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| 1 | Multi-Strategy Dynamic Spectrum Access in Cognitive Radio Networks: Modeling, Analysis and Optimization显示文摘Dynamic spectrum access(DSA) based on cognitive radios(CR) technique is an effective approach to address the 'spectrum scarcity' issue. However, traditional CR-enabled DSA system employs only single DSA strategy, which might not be suited to the dynamic network environment. In this paper, we propose a multi-strategy DSA(MS-DSA) system, where the primary and the secondary system share spectrum resources with multiple DSA strategies simultaneously. To analyze the performance of the proposed MS-DSA system, we model it as a continuous-time Markov chain(CTMC) and derive the expressions to compute the corresponding performance metrics. Based on this, we define a utility function involving the concerns of effective throughput, interference quantity on primary users, and spectrum leasing cost. Two optimization schemes, named as spectrum allocation and false alarm probability selection, are proposed to maximize the utility function. Finally, numerical simulations are provided to validate our analysis and demonstrate that the performance can be significantly improved caused by virtues of the proposed MS-DSA system. | Yi Yang Qinyu Zhang Ye Wang Takahiro Emoto Masatake Akutagawa Shinsuke Konaka | 2019 | China Communications2019，16，3： | 9 |
| 2 | Adaptive Resources Allocation Algorithm Based on Modified PSO for Cognitive Radio System显示文摘Radio spectrum has become a rare resource due to the rapid development of wireless communication technique. Cognitive radio is one of important techniques to deal with this radio spectrum problem. But the resource allocation in cognitive radio also has its own issues, such as the flexibility of the allocation algorithm, the performance of resource allocation, and so on. In order to increase the flexibility of the allocation algorithm for cognitive radio, more and more researches are focusing on the evolutionary algorithms, such as genetic algorithm(GA), particle swarm optimization(PSO). Evolutionary algorithm can greatly improve the flexibility of the allocation algorithm for cognitive radio system in different communication scenarios, but the performances are relatively lower than the original mathematical methods. So in this paper, we proposed an adaptive resource allocation algorithm based on modified PSO for cognitive radio system to solve these problems. Modified particle swarm optimization(Modified PSO) has both genetic algorithm(GA) and particle swarm optimization(PSO)’s updating processes which makes this modified PSO overcame PSO’s own disadvantages and keep advantages. Simulation results showed our proposed algorithm has enough flexibility to meet cognitive radio systems’ requirements, and also has a better performance than original PSO. | Yi Yang Qinyu Zhang Ye Wang Takahiro Emoto Masatake Akutagawa Shinsuke Konaka | 2019 | China Communications2019，16，5： | 9 |
| 3 | 3D bioprinting of a biomimetic meniscal scaffold for application in tissue engineering显示文摘Appropriate biomimetic scaffolds created via 3D bioprinting are promising methods for treating damaged menisci.However,given the unique anatomical structure and complex stress environment of the meniscus,many studies have adopted various techniques to take full advantage of different materials,such as the printing combined with infusion,or electrospining,to chase the biomimetic meniscus,which makes the process complicated to some extent.Some researchers have tried to tackle the challenges only by 3D biopringting,while its alternative materials and models have been constrained.In this study,based on a multilayer biomimetic strategy,we optimized the preparation of meniscus-derived bioink,gelatin methacrylate(GelMA)/meniscal extracellular matrix(MECM),to take printability and cytocompatibility into account together.Subsequently,a customized 3D bioprinting system featuring a dual nozzle+multitemperature printing was used to integrate the advantages of polycaprolactone(PCL)and meniscal fibrocartilage chondrocytes(MFCs)-laden GelMA/MECM bioink to complete the biomimetic meniscal scaffold,which had the best biomimetic features in terms of morphology and components.Furthermore,cell viability,mechanics,biodegradation and tissue formation in vivo were performed to ensure that the scaffold had sufficient feasibility and functionality,thereby providing a reliable basis for its application in tissue engineering. | Zhou Jian Tian Zhuang Tian Qinyu Peng Liqing Li Kun Luo Xujiang Wang Diaodiao Yang Zhen Jiang Shuangpeng Sui Xiang Huang Jingxiang Liu Shuyun Hao Libo Tang Peifu Yao Qi Guo Quanyi | 2021 | Bioactive Materials2021，6，6： | 3 |
| 4 | Linking Observations of the Asian Monsoon to the Indian Ocean SST: Possible Roles of Indian Ocean Basin Mode and Dipole Mode显示文摘 | Yang Jianling Liu Qinyu Liu Zhengyu | 2010 | Journal of Climate2010，，21： | 2 |
