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| 1 | Isolation and initial characterization of GW5, a major QTL associated with rice grain width and weight显示文摘谷物重量是庄稼谷物产量的一个主要决定因素并且被自然地发生的量的特点 loci (QTL ) 控制。我们更早识别了控制米饭谷物宽度和重量的主要 QTL, GW5,它在米饭染色体 5 上被印射到一个再结合热点。获得 GW5 怎么控制米饭谷物宽度的更好的理解,我们进行了这个地点的好印射并且揭开在米饭栽培变种 Asominori 与增加的谷物宽度联系的 1 212-bp 删除,与苗条谷物米饭 IR24 比较。另外, 46 米饭栽培变种的 genotyping 分析表明这删除高度与谷物宽度显型被相关,建议 GW5 删除可能在米饭驯服期间被选择了。GW5 编码对原子核局部性的 144 氨基酸的新奇原子蛋白质。而且,我们证明 GW5 身体上在酵母与 polyubiquitin 交往二混血儿的试金。一起,我们的结果建议 GW5 代表主要 QTL 内在的米饭宽度和重量,并且它多半在 ubiquitin-proteasome 小径行动在种子开发期间调整房间分割。这研究提供新奇卓见进控制米饭谷物开发的分子的机制并且建议 GW5 能为庄稼的产量很高的繁殖用作一个潜在的工具。 | Jianfeng Weng Suhai Gu Xiangyuan Wan He Gao Tao Guo Ning Su Cailin Lei Xin Zhang Zhijun Cheng Xiuping Guo Jiulin Wang Ling Jiang Huqu Zhai Jianmin Wan | 2008 | Cell Research2008，18，12： | 248 |
| 2 | The Tartary Buckwheat Genome Provides Insights into Rutin Biosynthesis and Abiotic Stress Tolerance显示文摘 | Zhang, Lijun Li, Xiuxiu Ma, Bin Gao, Qiang Du, Huilong Han, Yuanhuai Li, Yan Cao, Yinghao Qi, Ming Zhu, Yaxin Lu, Hongwei Ma, Mingchuan Liu, Longlong Zhou, Jianping Nan, Chenghu Qin, Yongjun Wang, Jun Cui, Lin Liu, Huimin Liang, Chengzhi Qiao, Zhijun | 2017 | Molecular Plant2017，10，9： | 53 |
| 3 | Variations between rice cultivars in iron and manganese plaque on roots and the relation with plant cadmium uptake显示文摘To understand certain mechanisms causing variations between rice cultivars with regard to cadmium uptake and tolerance,pot soil experiments were conducted with two rice cultivars of different genotypes under different soil Cd levels.The relationships between plant Cd uptake and iron/manganese(Fe/Mn) plaque formation on roots were investigated.The results showed that rice cultivars di?ered markedly in Cd uptake and tolerance.Under soil Cd treatments,Cd concentrations and accumulations in the cultivar Shanyou 63(the genotype indica) were significantly higher than those in the cultivar Wuyunjing 7(the genotype japonica)(P < 0.01,or P < 0.05),and Shanyou 63 was more sensitive to Cd toxicity than Wuyunjing 7.The differences between the rice cultivars were the largest at relatively low soil Cd level(i.e.,10 mg/kg).Fe concentrations in dithionite-citrate-bicarbonate root extracts of Shanyou 63 were generally lower than that of Wuyunjing 7,and the difference was the most significant under the treatment of 10 mg Cd/kg soil.The results indicated that the formation of iron plaque on rice roots could act as a barrier to soil Cd toxicity,and may be a 'buffer' or a 'reservoir' which could reduce Cd uptake into rice roots.And the plaque may contribute,to some extent,to the genotypic differences of rice cultivars in Cd uptake and tolerance. | Jianguo Liu Changxun Cao Minghung Wong Zhijun Zhang Yuhong Chai | 2010 | Journal of Environmental Sciences2010，22，7： | 43 |
| 4 | Emergence and prevalence of naturally occurring lower virulent African swine fever viruses in domestic pigs in China in 2020显示文摘African swine fever virus(ASFV)has been circulating in China for more than two years,and it is not clear whether the biological properties of the virus have changed.Here,we report on our surveillance of ASFVs in seven provinces of China,from June to December,2020.A total of 22 viruses were isolated and characterized as genotype II ASFVs,with mutations,deletions,insertions,or short-fragment replacement occurring in all isolates compared with Pig/HLJ/2018(HLJ/18),the earliest isolate in China.Eleven isolates had four different types of natural mutations or deletion in the EP402R gene and displayed a nonhemadsorbing(non-HAD)phenotype.Four isolates were tested for virulence in pigs;two were found to be as highly lethal as HLJ/18.However,two non-HAD isolates showed lower virulence but were highly transmissible;infection with 106 TCID50 dose was partially lethal and