|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | FHY3 and FAR1 Integrate Light Signals with the miR156-SPL Module-Mediated Aging Pathway to Regulate Arabidopsis Flowering显示文摘In response to competition for light from their neighbors,shade-intolerant plants flower precociously to ensure reproductive success and survival.However,the molecular mechanisms underlying this key developmental switch are not well understood.Here,we show that a pair of Arabidopsis transcription factors essential for phytochrome A signaling,FAR-RED ELONGATED HYPOCOTYL3(FHY3)and FAR-RED IMPAIRED RESPONSE1(FAR1),regulate flowering time by integrating environmental light signals with the miR156-SPL module-mediated aging pathway.We found that FHY3 and FAR1 directly interact with three flowering-promoting SQUAMOSA-PROMOTER BINDING PROTEIN-LIKE(SPL)transcription factors,SPL3,SPL4,and SPL5,and inhibit their binding to the promoters of several key flowering regulatory genes,including FRUITFUL(FUL),LEAFY(LFY),APETALA1(AP1),and MIR172C,thus downregulating their transcript levels and delaying flowering.Under simulated shade conditions,levels of SPL3/4/5 proteins increase,whereas levels of FHY3 and FAR1 proteins decline,thus releasing SPL3/4/5 from FHY3/FAR1 inhibition to allow activation of FUL,LFY,AP1,and MIR172C and,consequently,early flowering.Taken together,these results unravel a novel mechanism whereby plants regulate flowering time by integrating environmental cues(such as light conditions)and an internal developmental program(the miR156-SPL module-mediated aging pathway). | Yurong Xie Qin Zhou Yongping Zhao Quanquan Li Yang Liu Mengdi Ma Baobao Wang Rongxin Shen Zhigang Zheng Haiyang Wang | 2020 | Molecular Plant2020，13，3： | 8 |
| 2 | Effects of Technological Parameters on Carbothermal Reduction and Nitridation of Zircon显示文摘Carbothermal reduction and nitridation(CRN)of zircon(ZrSiO4)permits obtaining different composites of oxides and nitrides such as ZrO2-Si2N2O and ZrN-Si3N4.The effects of technological parameters(carbon source,reaction temperature,and carbon content)on the reaction rate and product phase composition of CRN of zircon were investigated by TGA and XRD.The results show that:(1)carbon source is an important factor for a rapid reaction,and activated carbon is chosen as the carbon source considering the expect products and reaction rate;(2)reaction temperature has vital effect on reaction rate and product.In case of carbon content above 20%,the zircon phase and m-ZrO2 phase decrease with increasing temperature,while the Zr7N8O4 phase increases firstly and then decreases,and the ZrN phase increases continually;(3)different carbon contents result in different reaction products.The higher the carbon content,the lower the starting temperature for the CRN of zircon. | YU Renhong FU Yadong ZHANG Mengmeng WANG Lizhi HONG Quanquan ZHANG Ruohua | 2011 | China's Refractories2011，20，1： | 3 |
| 3 | Serum ficolin-2 concentrations are significantly changed in patients with hepatitis B virus infection and liver diseases显示文摘Human ficolin-2 is an important lectin complement pathway activator that is secreted from liver cells and has been implicated as an anti-infection innate immune molecule. However, the role of ficolin-2 protein and its dynamic changes over the course of and in the prognosis of chronic hepatitis B(CHB) and hepatocellular carcinoma(HCC) remain unclear. In this study, we analyzed ficolin-2 protein expression in a cohort of individuals with CHB infection, HCC and cirrhosis. A sandwich enzyme-linked immunosorbent assay(ELISA) method was used to measure serum ficolin-2 concentrations. Ficolin-2 expression in liver tissues was detected by immunohistochemical staining. Serum ficolin-2 concentrations in CHB patients were significantly higher than in healthy controls and HBV carriers. After 48 weeks of routine amelioration liver function treatment, serum ficolin-2 concentrations decreased and were positively correlated with favorable alanine aminotransferase(ALT), HBV DNA and HBe Ag-seroconversion outcomes. Interestingly, we observed much lower expression of serum and intrahepatic ficolin-2 in HCC and cirrhosis compared with healthy controls. Our findings suggest that serum and intrahepatic ficolin-2 levels may be considered one of the indicators for the response of chronic HBV infection, HCC and cirrhosis. | Tielong Chen Yilan Hu Quanquan Ding Jing Yu Fubing Wang Fengling Luo Xiao-Lian Zhang | 2015 | Virologica Sinica2015，30，4： | 2 |
