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| 1 | Anterior resection for rectal carcinoma-risk factors for anastomotic leaks and strictures显示文摘AIM:To determine the incidence and factors responsible for anastomotic leaks and stricture following anterior resection(AR)and its subsequent management.METHODS:Retrospective analysis of data from 108 patients with rectal carcinoma who underwent AR or low anterior resection(LAR)to identify the various preoperative,operative,and post operative factors that might have influence on anastomotic leaks and strictures.RESULTS:There were 68 males and 40 females with an average of 47 years(range 21-75 years).The median distance of the tumor from the anal verge was 8 cm(range 3-15 cm).Sixty(55.6%)patients underwent handsewn anastomosis and 48(44.4%)were stapled.The median operating time was 3.5 h(range2.0-7.5 h).Sixteen(14.6%)patients had an anastomotic leak.Among these,11 patients required reexploration and five were managed expectantly.The anastomotic leak rate was similar in patients with and without diverting stoma(8/60,13.4%with stoma and 8/48;16.7%without stoma).In 15(13.9%)patients,resection margins were positive for malignancy.Ninteen(17.6%)patients developed anastomotic strictures at a median duration of 8 mo(range 3-20 mo).Among these,15 patients were successfully managed with per-anal dilatation.On multivariate analysis,advance age(>60 years)was the only risk factor for anastomotic leak(P=0.004).On the other hand,anastomotic leak(P=0.00),mucin positive tumor(P =0.021),and lower rectal growth(P=0.011)were found as risk factors for the development of an anastomotic stricture.CONCLUSION:Advance age is a risk factor for an anastomotic leak.An anastomotic leak,a mucin-secreting tumor,and lower rectal growth predispose patients to develop anastomotic strictures. | Ashok Kumar Ram Daga Paari Vijayaragavan Anand Prakash Rajneesh Kumar Singh Anu Behari Vinay K Kapoor Rajan Saxena | 2011 | World Journal of Gastroenterology2011，17，11： | 28 |
| 2 | Pseudoaneurysm of profunda femoris artery following dynamic hip screw fixation for intertrochanteric femoral fracture显示文摘动态新潮的螺丝钉固定是为 intertrochanteric 的内部固定的一个通常执行的过程大腿骨的破裂。跟随起作用的固定的动脉的损害是一个稀罕却严肃的事件。我们在场与一个动态新潮的螺丝钉在 intertrochanteric 骨折的内部固定以后开发了 profunda femoris 动脉的 pseudoaneurysm 的一个病人。诊断被 angiographic 学习证实,它被卷 embolization 成功地对待。 | Shailendra Singh Sumit Arora Ankit Thora Ram Mohan, Sumit Sural Anti Dhal | 2013 | Chinese Journal of Traumatology2013，16，4： | 13 |
| 3 | A review on synthesis of graphene,h-BN and MoS2 for energy storage applications:Recent progress and perspectives显示文摘The significance of graphene and its two-dimensional(2D)analogous inorganic layered materials especially as hexagonal boron nitride(h-BN)and molybdenum disulphide(MoS2)for“clean energy”applications became apparent over the last few years due to their extraordinary properties.In this review article we study the current progress and selected challenges in the syntheses of graphene,h-BN and MoS2 including energy storage applications as supercapacitors and batteries.Various substrates/catalysts(metals/insulator/semiconducting)have been used to obtain graphene,h-BN and MoS2 using different kinds of precursors.The most widespread methods for synthesis of graphene,h-BN and MoS2 layers are chemical vapor deposition(CVD),plasma-enhanced CVD,hydro/solvothermal methods,liquid phase exfoliation,physical methods etc.Current research has shown that graphene,h-BN and MoS2 layered materials modified with metal oxide can