caused acute or sub-acute disease,whereas 103 TCID50 dose caused non-lethal,sub-acute or chronic disease,and persistent infection.The emergence of lower virulent natural mutants brings greater difficulty to the early diagnosis of ASF and creates new challenges for ASFV control. | Encheng Sun Zhenjiang Zhang Zilong Wang Xijun He Xianfeng Zhang Lulu Wang Wenqing Wang Lianyu Huang Fei Xi Haoyue Huangfu Ghebremedhin Tsegay Hong Huo Jianhong Sun Zhijun Tian Wei Xia Xuewu Yu Fang Li Renqiang Liu Yuntao Guan Dongming Zhao Zhigao Bu | 2021 | Science China(Life Sciences)2021，64，5： | 46 |
| 5 | Contemporary crustal deformation of the Chinese continent and tectonic block model显示文摘We obtain the preliminary result of crustal deformation velocity field for the Chinese con-tinent by analyzing GPS data from the Crustal Motion Observation Network of China (CMONOC), particularly the data from the regional networks of CMONOC observed in 1999 and 2001. We de-lineate 9 tectonically active blocks and 2 broadly distributed deformation zones out of a denseGPS velocity field, and derive block motion Euler poles for the blocks and their relative motionrates. Our result reveals that there are 3 categories of deformation patterns in the Chinese conti-nent. The first category, associated with the interior of the Tibetan Plateau and the Tianshan oro-genic belt, shows broadly distributed deformation within the regions. The third category, associatedwith the Tarim Basin and the region east of the north-south seismic belt of China, shows block-likemotion, with deformation accommodated along the block boundaries only. The second category, mainly associated with the borderland of the Tibetan Plateau, such as the Qaidam, Qilian, Xining(in eastern Qinghai), and the Diamond-shaped (in western Sichuan and Yunnan) blocks, has thedeformation pattern between the first and the third, i.e. these regions appear to deform block-like,but with smaller sizes and less strength for the blocks. Based on the analysis of the lithosphericstructures and the deformation patterns of the regions above, we come to the inference that thedeformation modes of the Chinese continental crust are mainly controlled by the crustal structure.The crust of the eastern China and the Tarim Basin is mechanically strong, and its deformationtakes the form of relative motion between rigid blocks. On the other hand, the northward indentation of the Indian plate into the Asia continent has created the uplift of the Tibetan Plateau and the Tianshan Mountains, thickened their crust, and raised the temperature in the crust. The lower crust thus has become ductile, evidenced in low seismic velocity and high electric conductivity observed. The brittle part of the crust, driven by the visco-plastic flow of the lower crust, deforms extensively at all scales. The regions of the second category located at the borderland of the Tibetan Plateau are at the transition zone between the regions of the first and the third categories in terms of the crustal structure. Driven by the lateral boundary forces, their deformation style is also between the two, in the form of block motion and deformation with smaller blocks and less internal strength. | WANG Min (王 敏) SHEN Zhengkang (沈正康) NIU Zhijun (牛之俊) ZHANG Zusheng (张祖胜) SUN Hanrong (孙汉荣) GAN Weijun (甘卫军) WANG Qi (王 琪) REN Qun (任 群) | 2003 | Science China Earth Sciences2003，46，z2： | 33 |
