|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | A novel approach of testability modeling and analysis for PHM systems based on failure evolution mechanism显示文摘Prognostics and health management (PHM) significantly improves system availability and reliability, and reduces the cost of system operations. Design for testability (DFT) developed concurrently with system design is an important way to improve PHM capability. Testability modeling and analysis are the foundation of DFT. This paper proposes a novel approach of testability modeling and analysis based on failure evolution mechanisms. At the component level, the fault progression-related information of each unit under test (UUT) in a system is obtained by means of failure modes, evolution mechanisms, effects and criticality analysis (FMEMECA), and then the failure-symptom dependency can be generated. At the system level, the dynamic attributes of UUTs are assigned by using the bond graph methodology, and then the symptom-test dependency can be obtained by means of the functional flow method. Based on the failure-symptom and symptom-test dependencies, testability analysis for PHM systems can be realized. A shunt motor is used to verify the application of the approach proposed in this paper. Experimental results show that this approach is able to be applied to testability modeling and analysis for PHM systems very well, and the analysis results can provide a guide for engineers to design for testability in order to improve PHM performance. | Tan Xiaodong Qiu Jing Liu Guanjun Lv Kehong Yang Shuming Wang Chao | 2013 | Chinese Journal of Aeronautics2013，26，3： | 14 |
| 2 | Increasing targeting scope of adenosine base editors in mouse and rat embryos through fusion of TadA deaminase with Cas9 variants显示文摘 | Lei Yang Xiaohui Zhang Liren Wang Shuming Yin Biyun Zhu Ling Xie Qiuhui Duan Huiqiong Hu Rui Zheng Yu Wei Liangyue Peng Honghui Han Jiqin Zhang Wenjuan Qiu Hongquan Geng Stefan Siwko Xueli Zhang Mingyao Liu Dali Li | 2018 | Protein & Cell2018，9，9： | 13 |
| 3 | Assessing the numbers of SNPs needed to establish molecular IDs and characterize the genetic diversityof soybean cultivars derived from Tokachi nagaha显示文摘The development of a core set of SNP molecular markers that could be widely used in soybean genetic research would greatly facilitate research into the genetic diversity of soybean.We conducted an analysis of Tokachi nagaha and 137 of its descendant soybean cultivars using 4044 SNP markers with the goal of determining the appropriate number of single-nucleotide polymorphisms(SNPs)needed to construct unambiguous molecular IDs and characterize genetic diversity based on a genetic distance matrix correlation method.When the number of SNPs was held constant,the number of accession pairs that could be distinguished increased as the polymorphism informative content(PIC)value of the SNPs increased.A core panel of 20 selected SNPs from 11 linkage groups with a mean PIC value of 0.3703 and a range of 0.3640–0.3749 was able to identify almost all of the accession pairs in our study[9445 pairs(99.92%)].The eight accession pairs that could not be identified with this core SNP set all originated from the same province and some of them had the same parental cultivars.The molecular IDs of the 138 accessions were constructed using the core 20 SNPs.It is known that both the number of SNPs and PIC values should be considered when SNPs are selected for use in the analysis of genetic diversity.In this study,when the PIC value was 0.3460,the correlation coefficient between the genetic distance matrices associated with a panel of 200 SNPs and the total population was>0.800,indicating satisfactory correlation.Our high-accuracy,high-resolution core SNP panel for germplasm fingerprinting and our findings about assessing genetic diversity will likely markedly improve the management and utilization efficiency of soybean germplasm resources. | Zhangxiong Liu Jun Li Xuhong Fan Nang Myint Phyu Sin Htwe Shuming Wang Wen Huang Jiyu Yang Lili Xing Lijun Chen Yinghui Li Rongxia Guan Ruzhen Chang Dechun Wang Lijuan Qiu | 2017 | The Crop Journal2017，5，4： | 10 |
| 4 | Sensor Optimization Selection Model Based on Testability Constraint显示文摘Sensor selection and optimization is one of the important parts in design for testability. To address the problems that the traditional sensor optimization selection model does not take the requirements of prognostics and health management especially fault prognostics for testability into account and does not consider the impacts of sensor actual attributes on fault detectability, a novel sensor optimization selection model is proposed. Firstly, a universal architecture for sensor selection and optimization is provided. Secondly, a new testability index named fault predictable rate is defined to describe fault prognostics requirements for testability. Thirdly, a sensor selection and optimization model for prognostics and health management is constructed, which takes sensor cost as objective function and the defined testability indexes as constraint conditions. Due to NP-hard property of the model, a generic algorithm is designed to obtain the optimal solution. At last, a case study is presented to demonstrate the sensor selection approach for a stable tracking servo platform. The application results and comparison analysis show the proposed model and algorithm are effective and feasible. This approach can be used to select sensors for prognostics and health management of any system. | YANG Shuming QIU Jing LIU Guanjun | 2012 | Chinese Journal of Aeronautics2012，25，2： | 4 |