have an insightful influence on the performance of energy storage devices as supercapacitors and batteries.This review article also contains the discussion on the opportunities and perspectives of these materials(graphene,h-BN and MoS2)in the energy storage fields.We expect that this witen review article including recent research on energy storage will help in generating new insights for further development and practical applications of graphene,h-BN and MoS2 layers based materials. | Rajesh Kumar Sumanta Sahoo Ednan Joanni Rajesh Kumar Singh Ram Manohar Yadav Rajiv Kumar Verma Dinesh Pratap Singh Wai Kian Tan Angel Perez del Pino Stanislav A.Moshkalev Atsunori Matsuda | 2019 | Nano Research2019，12，11： | 12 |
| 4 | JAK/STAT signaling regulates tissue outgrowth and male germline stem cell fate in Drosophila显示文摘In multicellular organisms, biological activities are regulated by cell signaling. The various signal transduction path- ways regulate cell fate, proliferation, migration, and polarity. Miscoordination of the communicative signals will lead to disasters like cancer and other fatal diseases. The JAK/STAT signal transduction pathway is one of the pathways, which was first identified in vertebrates and is highly conserved throughout evolution. Studying the JAK/STAT signal transduc- tion pathway in Drosophila provides an excellent opportunity to understand the molecular mechanism of the cell regu- lation during development and tumor formation. In this review, we discuss the general overview of JAK/STAT signaling in Drosophila with respect to its functions in the eye development and stem cell fate determination. | Shree Ram SINGH Steven X. HOU | 2005 | Cell Research2005，15，1： | 9 |
| 5 | Community Responses to Mountain Tourism:A Case in Bhyundar Valley,Indian Himalaya显示文摘Tourism industry has become an important part of Indian economy,and tourism development has been,however,concentrated to a few areas. Accumulation of tourism activities has reached the critical stage in most of the tourism centers,which pose serious threats to the natural environment. The Bhyundar Valley of Nanda Devi Biosphere Reserve (NDBR) in Uttarakhand State of the Indian Himalaya is a burning example of such problems. Land use/cover changes,deforestation and accumulation of garbage are some of the negative impacts of unregulated tourism in the valley. Unsustainable activities of tourists and villagers in the valley make such problems very severe. To deal with the ongoing problems and ensure community involvement in tourism management and environmental conservation,the Biosphere Reserve Authority introduced ecotourism in the form of Eco Development Committees (EDCs) in the Bhyundar Valley. Study reveals that many problems associated with tourism have been minimized to some extent with the help of EDCs but few are still prevailing in valley. However,the existing attempts to conserve the valley from the negative effects of tourism are inadequate and modifications are needed in the current initiatives. | Ram Babu Singh Suraj Mal Chandra Prakash Kala | 2009 | Journal of Mountain Science2009，6，4： | 6 |
| 6 | Discrete element method study of shear-driven granular segregation in a slowly rotating horizontal drum显示文摘 | Ram Chand Sithi V. Muniandy Chiow San Wong Jasbir Singh | 2017 | Particuology2017，15，3： | 4 |