| 6 | Prognostic value of systemic immune.inflammation index in patients with gastric cancer显示文摘Background:Inflammation-based indexes have been used to predict survival and recurrence in cancer patients.Systemic immune-inflammation index(Sll) was reported to be associated with prognosis in some malignant tumors.In the present study,we aimed to explore the association between Sll and the prognosis of patients with gastric cancer.Methods:We retrospectively analyzed data from 444 gastric cancer patients who underwent gastrectomy at the First Affiliated Hospital of Sun Yat-sen University between January 1994 and December 2005.Preoperative Sll was calculated.The Chi square test or Fisher's exact test was used to determine the relationship between preoperative Sll and clinicopathologic characteristics.Overall survival(OS) rates were estimated using the Kaplan-Meier method,and the effect of Sll on OS was analyzed using the Cox proportional hazards model.Receiver operating characteristic(ROC)curves were used to compare the predictive ability of Sll,NLR,and PLR.Results:Sll equal to or higher than 660 was significantly associated with old age,large tumor size,unfavorable Borrmann classification,advanced tumor invasion,lymph node metastasis,distant metastasis,advanced TNM stage,and high carcino-embryonic antigen level,high neutrophil-lymphocyte ratio,and high platelet-lymphocyte ratio(all P<0.05).High Sll was significantly associated with unfavorable prognosis(P<0.001) and Sll was an independent predictor for OS(P=0.015).Subgroups analysis further showed significant associations between high Sll and short OS in stage Ⅰ,Ⅱ,Ⅲ subgroups(all P<0.05).Sll was superior to NLR and PLR for predicting OS in patients with gastric cancer.Conclusion:Preoperative Sll level is an independent prognostic factor for OS in patients with gastric cancer. | Kang Wang Feiyu Diao Zhijun Ye Xinhua Zhang Ertao Zhai Hui Ren Tong Li Hui Wu Yulong He Shirong Cai Jianhui Chen | 2017 | Chinese Journal of Cancer2017，36，9： | 30 |
| 7 | Efficacy and safety of Xinfeng capsule in patients with rheumatoid arthritis:a multi-center parallel-group double-blind randomized controlled trial显示文摘OBJECTIVE:To evaluate the efficacy and safety of Xinfeng capsule in patients suffering rheumatoid arthritis(RA).METHODS:A multi-center parallel-group designed,double-blind,randomized,controlled trial was conducted.Totally 304 RA patients were assigned to two groups:one group was administered Xinfeng capsule(XFC) plus the placebo of leflunomide and the other given leflunomide(LEF) plus the placebo of XFC for twelve weeks.The clinical and laboratory parameters were compared at baseline and fourth,eighth,and twelfth weeks.RESULTS:After twelve-week treatment,patients in two groups all showed some trend of effectiveness when compared in terms of American Rheumatism Association(ACR) recommended 20%,50%,70%improvement criteria,but it was insignificant.The validity in ameliorate modified disease activity score(DAS28) and laboratory indexes as erythrocyte sedimentation rate(ESR),C-reactive protein(CRP),rheumatoid factor(RF) were also found no difference.The score of health assessment questionnaire(HAQ),self-rating anxiety scale(SAS),self-rating depression scale(SDS) and quality of life questionnaire with rheumatoid arthritis(RAQOL)both lower than the first week and the changes showed no difference.However,the score of SDS dropped more in XFC group than in the other.A total of 147 adverse reaction cases were reported,which shows no difference between the two groups.The most common adverse reactions were hepatic impairment,anemia,leukocytopenia,epigastric discomfort and phalacrosis.CONCLUSION:XFC demonstrated better improvement in the scores of SDS and compared with those of LEF group. | Liu Jian Wang Yuan Huang Chuanbing Xu Jianhua Li Zhijun Xu Liang He Liyun Sun Yue Wang Yali Xu Shengqian Zhao Ping Mao Tongjun Tan Bin Zhu Fubing Zhang Pingheng Fang Li | 2015 | Journal of Traditional Chinese Medicine2015，35，5： | 27 |
