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| 1 | Duodenal gangliocytic paraganglioma with lymph node metastases: a case report and comparative review of 31 cases显示文摘Gangliocytic paraganglioma(GP) is a rare tumor of uncertain origin most often located in the second portion of the duodenum. It is composed of three cellular components: Epithelioid endocrine cells, spindlelike/sustentacular cells, and ganglion-like cells. While this tumor most often behaves in a benign manner, cases with metastasis are reported. We describe the case of a 62-year-old male with a periampullary GP with metastases to two regional lymph nodes who was successfully treated with pancreaticoduodenectomy. Using Pub Med, EMBASE, EBSCOhost MEDLINE and CINAHL, and Google Scholar, we searched the literature for cases of GP with regional lymph node metastasis and evaluated the varying presentations, diagnostic workup, and disease management of identified cases. Thirty-one cases of GP with metastasis were compiled(30 with at least lymph node metastases and one with only distant metastasis to bone), with age at diagnosis ranging from 16 to 74 years. Ratio of males to females was 19:12. The most common presenting symptoms were abdominal pain(55%) and gastrointestinal bleeding or sequelae(42%). Twenty-five patients underwent pancreaticoduodenectomy. Five patients were treated with local resection alone. One patient died secondary to metastatic disease, and one died secondary to perioperative decompensation. The remainder did well, with no evidence of disease at follow-up from the most recent procedure(except two in which residual disease was deliberately left behind). Of the 26 cases with sufficient histological description, 16 described a primary tumor that infiltrated deep to the submucosa, and 3 described lymphovascular invasion. Of the specific immunohistochemistry staining patterns studied, synaptophysin(SYN) stained all epithelioid endocrine cells(18/18). Neuron specific enolase(NSE) and SYN stained most ganglion-like cells(7/8 and 13/18 respectively), and S-100 stained all spindle-like/sustentacular cells(21/21). Our literature review of published cases of GP with lymph node metastasis underscores the excellent prognosis of GP regardless of specific treatment modality. We question the necessity of aggressive surgical intervention in select patients, and argue that local resection of the mass and metastasis may be adequate. We also emphasize the importance of pre-surgical assessment with imaging studies, as well as post-surgical follow-up surveillance for disease recurrence. | Sahara J Cathcart Aaron R Sasson Jessica A Kozel Jennifer M Oliveto Quan P Ly | 2017 | World Journal of Clinical Cases2017，5，6： | 9 |
| 2 | Characteriza-tion of Products Recycling from PCB Waste Pyrolysis显示文摘 | QUAN C LI A M GAO N B | 2010 | Journal of Analytical and Applied Pyrolysis2010，89，： | 1 |
| 3 | ACORGA ZNX50- a new selective reagent for the solvent extraction ofzinc from chloride leach solutions显示文摘 | Dalton R F Burgess A Quan P M | 1992 | Hydrometallurgy1992，30，13： | 1 |
| 4 | Loss of Halophytism by Interference with SOS1 Expression1[W][OA]显示文摘 | Oh Dong-Ha Leidi Eduardo Zhang Quan Hwang Sung-Min Li Youzhi Quintero Francisco J Jiang Xingyu D’Urzo Matilde Paino Lee Sang Yeol Zhao Yanxiu Bahk Jeong Dong Bressan Ray A Yun Dae-Jin Pardo José M Bohnert Hans J | 2009 | Plant Physiology2009，，1： | 1 |
| 5 | Numerical simulation of long rods impacting silicon carbide targets using J H-1 model显示文摘 | Quan X Clegg R A Cowler M S | 2006 | International Journal of Impact Engineering2006，33，112： | 1 |
| 6 | Protective immunization of horses with a recombinant canarypox virus vectored vaccine co-expressing genes encoding the outer capsid proteins of African horse sickness virus显示文摘 | Guthrie A J Quan M Lourens C W | 2009 | Vaccine2009，27，44： | 1 |
| 7 | Uptake and distribution of N, P and heavy metals In three dominant salt marsh macrophytes from Yangtze River estuary,China显示文摘 | QUAN W M H AN J D SHEN A L | 2007 | Marine Environmental Research2007，64，： | 1 |
| 8 | Fluorination of chorofluoroether using catalysts supported by porous aluminum fluoride显示文摘 | Sekiya A Quan H D Tamura M | 2001 | J Fluorine Chem2001，112，： | 1 |
| 9 | Glucose determination by a pulsed photoacoustic technique:an experimental study using a gelatin-based tissue phantom显示文摘 | K M Quan G B Christison H A Mac Kenzie P Hodgson | 1993 | Physics in medicine and biology1993，38，12： | 1 |
| 10 | Protective immunization of horses with a recombinant canarypox virus vectored vaccine co-ex- pressing genes encoding the outer capsid proteins of African horse sickness virus 显示文摘 | Guthrie A J Quan M Lourens C W | 2009 | Vaccine2009，27，： | 1 |
| 11 | The renal nerve is required for regulation of proximal tubule transport by intraluminally produced Ang II 显示文摘 | Quan A Baum M | 2001 | Am J Physiol Renal Physiol2001，280，3： | 1 |
| 12 | Resistance of epiphyseal cartilage to invasion by osteosareoma is likely to be due to expression of antiangiogenic factors显示文摘 | Quan G M Ojaimi J Nadesapillai A P | 2003 | Pathobiology2003，70，6： | 1 |
| 13 | TG-FTIR and Py-GC/MS analysis on pyrolysis and combustion of pine sawdust显示文摘 | GAO N B LI A M QUAN C | 2013 | Journal of analytical and applied pyrolysis2013，100，： | 1 |
| 14 | Sessile invertebrate and benthic macrofauna community development on a created inlcrtidal oyster (Crassostrea ariakensis) reef in the Yangtze River estuary, China显示文摘 | Quan W M Humphries A T Shen X Q | 2012 | Journal of Shellfish Research2012，31，3： | 1 |
| 15 | Automatic fuzzy ontology generation for semantic web 显示文摘 | Quan T T Hui S C Fong A C M | 2006 | IEEE Trans on Knowledge and Data Engineering2006，18，6： | 1 |
| 16 | Numerical simulation oflong rods impacting silicon carbide targets using JH-1 model显示文摘 | Quan X Clegg R A Cowler M S | 2006 | International Journal of Impact Engineering2006，33，1： | 1 |
| 17 | Changes in psychosocial functioning 1 year after mastectomy alone, delayed breast recon- struction,or immediate breast reconstruction显示文摘 | Metealfe K A Semple J Quan M L | 2012 | Ann Surg Oncol2012，19，1： | 1 |
| 18 | Role of ambulatory blood pressure monitoring in the management of hypertension显示文摘 | Chavanu K Merkel J Quan A M | 2008 | Am J Health Syst Pharm2008，65，3： | 1 |
| 19 | Hepatitis C virus infection in patients infected with human immunodefieieney virus 显示文摘 | Quan C M Grigoriew G A | 1993 | Clin Infect Dis1993，17，1： | 1 |
| 20 | Pressure acid leaching of arid-region laterite ore (Ⅱ):Effect of ore type显示文摘 | WHITTINGTON B I JOHNSON J A QUAN L P MCDONALD R G MUIR D M | 2003 | Hydrometallurgy2003，70，： | 1 |
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