| 7 | Analysing the relationship between drought and soil erosion using vegetation health index and RUSLE models in Godavari middle sub-basin,India显示文摘Drought is a natural phenomenon posing severe implications for soil,groundwater and agricultural yield.It has been recognized as one of the most pervasive global change drivers to affect the soil.Soil being a weakly renewable resource takes a long time to form,but it takes no time to degrade.However,the response of soil to drought conditions as soil loss is not manifested in the existing literature.Thus,this study makes a concerted effort to analyze the relationship between drought conditions and soil erosion in the middle sub-basin of the Godavari River in India.MODIS remote sensing data was utilized for driving drought indices during 2000-2019.Firstly,we constricted Temperature condition index(TCI)and Vegetation Condition Index(VCI)from Land Surface Temperature(LST)and Enhanced Vegetation Index(EVI)derived from MODIS data.TCI and VCI were then integrated to determine the Vegetation Health Index(VHI).Revised Universal Soil Loss Equation(RUSLE)was utilized for estimating soil loss.The relationship between drought condition and vegetation was ascertained using the Pearson correlation.Most of the northern and southern watersheds experienced severe drought condition in the sub-basin during2000-2019.The mean frequency of the drought occurrence was 7.95 months.The average soil erosion in the sub-basin was estimated to be 9.88 t ha^(-1)year^(-1).A positive relationship was observed between drought indices and soil erosion values(r value being 0.35).However,wide variations were observed in the distribution of spatial correlation.Among various factors,the slope length and steepness were found to be the main drivers of soil erosion in the sub-basin.Thus,the study calls for policy measures to lessen the impact of drought and soil erosion. | Md Masroor Haroon Sajjad Sufia Rehman Roshani Singh Md Hibjur Rahaman Mehebub Sahana Raihan Ahmed Ram Avtar | 2022 | Geoscience Frontiers2022，13，2： | 4 |
| 8 | Graphene-based bipolar plates for polymer electrolyte membrane fuel cells显示文摘Bipolar plates(BPs)are a major component of polymer electrolyte membrane fuel cells(PEMFCs).BPs play a multifunctional character within a PEMFC stack.It is one of the most costly and critical part of the fuel cell,and hence the development of efficient and cost-effective BPs is of much interest for the fabrication of next-generation PEMFCs in future.Owing to high electrical conductivity and chemical inertness,graphene is an ideal candidate to be utilized in BPs.This paper reviews recent advances in the area of graphene-based BPs for PEMFC applications.Various aspects including the momentous functions of BPs in the PEMFC,favorable features of graphene.based BPs,performance evaluation of various reported BPs with their advantages and disadvantages,challenges at commercial level products and future prospects of frontier research in this direction are extensively documented. | Ram Sevak SINGH(El) Anurag GAUTAM Varun RAI | 2019 | Frontiers of Materials Science2019，13，3： | 3 |
| 9 | 自然杀伤T细胞活化对狼疮鼠(NZB×NZW)F1的影响显示文摘目的探讨自然杀伤(NK)T细胞活化剂α-脑苷酯(α-galactosylceramide,α-GalCer)对狼疮鼠(NZB×NZW)F1小鼠(BWF1)的影响。方法40只BWF1按治疗开始时鼠龄分为5周组和6月组。每组又分治疗组和对照组,分别腹腔内注射α-GalCer和溶媒(vehicle),测定蛋白尿并记录生存时间,治疗前及治疗后每月取血检测IgG型抗ds-DNA抗体、抗心磷脂抗体(ACL)和类风湿因子(RF)。另有10只BWF1小鼠分两组,分别静脉注射α-GalCer和溶媒,2h后取血检测白细胞介素(IL)-2、IL-4、IL-10和干扰素(IFN)-酌。结果静脉注射α-GalCer后BWF1鼠血清Th1细胞因子IL-2、IFN-酌增加,Th2细胞因子IL-4、IL-10减少。治疗组BWF1鼠IgG型抗ds-DNA抗体、RF水平较对照组低。治疗和对照组严重蛋白尿发生率及生存率差异无统计学意义。结论α-GalCer可以活化NKT细胞,降低某些自身抗体水平,但不足以改善蛋白尿和生存率。 | 汪国生 YANG Junqi SINGH Ram Raj | 2005 | 中华风湿病学杂志2005，9，11： | 3 |
