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| 1 | Preliminary Scientific Results of Chang'E-1 Lunar Orbiter:Based on Payloads Detection Data in the First Phase显示文摘Chang'E-1 lunar Orbiter was launched by Long March 3A rocket from Xichang Satel-lite Launch Center at 18:05BT(Beijing Time) Oct.24,2007.It is the first step of its ambitious three-stage moon program,a new milestone in the Chinese space exploration history.The primary science objectives of Chang'E-1 lunar orbiter are to obtain three-Dimension(3D) stereo images of the lunar surface,to analyze the distribution and abundance of elements on the surface,to investigate the thickness of lunar soil,evaluate helium-3 resources and other characteristics,and to detect the space environment around the moon.To achieve the above four mission objectives,eight sets of scientific instruments are chosen as the payloads of the lunar orbiter,including a CCD stereo camera(CCD),a Sagnac-based interferometer spectrometer(ⅡM),a Laser Altimeter(LAM),a Microwave Radiometer(MRM),a Gamma-Ray Spectrometer(GRS),an X-ray spectrometer(XRS),a High-Energy Particle Detector(HPD),and two Solar Wind Ion Detectors(SWID).The detected data of the payloads show that all payloads work well.This paper introduces the status of payloads in the first phase and preliminary scientific results. | OUYANG Ziyuan JIANG Jingshan LI Chunlai SUN Huixian ZOU Yongliao LIU Jianzhong LIU Jianjun ZHAO Baochang REN Xin YANG Jianfeng ZHANG Wenxi WANG Jianyu MOU Lingli CHANG Jin ZHANG Liyan WANG Huanyu LI Yongquan ZHANG Xiaohui ZHENG Yongchun WANG Shijin BIAN Wei | 2008 | 空间科学学报2008，28，5： | 24 |
| 2 | Genome-wide comparative analysis of type-A Arabidopsis response regulator genes by overexpression studies reveals their diverse roles and regulatory mechanisms in cytokinin signaling显示文摘细胞激动素是为植物生长和开发的各种各样的方面的一个批评生长管理者。在 Arabidopsis,细胞激动素发信号被从受体播送一个信号的二部件的基于系统的 phosphorelay 调停,通过 histidine phosphotransfer 蛋白质,到下游的反应管理者(ARR ) 。这些 ARR,打字 -- A ARR 基因,其抄写能被细胞激动素很快导致,充当细胞激动素发信号的否定管理者。然而因为功能的冗余性,类型的功能 -- 在植物生长和开发的 A ARR 基因没被分析 loss-of-function 异种很好理解。在这研究,我们在所有十种类型上执行了比较功能的研究 -- 由分析这些 ARR 基因熔化了到 MYC epitope 的转基因的植物 overexpressing 的 A ARR 基因标注。ARR 基因的 Overexpression 导致许多联系细胞激动素的显型。尤其是,不同 ARR transgenes 的 overexpression 引起多样的显型,甚至在种系发生地密切相关的基因对之间,例如在 ARR3-ARR4 和 ARR5-ARR6 对以内。我们发现了 ARR 蛋白质的一个子集的累积(ARR3, ARR5, ARR7, ARR16 和 ARR17;可能 ARR8 和 ARR15 ) 被 MG132 增加,一个特定的 proteasomal 禁止者,显示这些蛋白质的那稳定性被 proteasomal 调整降级。而且,类似于的以前描绘的 ARR5, ARR6 和 ARR7, ARR16 和 ARR17 的稳定性,可能包括的 ARR8 和 ARR15,被细胞激动素调整。这些结果建议那种类型 -- A ARR 蛋白质被包含细胞激动素和 proteasome 小径的组合机制调整,从而在植物生长和开发执行特殊函数。 | Bo Ren Yan Liang Yan Deng Qingguo Chen Jian Zhang Xiaohui Yang Jianru Zuo | 2009 | Cell Research2009，19，10： | 23 |
| 3 | Multicolor Luminescent Carbon Nanoparticles: Synthesis, Supramolecular Assembly with Porphyrin, Intrinsic Peroxidase-Like Catalytic Activity and Applications显示文摘光碳 nanoparticles (CNP ) 是到 nanomaterials 的世界的新来者并且象因为他们的迷人的光致发光和潜力,是为未来 nanodevices 的有希望的积木为传统的 heavy-metals-based 量点用作无毒的代替一样处于健康和环境应用显示出大影响。此处,荧光灯 CNP 被 refluxing 与 HNO3 从蜡烛煤烟准备了并且随后由单个 centrifugation 分开了。CNP 能被实验公式 C1H0.677O0.586N0.015Na0.069 代表,并且有 20100 nm 的一种尺寸, 3.0 nm 的高度, 7.31 ns 汣癯牥的一生吗? | Xiaohui Wang Konggang Qu Bailu Xu Jinsong Ren Xiaogang Qu | 2011 | Nano Research2011，4，9： | 15 |