| 5 | Basin mode of Indian Ocean sea surface temperature and Northern Hemisphere circumglobal teleconnection显示文摘 | Yang Jianling Liu Qinyu Liu Zhengyu Wu Lixin Huang Fei | 2009 | Geophysical Research Letters2009，，19： | 2 |
| 6 | Deterministic simulation of UWB indoor propagation channel显示文摘A site-specific model of UWB pulse propagation in indoor environment is addressed. The simula-tion utilizes the principles of geometrical optics (GO) for direct and refiected paths' tracing and the time domain technique for describing the transient electromagnetic field reected from wall, floor, ceiling, and objects. The polarization of the received waveform is determined by taking into account the radiation pattern of the transmitting and receiving antennas, as well as the polarization changes owing to every reflection. The model provides more intrinsical interpretations for UWB pulse propagation in realistic indoor environment. | Wang Yang Zhang Naitong Zhang Qinyu Zhang Zhongzhao | 2008 | Journal of Systems Engineering and Electronics2008，19，3： | 2 |
| 7 | Characterizing Ultra-wide Band indoor line-of-sight wireless channel显示文摘By exploring the deterministic characteristics of the measurement data, a new propagation model with two deterministic clusters and stochastic arriving rays within each cluster is proposed. When considering the cumulative distribution function (CDF) of the three key channel statistics, the proposed model fits the measurement data better than SV/IEEE 802.15.3, a model which is known as a standard model for UWB indoor propagation channel. Therefore, with the additional knowledge of the specific environment geometry, the proposed model generating impulse responses 'resemble' the measured channel impulse responses better than IEEE model. Moreover, the proposed model's parameters obtaining procedure is simplified by utilizing simple parameters of the environment. | Wang Yang Zhang Naitong Zhang Qinyu Zhang Zhongzhao | 2007 | Journal of Systems Engineering and Electronics2007，18，4： | 2 |
| 8 | The Feasibility of Total or Near-Total Bilateral Thyroidectomy for the Treatment of Bilateral Multinodular Goiter显示文摘 | Weiping Yang Tanglei Shao Jiazeng Ding Xiaotai Jin Qinyu Li Peiguo G. Chu Yun Yen Weihua Qiu | 2009 | Investigative Surgery2009，，3： | 1 |
| 9 | Forced Rossby wave in the northern South China Sea显示文摘 | YANG HAIJUN LIU QINYU | 2003 | Deep-Sea Res Ⅰ2003，50，： | 1 |
| 10 | Impact of the Indian Ocean SST basin mode on the Asian summer monsoon显示文摘 | YANG Jianling LIU Qinyu XIE Shangping | 2007 | Geophysical Research Letters2007，，： | 1 |
| 11 | Hierarchical macro-microporous WPU-ECM scaffolds combined with Microfracture Promote in Situ Articular Cartilage Regeneration in Rabbits显示文摘Tissue engineering provides a promising avenue for treating cartilage defects.However,great challenges remain in the development of structurally and functionally optimized scaffolds for cartilage repair and regeneration.In this study,decellularized cartilage extracellular matrix(ECM)and waterborne polyurethane(WPU)were employed to construct WPU and WPU-ECM scaffolds by water-based 3D printing using low-temperature deposition manufacturing(LDM)system,which combines rapid deposition manufacturing with phase separation techniques.The scaffolds successfully achieved hierarchical macro-microporous structures.After adding ECM,WPU scaffolds were markedly optimized in terms of porosity,hydrophilia and bioactive components.Moreover,the optimized WPU-ECM scaffolds were found to be more suitable for cell distribution,adhesion,and proliferation than the WPU scaffolds.Most importantly,the WPU-ECM scaffold could facilitate the production of glycosaminoglycan(GAG)and collagen and the upregulation of cartilage-specific genes.These results indicated that the WPU-ECM scaffold with hierarchical macro-microporous structures could recreate a favorable microenvironment for cell adhesion,proliferation,differentiation,and ECM production.In vivo studies further revealed that the hierarchical macro-microporous WPU-ECM scaffold combined with the microfracture procedure successfully regenerated hyaline cartilage in a rabbit model.Six months after implantation,the repaired cartilage showed a similar histological structure and mechanical performance to that of normal cartilage.In conclusion,the hierarchical macro-microporous WPU-ECM scaffold may be a promising candidate for cartilage tissue engineering applications in the future. | Mingxue Chen YangYang Li Shuyun Liu Zhaoxuan Feng Hao Wang Dejin Yang Weimin Guo Zhiguo Yuan Shuang Gao Yu Zhang Kangkang Zha Bo Huang Fu Wei Xinyu Sang Qinyu Tian Xuan Yang Xiang sui Yixin Zhou Yufeng Zheng Quanyi Guo | 2021 | Bioactive Materials2021，6，7： | 1 |
| 12 | Forced Rossby wave in thenorthern South China Sea显示文摘 | YANG HAIJUN LIU QINYU 2003 | 2003 | Deep-Sea Research PartⅠ2003，50，7： | 1 |
