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| 1 | Traditional Chinese medicine in COVID-19显示文摘COVID-19 pandemic caused by severe acute respiratory syndrome coronavirus 2(SARSCo V-2)has spread across the globe,posing an enormous threat to public health and safety.Traditional Chinese medicine(TCM),in combination with Western medicine(WM),has made important and lasting contributions in the battle against COVID-19.In this review,updated clinical effects and potential mechanisms of TCM,presented in newly recognized three distinct phases of the disease,are summarized and discussed.By integrating the available clinical and preclinical evidence,the efficacies and underlying mechanisms of TCM on COVID-19,including the highly recommended three Chinese patent medicines and three Chinese medicine formulas,are described in a panorama.We hope that this comprehensive review not only provides a reference for health care professionals and the public to recognize the significant contributions of TCM for COVID-19,but also serves as an evidence-based in-depth summary and analysis to facilitate understanding the true scientific value of TCM. | Ming Lyu Guanwei Fan Guangxu Xiao Taiyi Wang Dong Xu Jie Gao Shaoqin Ge Qingling Li Yuling Ma Han Zhang Jigang Wang Yuanlu Cui Junhua Zhang Yan Zhu Boli Zhang | 2021 | Acta Pharmaceutica Sinica B2021，11，11： | 14 |
| 2 | Constraints on the Ediacaran-Cambrian boundary in deep-water realm in South China: Evidence from zircon CA-ID-TIMS U-Pb ages from the topmost Liuchapo Formation显示文摘The placement of the Ediacaran-Cambrian boundary in deep-water realm in South China and the high-precision temporal framework for the Ediacaran-Cambrian transition in this region have not yet been completely solved. Recently, we have found two K-bentonite beds in the top of the Liuchapo Formation at the Pingyin section, Guizhou Province. It provides an opportunity for constructing the temporal framework of the transitional strata on the Yangtze Platform in South China and for determining the Ediacaran-Cambrian boundary in this area. In this study, we conducted high-precision CA-ID-TIMS U-Pb dating on zircons from the two K-bentonites. The ages of the two K-bentonites were precisely constrained at 536.40±0.47/1.1/1.2 Ma(2σ, n=7, MSWD=0.92) and 541.48±0.46/1.1/1.2 Ma(2σ, n=8, MSWD=1.3). Combining the geochronological results with organic carbon isotope data of chert in the topmost Liuchapo Formation from the section, we suggest that the EdiacaranCambrian boundary should be consistent with a significant negative organic carbon isotope excursion between the two Kbentonites. The scheme of the Ediacaran-Cambrian boundary in this study is of great significance for global correlation, and further for unravelling the information of the terminal Ediacaran-early Cambrian ocean. | Wei WANG Mingzhong ZHOU Zhuyin CHU Junjie XU Chaofeng LI Taiyi LUO Jinghui GUO | 2020 | Science China Earth Sciences2020，63，8： | 4 |
| 3 | Effects of lead and cadmium co-exposure on bone mineral density in a Chinese population显示文摘 | Xiao Chen Keyue Wang Zhongqiu Wang Caohui Gan Ping He Yihuai Liang Taiyi Jin Guoying Zhu | 2014 | Bone2014，，： | 1 |
| 4 | Effects of Cadmium on Bone Mineral Density in the Distal and Proximal Forearm: Two Female Population Studies in China显示文摘 | Xiao Chen Guoying Zhu Taiyi Jin Zhongqiu Wang | 2013 | Biological Trace Element Research (-)2013，，1： | 1 |
| 5 | Multiuser MIMO OFDM Based TDD/TDMA for Next Generation Wireless Communication Systems显示文摘 | Lu Zhaogan Rao Yuan Zhang Taiyi Wang Liejun | 2010 | Wireless Personal Communications2010，52，2： | 1 |