| 4 | Linking key intervention timings to rapid declining effective reproduction number to quantify lessons against COVID-19显示文摘Coronavirus disease 2019(COVID-19)is currently under a global pandemic trend.The efficiency of containment measures and epidemic tendency of typical countries should be assessed.In this study,the efficiency of prevention and control measures in China,Italy,Iran,South Korea,and Japan was assessed,and the COVID-19 epidemic tendency among these countries was compared.Results showed that the effective reproduction number(Re)in Wuhan,China increased almost exponentially,reaching a maximum of 3.98 before a lockdown and rapidly decreased to below 1 due to containment and mitigation strategies of the Chinese government.The Re in Italy declined at a slower pace than that in China after the implementation of prevention and control measures.The Re in Iran showed a certain decline after the establishment of a national epidemic control command,and an evident stationary phase occurred because the best window period for the prevention and control of the epidemic was missed.The epidemic in Japan and South Korea reoccurred several times with the Re fluctuating greatly.The epidemic has hardly rebounded in China due to the implementation of prevention and control strategies and the effective enforcement of policies.Other countries suffering from the epidemic could learn from the Chinese experience in containing COVID-19. | Zhihang Peng Wenyu Song Zhongxing Ding Quanquan Guan Xu Yang Qiaoqiao Xu Xu Wang Yankai Xia | 2020 | Frontiers of Medicine2020，14，5： | 2 |
| 5 | A cross-layertransmission scheduling scheme for wireless sensor networks显示文摘 | Liang Quanquan Yuan Dongfeng Wang Yong | 2007 | Computer Communications2007，132，29： | 1 |
| 6 | MiR-20a Induces Cell Radioresistance by Activating the PTEN/PI3K/Akt Signaling Pathway in Hepatocellular Carcinoma显示文摘 | Yuqin Zhang Lin Zheng Yi Ding Qi Li Rong Wang Tongxin Liu Quanquan Sun Hua Yang Shunli Peng Wei Wang Longhua Chen | 2015 | International Journal of Radiation Oncology, Biol2015，，5： | 1 |
| 7 | Pd-Catalyzed Ortho-Directed C-H Glycosylation of Arenes Using N-linked Bidentate Auxiliaries显示文摘Main observation and conclusion A set of Pd-catalyzed ortho-directed C-H glycosylation reactions with glycosyl chloride donors using various N-linked bidentate auxil-iaries has been developed for synthesis of C-aryglycosides.A broad range of pyranose and furanose moieties can be installed on the ortho position of arylamine,carbazole,indole and benzylamine type substrates in high yield and with high regio-and diastereoselec-tivity.These auxiliaries can be readily installed and removed under relatively mild conditions. | Quanquan Wang Wanjun Zhu Qikai Sun Gang He Gong Chen | 2021 | Chinese Journal of Chemistry2021，39，3： | 1 |
| 8 | A cross-layer transmission scheduling scheme for wireless sensor networks显示文摘 | Liang Quanquan Yuan Dongfeng Wang Yong | 2007 | Computer Communications2007，132，30： | 1 |
| 9 | A fundamental principle and systematic procedures for process intensification in reactive distillation columns显示文摘 | Kejin Huang Quanquan Lin Huan Shao Chao Wang Shaofeng Wang | 2010 | Chemical Engineering & Processing: Process Intensification2010，，3： | 1 |