| 13 | Characteristics and development model of karst reservoirs in the fourth member of Sinian Dengying Formation in central Sichuan Basin,SW China显示文摘The reservoir space,types and distribution characteristics of karst carbonate gas reservoirs in the fourth member of Sinian Dengying Formation(Deng 4 Member)in central Sichuan Basin are analyzed based on the drilling,logging and seismic data.A development model of karst reservoirs is constructed to support the high-efficiency development of gas pools.The research shows that the reservoirs in Deng 4 Member have mainly small-scale karst vugs and fractures as storage space,and can be divided into three types,fracture-vug,pore-vug and pore types.The development patterns of the karst reservoirs are determined.On the plane,the karst layers increase from 65 m to 170 m in thickness from the karst platform to the karst slope,and the high-quality reservoirs increase from 25.0 m to 42.2 m in thickness;vertically,the reservoirs at the top of Deng 4 Member appear in multiple layers,and show along-bedding and along fracture dissolution characteristics.The reservoirs at the bottom are characterized by the dissolution parallel to the water level during the karstification period,and have 3-5 large-scale fracture-cave systems.Based on the reservoir development characteristics and the genetic mechanism,three types of reservoir development models of karst reservoir are established,i.e.,bed-dissolved body,fracture-dissolved body and paleohorizon-dissolved body.The construction of karst reservoir development models and seismic response characteristics of the three types of reservoirs can provide parameter for well placement and trajectory design,and substantially improve productivity and development indices of individual wells and gas reservoirs.The designed production capacity of the gas reservoir has enhanced from the initial 3.6 billion to 6 billion cubic meters,making the profit of the reservoir development increase noticeably. | YAN Haijun HE Dongbo JIA Ailin LI Zhiping GUO Jianlin PENG Xian MENG Fankun LI Xinyu ZHU Zhanmei DENG Hui XIA Qinyu ZHENG Guoqiang YANG Shan SHI Xiaomin | 2022 | Petroleum Exploration and Development2022，49，4： | 1 |
| 14 | Dual-AAV split prime editor corrects the mutation and phenotype in mice with inherited retinal degeneration显示文摘The prime editor(PE)can edit genomes with almost any intended changes,including all 12 possible types of base substitutions,small insertions and deletions,and their combinations,without the requirement for double strand breaks or exogenous donor templates.PE demonstrates the possibility of correcting a variety of disease-causing mutations and might expand the therapeutic application of gene editing.In this study,PE was optimized based on a dual-adeno-associated virus(AAV)split-intein system in vitro by screening different split sites and split inteins.We found that splitting PE before amino acid 1105(Ser)of SpCas9 with Rma intein resulted in the highest on-target editing.The orientations of pegRNA and nicking sgRNA in the AAV vector were further optimized.To test the in vivo performance of the optimized dual-AAV split-PE3,it was delivered by subretinal injection in rd12 mice with inherited retinal disease Leber congenital amaurosis.The prime editors corrected the pathogenic mutation with up to 16%efficiency in a precise way,with no detectable off-target edits,restored RPE65 expression,rescued retinal and visual function,and preserved photoceptors.Our findings establish a framework for the preclinical development of PE and motivate further testing of PE for the treatment of inherited retinal diseases caused by various mutations. | Kaiqin She Yi Liu Qinyu Zhao Xiu Jin Yiliu Yang Jing Su Ruiting Li Li Song Jianlu Xiao Shaohua Yao Fang Lu Yuquan Wei Yang Yang | 2023 | Signal Transduction and Targeted Therapy2023，8，3： | 1 |
| 15 | Fiber grating sensors for high-temperature measurement显示文摘 | Ya ge Zhan Hua Wu Qinyu Yang | 2008 | Optics and Lasers in Engineering2008，46，4： | 1 |
| 16 | Linking observations of the Asian monsoon to the Indian O- cean SST: Possible roles of Indian Ocean basin mode and dipole mode 显示文摘 | YANG Jianling LIU Qinyu LIU Zhengyu | 2010 | Journal of Climate2010，23，21： | 1 |
| 17 | Regionaldynamics of seasonal variability in the South China Sea显示文摘 | LIU ZHENGYU YANG HAIJUN LIU QINYU | 2001 | JPhys Oceanogr2001，31，27： | 1 |
| 18 | Fiber Grating Sensors for High-Temperature Measurement显示文摘 | Yage Zhana Hua Wua Qinyu Yang | 2008 | Optics and Lasers in Engi- neering2008，46，1： | 1 |
| 19 | FOXO6 promotes gastric cancer cell tumorigenicity via upregulation of C-myc显示文摘 | Li Qinyu Cui Long Du Zhen-dong Shi Min-min Wu Wei-ze Yang Wei-ping Peng Cheng-hong | 2013 | FEBS Letters2013，，14： | 1 |
| 20 | FOXO6 promotes gastric cancer cell tumorigenicity via upregulation of C-myc显示文摘 | Li Qinyu Cui Long Du Zhen-dong Shi Min-min Wu Wei-ze Yang Wei-ping Peng Cheng-hong | 2013 | FEBS Letters2013，，14： | 1 |
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