| 4 | Chang'E-1 Lunar Mission:An Overview and Primary Science Results显示文摘Chang'E-1 is the first lunar mission in China,which was successfully launched on Oct.24th,2007.It was guided to crash on the Moon on March 1,2009,at 52.36°E,1.50°S,in the north of Mare Fecunditatis.The total mission lasted 495 days,exceeding the designed life-span about four months.1.37Terabytes raw data was received from Chang'E-1.It was then processed into 4Terabytes science data at different levels.A series of science results have been achieved by analyzing and applicating these data,especially 'global image of the Moon of China's first lunar exploration mission'.Four scientific goals of Chang'E-1 have been achieved.It provides abundant materials for the research of lunar sciences and cosmochemistry.Meanwhile these results will serve for China's future lunar missions. | Ouyang Ziyuan Li Chunlai Lu Chang Liu Jianzhong Zou Yongliao Zhang Hongbo Jianjun Zuo Wei Su Yah Wen Weibin Bian Wei Zhao Baochang Wang Jianyu Yang Jianfeng Chang Jin Wang Huanyu Zhang Xiaohui Wang Shijin Wang Min Ren Xin Mu Lingli Kong Deqing Wang Xiaoqian Wang Fang Geng Liang Zhang Zhoubin Zheng Lei Zhu Xinying Zheng Yongchun Li Junduo Zou Xiaoduan Xu Chun Shi Shuobiao Gao Yifei Gao Guannan | 2010 | 空间科学学报2010，30，5： | 11 |
| 5 | Clinical applications of MARSALA for preimplantation genetic diagnosis of spinal muscular atrophy显示文摘Conventional PCR methods combined with linkage analysis based on short tandem repeats(STRs) or Karyomapping with single nucleotide polymorphism(SNP) arrays, have been applied to preimplantation genetic diagnosis(PGD) for spinal muscular atrophy(SMA), an autosome recessive disorder. However, it has limitations in SMA diagnosis by Karyomapping, and these methods are unable to distinguish wildtype embryos with carriers effectively. Mutated allele revealed by sequencing with aneuploidy and linkage analyses(MARSALA) is a new method allowing embryo selection by a one-step next-generation sequencing(NGS) procedure, which has been applied in PGD for both autosome dominant and X-linked diseases in our group previously. In this study, we carried out PGD based on MARSALA for two carrier families with SMA affected children. As a result, one of the couples has given birth to a healthy baby free of mutations in SMA-causing gene. It is the first time that MARSALA was applied to PGD for SMA, and we can distinguish the embryos with heterozygous deletion(carriers) from the wild-type(normal) ones accurately through this NGS-based method. In addition, direct mutation detection allows us to identify the affected embryos(homozygous deletion), which can be regarded as probands for linkage analysis, in case that the affected family member is absent. In the future, the NGS-based MARSALA method is expected to be used in PGD for all monogenetic disorders with known pathogenic gene mutation. | Yixin Ren Xu Zhi Xiaohui Zhu Jin Huang Ying Lian Rong Li Hongyan Jin Yan Zhang Wenxin Zhang Yanli Nie Yuan Wei Zhaohui Liu Donghong Song Ping Liu Jie Qiao Liying Yan | 2016 | Journal of Genetics and Genomics2016，43，9： | 9 |
| 6 | Assessment of different biomarkers provides valuable diagnostic standards in the evaluation of the risk of acute rejection显示文摘尖锐拒绝(AR ) 是为长期的拒绝在的一个强壮的风险因素肾移植接受者。AR 事件的精确、及时的诊断为疾病控制和预后是很重要的。因此,客观地评估了病人的有免疫力的地位在移植以后的治疗的地里是必要的。这纵的研究在外部血 mononuclear 房间( PBMC )和活体检视在 sera ,CD4+ T 房间的细胞内部的腺苷 triphosphate ( iATP )版本水平,和 granzyme B/perforin 表示调查了五 biomarkers ,人的白血球抗原( HLA ) -G5 和 sCD30 水平的实用性,总共肾的移植的 84 个案例的检测 AR 和 biomarkers 的决定。数据证明接受者与临床或证明的活体检视拒绝显著地增加了 CD4+ T 房间的 iATP 版本水平,并且提高了 sCD30,但是与稳定的接枝功能与个人相比在 sera 降低了 HLA-G5 水平。granzyme B 和 perforin 的表示层次也在 PBMC 和 AR 病人的接枝活体检视被提高。一起拿,我们鉴别 HLA-G5 的 sCD30, iATP, granzyme B, perforin,和 downregulation 的 upregulation 能提供珍贵诊断标准在 AR 的风险识别那些接受者。并且 iATP 可以比为预言接枝拒绝事件的其它是更好的 biomarker。 | Jin Zheng Xiaoming Ding Xiaohui Tian Zhankui Jin Xiaoming Pan Hang Yan Xinshun Feng Jun Hou Heli Xiang Li Ren Puxun Tian Wujun Xue | 2012 | Acta Biochimica et Biophysica Sinica2012，44，9： | 8 |