| 10 | Enhanced room-temperature Naþionic conductivity in Na_(4.92)Y_(0.92)Zr_(0.08)Si_(4)O_(12)显示文摘Developing cost-effective and reliable solid-state sodium batteries with superior performance is crucial for stationary energy storage.A key component in facilitating their application is a solid-state electrolyte with high conductivity and stability.Herein,we employed aliovalent cation substitution to enhance ionic conductivity while preserving the crystal structure.Optimized substitution of Y^(3+)with Zr^(4+)in Na_(5)YSi_(4)O_(12) introduced Naþion vacancies,resulting in high bulk and total conductivities of up to 6.5 and 3.3 mS cm^(-1),respectively,at room temperature with the composition Na_(4.92)Y_(0.92)Zr_(0.08)Si_(4)O_(12)(NYZS).NYZS shows exceptional electrochemical stability(up to 10 V vs.Naþ/Na),favorable interfacial compatibility with Na,and an excellent critical current density of 2.4 mA cm^(-2).The enhanced conductivity of Naþions in NYZS was elucidated using solid-state nuclear magnetic resonance techniques and theoretical simulations,revealing two migration routes facilitated by the synergistic effect of increased Naþion vacancies and improved chemical environment due to Zr^(4+)substitution.NYZS extends the list of suitable solid-state electrolytes and enables the facile synthesis of stable,low-cost Naþion silicate electrolytes. | Aikai Yang Kai Yao Mareen Schaller Enkhtsetseg Dashjav Hang Li Shuo Zhao Qiu Zhang Martin Etter Xingchen Shen Huimin Song Qiongqiong Lu Ruijie Ye Igor Moudrakovski Quanquan Pang Sylvio Indris Xingchao Wang Qianli Ma Frank Tietz Jun Chen Olivier Guillon | 2023 | eScience2023，3，6： | 0 |
| 11 | Synthesis of 2-Deoxy-C-Glycosides via Iridium-Catalyzed sp^(2)and sp^(3)C-H Glycosylation with Unfunctionalized Glycals显示文摘A new protocol for the synthesis of 2-deoxy-C-aryl-glycosides and 2-deoxy-C-alkyl-glycosides via iridium-catalyzed directed C—H glycosylation with glycals is reported.The method is amenable for both the C_(2)C—H glycosylation of indoles and the methyl C—H glycosylation of secondary methyl amines under the control of an N-linked benzoxazole directing group.The benzoxazole group can be cleanly removed by the treatment of KOH or LiAlH_(4). | Wanjun Zhu Qikai Sun Hai Chang Hui-Xing Zhang Quanquan Wang Gong Chen Gang He | 2022 | Chinese Journal of Chemistry2022，40，5： | 0 |
| 12 | A NIR fluorescent probe for imaging thiophenol in the living system and revealing thiophenol-induced oxidative stress显示文摘Thiophenol(PhSH)is an important raw material for organic synthesis,while its high toxicity to organisms makes it an environmental pollutant.Therefore,it is crucial to accurately detect PhSH and explore its metabolic process in the living system.Herein,a near-infrared(NIR)fluorescent probe TEM-FB was developed for sensing PhSH with a turn-on fluorescent signal at 719nm and a large Stokes shift(198 nm)based on generating the intramolecular charge transfer(ICT)process.TEM-FB shows high specificity and significant sensitivity towards PhSH(detection limit:10 nmol/L)via the aromatic nucleophilic substitution mechanism.Furthermore,it was successfully applied to image PhSH in multiple cell lines and in zebrafish.Notably,we revealed the oxidative stress process caused by PhSH and demonstrated that the hydrogen peroxide(H_(2)O_(2))in cells would alleviate the poisonousness from exogenous PhSH for the first time.This work provides a promising bioimaging tool for monitoring PhSH in living systems and visualizing the process of oxidative stress induced by PhSH. | Zesi Wang Jiao Li Jiao Chen Zifeng Cao Hui Li Yaopeng Cao Quanquan Li Mengyao She Ping Liu Shengyong Zhang Jianli Li | 2023 | Chinese Chemical Letters2023，34，8： | 0 |