| 5 | Optimization of dynamic sequential test strategy for equipment health management显示文摘Testing is the premise and foundation of realizing equipment health management (EHM). To address the problem that the static periodic test strategy may cause deficient test or excessive test, a dynamic sequential test strategy (DSTS) for EHM is presented. Considering the situation that equipment health state is not completely observable in reality, a DSTS optimization method based on partially observable semi-Markov decision process (POSMDP) is proposed. Firstly, an equipment health state degradation model is constructed by Markov process, and the control limit maintenance policy is also introduced. Secondly, POSMDP is formulated in great detail. And then, POSMDP is converted to completely observable belief semi-Markov decision process (BSMDP) through belief state. The optimal equation and the corresponding optimal DSTS, which minimize the long-run expected average cost per unit time, are obtained with BSMDP. The results of application in complex equipment show that the proposed DSTS is feasible and effective. | Shuming Yang Jing Qiu Guanjun Liu Peng Yang | 2012 | Journal of Systems Engineering and Electronics2012，23，1： | 2 |
| 6 | A novel testability model for health management of heading attitude system显示文摘Prognostics and health management (PHM) is very important to guarantee the reliability and safety of aerospace systems, and sensing and test are the precondition of PHM. Integrating design for testability into early design stage of system early design stage is deemed as a fundamental way to improve PHM performance, and testability model is the base of testability analysis and design. This paper discusses a hierarchical model-based approach to testability modeling and analysis for heading attitude system health management. Quantified directed graph, of which the nodes represent components and tests and the directed edges represent fault propagation paths, is used to describe fault-test dependency, and quantitative testability information is assigned to nodes and directed edges. The fault dependencies between nodes can be obtained by functional fault analysis methodology that captures the physical architecture and material flows such as energy, heat, data, and so on. By incorporating physics of failure models into component, the dynamic process of a failing or degrading component can be projected onto system behavior, i.e., system symptoms. Then, the analysis of extended failure modes, mechanisms and effects is utilized to construct fault evolution-test dependency. Using this integrated model, the designers and system analysts can assess the test suite's fault detectability, fault isolability and fault predictability. And heading attitude system application results show that the proposed model can support testability analysis and design for PHM very well. | Liu Guanjun Yang Shuming Qiu Jing Yang Peng | 2013 | Chinese Journal of Aeronautics2013，26，1： | 2 |
| 7 | Almost {actoriz- able IC quasi-adequate semigroups显示文摘 | Qiu Shuming Hartmann M Guo Xiaoiiang | 2011 | Communication in AI gchra2011，39，： | 1 |
| 8 | Organ dose conversion coefficients for external neutron irradiation based on the Chinese mathematical phantom (CMP) 显示文摘 | QIU Rui LI Junli HUANG Shuming | 2012 | Journal of Nuclear Science and Technology2012，49，2： | 1 |
| 9 | Correction to: Increasing targeting scope of adenosine base editors in mouse and rat embryos through fusion of TadA deaminase with Cas9 variants显示文摘This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://gffzzeb6f7f563f66445dh09kxo59qvowk6600.ffgz.tsg.suse.edu.cn/ licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. | Lei Yang Xiaohui Zhang Liren Wang Shuming Yin Biyun Zhu Ling Xie Qiuhui Duan Huiqiong Hu Rui Zheng Yu Wei Liangyue Peng Honghui Han Jiqin Zhang Wenjuan Qiu Hongquan Geng Stefan Siwko Xueli Zhang Mingyao Liu Dali Li | 2019 | Protein & Cell2019，10，9： | 0 |
| 10 | Enhanced genome editing to ameliorate a genetic metabolic liver disease through co-delivery of adeno-associated virus receptor显示文摘Genome editing through adeno-associated viral(AAV) vectors is a promising gene therapy strategy for various diseases,especially genetic disorders. However, homologous recombination(HR) efficiency is extremely low in adult animal models. We assumed that increasing AAV transduction efficiency could increase genome editing activity, especially HR efficiency, for in vivo gene therapy. Firstly, a mouse phenylketonuria(PKU) model carrying a pathogenic R408W mutation in phenylalanine hydroxylase(Pah) was generated. Through co-delivery of the general AAV receptor(AAVR), we found that AAVR could dramatically increase AAV transduction efficiency in vitro and in vivo. Furthermore, co-delivery of SaCas9/sgRNA/donor templates with AAVR via AAV8 vectors increased indel rate over 2-fold and HR rate over 15-fold for the correction of the single mutation in Pah;mice. Moreover, AAVR co-injection successfully increased the site-specific insertion rate of a 1.4 kb Pah cDNA by 11-fold, bringing the HR rate up to 7.3% without detectable global off-target effects. Insertion of Pah cDNA significantly decreased the Phe level and ameliorated PKU symptoms. This study demonstrates a novel strategy to dramatically increase AAV transduction which substantially enhanced in vivo genome editing efficiency in adult animal models, showing clinical potential for both conventional and genome editing-based gene therapy. | Shuming Yin Lie Ma Tingting Shao Mei Zhang Yuting Guan Liren Wang Yaqiang Hu Xi Chen Honghui Han Nan Shen Wenjuan Qiu Hongquan Geng Yongguo Yu Shichang Li Weishi Yu Mingyao Liu Dali Li | 2022 | Science China(Life Sciences)2022，65，4： | 0 |
| 11 | Role of Livestock Sector in the Socio-Economic Uplift of the Rural Pakistan显示文摘 | Tunio Muhammad Tarique Shuming Yang Mohsina Zubair Jing Qiu Gang Chen Ailiang Chen | 2012 | Journal of Agricultural Science and Technology(A)2012，2，10： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员