| 7 | Prognostic implications of epidermal growth factor receptor variant Ⅲ expression and nuclear translocation in Chinese human gliomas显示文摘Objective: To determine the prognostic implications and clinical significance of epidermal growth factor receptor variant Ⅲ(EGFRvⅢ) expression and EGFRvⅢ nuclear translocation in Chinese human gliomas.Methods: We retrospectively examined EGFRvⅢ expression and EGFRvⅢ nuclear translocation using immunohistochemistry in specimens of 240 Chinese patients with glioma, including 84 World Health Organization(WHO) II gliomas, 84 WHO Ⅲ gliomas and 72 glioblastomas(WHO IV). Factors that correlated with EGFRvⅢ and EGFRvⅢ nuclear translocation expression were analyzed by the Chi-square test. Kaplan-Meier methodology and Cox regression were used for the survival analysis.Results: Log-rank tests showed that patient age, Karnofsky performance scale(KPS) score, tumor grade,EGFRvⅢ expression, EGFRvⅢ nuclear translocation, 1 p/19 q codeletion, isocitrate dehydrogenase(IDH)mutation, Ki-67 labeling index and O6-methylguanine-DNA methyltransferase(MGMT) status(P<0.05) were significantly correlated with overall survival(OS) time. Multivariate Cox regression analysis revealed that patient age, tumor grade, EGFRvⅢ nuclear translocation, 1 p/19 q codeletion, and IDH mutation(P<0.05) were significantly correlated with OS. Patients with a high level of EGFRvⅢ nuclear translocation(≥7%) had both significantly shorter OS [hazard ratio(HR): 1.920, 95% confidence interval(95% CI): 1.228-3.003, P=0.004] and progression-free survival(PFS) times(HR: 1.661, 95% CI: 1.116-2.471, P=0.012) than those with a low level of EGFRvⅢ nuclear translocation(<7%).Conclusions: A high level of EGFRvⅢ nuclear translocation in glioma is an independent factor indicating a poor prognosis, but EGFRvⅢ expression is not an independent clinical prognostic factor. The level of EGFRvⅢ nuclear translocation maybe a novel and crucial prognostic biomarker in glioma. | Kaiyuan Yang Xiaohui Ren Liyuan Tao Peipei Wang Haihui Jiang Li Shen Yiming Zhao Yong Cui Mingxiao Li Song Lin | 2019 | Chinese Journal of Cancer Research2019，31，1： | 8 |
| 8 | A large-scale functional approach to uncover human genes and pathways in Drosophila显示文摘我们表明为他们导致 overexpression 显型的能力由 assaying 在果蝇为人的基因功能执行一幅系统的屏幕的可行性。相应于 236 人的基因的超过 1 500 根转基因的苍蝇线被建立了。总共, 51 根线能够得到建议人的基因是功能的显型。当我们发现类似的变异的显型也被主导的否定异种引起了,这些 heterologous 基因是机能上地相关的人的 ribosomal 蛋白质 L8 基因或由果蝇 RPL8 的 RNAi downregulation 的形式。显著地,果蝇 RPL8 异种能被野类型的人的 RPL8 救。我们也提供果蝇 RPL8 是表明小径的胰岛素的一个新成员的基因证据。在摘要,许多人的基因的功能出现到高度被保存,并且在果蝇识别他们的能力在 vivo 为人的抄本的大规模分析代表一个强大的基因工具。 | Rong Xu Kejing Deng Yi Zhu Yue Wu Jing Ren Min Wan Shouyuan Zhao Xiaohui Wu Min Han Yuan Zhuang Tian Xu | 2008 | Cell Research2008，18，11： | 5 |
| 9 | Comparison of viral RNA-host protein interactomes across pathogenic RNA viruses informs rapid antiviral drug discovery for SARS-CoV-2显示文摘In contrast to the extensive research about viral protein–host protein interactions that has revealed major insights about how RNA viruses engage with host cells during infection,few studies have examined interactions between host factors and viral RNAs(vRNAs).Here,we profiled vRNA–host protein interactomes for three RNA virus pathogens(SARS-CoV-2,Zika,and Ebola viruses)using ChIRP-MS.Comparative interactome analyses discovered both common and virus-specific host responses and vRNA-associated proteins that