| 13 | Feasibility of Haze Governance Based on Carbon Sink Mode显示文摘In recent years,there are research findings of haze formation in various fields of academic circle. It has proved that causes of haze take on diverse characteristics. Thus,from both the natural and human perspective,haze governance should be diverse. Research conclusions on causes of haze formation mainly focus on special geographical structure,and meteorological factors such as relatively stable atmosphere,high rate of calm wind,high relative humidity and temperature of air,and human factors such as industrial pollution,automotive exhaust emissions,aerosol pollution,eutrophication of soil water,and change of city underlying surface. Carbon sink mode is a new channel for haze governance.In carbon sink mode,it is feasible to regulate relative humidity and temperature in air,enhance global wind,and reduce fine particles and microorganisms of air pollution,so as to reduce haze pollution. Besides,China's special potential of carbon sink market makes it possible to govern haze on the base of carbon sink. | Jie HE Quanquan WANG | 2015 | Asian Agricultural Research2015，7，9： | 0 |
| 14 | Total Synthesis of C-α-Mannosyl Tryptophan via Palladium-Catalyzed C-H Glycosylation显示文摘The C2-α-mannosyl-tryptophan amino acid is produced by a unique posttranslational modification(PTM)of proteins and poses a significant synthetic challenge.A new strategy based on Pd-catalyzed auxiliary-directed remote C-H glycosylation of tryptophan was developed,which generates the C2-α-mannopyranose(Man)-Trp unit in a highly efficient and stereoselective fashion.Density functional theory(DFT)computational studies support a concerted oxidative addition mechanism for the stereospecific functionalization of a Pd(II)palladacycle intermediate with anα-mannosyl chloride donor.The utility of this method was demonstrated in the first total synthesis of insect C-glycopeptide hormone Cam-HrTH-I. | Quanquan Wang Yue Fu Wanjun Zhu Shuang An Qianyi Zhou Shou-Fei Zhu Gang He Peng Liu Gong Chen | 2021 | CCS Chemistry2021，3，6： | 0 |
| 15 | Oscillation-specific nodal alterations in early to middle stages Parkinson’s disease显示文摘Background:Different oscillations of brain networks could carry different dimensions of brain integration.We aimed to investigate oscillation-specific nodal alterations in patients with Parkinson’s disease(PD)across early stage to middle stage by using graph theory-based analysis.Methods:Eighty-eight PD patients including 39 PD patients in the early stage(EPD)and 49 patients in the middle stage(MPD)and 36 controls were recruited in the present study.Graph theory-based network analyses from three oscillation frequencies(slow-5:0.01–0.027 Hz;slow-4:0.027–0.073 Hz;slow-3:0.073–0.198 Hz)were analyzed.Nodal metrics(e.g.nodal degree centrality,betweenness centrality and nodal efficiency)were calculated.Results:Our results showed that(1)a divergent effect of oscillation frequencies on nodal metrics,especially on nodal degree centrality and nodal efficiency,that the anteroventral neocortex and subcortex had high nodal metrics within low oscillation frequencies while the posterolateral neocortex had high values within the relative high oscillation frequency was observed,which visually showed that network was perturbed in PD;(2)PD patients in early stage relatively preserved nodal properties while MPD patients showed widespread abnormalities,which was consistently detected within all three oscillation frequencies;(3)the involvement of basal ganglia could be specifically observed within slow-5 oscillation frequency in MPD patients;(4)logistic regression and receiver operating characteristic curve analyses demonstrated that some of those oscillation-specific nodal alterations had the ability to well discriminate PD patients from controls or MPD from EPD patients at the individual level;(5)occipital disruption within high frequency(slow-3)made a significant influence on motor impairment which was dominated by akinesia and rigidity.Conclusions:Coupling various oscillations could provide potentially useful information for large-scale network and progressive oscillation-specific nodal alterations were observed in PD patients across early to middle stages. | Xiaojun Guan Tao Guo Qiaoling Zeng Jiaqiu Wang Cheng Zhou Chunlei Liu Hongjiang Wei Yuyao Zhang Min Xuan Quanquan Gu Xiaojun Xu Peiyu Huang Jiali Pu Baorong Zhang Min-Ming Zhang | 2019 | Translational Neurodegeneration2019，8，1： | 0 |