| 8 | Sleep and Cognitive Abnormalities in Acute Minor Thalamic Infarction显示文摘In order to characterize sleep and the cognitive patterns in patients with acute minor thalamic infarction(AMTI), we enrolled 27 patients with AMTI and 12 matched healthy individuals. Questionnaires about sleep and cognition as well as polysomnography(PSG) were performed on days 14 and 90 post-stroke. Compared to healthy controls, in patients with AMTI, hyposomnia was more prevalent; sleep architecture was disrupted as indicated by decreased sleep efficiency, increased sleep latency, and decreased non-rapid eye movement sleep stages 2 and 3;more sleep-related breathing disorders occurred; and cognitive functions were worse, especially memory. While sleep apnea and long-delay memory recovered to a large extent in the patients, other sleep and cognitive function deficit often persisted. Patients with AMTI are at an increased risk for hyposomnia, sleep structure disturbance,sleep apnea, and memory deficits. Although these abnormalities improved over time, the slow and incomplete improvement suggest that early management should be considered in these patients. | Wei Wu Linyang Cui Ying Fu Qianqian Tian Lei Liu Xuan Zhang Ning Du Ying Chen Zhijun Qiu Yijun Song Fu-Dong Shi Rong Xue | 2016 | Neuroscience Bulletin2016，32，4： | 28 |
| 9 | Exploring atmospheric free-radical chemistry in China:the self-cleansing capacity and the formation of secondary air pollution显示文摘Since 1971,it has been known that the atmospheric free radicals play a pivotal role in maintaining the oxidizing power of the troposphere.The existence of the oxidizing power is an important feature of the troposphere to remove primary air pollutants emitted from human beings as well as those from the biosphere.Nevertheless,serious secondary air-pollution incidents can take place due to fast oxidation of the primary pollutants.Elucidating the atmospheric free-radical chemistry is a demanding task in the field of atmospheric chemistry worldwide,which includes two kinds of work:first,the setup of reliable radical detection systems;second,integrated field studies that enable closure studies on the sources and sinks of targeted radicals such as OH and NO3.In this review,we try to review the Chinese efforts to explore the atmospheric free-radical chemistry in such chemical complex environments and the possible link of this fast gas-phase oxidation with the fast formation of secondary air pollution in the city-cluster areas in China. | Keding Lu Song Guo Zhaofeng Tan Haichao Wang Dongjie Shang Yuhan Liu Xin Li Zhijun Wu Min Hu Yuanhang Zhang | 2019 | National Science Review2019，6，3： | 26 |
| 10 | Effects of clay and calcium ions on coal flotation显示文摘The microflotation of three single minerals,mixed coal–kaolinite and mixed coal–montmorillonite were examined to study the effects of clay and calcium ions on coal flotation.The results show that the ash content of flotation concentrate increases by 3%in the presence of clay minerals,and the ash content would further increase by 3%in co-presence of clay minerals and high concentration of Ca2+.Scanning electron microscope(SEM)images and elemental spectrum analysis indicate that fne clay particles that coat on the coal surface,which is called slime coating,can affect the coal flotation.The slime coating would be induced much more easily in the presence of Ca2+. | Zhang Zhijun Liu Jiongtian Xu Zhiqiang Ma Liqiang | 2013 | International Journal of Mining Science and Technology2013，23，5： | 24 |
| 11 | Inflammatory Cytokines and Alzheimer's Disease: A Review from the Perspective of Genetic Polymorphisms显示文摘Neuroinflammatory processes are a central feature of Alzheimer's disease(AD) in which microglia are over-activated, resulting in the increased production of proinflammatory cytokines. Moreover, deficiencies in the antiinflammatory system may also contribute to neuroinflammation. Recently, advanced methods for the analysis of genetic polymorphisms have further supported the relationship between neuroinflammatory factors and AD risk because a series of polymorphisms in inflammation-related genes