variously promote or restrict viral infection.In particular,SARS-CoV-2 binds and hijacks the host factor IGF2BP1 to stabilize vRNA and augment viral translation.Our interactome-informed drug repurposing efforts identified several FDA-approved drugs(e.g.,Cepharanthine)as broad-spectrum antivirals in cells and hACE2 transgenic mice.A co-treatment comprising Cepharanthine and Trifluoperazine was highly potent against the newly emerged SARS-CoV-2 B.1.351 variant.Thus,our study illustrates the scientific and medical discovery utility of adopting a comparative vRNA-host protein interactome perspective. | Shaojun Zhang Wenze Huang Lili Ren Xiaohui Ju Mingli Gong Jian Rao Lei Sun Pan Li Qiang Ding Jianwei Wang Qiangfeng Cliff Zhang | 2022 | Cell Research2022，32，1： | 5 |
| 10 | Introduction to the Payloads and the Initial Observation Results of Chang'E-1显示文摘Chang'E-1,the orbiter circling the moon 200km above the moon surface,is the first Chinese Lunar exploration satellite.The satellite was successfully launched on 24th October 2007.There are 8 kinds of scientific payloads onboard,including the stereo camera,the laser altimeter,the Sagnac-based interferometer image spectrometer,the Gamma ray spectrometer,the X-ray spectrom-eter,the microwave radiometer,the high energy particle detector,the solar wind plasma detector and a supporting payload data management system.Chang'E-1 opened her eyes to look at the moon and took the first batch of lunar pictures after her stereo camera was switched on in 20th November 2007.Henceforth all the instruments are successfully switched on one by one.After a period of parameter adjustment and initial check out,all scientific instruments are now in their normal operating phase.In this paper,the payloads and the initial observation results are introduced. | SUN Huixian WU Ji DAI Shuwu ZHAO Baochang SHU Rong CHANG Jin WANG Huanyu ZHANG Xiaohui REN Qiongying CHEN Xiaomin OUYANG Ziyuan ZOU Yongliao | 2008 | 空间科学学报2008，28，5： | 4 |
| 11 | A Novel Framework for Object-Based Coding and Compression of Hyperspectral Imagery显示文摘A novel object-based framework is proposed for HSI compression, where targets of interest are extracted and separately coded. With objects removed,the holes are filled with the background average to form a new but more homogenous background for better compression. An improved sparse representation with adaptive spatial support is proposed for target detection. By applying the proposed framework to 2D/3D DCT approaches,reconstructed images from conventional and proposed approaches are compared. Six criteria in three groups are employed for quantitative evaluations to measure the degree of data reduction, the distortion of reconstructed image quality and accuracy in target detection, respectively. Comprehensive experiments on two datasets are used for performance evaluation. It is found that the proposed approaches yield much improved results. | ZHAO Chunhui LI Xiaohui REN Jinchang Stephen Marshall | 2015 | Chinese Journal of Electronics2015，24，2： | 4 |
| 12 | Identifying normal embryos from reciprocal translocation carriers by whole chromosome haplotyping显示文摘Reciprocal translocation is a chromosomal structural abnormality that arises when two non-homologous chromosomes rearrange and attach with each other, an incidence that occurs in about 1/500to 1/625 newborns (Mackie and Scriven, 2002). This event typically does not lead to any significant loss of genetic material, thus reciprocal translocation carriers do not exhibit any severe | Zhiqiang Yan Yuqian Wang Yanli Nie Xu Zhi Xiaohui Zhu Meng Qin Shuo Guan Yixin Ren Ying Kuo Di Chang Wei Chen Peng Yuan Liying Yan Jie Qiao | 2018 | Journal of Genetics and Genomics2018，45，9： | 4 |
