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| 1 | Appropriateness of outpatient gastrointestinal endoscopy in a non-academic hospital显示文摘AIM:To assess the appropriate use and the diagnostic yield of upper gastrointestinal endoscopy and colonoscopy in this subgroup of patients.METHODS:In total,789 consecutive outpatients referred for gastrointestinal(GI) endoscopy [381 for esophagogastroduodenoscopy(EGD) and 408 for colonoscopy] were prospectively enrolled in the study.The American Society for Gastrointestinal Endoscopy(ASGE) guidelines were used to assess the relationship between appropriateness and the presence of relevant endoscopic f indings.RESULTS:The overall inappropriate rate was 13.3%.The indications for EGD and colonoscopy were,respectively,appropriate in 82.7% and 82.6% of the exams,uncertain in 5.8% and 2.4% and inappropriate in 11.5% and 15%.The diagnostic yield was signif icant higher forEGDs and colonoscopies judged appropriate and uncertain when compared with those considered inappropriate(EGD:36.6% vs 36.4% vs 11.4%,P = 0.004;Colonoscopy:24.3% vs 20.0% vs 3.3%,P = 0.001).Of the 25 malignant lesions detected,all but one was detected in exams judged appropriate or uncertain.CONCLUSION:This study shows a good adherence to ASGE guidelines by the referring physicians and a significant increase of the diagnostic yield in appropriate examinations,namely in detecting neoplastic lesions.It underscores the importance that the appropriateness of the indication assumes in assuring high-quality GI endoscopic procedures. | Joo Mangualde Marie I Cremers Ana M Vieira Ricardo Freire lia Gamito Cristina Lobato Ana L Alves Fátima Augusto Ana P Oliveira | 2011 | World Journal of Gastrointestinal Endoscopy2011，3，10： | 2 |
| 2 | Dendritic cell deficiencies persist seven months after SARS-CoV-2 infection显示文摘Severe Acute Respiratory Syndrome Coronavirus(SARS-CoV)-2 infection induces an exacerbated inflammation driven by innate immunity components.Dendritic cells(DCs)play a key role in the defense against viral infections,for instance plasmacytoid DCs(pDCs),have the capacity to produce vast amounts of interferon-alpha(IFN-α).In COVID-19 there is a deficit in DC numbers and IFN-αproduction,which has been associated with disease severity.In this work,we described that in addition to the DC deficiency,several DC activation and homing markers were altered in acute COVID-19 patients,which were associated with multiple inflammatory markers.Remarkably,previously hospitalized and nonhospitalized patients remained with decreased numbers of CD1c+myeloid DCs and pDCs seven months after SARS-CoV-2 infection.Moreover,the expression of DC markers such as CD86 and CD4 were only restored in previously nonhospitalized patients,while no restoration of integrinβ7 and indoleamine 2,3-dyoxigenase(IDO)levels were observed.These findings contribute to a better understanding of the immunological sequelae of COVID-19. | Alberto Pérez-Gómez Joana Vitallé Carmen Gasca-Capote Alicia Gutierrez-Valencia María Trujillo-Rodriguez Ana Serna-Gallego Esperanza Muñoz-Muela María de los Reyes Jiménez-Leon Mohamed Rafii-El-Idrissi Benhnia Inmaculada Rivas-Jeremias Cesar Sotomayor Cristina Roca-Oporto Nuria Espinosa Carmen Infante-Domínguez Juan Carlos Crespo-Rivas Alberto Fernández-Villar Alexandre Pérez-González Luis Fernando López-Cortés Eva Poveda Ezequiel Ruiz-Mateos JoséMiguel Cisneros Sonsoles Salto-Alejandre Judith Berastegui-Cabrera Pedro Camacho-Martínez Carmen Infante-Domínguez Marta Carretero-Ledesma Juan Carlos Crespo-Rivas Eduardo Márquez JoséManuel Lomas Claudio Bueno Rosario Amaya JoséAntonio Lepe Jerónimo Pachón Elisa Cordero Javier Sánchez-Céspedes Manuela Aguilar-Guisado Almudena Aguilera Clara Aguilera Teresa Aldabo-Pallas Verónica Alfaro-Lara Cristina Amodeo Javier Ampuero María Dolores Avilés Maribel Asensio Bosco Barón-Franco Lydia Barrera-Pulido Rafael Bellido-Alba Máximo Bernabeu-Wittel Candela Caballero-Eraso Macarena Cabrera Enrique Calderón Jesús Carbajal-Guerrero Manuela Cid-Cumplido Yael Corcia-Palomo Juan Delgado Antonio Domínguez-Petit Alejandro Deniz Reginal Dusseck-Brutus Ana Escoresca-Ortega Fátima Espinosa Nuria Espinosa Michelle Espinoza Carmen Ferrándiz-Millón Marta Ferrer Teresa Ferrer Ignacio Gallego-Texeira Rosa Gámez-Mancera Emilio García Horacio García-Delgado Manuel García-Gutiérrez María Luisa Gascón-Castillo Aurora González-Estrada Demetrio González Carmen Gómez-González Rocío González-León Carmen