have been shown to be associated with AD. In this review, we summarize the polymorphisms of both pro- and anti-inflammatory cytokines related to AD, primarily interleukin-1(IL-1), IL-6, tumor necrosis factor alpha, IL-4, IL-10, and transforming growth factor beta, as well as their functional activity in AD pathology. Exploration of the relationship between inflammatory cytokine polymorphisms and AD risk may facilitate our understanding of AD pathogenesis and contribute to improved treatment strategies. | Fan Su Feng Bai Zhijun Zhang | 2016 | Neuroscience Bulletin2016，32，5： | 22 |
| 12 | Source Separation of Diesel Engine Vibration Based on the Empirical Mode Decomposition and Independent Component Analysis显示文摘Vibration signals from diesel engine contain many different components mainly caused by combustion and mechanism operations,several blind source separation techniques are available for decomposing the signal into its components in the case of multichannel measurements,such as independent component analysis(ICA).However,the source separation of vibration signal from single-channel is impossible.In order to study the source separation from single-channel signal for the purpose of source extraction,the combination method of empirical mode decomposition(EMD) and ICA is proposed in diesel engine signal processing.The performance of the described methods of EMD-wavelet and EMD-ICA in vibration signal application is compared,and the results show that EMD-ICA method outperforms the other,and overcomes the drawback of ICA in the case of single-channel measurement.The independent source signal components can be separated and identified effectively from one-channel measurement by EMD-ICA.Hence,EMD-ICA improves the extraction and identification abilities of source signals from diesel engine vibration measurements. | DU Xianfeng LI Zhijun BI Fengrong ZHANG Junhong WANG Xia SHAO Kang | 2012 | Chinese Journal of Mechanical Engineering2012，25，3： | 21 |
| 13 | The trend on runoff variations in the Lhasa River Basin显示文摘作为一个学习区域在西藏的高原在拉萨水文学车站上面拿拉萨河盆,年度、每月的吝啬的流量的特征在 1956 ¨ C 期间, 2003 被分析。 | LIN Xuedong ZHANG Yili YAO Zhijun GONG Tongliang WANG Hong CHU Duo LIU Linshan ZHANG Fei | 2008 | Journal of Geographical Sciences2008，18，1： | 18 |
| 14 | Disentangling the effects of topography and space on the distributions of dominant species in a subtropical forest显示文摘Topography and space are two important factors determining plant species assemblages in forest communities.Quantification of the contribution of these two factors in determining species distribution helps us to evaluate their relative importance in determining species assemblages.This study aims to disentangle the effect of topography and space on the distributions of 14 dominant species in a subtropical mixed forest.Spearman correlation analysis and the torustranslation test were used to test the species–habitat associations.Variation partitioning was used to quantify the relative contributions of topography and space at three sampling scales and three life stages.Correlation analyses and torus-translation tests showed species abundance was mostly correlated with topographic wetness index,vertical distance from the channel network and convexity.Variation partitioning showed that pure topography,pure space and spatially structured topography explained about 2.1 %,41.2 % and 13.8 %of the variation in species distributions,respectively.For nine species,total topography fractions peaked in 20 m quadrats.For ten species,the pure space fractions peaked in 50 m quadrats.For many species,the total topography fraction andthe pure space fraction were larger for the most abundant life stages,which reflected the importance of sampling effect.However,some cases did not follow this trend suggesting that the effects of ecological processes such as habitat filtering,density dependence or dispersal limitation may exceed the sampling effects.In conclusion,we found that spatially structured topography and pure space primarily shaped the distribution of dominant tree species.Furthermore,their effects were both scale- and life stage-dependent. | Qinggang Wang Yaozhan Xu Zhijun Lu Dachuan Bao Yili Guo Junmeng Lu Kuihan Zhang Haibo Liu Hongjie Meng Xiujuan Qiao Handong Huang Mingxi Jiang | 2014 | Chinese Science Bulletin2014，59，35： | 16 |
