Liang Xiaohua Wang Baohui Han Meili Ma Dieter Kabelitz Kecheng Xu Wenwei Tu Yangzhe Wu Zhinan Yin | 2021 | Cellular & Molecular Immunology2021，18，2： | 8 |
| 19 | Comparing the regeneration potential between PLLA/Aragonite and PLLA/ Vaterite pearl composite scaffolds in rabbit radius segmental bone defects显示文摘Mussel-derived nacre and pearl,which are natural composites composed CaCO3 platelets and interplatelet organic matrix,have recently gained interest due to their osteogenic potential.The crystal form of CaCO3 could be either aragonite or vaterite depending on the characteristics of mineralization template within pearls.So far,little attention has been paid on the different osteogenic capacities between aragonite and vaterite pearl.In the current work,aragonite or vaterite pearl powders were incorporated into poly-L-lactic acid(PLLA)scaffold as bio-functional fillers for enhanced osteogenesis.In intro results revealed that PLLA/aragonite scaffold possessed stronger stimulatory effect on SaOS-2 cell proliferation and differentiation,evidenced by the enhanced cell viability,alkaline phosphatase activity,collagen synthesis and gene expressions of osteogenic markers including osteocalcin,osteopotin and bone sialoprotein.The bone regeneration potential of various scaffolds was evaluated in vivo employing a rabbit critical-sized radial bone defect model.The X-ray and micro-CT results showed that significant bone regeneration and bridging were achieved in defects implanted with composite scaffolds,while less bone formation and non-bridging were found for pure PLLA group.Histological evaluation using Masson's trichrome and hematoxylin/eosin(H&E)staining indicated a typical endochondral bone formation process conducted at defect sites treated with composite scaffolds.Through three-point bending test,the limbs implanted with PLLA/aragonite scaffold were found to bear significantly higher bending load compared to other two groups.Together,it is suggested that aragonite pearl has superior osteogenic capacity over vaterite pearl and PLLA/aragonite scaffold can be employed as a potential bone graft for bone regeneration. | Qianli Huang Yuansheng Liu Zhengxiao Ouyang Qingling Feng | 2020 | Bioactive Materials2020，5，4： | 7 |
| 20 | Paleozoic Tectono-Metallogeny in the Tianshan-Altay Region,Central Asia显示文摘The research on Paleozoic tectonics and endogenic metallogeny in the Tianshan-Altay region of Central Asia is an important and significant project. The Altay region, as a collision zone of the Early Paleozoic(500–397 Ma), and the Tianshan region, as a collision zone of the early period in the Late Paleozoic(Late Devonian-Early Carboniferous, 385–323 Ma), are all the result of nearly N-S trending shortening and collision(according to recent magnetic orientation). In the Late Devonian-Early Carboniferous period(385–323 Ma), regional NW trending faults displayed features of dextral strike-slip motion in the Altay and Junggar regions. In the Tianshan region, nearly EW-trending regional faults are motions of the thrusts. However, in the Late Carboniferous-Early Permian period(323–260 Ma), influenced by the long-distance effect induced from the Ural collision zone, those areas suffered weaker eastward compression, the existing NW trending faults converted into sinistral strike-slip in the Altay and Junggar regions, and the existing nearly E-W trending faults transferred into dextral strike-slip faults in the Tianshan region. The Rocks of those regions in the Late Carboniferous-Early Permian period(323–260 Ma) were moderately ruptured to a certain tension-shear, and thus formed a number of world famous giant endogenic metal ore deposits in the Tianshan-Altay region. As to the Central Asian continent, the most powerful collision period may not coincide with the most favorable endogenic metallogenic period. It should be treated to 'the orogenic metallogeny hypothesis' with caution in that region. | WAN Tianfeng ZHAO Qingle WANG Qianqian | 2015 | Acta Geologica Sinica(English Edition)2015，89，4： | 6 |
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