Grande-Cabrerizo Sonia Gutiérrez Carlos Hernández-Quiles Inmaculada Concepción Herrera-Melero Marta Herrero-Romero Luis Jara Carlos Jiménez-Juan Silvia Jiménez-Jorge Mercedes Jiménez-Sánchez Julia Lanseros-Tenllado Carmina López Isabel López Álvaro López-Barrios Luis F.López-Cortés Rafael Luque-Márquez Daniel Macías-García Guillermo Martín-Gutiérrez Luis Martín-Villén JoséMolina Aurora Morillo María Dolores Navarro-Amuedo Dolores Nieto-Martín Francisco Ortega María Paniagua-García Amelia Peña-Rodríguez Esther Pérez Manuel Poyato Julia Praena-Segovia Rafaela Ríos Cristina Roca-Oporto Jesús F.Rodríguez María Jesús Rodríguez-Hernández Santiago Rodríguez-Suárez Ángel Rodríguez-Villodres Nieves Romero-Rodríguez Ricardo Ruiz Zida Ruiz de Azua Celia Salamanca Sonia Sánchez Víctor Manuel Sánchez-Montagut César Sotomayor Alejandro Suárez Benjumea Javier Toral | 2021 | Cellular & Molecular Immunology2021，18，9： | 2 |
| 3 | Supercritical fluid extraction of lipids from spent coffee grounds显示文摘 | Ricardo M C Joao F Gomes da Silva M D R | 2009 | Journal of Supercritical Fluids2009，51，： | 1 |
| 4 | Mathematical modeling and experimental results of a sandwich-type amperometric biosensor 显示文摘 | RICARDO R M BARUZZI A M GARAY F | 2012 | Sensors and Actuators B - Chemical2012，162，1： | 1 |
| 5 | Geographic distribution of vacA allelic types of Helicobacter pylori显示文摘 | Leen–Jan Van Doorn Céu Figueiredo Francis Mégraud Salvador Pena Peter Midolo Dulciene Maria De Magalh?es Queiroz Fátima Carneiro Bart Vanderborght Maria Da Glória F. Pegado Ricardo Sanna Wink De Boer Peter M. Schneeberger Pelayo Correa Enders K.W. Ng John | 1999 | Gastroenterology1999，，4： | 1 |
| 6 | Young age is an independent prognostic factor for survival of sporadic renal cell carcinoma显示文摘 | Ricardo F S Charles J R Lydia T M | 2004 | J Urol2004，171，61： | 1 |
| 7 | Isolation and characterization of polysaccharides from Agaricus blazei Murill显示文摘 | GONZAGA M L C RICARDO N M P S HEATLEY F | 2005 | Carbohydrate Polymers2005，60，1： | 1 |
| 8 | Spatially-resolved EELS analysis of antibody distribution on biofunctionalized magnetic nanoparticles显示文摘 | Raul A Laura D M Laura C Alvaro M Marcel T Valeria G Jesus M D L F Clara M Ricardo 1 | 2013 | ACS Nano2013，7，5： | 1 |
| 9 | Influence of extrusion temperature on the microstructure and the texture of 6061Al-15% SiCw PM composites显示文摘 | BORREGO A RICARDO F CRISTINA M C IBANE J GASPAR G D | 2002 | Compos Sci Technol2002，62，： | 1 |
| 10 | Mycophenolate mofetil prevents the development of glomerular injury in experiment diabetes 显示文摘 | Ricardo U Clarice K F Ana L M | 2003 | Kidney Int2003，63，4： | 1 |
| 11 | BolA inhibits cell elongation and regulates MreB expression levels 显示文摘 | PATRICK F RICARDO N M CECILIA M A | 2009 | J Mol Biol2009，385，5： | 1 |
| 12 | Isolation and characterization of polysaccharides from Agaricus blazei Murill显示文摘 | Gonzaga M L C Ricardo N M Heatley F | 2005 | Carbohydr Polym2005，60，1： | 1 |
| 13 | Hysteretic modelsthat incorporate strength and stiffness deterioration显示文摘 | Luis F I Ricardo A M Helmut K | 2005 | Earthquake Engineering and Structural Dynamics2005，34，12： | 1 |
| 14 | Mycophenolate mofetil prevents the developmeat of glomerular injury in experimental diabet-es显示文摘 | Ricardo U Clarice K F Lueia M | 2003 | Kid Int2003，63，： | 1 |
| 15 | Catechin and procyanidin Composition of Seeds from Grape Cultivars Grown in Ontario显示文摘 | TIBOR F JORGE M RICARDO S | 1997 | J Agric Food Chem1997，45，： | 1 |
| 16 | Catechin and procyanidin composition ofseeds from grape cultivars grown in ontario显示文摘 | TIBOR F RICARDO D SILVA J M | 1997 | J Agric Food Chem1997，45，： | 1 |
| 17 | Focussed microwave-assisted sample preparation:Total phenol determination in petroleum refinery effluents by flow injection spectrophotometry显示文摘 | Quaresmaa M C B Cassellab R J Carvalhoc M F B Ricardo E Santelli R E | 2004 | Microchemical Journal2004，78，： | 1 |
| 18 | Catechin and Procyanidin Composition of Seeds from Grape Cultivars Grown in Ontario显示文摘 | TIBOR F JORGE M RICARDO da S | 1997 | J Agric Food Chem1997，45，： | 1 |
| 19 | Catechin and procyanidin composition of seeds from grape cultivars gown in Ontario 显示文摘 | TIBOR F JORGE M RICARDO S | 1997 | J Agr Food Chem1997，45，： | 1 |
| 20 | Oxide nanoparticle reservoirs for storage and prolonged release of corrosion inhibitors 显示文摘 | ZHELUDKEVICH M L SERRA Ricardo MONTEMOR M F | 2005 | Electrochem Commun2005，7，8： | 1 |
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