| 6 | Effect of Yinlai Decoction on the metabolic pathways in the lung of high-calorie diet-induced pneumonia rats显示文摘Objective:To search for specific metabolites in the lungs of pneumonia rats fed with a high-calorie diet,as well as explore the changes in the lung metabolites of young rats treated with Yinlai Decoction(YD)and its effects on inflammation-related metabolic pathways.Methods:Lipopolysaccharides(LPS)and a special high-calorie diet were used to induce Sprague Dawley(SD)rats to simulate the intestinal state of infant pneumonia.Liquid chromatography-mass spectrometry technology(LC-MS/MS)was used to detect metabolites in each group.Supervised orthogonal partial least squares discriminant analysis(OPLS-DA)model values were used for the detection results to find the differential metabolites.The metabolic pathways that are involved with the differential metabolites were clarified through enrichment analysis and topological analysis.Finally,the T cell receptor signaling pathway(TCR)signal conversion was analyzed by the network pharmacology method.Results:In the high-calorie diet combined with pneumonia group(M3),a total of 55 metabolites were determined to be different from the normal group(N).A total of 36 metabolites were determined to be different from those in the lung metabolites of the YD treatment group(T1).YD had a regulatory effect on glutathione metabolism,arginine and proline metabolism,ascorbic acid and aldehyde metabolism and phenylalanine metabolism.And the small molecule metabolites could act on the FYN and lymphocytespecific protein tyrosine kinase(LCK)target proteins in the TCR signaling pathway,thereby affecting the immune function of the lungs.Conclusion:A high-calorie diet can cause abnormal sphingolipid metabolism in the lungs of young rats,thereby creating chronic lung inflammation in young rats.YD has a beneficial effect when used to treat young rats with LPS-induced pneumonia fed on high-calorie diets.Its mechanisms of action may affect the body’s immune pathways by regulating the oxidative stress pathway affected by glutathione metabolism. | Fuyang Xian Tiegang Liu Chen Bai Guannan Yang Xueyan Ma Bochuan Wang Ling Huang Shaoyang Liu Jianhua Zhen Jianzhen He He Yu Yuling Ma Taiyi Wang Xiaohong Gu | 2021 | Journal of Traditional Chinese Medical Sciences2021，8，1： | 1 |
| 7 | A Case of Acute HIV-1 and Monkeypox Coinfection After Condomless Insertive Anal Sex in the Previous 69 Days—Beijing Municipality,China,August-October,2023显示文摘Summary What is already known about this topic?The prevalence of monkeypox(mpox)infections is primarily observed among young men who engage in sexual activities with other men,and there is a possibility of sexual transmission.Co-occurring sexually transmitted infections have also been documented.What is added by this report?In this report,we present a case of a patient in China who was simultaneously diagnosed with mpox,and acute human immunodeficiency virus(HIV)infection. | Lin Jia Han Jia Yuan Fang Benyong Yan Mei Zhang Yang Zhang Wen Wang Caiping Guo Xiaojie Huang Tong Zhang Taiyi Jiang | 2024 | China CDC weekly2024，6，7： | 0 |
| 8 | New insight into immune checkpoint inhibitors in the treatment of advanced renal cell carcinoma显示文摘Kidney cancer,accounting for 4%of all new cancer cases in men and 3%in women,is one of the ten most frequently diagnosed cancer types,of which renal cell carcinoma(RCC)is the most frequent kind of kidney cancer(responsible for70%of adult renal cancer cases).Before the development of immune checkpoint inhibitors(ICIs),RCC was considered an immunoreactive tumor and treated with IL-2 and other immunotherapies. | Hu Wang Zhiqiang Zhu Yihang Zhang Taiyi Jiang Mengmeng Zhang Zongping Wang Yu Zhang An Zhao Bin Su | 2023 | Science China(Life Sciences)2023，66，4： | 0 |
| 9 | MULTI-RESOLUTION LEAST SQUARES SUPPORT VECTOR MACHINES显示文摘The Least Squares Support Vector Machines (LS-SVM) is an improvement to the SVM. Combined the LS-SVM with the Multi-Resolution Analysis (MRA),this letter proposes the Multi-resolution LS-SVM (MLS-SVM).The proposed algorithm has the same theoretical framework as MRA but with better approximation ability.At a fixed scale MLS-SVM is a classical LS-SVM,but MLS-SVM can gradually approximate the target function at different scales.In experiments,the MLS-SVM is used for nonlinear system identification,and achieves better identification accuracy. | Wang Liejun Zhang Taiyi Zhou Yatong | 2007 | Journal of Electronics(China)2007，24，5： | 0 |
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