| 13 | Endoplasmic reticulum stress contributed to β1-adrenoceptor autoantibody-induced reduction of autophagy in cardiomyocytes显示文摘Autophagy reduction has been confirm ed as an im portant mechanism in apoptosis induction.Our previous study showed that decreased autophagy induced by Pi-adrenoceptor autoantibodies(Pi-AAs)enhanced cardiom yocyte apoptosis and contributed to heart failure progression.Endoplasmic reticulum stress(ERS)is known to be an im portant mechanism in intracellular homeostasis and is closely related to autophagy.However,ERS in pi-AA-induced autophagy dysfunction of cardiom yocytes remains unclear.In this study,we used an active im m unization rat model and H9c2 cardiom yocytes to study the role of ERS in Pi-AA-induced autophagy.Results showed that prolonged action of Pi-AAs significantly reduced the autophagy of myocardial tissues and H9c2 cardiom yocytes,and ERS and its related apoptotic pathways were significantly activated.Moreover,mRFP-GFP-LC3 double-labeled adenoviruses were used to detect cardiom yocyte autophagic flux to confirm that Pi-AAs caused a significant decrease in autophagic flux in H9c2 cardiom yocytes.The ERS inhibitor,4-phenylbutyrate(4-PBA),partially attenuated the β1-AA-induced reduction of cardiom yocyte autophagy,consistent w ith the effect of the m am m alian target of rapam ycin inh ibito r rapamycin(Rapa).Compared to the pretreatm ent with 4-PBA or Rapa alone,pretreatm ent w ith the com bination of 4-PBA and Rapa had a greater effect on attenuating the pi-AA-induced decrease in autophagy and Pi-AA-induced apoptosis in cardiomyocytes.This study provides an experim ental basis fo r the role of Pi-AAs in the homeostatic maintenance of cardiom yocytes in patients w ith heart failure w ith respect to autophagy and ERS. | Li Wang Na Ning Changtu Wang Xiaohong Hou Yuan Yuan Yanan Ren Cong Sun Zi Yan Xiaohui Wang Huirong Liu | 2019 | Acta Biochimica et Biophysica Sinica2019，51，10： | 3 |
| 14 | Modification of Cellulose by Hydrophobic Long-chain Molecules: Advances and Prospects显示文摘Cellulose,a natural polymer material with abundant natural sources,is non-toxic,renewable,and biodegradable,making it one of the most promising green materials.Its inherent hydrophilicity dramatically limits the development and application of cellulose products.Hydrophobic modification can significantly change cellulose properties and endow it with additional functions depending on the types of modifying molecules.Controlled modification of cellulose by long-chain hydrophobic molecules is challenging.Significant advances took advantage of new reaction systems and copolymerization.This paper reviews recent innovations in long-chain cellulose hydrophobic modification.A brief value-adding assessment provides a reference for green changes of cellulose to make it fit for future applications. | Yuyuan Wang Haishan Zhang Leyi Lin Rui Wu Xiaohui Wang Junli Ren Chuanfu Liu Xiaoying Wang | 2020 | Paper And Biomaterials2020，5，3： | 3 |