| 10 | 两种草蛉对取食棉花的扶桑绵粉蚧的嗅觉反应(英文)显示文摘捕食性的普通草蛉Chrysoperla sp.(carnea group)和安平草蛉Mallada desjardinsi(Navas)(脉翅目:草蛉科)的寄主-生境定位取决于其觅食行为以及对各阶段释放的植物气味的行为反应。本研究调查了这两种交配的草蛉成虫以及取食棉花的扶桑绵粉蚧Phenacoccus solenopsis的反应,以便了解它们之间的三重营养关系。结果表明:草蛉雄虫和雌虫均能感受到棉花植株释放的绿叶挥发物;植株的各个阶段均可使捕食性昆虫和绵粉蚧定位。在受绵粉蚧为害的棉叶上饱和烃含量高,说明草蛉成虫的反应更为强烈;在植株受为害期和开花期释放捕食性昆虫,可提高田间捕食性昆虫的作用。这些结果提示有效的生物防治取决于捕食性昆虫在植株上的天然定殖能力以及对害虫的吞食能力。 | Sudhida GAUTAM Ashok Kumar SINGH Ram Dass GAUTAM | 2010 | 昆虫学报2010，53，5： | 3 |
| 11 | Discovery and preclinical development of ⅢM-160, a Bergenia ciliatabased anti-inflammatory and anti-arthritic botanical drug candidate显示文摘Objective: Bergenia ciliata(Haw.) Sternb. is used in the Indian traditional system of medicine to treat various ailments including rheumatism and to heal wounds. The objective of the present study was to perform a preclinical characterization of the B. ciliata-based botanical extract IIIM-160.Methods: ⅢM-160 was chemically standardized and analyzed for heavy metal content, aflatoxins,pesticides and microbial load. The in vitro and in vivo efficacies were determined in suitable models of inflammation, arthritis and nociception. An acute oral toxicity study was performed in Swiss albino mice.A suitable oral formulation was developed and characterized.Results: Bergenin was found to be the major component(9.1% w/w) of ⅢM-160. The botanical lead displayed inhibition of lipopolysaccharide-induced production of proinflammatory cytokines in THP-1 cells, with selectivity toward interleukin-6(IL-6) and had an excellent safety-window. It showed anti-inflammatory, anti-arthritic and antinociceptive activity in animal models and was not toxic at oral doses up to 2 g/kg in Swiss-albino mice. The gastroretentive, sustained-release capsule formulation showed sustained-release of the bergenin over the period of 24 h, resulting in improved plasma-exposure of bergenin in Sprague–Dawley rats.Conclusion: The dual-activity of IL-6 inhibition and antinociception marks the suitability of ⅢM-160 for treating rheumatoid arthritis. This study will serve as the benchmark for further research on this botanical formulation. | Sandip B.Bharate Vikas Kumar Sonali S.Bharate Bikarma Singh Gurdarshan Singh Amarinder Singh Mehak Gupta Deepika Singh Ajay Kumar Surjeet Singh Ram A.Vishwakarma | 2019 | Journal of Integrative Medicine2019，17，3： | 3 |
| 12 | Effects of rainwater harvesting on herbage diversity and productivity in degraded Aravalli hills in western India显示文摘Over-exploitation and rural growth have severely damaged native vegetations of Aravalli hills in Rajasthan, India. This study was conducted to evaluate the effects of different restoration practices (i.e., rainwater harvesting (RWH) and planting of tree seedlings) on improve- ment in soil water and nutrients and growth and biomass of herbaceous vegetation. Contour trench (CT), Gradonie (G), Box trench (BT), V-ditch (VD) and a control were imposed on 75 plots (each of 700 m 2 ) in natural slope gradient defined as <10%, 10% 20% and >20% slopes in 2005. Each plot had three micro-sites of 1-m 2 at up (USP), middle (MSP) and lower (LSP) part of the plot for observation in 2008. The existed gradient (due to soil texture and topographic features) of soil pH, EC, SOC, NH 4 - N, NO 3 -N and PO 4 -P in June 2005 between >20% to <10% slopes were decreased in 2008 after applying RWH techniques. Such improvement in soil status promoted vegetation growth and biomass in higher slope gra- dients. Soil water, species diversity and herbage biomass increased from USP to LSP, and RWH techniques had