| 15 | The Current Situation on Major Depressive Disorder in China:Research on Mechanisms and Clinical Practice显示文摘Depression is the most disabling disorder worldwide that accounts for the highest proportion of global burden attributable to mental disorders. Major depressive disorder(MDD) is characterized by deep sadness, reduced energy,vegetative nervous system dysregulation, cognitive dysfunction, and even a high suicidal tendency. Although other treatment choices are available, antidepressant medication is the front-line treatment option for MDD. Regarding clinical efficacy, only ~50% of patients respond to frontline antidepressants, and <33% obtain remission. Currently, objective indexes to guide clinical decisions are still lacking. Furthermore, knowledge about the neurobiological mechanisms underlying discrepant antidepressant outcomes is still also fragmentary. In the present review, we discuss the current research progress and clinical opinions on MDD in China. | Zhenghua Hou Wenhao Jiang Yingying Yin Zhijun Zhang Yonggui Yuan | 2016 | Neuroscience Bulletin2016，32，4： | 16 |
| 16 | CSCO guidelines for colorectal cancer version 2022:Updates and discussions显示文摘Colorectal cancer(CRC) is the third most common cancer worldwide and the second most common in tumor-related mortality by Global Cancer Statistics 2020(1). Recent data show that the incidence and mortality of CRC in China are increasing(2-4), with the number of new cases and deaths reaching 607,900 and 261,777 in 2019. | Zhijun Yuan Shanshan Weng Chenyang Ye Hanguang Hu Suzhan Zhang Ying Yuan | 2022 | Chinese Journal of Cancer Research2022，34，2： | 16 |
| 17 | A Novel Chloroplast-Localized Pentatricopeptide Repeat Protein Involved in Splicing Affects Chloroplast Development and Abiotic Stress Response in Rice显示文摘Pentatricopeptide 重复(PPR ) 蛋白质在更高的植物包括一个大家庭并且在 organellar RNA 新陈代谢的各种各样的方面调制 organellar 基因表示 byparticipating。在米饭,家庭包含他们的功能仍然是的 477 个成员,和 majorityof 不清楚。在这研究,我们孤立并且描绘米饭变异的、白条纹叶(wsl ) ,它在开发早的显示萎黄病有条纹或刻痕之状态。基于地图的克隆表明 WSL 编码指向叶绿体的最新识别的米饭 PPR 蛋白质。在 wsl 异种,锐气依赖者质体基因表示是显著地下面调整的,并且质体 rRNAs 和翻译 productsaccumulate 到很底层。一致地与观察, wsl 在叶绿体抄本 rpl2 拼接显示出一个强壮的缺点,在异种导致异常抄本累积和它的产品减小。wsl 显示出提高的敏感到骆驼毛的织物,咸度,和糖,并且它积累更多的 H 2 O 2 比野类型。这些结果建议减少的翻译效率可以影响异种的反应到 abioticstress.Key 词: | Junjie Tan Zhenhua Tan Fuqing Wu Peike Sheng Yueqin Heng Xinhua Wang Yulong Ren Jiulin Wang Xiuping Guo Xin Zhang Zhijun Cheng Ling Jiang Xuanming Liu Haiyang Wang Jianmin Wan | 2014 | Molecular Plant2014，7，8： | 15 |
| 18 | The Qingzang Movement: The major uplift of the Qinghai-Tibetan Plateau显示文摘35 年以前,一个年轻 Qinghai 西藏的高原的想法在 Qinghai 西藏的高原上基于全面调查被建议。这个假设建议高原开始从是高形成在期间的不到 1000 m 的均夷作用表面(寡妇表面) 升起了对上新世中新世。快高举,即, Qingzang 运动,自从 ~ ,开始了 3.6 妈,在高原以内在高原边缘和指责的盆的同步出现附近由巨大的 molasse 存款证实了。然而,以后的研究质问了这个想法并且更早建议了(8, 14 或 35 妈) 巨大的高原地形学的形成。这里,我们重新估计 Qingzang 运动根据我们的以前的结果并且考虑到在最近的十年的新研究。高原边缘被很大的排水受到了集中的切口并且显示出 geomorphological 周期的一个婴儿阶段的风景特征。然而,这些排水没被形成直到 1.71.9 妈;headwater 侵蚀还没到达了高原的内地因此尽管有它的高耸的举起,西藏的内部没有重要侵蚀,并且仍然是旧阶段地形。如果吝啬的侵蚀率等价于排干西藏的高原的现代的河的碎屑状、可溶的分泌物的和,它应该被穿了在下面,忽略在 8.6 妈以内的一块低地构造高举并且均衡。在高原边缘附近的巨大的集团企业在大约 3.6 妈开始了到沉积物,显示在那时间以后的增加的消除。而且, Hipparion 动物志地点广泛地被散布,并且大象,长颈鹿,和犀牛充满 Qaidam 盆直到早上新世。新生代气候变化独自不能说明 Hipparion 动物志的稠密的出现,除非西藏的 paleo 举起被降低。自从 Qingzang 运动,西藏的上升在亚洲内部 aridification 上有大影响。 | LI JiJun ZHOU ShangZhe ZHAO ZhiJun ZHANG Jun | 2015 | Science China Earth Sciences2015，58，11： | 15 |