| 15 | Overexpression of angiopoietin-1 reduces doxorubicin-induced apoptosis in cardiomyocytes显示文摘Doxorubicin(Dox) is a major anticancer chemotherapeutic agent.However,it causes cardiomyopathy due to the side effect of cardiomyocyte apoptosis.We have previously reported that angiopoietin-1 significantly reduced myocardial infarction after ischemic injury and protected cardiomyocytes from oxidative stress-induced apoptosis.It is hypothesized that angiopoietin-1 may protect cardiomyocytes from Dox-induced apoptosis.Cardiomyocytes H9C2 were transfected with adenovirus expressing angiopoietin-1(Ad5-Ang-1) 24 h before the cells were challenged with Dox at a concentration of 2 μmol/L.Ad5-GFP served as the vector control.Cardiomyocyte apoptosis was evaluated using Annexin V-FITC staining and caspase-3 and caspase-8 activity was determined by Western blotting.The results showed that Dox treatment significantly induced cardiomyocyte apoptosis as evidenced by the greater number of Annexin V-FITC stained cells and increases in caspase-3 and caspase-8 activity.In contrast,overexpression of angiopoietin-1 significantly prevented Dox-induced cardiomyocyte apoptosis.To elucidate the mechanisms by which angiopoietin-1 protected cells from Dox-induced apoptosis,we analyzed both extrinsic and intrinsic apoptotic signaling pathways.We observed that angiopoietin-1 prevented Dox-induced activation of both extrinsic and intrinsic apoptotic signaling pathways.Specifically,angiopoietin-1 prevented DOX-induced increases in FasL and Bax levels and cleaved caspase-3 and caspase-8 levels in H9C2 cells.In addition,overexpression of angiopoietin-1 also activated the pro-survival phosphoinositide-3 kinase(PI3K)/Akt signaling pathway and decreased Dox-induced nuclear factor-kappaB(NF-κB) activation.Our data suggest that promoting the expression of angiopoietin-1 could be a potential approach for reducing Dox-induced cardiomyocyte cytoxicity. | Danyang Ren Quan Zhu Jiantao Li Tuanzhu Ha Xiaohui Wan Yuehua Li | 2012 | The Journal of Biomedical Research2012，26，6： | 3 |
| 16 | Normal, degenerated, and anomalous-dispersion-like Cerenkov sum-frequency generation in one nonlinear medium显示文摘We report on the experimental realization of Cerenkov sum-frequency generation across the material dispersion in a one-dimensional, periodically poled ferroelectric crystal. Three schemes of sum-frequency generation, confined only in the vicinity of domain walls and in the form of nonlinear Cerenkov radiation, are demonstrated in normal,degenerated, and anomalous-dispersion-like configurations. We exploit their phase-matching geometries, which exhibit a whole scenario of the evolution of Cerenkov radiation varying with the dispersion relationship among the interaction waves. In addition, two sets of conical sum-frequency generation with different radius and center are demonstrated, which result from scattering assistant phase-matching processes. | Ning An Yuanlin Zheng Huaijin Ren Xiaohui Zhao Xuewei Deng Xianfeng Chen | 2015 | Photonics Research2015，3，4： | 2 |
| 17 | Biochar-based Solid Acids as Catalysts for Carbohydrate Hydrolysis: A Critical Review显示文摘Recently, increasing interest has been focused on the hydrolysis of carbohydrates to monosaccharides, among which, glucose and xylose as typical platform sugars can be used to produce chemicals and biofuels. As heterogeneous catalysts, solid acids have gained extensive attention for biomass biorefinery and could replace the conventional process owing to their excellent properties, including acceptable acidity and easy separation. In particular, biochar-based solid acids derived from biomass are promising for biomass conversion owing to the low-cost of feedstocks and the simple preparation procedure. Herein, we attempt to provide a critical overview of biochar-based solid acids for hydrolysis of carbohydrates into glucose and xylose. The preparation methods and properties of biochar-based catalysts as well as the influence of their properties on catalytic performance were discussed in detail. We also highlight the major challenges facing the use of biochar-based solid acids for carbohydrate hydrolysis. | XiaoHui Wang QiXuan Lin YuHuan Yan BangGui Cheng Tao Song JunLi Ren | 2018 | Paper And Biomaterials2018，3，2： | 2 |