positive role in improving SOC, nutrients, vegetation population, evenness and growth at MSP. Despite of lowest SWC, regular rain and greater soil water usage enhanced green and dry herbage biomasses in 10% 20% and >20% slopes, compared with <10% slope. The highest diversity in CT treatment was related to herbage biomass, which was enhanced further by highest concentrations of SOC and PO 4 -P. Further, CT treatment was found to be the best treat- ment in minimizing biomass variance in different slopes. Conclusively, soil texture and topographic features controlled soil water and nutrients availability. Rainwater harvesting techniques increased soil water storage and nutrient retention and also enhanced vegetation status and biomass by minimizing the effects of hillslopes. Thus depending upon the site conditions, suitable RWH technique could be adopted to increase herb- age biomass while rehabilitating the degraded hills. | G. Singh G.R. Choadhary B. Ram N.K. Limba | 2011 | Journal of Forestry Research2011，22，3： | 3 |
| 13 | Adaptive Cell Segmentation and Tracking for Volumetric Confocal Microscopy Images of a Developing Plant Meristem显示文摘自动化分割并且在活跃地开发纸巾房间追踪能提供房间行为的一个范围的高产量、量的空间与时间的大小;导致形态发生的内在的动力学的更好的理解的房间扩大和房间部门动力学。这里,我们学习了在用扫描显微镜学(CLSM ) 的共焦的激光获得的微速摄影的容量的图象栈构造房间系的问题。工作的新奇贡献躺在它在浓密地包装的织物分割并且追踪房间的能力,射击顶端的分裂组织(SAM ) 通过靠近环的、适应分割的使用,并且追踪来临。追踪的产量充当分割的质量的指示物并且接着,分割能被改进获得更好的追踪结果。我们构造最小化分割错误的优化功能,接着,它从追踪的结果被估计。这条适应途径显著地改善追踪并且分割什么时候与分割和追踪的模块独立在操作的一个开的环框架相比。 | Min Liu Anirban Chakrabortyt Damanpreet Singh Ram Kishor Yadav Gopi Meenakshisundaram G. Venugopala Reddy Amit Roy-Chowdhury | 2011 | Molecular Plant2011，4，5： | 2 |
| 14 | Gastric cancer stem cells: A novel therapeutic target显示文摘 | Shree Ram Singh | 2013 | Cancer Letters2013，，： | 2 |
| 15 | 针对稳定和不稳定二阶时滞过程的IMC-PID控制器的性能改进设计(英文)显示文摘针对不稳定二阶时滞系统,提出了一种具有逆响应(RHP零)特性的IMC-PID控制器。通过Ms和λ图计算合适的调优参数λ,使性能和鲁棒性之间达到平衡。从文献中选取了六种不同形式的过程模型,说明了该方法的适用性。通过ITAE和总变差TV计算控制器的性能,并与最近发布的调优规则进行比较。通过使用设置点加权参数来消除不必要的超调。通过对各模型参数进行摄动,验证了控制器的鲁棒性。闭环控制结果表明,所设计的控制器在模型不确定性条件下具有较强的鲁棒性。与其他最近报道的方法相比,该方法具有更好的闭环响应。 | Munna KUMAR Durga PRASAD Ram Sharan SINGH | 2020 | Journal of Central South University2020，27，1： | 2 |
| 16 | Microstructural evolution of die-cast and homogenized AZ91 Mg-alloys during dry sliding condition显示文摘Received 16 July 2016;revised 24 January 2017;accepted 7 February 2017 Available online 22 February 2017 Abstract Microstructural evolution of die-cast and homogenized AZ91 Mg-alloys was investigated during dry sliding wear condition.Tribological tests were performed using a pin-on-disc(EN8 steel)configuration with a normal load of 50 N at a constant sliding speed of 2.5 ms^(−1) under ambient environment.Delamination was recognized as a predominant wear mechanism in both of these materials.The die-cast AZ91 Mg-alloy exhibits lower coefficient of friction and higher wear rate.This can be ascribed to increase in the intensity of load bearing capacity of hardβ-Mg_(17)Al_(12) phase,and crack formation/de-cohesion at the interface between primaryα-Mg and discontinuousβ-Mg_(17)Al_(12) phases.On the contrary,the homogenized AZ91 Mg-alloy experiences higher coefficient of friction and lower wear rate.The friction-induced microstructural evolution(supersaturatedα-Mg to eutectic(α+β-Mg_(17)Al_(12)))tending to minimize the wear rate by providing barrier to material removal in the near surface region of homogenized AZ91 Mg-alloy.Therefore,experimental observation revealed that an inverse relationship exists between wear rate and coefficient of friction for the investigated materials.The analysis of worn surfaces and subsurfaces by electron microscopy provided evidence to delamination wear and microstructural evolution. | Nagaraj M.Chelliah Ram Kumar Harpreet Singh M.K.Surappa | 2017 | Journal of Magnesium and Alloys2017，5，1： | 2 |
