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29篇 您的检索式:作者名="ROHIT P"
    题名 作者 年代 出处 被引量
1Combination immunotherapy with Survivin and luteinizing hormone-releasing hormone fusion protein in murine breast cancer model显示文摘AIM To investigate the therapeutic potential of two recombinant proteins, Survivin and luteinizing hormone-releasing hormone (LHRH) fusion protein [LHRH(6 leu)-LTB] for immunotherapy of breast cancer.METHODS Murine 4 T-1 breast cancer model was used to evaluate the efficacy of recombinant proteins in vivo. Twenty four Balb/c mice were divided into 4 groups of 6 mice each. Recombinant Survivin and LHRH fusion protein, alone or in combination, were administered along with immunomodulator Mycobacterium indicus pranii (MIP) in Balb/c mice. Unimmunized or control group mice were administered with phosphate buffer saline. Each group was then challenged with syngeneic 4 T-1 cells to induce the growth of breast tumor. Tumor growth was monitored to evaluate the efficacy of immune-response in preventing the growth of cancer cells.RESULTS Preventive immunization with 20 μg recombinant Survivin and MIP was effective in suppressing growth of 4 T-1 mouse model of breast cancer (P = 0.04) but 50 μg dose was ineffective in suppressing tumor growth. However, combination of Survivin and LHRH fusion protein was more effective in suppressing tumor growth (P = 0.02) as well as metastasis in vivo in comparison to LHRH fusion protein as vaccine antigen alone.CONCLUSION Recombinant Survivin and MIP suppress tumor growth significantly. Combining LHRH fusion protein with Survivin and MIP enhances tumor suppressive effects marginally which provides evidence for recombinant Survivin and LHRH fusion protein as candidates for translating the combination cancer immunotherapy approaches.Himani Garg Rohit Singh Hada Jagdish C Gupta G P Talwar Shweta Dubey 2018World Journal of Clinical Oncology2018,9,8:2
2A comparative evalua- tion of the performance characteristics of a spark ignition engine using hydrogen and compressed natural gas as al- ternative fuels 显示文摘Das L M Gulati Rohit Gupta P K 2000International Journal of Hydrogen En- ergy2000,25,8:1
3A comparative evaluation of the performance characteristics of a spark ignition engine using hydrogen and compressed natural gas as alternative fuels 显示文摘Das L M Gulati Rohit Gupta P K 2000International Journal of Hydrogen Energy2000,25,8:1
4The Los Angeles Latino Eye Study显示文摘Rohit Varma Sylvia H Paz Stanley P Azen Ronald Klein Denise Globe Mina Torres Chrisandra Shufelt Susan Preston-Martin 2004Ophthalmology2004,,6:1
5Diagnosis of tuberculosis under RNTCP:examination of two or three sputum specimens显示文摘Rohit Sarin Mukerjee S Neeta Singla Sharma P P 2001Indian J Tuberc2001,48,1:1
6Thermal protective performance nf protective clothing used for low radiant heat pro- tection 显示文摘SONGG W STEPHEN P ROHIT S et al 2011Textile Research Journal February2011,81,3:1
7Fermentation of biomass-generated producer gas to ethanol 显示文摘Rohit P D Rustin M S Bruno G C 2004Biotechnology and Bioengineering2004,86,5:1
8Impact of Dust on Solar Photovoltaic(PV)Performance:Research Status,Challenges and Recommendations显示文摘MONTO M ROHIT P 2010Renewable and Sustainable Energy Reviews2010,14,:1
9An overview of MIMO communication--A key to gigabit wireless显示文摘Arogyaswami J P Dhananjay A G Rohit U N 2004Proceedings of the IEEE2004,92,2:1
10Temperature in- duced stress influence on biodiesel productivity during mixotrophic microalgae cuhivation with wastewater 显示文摘Venkata Subhash G Rohit M V Devi M P 2014Bioresource Technolo- gy2014,169,:1
11A randomized, placebocontrolled, double-blind, crossover study to evaluate the efficacy of oval sildenafil therapy in severe pulmonary artery hypertension 显示文摘Tarvinder P Sing h Manojkumar Rohit 2006Ameriecan Heart Journal2006,151,4:1
12Superficial Temporal Fascia Pedicled V-Y Advancement Flap for Scalp Reconstruction 显示文摘Rohit S Deepika S Sengupta P 2010J Maxillofac Oral Surg2010,9,4:1
13Constrained nonlinear MPC using hammerstein and wiener models:PLS framework显示文摘ROHIT S P LAKSHMINARAYANAN S SHAH S L 1998AICHE1998,44,7:1
14Utility-directed resource allocation in virtual desktop clouds显示文摘PRASAD C ROHIT P ALEX B 0,,18:1
15Phase change microvalve for integrated devices显示文摘ROHIT P MING Y BRIAN N J 2004Analytical Chemistry2004,76,13:1
16Idiopathic spontaneous coro- nary artery dissection presenting as acute myocardial infarction in a young boy显示文摘Rohit M K Garg P K Hariram V 2008Indian Heart J2008,60,4:1
17Cerebral Hemodynamics in the Presence of Decreased SystemicVenous Compliance in Patients with Fontan Physiology MayLimit Anaerobic ExerciseCapacity显示文摘Rohit P Rao Michael J 0,,:1
18Superficial temporal fascia pedicled v-y advancement flap for scalp reconstruction 显示文摘Rohit S Sirohi D Sengupta P 2010J Maxillofac Oral Surg2010,9,4:1
19Mycoplasma hominis and ureaplasma species brain abscess in a neonate显示文摘Rohit P Rao Nancy S Ghanayem Bruce A Kaufman 2002Journal of Pediatric Infectious Disease2002,21,11:1
20A Comparative Evaluation of the Performance Characteristics of a Spark Ignition Engine Using Hydrogen and Compressed Natural Gas as Alternative Fuels显示文摘Das L M Rohit Gulati Gupta P K 2000Hydrogen Energy2000,25,:1
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