| 18 | Family structure and support for the oldest old:A cross-sectional study in Dujiangyan,China显示文摘Objective:In China,adult children have traditionally provided support for their aged parents.This model of care is increasingly challenged by the decline of the extended family.Recently,China’s decades-long one-child policy has eased.We examine the association of family size and composition with family support for nonagenarians and centenarians.Methods:Data were obtained through a questionnaire survey of 619 nonagenarians and cen-tenarians in Dujiangyan and were analyzed by chi-square tests,Student t tests,and multivariate logistic regression models.Results:This study revealed that an increased number of offspring might provide financial support for older people,but this does not necessarily translate into physical and emotional care.Conclusion:It is clear that although alternative sources of support for older people are in-creasingly needed,in China the family will continue to play an important role in supporting older people. | Xiaohui Ren Hongdao Meng Chaojie Liu Jinhui Wu Birong Dong Ningxiu Li | 2015 | Family Medicine and Community Health2015，3，4： | 2 |
| 19 | RanBPM is an acetylcholinesterase-interacting protein that translocates into the nucleus during apoptosis显示文摘Acetylcholinesterase (疼痛) 表示可以在各种各样的房间类型在 apoptosis 期间被导致。这里,我们使用了疼痛的 C 终端屏蔽人的胎儿的大脑图书馆并且发现它在组织微导管的中心(RanBPM ) 与跑绑定蛋白质交往了。这个相互作用被 coimmunoprecipitation 分析进一步证实。在 HEK293T 房间, RanBPM 和疼痛不同类地在 cisplatin 未经治疗的细胞质的摘录并且在对待 cisplatin 的细胞质或原子的摘录被表示。我们用词法方法执行的以前的研究在 apoptosis 期间从细胞质显示出那疼痛 translocates 到原子核。一起拿,这些结果建议 RanBPM 是在 apoptosis 期间是从进原子核的细胞质的 translocated 的交往疼痛的蛋白质,类似于在疼痛的情况下观察的 translocation。 | Xiaowen Gong Weiyuan Ye Haibo Zhou Xiaohui Ren Zhigang Li Weiyin Zhou Jun Wu Yicheng Gong Qi Ouyang Xiaolin Zhao Xuejun Zhang | 2009 | Acta Biochimica et Biophysica Sinica2009，41，11： | 2 |
| 20 | 2021 Chinese consensus on the diagnosis and management of primary immune thrombocytopenia in pregnancy显示文摘Immune thrombocytopenia(ITP)is an acquired disease characterized by isolated thrombocytopenia,which is one of the most common causes of thrombocytopenia during pregnancy.Women with ITP who have severe thrombocytopenia are at an increased risk for life-threatening obstetric complications.Therefore,we established this consensus statement on the diagnosis and management of ITP during pregnancy(detailed information is available in the Supplementary File,http://gffzz16e312a87a7141a5hu95vw5xucc6c60pw.ffgz.tsg.suse.edu.cn/A978). | Zhang Xiaohui Chen Fangping Chen Xiequn Cheng Yunfeng Fang Meiyun Feng Jianming Fu Haixia Gao Hong Han Yue He Aili Hou Ming Hu Yu Huang Ruibin Huang Wenrong Jing Zhicheng Kong Peiyan Liang Aibin Liang Meiying Liu Daihong Liu Junling Liu Lin Liu Xiaowei Ma Liangming Mei Heng Ni Heyu Niu Ting Peng Jun Qiao Jianlin Ren Jinhai Song Yongping Tang Liang V Tong Tong Wang Shaoyuan Wang Xin Wang Zhao Wei Hui Wu Depei Wu Guangsheng Xu Caigang Xu Xue Xu Yajing Yang Linhua Yang Renchi Yang Tonghua Yin Chenghong Yu Li Zhang Guangsen Zhang Lei Zhang Liansheng Zhang Xi Zhao Weili Zhao Yongqiang Zhou Daobin Zhou Hu Zhou Zeping Zhu Tienan Wang Jianliu Huang Xiaojun | 2022 | Chinese Medical Journal2022，，8： | 2 |
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