| 17 | Rapid screening and distribution of bioactive compounds in different parts of Berberis petiolaris using direct analysis in real time mass spectrometry显示文摘Berberis petiolaris Wall,ex G.Don,an unexplored medicinal plant belonging to the family Berberidaceae,is a large deciduous shrub found in Western Himalaya between 1800-3000 m.Chemical profiling of fruit,leaf,root and stem was done by direct analysis in real time mass spectrometry followed by multivariate analysis for discrimination among the plant parts.The bioactive compounds,including magnoflorine,berberine,jatrorrhizine,thalifendine/berberrubine,demethyleneberberine,reticuline,8-oxoberberine,N-methyltetrahydroberberine,tetrahydropalmatine,tetrahydroberberine and palmatine,were identified by their exact mass measurement and the corresponding molecular formula of each compound.A comparative study of distribution pattern for all these bioactive alkaloids showed qualitative and quantitative variations in different parts of B.petiolaris.Principal component analysis clearly discriminated each part of B.petiolaris plant. | Awantika Singh Vikas Bajpai Mukesh Srivastava Kamal Ram Arya Brijesh Kumar | 2015 | Journal of Pharmaceutical Analysis2015，5，5： | 2 |
| 18 | Patient-derived orthotopic xenograft models for cancer of unknown primary precisely distinguish chemotherapy,and tumor-targeting S.typhimurium A1-R is superior to first-line chemotherapy显示文摘Cancer of unknown primary(CUP)is a recalcitrant disease with poor prognosis because it lacks standard first-line therapy.CUP consists of diverse malignancy groups,making personalized precision therapy essential.The present study aimed to identify an effective therapy for a CUP patient using a patient-derived orthotopic xenograft(PDOX)model.This paper reports the usefulness of the PDOX model to precisely identify effective and ineffective chemotherapy and to compare the efficacy of S.typhimurium A1-R with first-line chemotherapy using the CUP PDOX model.The present study is the first to use a CUP PDOX model,which was able to precisely distinguish the chemotherapeutic course.We found that a carboplatinum(CAR)-based regimen was effective for this CUP patient.We also demonstrated that S.typhimurium A1-R was more effective against the CUP tumor than first-line chemotherapy.Our results indicate that S.typhimurium A1-R has clinical potential for CUP,a resistant disease that requires effective therapy. | Kentaro Miyake Tasuku Kiyuna Masuyo Miyake Kei Kawaguchi Sang Nam Yoon Zhiying Zhang Kentaro Igarashi Sahar Razmjooei Sintawat Wangsiricharoen Takashi Murakami Yunfeng Li Scott D.Nelson Tara A.Russell Arun S.Singh Yukihiko Hiroshima Masashi Momiyama Ryusei Matsuyama Takashi Chishima Shree Ram Singh Itaru Endo Fritz C.Eilber Robert M.Hoffman | 2018 | Signal Transduction and Targeted Therapy2018，3，1： | 2 |
| 19 | Integrals of certain univalent functions显示文摘 | Ram Singh Sunder Singh | 1979 | Pro Amer Math Soc1979，77，3： | 1 |
| 20 | Surface water of a perennial river exhibits multi-antimicrobial resistant shiga toxin and enterotoxin producing Escherichia coli显示文摘 | Ram S Vajpayee P Singh R L | 2009 | Ecotoxicology and Environmental Safety2009，72，2： | 1 |
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