| 16 | Design of the Rotation Angle Measurement System for the Atmospheric Dispersion Corrector (ADC)显示文摘In order to measure the rotation angle error of the worm and gear mechanisms in the atmospheric dispersion corrector( ADC),a novel measurement system based on the autocollimator is designed in this paper.Based on the position relations between the shaft and spot converged by rays of autocollimator,the rotation angle can be calculated quickly and conveniently using a brief algorithm. An optical wedge is introduced to the measurement system for suppressing the awful measuring error caused by the axial wobbly error. The measurement system can measure the shaft rotation angle at any rotation position,which is the novel usage of the two-dimensional autocollimator. Its optical layout is very simple. Only an optical wedge and two plane mirrors are needed besides the autocollimator. The measurement accuracy of the proposed method is less than±0.5 arcmin. In the measurement of two worms and gears mechanisms in ADC,the rotation angle error are±0.05° and ±0.07° respectively,which all satisfies the design demand( ±0.1°). The proposed measurement system can be also suits for some engineering fields. | Wenjie Li Quanquan Mu Shaoxin Wang Chengliang Yang Haiping Wang Zhaoliang Cao Li Xuan | 2017 | Journal of Harbin Institute of Technology(New Series)2017，24，4： | 0 |
| 17 | Palladium-Catalyzed O- and N-Glycosylation with Glycosyl Chlorides显示文摘Despite the significant progress in carbohydrate chemistry,there remains a pressing need for efficient and practical glycosylationmethods using simple glycosyl donors and with high atom economy.Herein,a new protocol for glycosylation with glycosyl chloride donors under palladium-catalyzed conditions is developed.PdII complex serves as a Lewis acid to promote the activation of glycosyl chloride for the formation of oxocarbeniumion intermediate.This new method is operationally simple,robust,and enables efficient synthesis of both O-and N-glycosides with a broad substrate scope.In particular,it offers an easy access to a range of N-ribonucleoside analogs. | Shuang An Quanquan Wang Wanjun Zhu Qikai Sun Gang He Gong Chen | 2021 | CCS Chemistry2021，3，7： | 0 |
| 18 | Robust chromophore-integrated MOFs as highly visible-white-light active and tunable size-selective photocatalysts towards benzothiazoles显示文摘Visible-light heterogeneous photocatalyst with high activity and selectivity is crucial for the development of organic transformations, but remains a formidable challenge. Herein, a simple and effective strategy was developed to integrate tetrazine moiety, a visible light active unit, into robust metal-organic frameworks(2D MOF-1(M), M = Co, Mn, Zn, and 3D MOF-2(Co)). MOF-1 series are isomorphous 2D porous frameworks, and MOF-2(Co) displays 3D porous framework. Interestingly, benefiting from the oxidative active species of O_(2)·-, these MOFs all exhibit obviously highly enhanced photocatalytic activities toward the straightforward condensation of o-aminothiophenol and aromatic aldehydes at room temperature in Et OH under visible-white-light irradiation. Notably, compared to 3D MOF, the 2D layered MOF-1(Co) exhibited more excellent catalytic activity with a wide range of substrates possessing preeminent tolerance of steric hindrance. Most impressively, MOF-1(Co) can be recycled at least five times without significant loss of catalytic activity or crystallinity, exhibiting excellent stability and reusability. This study sheds light on the wide-ranging prospects of visible light active 2D MOFs as green photocatalysts for the preparation of fine chemicals. | Hua Liu Quanquan Li Penghui Pan Li Zhou Bing Deng Shuya Zhao Ping Liu Yaoyu Wang Jianli Li | 2023 | Chinese Chemical Letters2023，34，10： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员