| 19 | Chemical compositions of precipitation and scavenging of particles in Beijing显示文摘Totally 23 precipitation samples were collected in Beijing from May to November in 2003. In order to investigate the chemical composition of precipitation samples, pH, conductivity, concentrations of water-soluble ions and organic acids were analyzed. The average pH of pre-cipitations is 6.18, belonging to the neutral range; the average conductivity is 52.23 μS/cm, which indicates that precipitations in Beijing are obviously polluted; SO 24? , NO3 ? are the most abundant anions with the average concentrations of 521 and 174 μeq·L?1, respectively; the average 2SO 4? /NO3? equivalent ratio is 3.1, which decreases by about 15% compared with the result of 1994; NH+ 4 and Ca2+ are the most abundant cations with the average concentrations of 376 and 397 μeq·L?1, respectively; formic acid, acetic acid and oxalic acid are the main organic acids with the average concentrations of 4.62, 4.60 and 1.17 μeq·L?1, respectively, accounting for 2% of the overall anions. Obvious differences between concentrations before and after precipitation are also observed by SJAC (Steam Jet Aerosol Collector), which shows the removal of particles from the atmosphere by precipitation. | HU Min ZHANG Jing WU Zhijun | 2005 | Science China Chemistry2005，48，3： | 15 |
| 20 | Western medication plus Traditional Chinese Medicine preparations in patients with chronic heart failure:a prospective,single-blind,randomized,controlled,and multicenter clinical trial显示文摘OBJECTIVE: To assess the efficacy and safety in patients with chronic heart failure(CHF) of Western medication plus Traditional Chinese Medicine(TCM) preparations.METHODS: This prospective, single-blind, randomized, controlled, and multicenter clinical trial began on September 17, 2008, and was completed on June 25, 2011. A total of 340 inpatients, aged 40-79 years, with exacerbating CHF from 10 hospitals were enrolled and randomly allocated within 24 h of admission. The trial included three intervention periods. During hospitalization, the control group received western medication for CHF and the treatment group received Danhong injection with Shenfu injection or Shenmai injection. After discharge,all patients were treated with Qiliqiangxin capsules and Buyiqiangxin tablets or a placebo for 6 months. After the 6-month intervention, both groups received only continuous western medication. The primary endpoint was all-cause mortality.The efficacy assessments were as follows: B-type natriuretic peptide(BNP), Lee's HF score, the 6-minute walking test(6 MWT), left ventricular ejection fraction(LVEF), and the Minnesota Living with Heart Failure Questionnaire(MLHFQ). The safety assessments were as follows: blood and urine routine examination, hepatic and renal function, electrolytes in blood and adverse events.RESULTS: Compared with the control group, the treatment group showed a 30.99% reduction in all-cause mortality and an improved survival rate.The treatment group showed greater improvement in 6 MWT(P = 0.02) than the control group on discharge, after 12-month follow-up, there was a time-group interaction for MLHFQ(P = 0.03). Incidence rate of adverse events and other relevant safety indexes were not statistically significant between the two groups.CONCLUSION: Western medication plus TCM treatment can increase 6-minute walking distance(improve exercise tolerance) and quality of life with heart failure patients. | Wang Xianliang Hou Yazhu Mao Jingyuan Zhao Yingqiang Niu Tianfu Yuan Ruyu Wang Yonggang Cui Jin-rong Shi Le Jia Xiuli Fan Ruihong Lin Qian Zhang Yan Li Zhijun Shang Hongcai Wang Baohe Wang Hongwu Wang Henghe Cui Xiaolei Soh Shanbin Ruan Jishou Zhang Boli | 2017 | Journal of Traditional Chinese Medicine2017，37，6： | 15 |
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